ES2196474T3 - Formulaciones liquidas que contienen una gonadotropina. - Google Patents
Formulaciones liquidas que contienen una gonadotropina.Info
- Publication number
- ES2196474T3 ES2196474T3 ES98200068T ES98200068T ES2196474T3 ES 2196474 T3 ES2196474 T3 ES 2196474T3 ES 98200068 T ES98200068 T ES 98200068T ES 98200068 T ES98200068 T ES 98200068T ES 2196474 T3 ES2196474 T3 ES 2196474T3
- Authority
- ES
- Spain
- Prior art keywords
- gonadotropine
- thioeter
- preferibly
- salt
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA INVENCION CONCIERNE UNA FORMULACION DE GONADOTROPINA LIQUIDA QUE SE CARACTERIZA PORQUE LA FORMULACION COMPRENDE UNA GONADOTROPINA Y CANTIDADES ESTABILIZANTES DE UN ACIDO POLICARBOXILICO, O UNA SAL DE ESTE, Y DE UN COMPUESTO TIOETER. LAS PROTEINAS PARTICULARES (POR EJEMPLO, LH, TSH, FSH O HCG) ESTAN EN MEZCLA CON LOS ESTABILIZADORES PARTICULARES EN UNA SOLUCION ACUOSA. LAS PREPARACIONES CONTIENEN UNA SUFICIENTE CANTIDAD DEL ACIDO POLICARBOXILICO O UNA SAL DE ESTE, PREFERIBLEMENTE CITRATO SODICO, Y UNA CANTIDAD SUFICIENTE DEL COMPUESTO TIOETER, PREFERIBLEMENTE METIONINA, PARA ESTABILIZAR LA PROTEINA. LAS PREPARACIONES TAMBIEN INCLUYEN PREFERIBLEMENTE UN DISACARIDO NO REDUCTOR COMO SACAROSA Y UNSURFACTANTE NO IONICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97200099 | 1997-01-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2196474T3 true ES2196474T3 (es) | 2003-12-16 |
Family
ID=8227932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98200068T Expired - Lifetime ES2196474T3 (es) | 1997-01-15 | 1998-01-13 | Formulaciones liquidas que contienen una gonadotropina. |
Country Status (30)
Country | Link |
---|---|
US (1) | US5929028A (es) |
EP (2) | EP0853945B1 (es) |
JP (1) | JP4353549B2 (es) |
KR (1) | KR100498531B1 (es) |
CN (1) | CN1165341C (es) |
AR (1) | AR011410A1 (es) |
AT (1) | ATE237348T1 (es) |
AU (1) | AU736339B2 (es) |
BR (1) | BR9800323B1 (es) |
CA (1) | CA2226803A1 (es) |
CZ (1) | CZ297419B6 (es) |
DE (2) | DE69813322T2 (es) |
DK (1) | DK0853945T3 (es) |
ES (1) | ES2196474T3 (es) |
FR (1) | FR10C0024I2 (es) |
HK (1) | HK1010150A1 (es) |
HU (1) | HU227154B1 (es) |
ID (1) | ID19499A (es) |
IL (1) | IL122732A0 (es) |
LU (1) | LU91655I2 (es) |
MX (1) | MX9800438A (es) |
NO (3) | NO322509B1 (es) |
NZ (1) | NZ329572A (es) |
PL (1) | PL190103B1 (es) |
PT (1) | PT853945E (es) |
RU (1) | RU2203086C2 (es) |
SA (1) | SA98181124B1 (es) |
TR (1) | TR199800062A2 (es) |
TW (1) | TW518235B (es) |
ZA (1) | ZA9883B (es) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU776823B2 (en) * | 1998-07-23 | 2004-09-23 | Ares Trading S.A. | FSH and FSH variant formulations, products and methods |
US20030166525A1 (en) | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
JP2007204498A (ja) * | 1999-03-01 | 2007-08-16 | Chugai Pharmaceut Co Ltd | 長期安定化製剤 |
JP2000247903A (ja) | 1999-03-01 | 2000-09-12 | Chugai Pharmaceut Co Ltd | 長期安定化製剤 |
ATE386501T1 (de) * | 1999-07-12 | 2008-03-15 | Sandoz Ag | Formulierungen von wachstumshormonen |
EA004385B1 (ru) * | 2000-02-22 | 2004-04-29 | Апплайд Резеч Системз Арс Холдинг Н.В. | Способ выделения лютеинизирующего гормона |
US7256184B2 (en) * | 2000-10-16 | 2007-08-14 | Rodriguez Victorio C | Treatment of aging disorders in humans |
AU2007200662A1 (en) * | 2001-08-30 | 2007-03-08 | Kirin-Amgen, Inc. | L-methionine as a stabilizer for NESP/EPO in HSA-free formulations |
US20030104996A1 (en) * | 2001-08-30 | 2003-06-05 | Tiansheng Li | L-methionine as a stabilizer for NESP/EPO in HSA-free formulations |
