AP457A - 2,6-Diaminopurine derivatives. - Google Patents
2,6-Diaminopurine derivatives. Download PDFInfo
- Publication number
- AP457A AP457A APAP/P/1994/000613A AP9400613A AP457A AP 457 A AP457 A AP 457A AP 9400613 A AP9400613 A AP 9400613A AP 457 A AP457 A AP 457A
- Authority
- AP
- ARIPO
- Prior art keywords
- amino
- ethyl
- ribofuranuronamide
- purin
- deoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/167—Purine radicals with ribosyl as the saccharide radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939301000A GB9301000D0 (en) | 1993-01-20 | 1993-01-20 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
AP9400613A0 AP9400613A0 (en) | 1994-01-31 |
AP457A true AP457A (en) | 1996-02-01 |
Family
ID=10728948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
APAP/P/1994/000613A AP457A (en) | 1993-01-20 | 1994-01-18 | 2,6-Diaminopurine derivatives. |
Country Status (29)
Country | Link |
---|---|
US (2) | US5925624A (ko) |
EP (1) | EP0680488B1 (ko) |
JP (1) | JP3768232B2 (ko) |
KR (1) | KR960700261A (ko) |
CN (1) | CN1043997C (ko) |
AP (1) | AP457A (ko) |
AT (1) | ATE164849T1 (ko) |
AU (1) | AU679714B2 (ko) |
CA (1) | CA2153688A1 (ko) |
CZ (1) | CZ187995A3 (ko) |
DE (1) | DE69409503T2 (ko) |
DK (1) | DK0680488T3 (ko) |
EC (1) | ECSP941104A (ko) |
ES (1) | ES2117249T3 (ko) |
FI (1) | FI953489A (ko) |
GB (1) | GB9301000D0 (ko) |
HU (1) | HU211914A9 (ko) |
IL (1) | IL108372A (ko) |
IS (1) | IS4121A (ko) |
NO (1) | NO305603B1 (ko) |
NZ (1) | NZ259880A (ko) |
PE (1) | PE54194A1 (ko) |
PL (1) | PL309975A1 (ko) |
RU (1) | RU2129561C1 (ko) |
SI (1) | SI9400021A (ko) |
SK (1) | SK281229B6 (ko) |
TW (1) | TW267168B (ko) |
WO (1) | WO1994017090A1 (ko) |
ZA (1) | ZA94335B (ko) |
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TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
JP3861413B2 (ja) * | 1997-11-05 | 2006-12-20 | ソニー株式会社 | 情報配信システム、情報処理端末装置、携帯端末装置 |
YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
US6413974B1 (en) | 1998-02-26 | 2002-07-02 | Aventis Pharmaceuticals Inc. | 6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines |
US6479487B1 (en) | 1998-02-26 | 2002-11-12 | Aventis Pharmaceuticals Inc. | 6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines |
HUP0100931A3 (en) * | 1998-02-26 | 2002-08-28 | Aventis Pharma Inc | 6,9-disubstituted 2-[trans-(-aminocyclohexyl)amino]purines and pharmaceutical compositions containing them |
US6686366B1 (en) | 1998-06-02 | 2004-02-03 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
US6878716B1 (en) | 1998-06-02 | 2005-04-12 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptor and uses thereof |
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GB9813535D0 (en) * | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
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GB9813565D0 (en) * | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
HUP0103025A3 (en) * | 1998-06-23 | 2002-04-29 | Glaxo Group Ltd | A2a agonist 2-(purin-9-yl)tetrahydrofuran-3,4-diol derivatives, medicaments containing the same, process for producing them and the useful intermediates |
GB9813554D0 (en) * | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
US7160890B2 (en) | 1999-12-02 | 2007-01-09 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
US6664252B2 (en) | 1999-12-02 | 2003-12-16 | Osi Pharmaceuticals, Inc. | 4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof |
