NO2010013I2 - Rekombinant FSH-CTP - Google Patents

Rekombinant FSH-CTP

Info

Publication number
NO2010013I2
NO2010013I2 NO2010013C NO2010013C NO2010013I2 NO 2010013 I2 NO2010013 I2 NO 2010013I2 NO 2010013 C NO2010013 C NO 2010013C NO 2010013 C NO2010013 C NO 2010013C NO 2010013 I2 NO2010013 I2 NO 2010013I2
Authority
NO
Norway
Prior art keywords
ctp
recombinant fsh
fsh
recombinant
Prior art date
Application number
NO2010013C
Other languages
English (en)
Other versions
NO2010013I1 (no
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of NO2010013I1 publication Critical patent/NO2010013I1/no
Publication of NO2010013I2 publication Critical patent/NO2010013I2/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO2010013C 1997-01-15 2010-06-07 Rekombinant FSH-CTP NO2010013I2 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97200099 1997-01-15

Publications (2)

Publication Number Publication Date
NO2010013I1 NO2010013I1 (no) 2010-06-07
NO2010013I2 true NO2010013I2 (no) 2015-05-18

Family

ID=8227932

Family Applications (3)

Application Number Title Priority Date Filing Date
NO19980177A NO322509B1 (no) 1997-01-15 1998-01-14 Vaeske gonadotropin-inneholdende formulering, fremgangsmate for fremstilling, samt anvendelse derav.
NO2010013C NO2010013I2 (no) 1997-01-15 2010-06-07 Rekombinant FSH-CTP
NO2021001C NO2021001I1 (no) 1997-01-15 2021-01-12 Korifollitropin alfa - forlenget SPC

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO19980177A NO322509B1 (no) 1997-01-15 1998-01-14 Vaeske gonadotropin-inneholdende formulering, fremgangsmate for fremstilling, samt anvendelse derav.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2021001C NO2021001I1 (no) 1997-01-15 2021-01-12 Korifollitropin alfa - forlenget SPC

Country Status (30)

Country Link
US (1) US5929028A (no)
EP (2) EP0853945B1 (no)
JP (1) JP4353549B2 (no)
KR (1) KR100498531B1 (no)
CN (1) CN1165341C (no)
AR (1) AR011410A1 (no)
AT (1) ATE237348T1 (no)
AU (1) AU736339B2 (no)
BR (1) BR9800323B1 (no)
CA (1) CA2226803A1 (no)
CZ (1) CZ297419B6 (no)
DE (2) DE122010000011I1 (no)
DK (1) DK0853945T3 (no)
ES (1) ES2196474T3 (no)
FR (1) FR10C0024I2 (no)
HK (1) HK1010150A1 (no)
HU (1) HU227154B1 (no)
ID (1) ID19499A (no)
IL (1) IL122732A0 (no)
LU (1) LU91655I2 (no)
MX (1) MX9800438A (no)
NO (3) NO322509B1 (no)
NZ (1) NZ329572A (no)
PL (1) PL190103B1 (no)
PT (1) PT853945E (no)
RU (1) RU2203086C2 (no)
SA (1) SA98181124B1 (no)
TR (1) TR199800062A2 (no)
TW (1) TW518235B (no)
ZA (1) ZA9883B (no)