EP1346843A1 (en) * | 2002-03-22 | 2003-09-24 | Fuji Photo Film Co., Ltd. | Image forming method |
CA2518268C (en) | 2003-03-04 | 2013-12-10 | Aspenbio, Inc. | Methods and kits for maintaining pregnancy, treating follicular cysts, and synchronizing ovulation using luteinizing hormone |
DK1610822T4 (en) | 2003-04-02 | 2019-01-14 | Ares Trading Sa | Liquid pharmaceutical FSH and LH formulations together with a nonionic surfactant |
US20040248784A1 (en) * | 2003-06-03 | 2004-12-09 | Marco Filicori | Unitary combinations of FSH and hCG |
CA2526099C (en) * | 2003-06-20 | 2013-02-05 | Ares Trading Sa | Freeze-dried fsh / lh formulations |
JP4412989B2 (ja) * | 2003-12-15 | 2010-02-10 | 株式会社日立製作所 | 複数の記憶システムを有するデータ処理システム |
KR100587535B1 (ko) * | 2004-02-04 | 2006-06-08 | 충남대학교산학협력단 | 재조합 hFSH 유전자 및 이를 내장하는 발현용 벡터 |
TWI369401B (en) | 2005-07-05 | 2012-08-01 | Ares Trading Sa | Serum-free culture medium for the production of recombinant gonadotropins |
KR101105871B1 (ko) * | 2005-09-27 | 2012-01-16 | 주식회사 엘지생명과학 | 인 난포자극호르몬의 안정한 용액 제형 |
US8168206B1 (en) | 2005-10-06 | 2012-05-01 | Allergan, Inc. | Animal protein-free pharmaceutical compositions |
US8137677B2 (en) * | 2005-10-06 | 2012-03-20 | Allergan, Inc. | Non-protein stabilized clostridial toxin pharmaceutical compositions |
WO2007056851A1 (en) * | 2005-11-17 | 2007-05-24 | Mount Sinai Hospital | Compositions and methods for enhancing ovulation inducing agents |
US9458444B2 (en) | 2006-02-03 | 2016-10-04 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
US10221228B2 (en) | 2006-02-03 | 2019-03-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
US20140113860A1 (en) | 2006-02-03 | 2014-04-24 | Prolor Biotech Ltd. | Long-acting polypeptides and methods of producing and administering same |
US10351615B2 (en) | 2006-02-03 | 2019-07-16 | Opko Biologics Ltd. | Methods of treatment with long-acting growth hormone |
US8450269B2 (en) * | 2006-02-03 | 2013-05-28 | Prolor Biotech Ltd. | Long-acting growth hormone and methods of producing same |
US8048849B2 (en) | 2006-02-03 | 2011-11-01 | Modigene, Inc. | Long-acting polypeptides and methods of producing same |
US9249407B2 (en) | 2006-02-03 | 2016-02-02 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
US8946155B2 (en) | 2006-02-03 | 2015-02-03 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
US20150038413A1 (en) | 2006-02-03 | 2015-02-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
WO2008038817A1 (en) * | 2006-09-25 | 2008-04-03 | National University Corporation Tokyo University Of Agriculture And Technology | Ultrasonic operation device and microtube inside system |
KR20080106636A (ko) * | 2007-06-04 | 2008-12-09 | 동아제약주식회사 | 사람 융모성 성선자극호르몬 함유 즉시 사용형 주사 용액 |
US7951368B2 (en) * | 2007-06-25 | 2011-05-31 | Amgen Inc. | Compositions of specific binding agents to hepatocyte growth factor |
JP5570980B2 (ja) | 2007-06-28 | 2014-08-13 | ラティオファーム ゲーエムベーハー | Fsh生産細胞クローン |
JP5551601B2 (ja) * | 2007-11-01 | 2014-07-16 | メルク セローノ ソシエテ アノニム | Lh液体調製物 |
ME01337B (me) * | 2008-02-08 | 2013-12-20 | Biogenerix Ag | Tečni preparat fsh |
TWI488640B (zh) | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
CN102309745B (zh) * | 2008-09-17 | 2013-05-08 | 上海天伟生物制药有限公司 | 一种卵泡刺激素冻干针剂 |
CN101347613B (zh) * | 2008-09-17 | 2011-10-26 | 上海天伟生物制药有限公司 | 几乎不含亚基的糖蛋白的组合物及其制备方法 |
ES2548378T3 (es) * | 2008-11-04 | 2015-10-16 | Aska Pharmaceutical Co., Ltd. | Composición acuosa que contiene hormona foliculoestimulante |
