SE7904118L - Sett att framstella en urokinaskomposition - Google Patents

Sett att framstella en urokinaskomposition

Info

Publication number
SE7904118L
SE7904118L SE7904118A SE7904118A SE7904118L SE 7904118 L SE7904118 L SE 7904118L SE 7904118 A SE7904118 A SE 7904118A SE 7904118 A SE7904118 A SE 7904118A SE 7904118 L SE7904118 L SE 7904118L
Authority
SE
Sweden
Prior art keywords
urokinase
injection
urokina
prepare
composition
Prior art date
Application number
SE7904118A
Other languages
English (en)
Inventor
Y Yamahira
K Fujioka
Y Okuzawa
S Miura
S Sato
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of SE7904118L publication Critical patent/SE7904118L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
SE7904118A 1978-05-12 1979-05-10 Sett att framstella en urokinaskomposition SE7904118L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5682678A JPS54147916A (en) 1978-05-12 1978-05-12 Preparation of urokinase injection

Publications (1)

Publication Number Publication Date
SE7904118L true SE7904118L (sv) 1979-11-13

Family

ID=13038173

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7904118A SE7904118L (sv) 1978-05-12 1979-05-10 Sett att framstella en urokinaskomposition

Country Status (10)

Country Link
US (1) US4244943A (sv)
JP (1) JPS54147916A (sv)
CA (1) CA1115206A (sv)
CH (1) CH641046A5 (sv)
DE (1) DE2917899A1 (sv)
DK (1) DK147812B (sv)
FR (1) FR2425245A1 (sv)
GB (1) GB2021412B (sv)
IT (1) IT7949032A0 (sv)
SE (1) SE7904118L (sv)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5813521A (ja) * 1981-07-16 1983-01-26 Green Cross Corp:The ミエロペルオキシダ−ゼの粉末製剤
US4350659A (en) * 1981-07-30 1982-09-21 Corning Glass Works Stabilization of sensitive biologically active intermediate metabolites such as folic acid derivatives
JPS59139323A (ja) * 1983-01-28 1984-08-10 Green Cross Corp:The ウロキナ−ゼ乾燥製剤
SU1128601A1 (ru) * 1983-05-10 1985-07-15 Всесоюзный кардиологический научный центр АМН СССР Урокиназа,иммобилизированна на фибриногене
JPS6051119A (ja) * 1983-08-30 1985-03-22 Green Cross Corp:The ウロキナ−ゼ乾燥製剤
JPS61111684A (ja) * 1984-11-05 1986-05-29 Terumo Corp 精製されたウロキナ−ゼ複合体の製造方法
JPS61124383A (ja) * 1984-11-16 1986-06-12 Unitika Ltd 固定化線維素溶解活性酵素の安定化法
US4851345A (en) * 1985-01-14 1989-07-25 Terumo Kabushiki Kaisha Fibrinophilic urokinase complex and method for production thereof
KR940003056B1 (ko) * 1985-04-16 1994-04-13 가부시끼가이샤 미도리 쥬우지 우로키나제 전구체를 안정화시키는 방법
JPS61238732A (ja) * 1985-04-16 1986-10-24 Green Cross Corp:The ウロキナーゼ前駆体乾燥製剤
NZ217844A (en) * 1985-10-11 1989-10-27 Sumitomo Pharma A sustained release pharmaceutical composition containing silicone elastomer and an albumin
JP2708749B2 (ja) * 1987-08-10 1998-02-04 エーザイ株式会社 修飾型ｔＰＡ含有注射用組成物
WO1990001334A1 (en) * 1988-08-05 1990-02-22 Codon Formulations for plasminogen activator using aspartate
US4980165A (en) * 1989-01-27 1990-12-25 Genetics Institute, Inc. Pharmaceutical formulations of plasminogen activator proteins
JPH02268681A (ja) * 1989-04-07 1990-11-02 Green Cross Corp:The ウロキナーゼ前駆体の安定化方法及び乾燥製剤
DK0472657T3 (da) * 1989-05-17 1996-06-17 Res Corp Technologies Inc Fremgangsmåde og middel til behandling af trombose i et pattedyr
DE69012675T2 (de) * 1989-06-30 1995-05-04 Ucar Carbon Tech Graphitfolie.
EP2236617A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Methods of terminal sterilization of biofunctional compositions
WO2011134979A2 (en) * 2010-04-27 2011-11-03 Scil Technology Gmbh Stable mia/cd-rap formulation
CN104906054B (zh) * 2015-06-15 2017-08-25 武汉人福药业有限责任公司 一种尿激酶冻干剂的制备方法
CN111450052A (zh) * 2020-04-22 2020-07-28 南京南大药业有限责任公司 一种尿激酶注射液制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE665076A (sv) * 1963-12-23 1965-12-08
JPS5137343B2 (sv) * 1972-12-07 1976-10-15

