DE69813322D1 - Flüssige gonadotropinhaltige Arzneimittel - Google Patents

Flüssige gonadotropinhaltige Arzneimittel

Info

Publication number
DE69813322D1
DE69813322D1 DE69813322T DE69813322T DE69813322D1 DE 69813322 D1 DE69813322 D1 DE 69813322D1 DE 69813322 T DE69813322 T DE 69813322T DE 69813322 T DE69813322 T DE 69813322T DE 69813322 D1 DE69813322 D1 DE 69813322D1
Authority
DE
Germany
Prior art keywords
liquid medicines
medicines containing
containing gonadotropin
gonadotropin
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69813322T
Other languages
English (en)
Other versions
DE69813322T2 (de
Inventor
A T P Skrabanja
Den Oetelaar P J M Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Application granted granted Critical
Publication of DE69813322D1 publication Critical patent/DE69813322D1/de
Publication of DE69813322T2 publication Critical patent/DE69813322T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69813322T 1997-01-15 1998-01-13 Flüssige gonadotropinhaltige Arzneimittel Expired - Lifetime DE69813322T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97200099 1997-01-15
EP97200099 1997-01-15

Publications (2)

Publication Number Publication Date
DE69813322D1 true DE69813322D1 (de) 2003-05-22
DE69813322T2 DE69813322T2 (de) 2004-02-19

Family

ID=8227932

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69813322T Expired - Lifetime DE69813322T2 (de) 1997-01-15 1998-01-13 Flüssige gonadotropinhaltige Arzneimittel
DE122010000011C Pending DE122010000011I1 (de) 1997-01-15 1998-01-13 Flüssige gonadotropinhaltige Arzneimittel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE122010000011C Pending DE122010000011I1 (de) 1997-01-15 1998-01-13 Flüssige gonadotropinhaltige Arzneimittel

Country Status (30)

Country Link
US (1) US5929028A (de)
EP (2) EP1285665A1 (de)
JP (1) JP4353549B2 (de)
KR (1) KR100498531B1 (de)
CN (1) CN1165341C (de)
AR (1) AR011410A1 (de)
AT (1) ATE237348T1 (de)
AU (1) AU736339B2 (de)
BR (1) BR9800323B1 (de)
CA (1) CA2226803A1 (de)
CZ (1) CZ297419B6 (de)
DE (2) DE69813322T2 (de)
DK (1) DK0853945T3 (de)
ES (1) ES2196474T3 (de)
FR (1) FR10C0024I2 (de)
HK (1) HK1010150A1 (de)
HU (1) HU227154B1 (de)
ID (1) ID19499A (de)
IL (1) IL122732A0 (de)
LU (1) LU91655I2 (de)
MX (1) MX9800438A (de)
NO (3) NO322509B1 (de)
NZ (1) NZ329572A (de)
PL (1) PL190103B1 (de)
PT (1) PT853945E (de)
RU (1) RU2203086C2 (de)
SA (1) SA98181124B1 (de)
TR (1) TR199800062A2 (de)
TW (1) TW518235B (de)
ZA (1) ZA9883B (de)

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US20030166525A1 (en) 1998-07-23 2003-09-04 Hoffmann James Arthur FSH Formulation
JP2007204498A (ja) * 1999-03-01 2007-08-16 Chugai Pharmaceut Co Ltd 長期安定化製剤
JP2000247903A (ja) * 1999-03-01 2000-09-12 Chugai Pharmaceut Co Ltd 長期安定化製剤
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US20030104996A1 (en) * 2001-08-30 2003-06-05 Tiansheng Li L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
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US20040248784A1 (en) * 2003-06-03 2004-12-09 Marco Filicori Unitary combinations of FSH and hCG
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Also Published As

Publication number Publication date
CZ297419B6 (cs) 2006-12-13
PL324279A1 (en) 1998-07-20
HU227154B1 (en) 2010-08-30
TW518235B (en) 2003-01-21
IL122732A0 (en) 1998-08-16
CN1165341C (zh) 2004-09-08
NO980177L (no) 1998-07-16
BR9800323A (pt) 1999-06-29
NO2010013I1 (no) 2010-06-07
CZ13598A3 (cs) 1998-08-12
ID19499A (id) 1998-07-16
KR19980070493A (ko) 1998-10-26
HK1010150A1 (en) 1999-06-17
EP0853945A1 (de) 1998-07-22
CA2226803A1 (en) 1998-07-15
JP4353549B2 (ja) 2009-10-28
ATE237348T1 (de) 2003-05-15
BR9800323B1 (pt) 2011-04-19
MX9800438A (es) 1998-11-30
HUP9800056A2 (hu) 1998-08-28
SA98181124B1 (ar) 2006-07-10
DE69813322T2 (de) 2004-02-19
FR10C0024I2 (fr) 2011-04-01
NO2021001I1 (no) 2021-01-12
HU9800056D0 (en) 1998-03-02
PL190103B1 (pl) 2005-10-31
DE122010000011I1 (de) 2010-07-08
EP0853945B1 (de) 2003-04-16
HUP9800056A3 (en) 2001-01-29
ES2196474T3 (es) 2003-12-16
LU91655I2 (fr) 2010-04-26
NO980177D0 (no) 1998-01-14
CN1191139A (zh) 1998-08-26
DK0853945T3 (da) 2003-08-04
FR10C0024I1 (de) 2010-05-21
NO322509B1 (no) 2006-10-16
PT853945E (pt) 2003-08-29
NO2010013I2 (no) 2015-05-18
NZ329572A (en) 1999-05-28
ZA9883B (en) 1998-07-08
AU736339B2 (en) 2001-07-26
EP1285665A1 (de) 2003-02-26
AU5205998A (en) 1998-07-23
AR011410A1 (es) 2000-08-16
RU2203086C2 (ru) 2003-04-27
US5929028A (en) 1999-07-27
KR100498531B1 (ko) 2005-09-30
TR199800062A2 (xx) 1998-08-21
JPH10203997A (ja) 1998-08-04

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