US9663778B2 (en) | 2009-07-09 | 2017-05-30 | OPKO Biologies Ltd. | Long-acting coagulation factors and methods of producing same |
TWI532495B (zh) * | 2009-10-05 | 2016-05-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
EP2325194A1 (en) | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Process for the purification of glycoproteins |
EP2417982A1 (en) * | 2010-07-30 | 2012-02-15 | Ferring B.V. | Stabilization of gonadotropins |
WO2012127500A2 (en) * | 2011-03-11 | 2012-09-27 | Sanzyme Limited | Composition for spermatogenesis |
WO2012127501A2 (en) * | 2011-03-11 | 2012-09-27 | Sanzyme Limited | Composition for improving endometrial thickness during ovarian stimulation |
EP2691119B1 (en) | 2011-03-31 | 2018-08-01 | Ferring B.V. | Pharmaceutical preparation |
US8680086B2 (en) | 2011-04-15 | 2014-03-25 | Neuralight Hd, Llc | Methods for chronic pain management and treatment using HCG |
US20120265129A1 (en) | 2011-04-15 | 2012-10-18 | Neuralight Hd, Llc | Methods for Chronic Pain Management and Treatment using HCG |
WO2013010840A2 (en) | 2011-07-18 | 2013-01-24 | Arts Biologics A/S | Long acting biologically active luteinizing hormone (lh) compound |
JO3092B1 (ar) | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
BR112014025951A2 (pt) | 2012-04-19 | 2017-07-11 | Opko Biologics Ltd | variantes de oxintomodulina de longa ação e métodos de produção do mesmo |
BR112015008753A2 (pt) | 2012-10-18 | 2017-07-04 | Neuralight Hd Llc | tratamento de depressão e ptsd |
CN112661863A (zh) | 2012-11-20 | 2021-04-16 | 奥普科生物制品有限公司 | 通过连接至促性腺激素羧基端肽来增加多肽的流体动力学体积的方法 |
ES2694328T3 (es) | 2013-03-12 | 2018-12-19 | Sumitomo Dainippon Pharma Co., Ltd. | Composición acuosa líquida |
US20160024181A1 (en) | 2013-03-13 | 2016-01-28 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
US20150158926A1 (en) | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
IN2013MU03559A (es) | 2013-11-12 | 2015-07-24 | Cadila Healthcare Ltd | |
SI3209319T1 (sl) * | 2014-10-21 | 2022-01-31 | Hexima Limited | Postopek zdravljenja glivičnih okužb |
EP3310347B1 (en) | 2015-06-19 | 2021-08-04 | OPKO Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
GB201603280D0 (en) * | 2016-02-24 | 2016-04-13 | Ferring Bv | Stable liquid gonadotropin formulation |
KR20240006077A (ko) | 2016-07-11 | 2024-01-12 | 옵코 바이오로직스 리미티드 | 지속성 응고 인자 vii 및 그 제조 방법 |
EP3436054B2 (en) | 2016-09-13 | 2022-07-27 | Allergan, Inc. | Stabilized non-protein clostridial toxin compositions |
US11110063B2 (en) | 2017-08-25 | 2021-09-07 | MAIA Pharmaceuticals, Inc. | Storage stable sincalide formulations |
BR112021022860A2 (pt) | 2019-05-16 | 2022-01-18 | Ceva Sante Animale | Composições e métodos para aumentar o desempenho da reprodução em mamíferos não humanos com uso de hormônio luteinizante recombinante |
CN114404575A (zh) * | 2020-12-07 | 2022-04-29 | 苏州智核生物医药科技有限公司 | 一种重组人促甲状腺素注射液 |
CN117783545A (zh) * | 2023-12-28 | 2024-03-29 | 深圳市新产业生物医学工程股份有限公司 | 经封闭剂封闭的软质材料、容器、液态校准品及检测试剂盒 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4357934A (en) * | 1980-07-23 | 1982-11-09 | The Curators Of The University Of Missouri | Method of treating male infertility |
US4457916A (en) * | 1982-08-31 | 1984-07-03 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same |
IT1206302B (it) * | 1987-06-26 | 1989-04-14 | Serono Cesare Ist Ricerca | Ormone follicolo-stimolante urinario |
US5997856A (en) * | 1988-10-05 | 1999-12-07 | Chiron Corporation | Method and compositions for solubilization and stabilization of polypeptides, especially proteins |
JP3045539B2 (ja) * | 1989-02-21 | 2000-05-29 | ワシントン ユニバーシティ | 改変型生殖ホルモン |