Also Published As

Publication number Publication date
DK195079A (da) 1979-11-13
IT7949032A0 (it) 1979-05-11
CA1115206A (en) 1981-12-29
DE2917899A1 (de) 1979-11-22
JPS54147916A (en) 1979-11-19
US4244943A (en) 1981-01-13
FR2425245B1 (sv) 1983-03-11
FR2425245A1 (fr) 1979-12-07
CH641046A5 (de) 1984-02-15
DK147812B (da) 1984-12-17
GB2021412A (en) 1979-12-05
GB2021412B (en) 1982-08-25

Similar Documents

Publication Publication Date Title
SE7904118L (sv) Sett att framstella en urokinaskomposition
SE8101065L (sv) Antitrombinberedning
DK372479A (da) Fremgangsmaade til fremstilling af aminosyrederivater
KR840005083A (ko) 항고혈압제로서 유용한 아미노산유도체의 제조방법
ATE24658T1 (de) Verfahren zur herstellung eines molkeproduktes.
ATE866T1 (de) Immunserumglobulin (isg)-praeparate und verfahren zu ihrer herstellung.
DK149111C (da) Analogifremgangsmaade til fremstilling af histidinderivater eller syreadditionssalte deraf
ES416597A1 (es) Procedimiento de preparacion de albumina purificada.
DK162883A (da) N-glucosylerede carboxylsyreamidderivater, fremgangsmaade til fremstilling heraf samt deres anvendelse til paavirkning af organismens egen forsvarsmekanisme
GB1524431A (en) Production of long acting insulin preparations
NO150106C (no) Anvendelse av en n-acyl-alfa-aminosyre som emulgeringsmiddel for fremstilling av emulsjoner
ES483638A0 (es) Un procedimiento para la preparacion de un substituto de la-leche.
DK148183A (da) Fremgangsmaade til fremstilling af imidazolylphenyl-tetrahydropyridaziner
ATE1241T1 (de) Verfahren zur herstellung von 4,5-perfluor-1,3-dioxolanen.
DE3867445D1 (de) Injizierbare loesung des thioctsaeuresalzes mit trometamol und/oder basischen aminosaeuren.
SE7904742L (sv) Stabiliserade mjolkproteinhaltiga kompositioner
PT71408A (de) Verfahren zur herstellung von 1-alkadien-2,4-yl-2-hidroxymethyl-3,4,5-trimydroxypiperidinen mit wirkung uber die kohlehydraten und/oder fettwechsel und von diesen verbindungen enthaltenden pharmazeutischen und/oder tierartzleichen praparaten
SE7609443L (sv) Sett att framstella ett stabilt farmaceutiskt preparat
DK430379A (da) Fremgangsmaade til fremstilling af 2,6-diaminonebulariner eller syreadditionssalte deraf
ATE353T1 (de) Neue alpha-azolyl-alpha-phenylessigsaeurederivate, ihre herstellung, sie enthaltende fungizide, verfahren zur bekaempfung von fungi und zur herstellung von fungiziden.
NO883520L (no) Fremgangsmaate for fremstilling av et injeksjonspreparat.
SE7907986L (sv) Sett att framstella 3alfa,7beta-dihydroxicholansyra
RO81506A (ro) Procedeu pentru prepararea derivatilor acizilor 1,3,4-tiadiazol-2-carboxilici
DK149750C (da) Analogifremgangsmaade til fremstilling af n-alkenylmoranolin-derivater eller farmaceutiske acceptable syreadditionssalte deraf
GB1077249A (en) A new amine and process for its manufacture

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 7904118-2