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US20030166525A1 (en) 1998-07-23 2003-09-04 Hoffmann James Arthur FSH Formulation
JP2000247903A (ja) * 1999-03-01 2000-09-12 Chugai Pharmaceut Co Ltd 長期安定化製剤
JP2007204498A (ja) * 1999-03-01 2007-08-16 Chugai Pharmaceut Co Ltd 長期安定化製剤
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US7256184B2 (en) * 2000-10-16 2007-08-14 Rodriguez Victorio C Treatment of aging disorders in humans
AU2007200662A1 (en) * 2001-08-30 2007-03-08 Kirin-Amgen, Inc. L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
US20030104996A1 (en) 2001-08-30 2003-06-05 Tiansheng Li L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
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US20040248784A1 (en) * 2003-06-03 2004-12-09 Marco Filicori Unitary combinations of FSH and hCG
EP1638595B1 (en) 2003-06-20 2013-03-20 Ares Trading S.A. Freeze-dried fsh / lh formulations
JP4412989B2 (ja) * 2003-12-15 2010-02-10 株式会社日立製作所 複数の記憶システムを有するデータ処理システム
KR100587535B1 (ko) * 2004-02-04 2006-06-08 충남대학교산학협력단 재조합 ｈＦＳＨ 유전자 및 이를 내장하는 발현용 벡터
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US8137677B2 (en) * 2005-10-06 2012-03-20 Allergan, Inc. Non-protein stabilized clostridial toxin pharmaceutical compositions
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US10221228B2 (en) 2006-02-03 2019-03-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US8946155B2 (en) 2006-02-03 2015-02-03 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
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US8450269B2 (en) * 2006-02-03 2013-05-28 Prolor Biotech Ltd. Long-acting growth hormone and methods of producing same
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US20140113860A1 (en) 2006-02-03 2014-04-24 Prolor Biotech Ltd. Long-acting polypeptides and methods of producing and administering same
US9458444B2 (en) 2006-02-03 2016-10-04 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
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US20120265129A1 (en) 2011-04-15 2012-10-18 Neuralight Hd, Llc Methods for Chronic Pain Management and Treatment using HCG
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JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
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BR122020018510B1 (pt) 2012-11-20 2023-03-14 Opko Biologics Ltd Método para aumentar incrementalmente o tamanho hidrodinâmico de um fator de coagulação ativado viia
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US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
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Also Published As

Publication number Publication date
ES2196474T3 (es) 2003-12-16
EP1285665A1 (en) 2003-02-26
CZ13598A3 (cs) 1998-08-12
CA2226803A1 (en) 1998-07-15
HUP9800056A3 (en) 2001-01-29
ZA9883B (en) 1998-07-08
CZ297419B6 (cs) 2006-12-13
DE69813322T2 (de) 2004-02-19
AR011410A1 (es) 2000-08-16
AU5205998A (en) 1998-07-23
NO980177L (no) 1998-07-16
FR10C0024I1 (no) 2010-05-21
KR100498531B1 (ko) 2005-09-30
NO2021001I1 (no) 2021-01-12
DE122010000011I1 (de) 2010-07-08
ID19499A (id) 1998-07-16
US5929028A (en) 1999-07-27
JPH10203997A (ja) 1998-08-04
FR10C0024I2 (fr) 2011-04-01
SA98181124B1 (ar) 2006-07-10
ATE237348T1 (de) 2003-05-15
BR9800323B1 (pt) 2011-04-19
BR9800323A (pt) 1999-06-29
NO2010013I1 (no) 2010-06-07
TW518235B (en) 2003-01-21
AU736339B2 (en) 2001-07-26
NZ329572A (en) 1999-05-28
HU227154B1 (en) 2010-08-30
DK0853945T3 (da) 2003-08-04
CN1165341C (zh) 2004-09-08
PL190103B1 (pl) 2005-10-31
PL324279A1 (en) 1998-07-20
RU2203086C2 (ru) 2003-04-27
EP0853945A1 (en) 1998-07-22
CN1191139A (zh) 1998-08-26
PT853945E (pt) 2003-08-29
NO322509B1 (no) 2006-10-16
HK1010150A1 (en) 1999-06-17
EP0853945B1 (en) 2003-04-16
KR19980070493A (ko) 1998-10-26
IL122732A0 (en) 1998-08-16
HUP9800056A2 (hu) 1998-08-28
HU9800056D0 (en) 1998-03-02
LU91655I2 (fr) 2010-04-26
NO980177D0 (no) 1998-01-14
TR199800062A2 (xx) 1998-08-21
JP4353549B2 (ja) 2009-10-28
MX9800438A (es) 1998-11-30
DE69813322D1 (de) 2003-05-22

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