US5338835A (en) * | 1989-02-21 | 1994-08-16 | Washington University | CTP-extended form of FSH |
US5114948A (en) * | 1989-10-19 | 1992-05-19 | Eli Lilly And Company | Stabilized pergolide compositions |
IE64738B1 (en) * | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
US5384132A (en) * | 1990-03-20 | 1995-01-24 | Akzo N.V. | Stabilized gonadotropin containing preparations |
US5272135A (en) * | 1991-03-01 | 1993-12-21 | Chiron Ophthalmics, Inc. | Method for the stabilization of methionine-containing polypeptides |
IT1250075B (it) * | 1991-12-18 | 1995-03-30 | Serono Cesare Ist Ricerca | Composizioni farmaceutiche contenenti gonadotropine. |
CA2133205C (en) * | 1992-04-30 | 2007-04-17 | Robert L. Swift | Stable polypeptide composition |
US5281198A (en) * | 1992-05-04 | 1994-01-25 | Habley Medical Technology Corporation | Pharmaceutical component-mixing delivery assembly |
EP0814841B1 (en) * | 1995-03-21 | 2001-12-05 | Applied Research Systems ARS Holding N.V. | Hcg liquid formulations |
-
1997
- 1997-12-23 IL IL12273297A patent/IL122732A0/xx not_active IP Right Cessation
- 1997-12-23 TW TW086119598A patent/TW518235B/zh not_active IP Right Cessation
-
1998
- 1998-01-06 ZA ZA9883A patent/ZA9883B/xx unknown
- 1998-01-12 ID IDP980030A patent/ID19499A/id unknown
- 1998-01-13 CN CNB981041493A patent/CN1165341C/zh not_active Expired - Lifetime
- 1998-01-13 DE DE69813322T patent/DE69813322T2/de not_active Expired - Lifetime
- 1998-01-13 EP EP98200068A patent/EP0853945B1/en not_active Expired - Lifetime
- 1998-01-13 PT PT98200068T patent/PT853945E/pt unknown
- 1998-01-13 AT AT98200068T patent/ATE237348T1/de active
- 1998-01-13 NZ NZ329572A patent/NZ329572A/xx not_active IP Right Cessation
- 1998-01-13 DE DE122010000011C patent/DE122010000011I1/de active Pending
- 1998-01-13 DK DK98200068T patent/DK0853945T3/da active
- 1998-01-13 ES ES98200068T patent/ES2196474T3/es not_active Expired - Lifetime
- 1998-01-13 EP EP02079923A patent/EP1285665A1/en not_active Withdrawn
- 1998-01-14 KR KR10-1998-0000785A patent/KR100498531B1/ko not_active IP Right Cessation
- 1998-01-14 CA CA002226803A patent/CA2226803A1/en not_active Abandoned
- 1998-01-14 MX MX9800438A patent/MX9800438A/es active IP Right Grant
- 1998-01-14 RU RU98100930/14A patent/RU2203086C2/ru active Protection Beyond IP Right Term
- 1998-01-14 AU AU52059/98A patent/AU736339B2/en not_active Expired
- 1998-01-14 NO NO19980177A patent/NO322509B1/no not_active IP Right Cessation
- 1998-01-14 JP JP00538998A patent/JP4353549B2/ja not_active Expired - Lifetime
- 1998-01-14 AR ARP980100152A patent/AR011410A1/es active IP Right Grant
- 1998-01-14 BR BRPI9800323-2A patent/BR9800323B1/pt not_active IP Right Cessation
- 1998-01-14 HU HU9800056A patent/HU227154B1/hu active Protection Beyond IP Right Term
- 1998-01-14 PL PL98324279A patent/PL190103B1/pl unknown
- 1998-01-15 TR TR1998/00062A patent/TR199800062A2/xx unknown
- 1998-01-15 CZ CZ0013598A patent/CZ297419B6/cs not_active IP Right Cessation
- 1998-04-14 US US09/006,812 patent/US5929028A/en not_active Expired - Lifetime
- 1998-04-22 SA SA98181124A patent/SA98181124B1/ar unknown
- 1998-10-12 HK HK98111196A patent/HK1010150A1/xx not_active IP Right Cessation
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2010
- 2010-02-24 LU LU91655C patent/LU91655I2/fr unknown
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2021
- 2021-01-12 NO NO2021001C patent/NO2021001I1/no unknown
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