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US5219840A (en) * | 1987-04-06 | 1993-06-15 | Sandoz Ltd. | Antihypertensive 9-(2,N6 -disubstituted adenyl) ribofuranuronic acid derivatives |
LU87181A1 (fr) * | 1987-04-06 | 1988-11-17 | Sandoz Sa | Nouveaux derives de l'acide furannuronique,leur preparation et leur utilisation comme medicaments |
WO1989008658A1 (en) * | 1988-03-16 | 1989-09-21 | Scripps Clinic And Research Foundation | Substituted adenine derivatives useful as therapeutic agents |
JPH0725785B2 (ja) * | 1989-01-11 | 1995-03-22 | 日本臓器製薬株式会社 | アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物 |
DE3924424A1 (de) * | 1989-07-24 | 1991-01-31 | Boehringer Mannheim Gmbh | Nucleosid-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel sowie deren verwendung bei der nucleinsaeure-sequenzierung |
PT95628A (pt) * | 1989-10-19 | 1991-09-30 | Searle & Co | Metodo de tratamento de perturbacoes de mobilidade gastrointestinal com composto de adenosina |
US5459255A (en) * | 1990-01-11 | 1995-10-17 | Isis Pharmaceuticals, Inc. | N-2 substituted purines |
DE4025879A1 (de) * | 1990-08-16 | 1992-02-20 | Sandoz Ag | Neue adenosin derivate, deren herstellung und verwendung |
FR2687678B1 (fr) * | 1992-01-31 | 1995-03-31 | Union Pharma Scient Appl | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
ATE206432T1 (de) * | 1993-07-13 | 2001-10-15 | Nasa | A3 -adenosin -rezeptor agonisten |
-
1993
- 1993-01-20 GB GB939301000A patent/GB9301000D0/en active Pending
-
1994
- 1994-01-14 IS IS4121A patent/IS4121A/is unknown
- 1994-01-18 RU RU95122754A patent/RU2129561C1/ru active
- 1994-01-18 PL PL94309975A patent/PL309975A1/xx unknown
- 1994-01-18 AU AU58851/94A patent/AU679714B2/en not_active Ceased
- 1994-01-18 CA CA002153688A patent/CA2153688A1/en not_active Abandoned
- 1994-01-18 DK DK94905100T patent/DK0680488T3/da active
- 1994-01-18 WO PCT/EP1994/000145 patent/WO1994017090A1/en not_active Application Discontinuation
- 1994-01-18 CN CN94191527A patent/CN1043997C/zh not_active Expired - Fee Related
- 1994-01-18 SK SK918-95A patent/SK281229B6/sk unknown
- 1994-01-18 JP JP51665294A patent/JP3768232B2/ja not_active Expired - Fee Related
- 1994-01-18 KR KR1019950702963A patent/KR960700261A/ko active IP Right Grant
- 1994-01-18 AP APAP/P/1994/000613A patent/AP457A/en active
- 1994-01-18 NZ NZ259880A patent/NZ259880A/en unknown
- 1994-01-18 US US08/446,727 patent/US5925624A/en not_active Expired - Fee Related
- 1994-01-18 DE DE69409503T patent/DE69409503T2/de not_active Expired - Lifetime
- 1994-01-18 ZA ZA94335A patent/ZA94335B/xx unknown
- 1994-01-18 AT AT94905100T patent/ATE164849T1/de not_active IP Right Cessation
- 1994-01-18 EP EP94905100A patent/EP0680488B1/en not_active Expired - Lifetime
- 1994-01-18 ES ES94905100T patent/ES2117249T3/es not_active Expired - Lifetime
- 1994-01-18 CZ CZ951879A patent/CZ187995A3/cs unknown
- 1994-01-19 IL IL108372A patent/IL108372A/en not_active IP Right Cessation
- 1994-01-19 SI SI9400021A patent/SI9400021A/sl unknown
- 1994-05-30 TW TW083104895A patent/TW267168B/zh active
- 1994-06-14 EC EC1994001104A patent/ECSP941104A/es unknown
- 1994-06-15 PE PE1994244634A patent/PE54194A1/es not_active Application Discontinuation
-
1995
- 1995-06-28 HU HU95P/P00514P patent/HU211914A9/hu unknown
- 1995-07-19 NO NO952872A patent/NO305603B1/no not_active IP Right Cessation
- 1995-07-19 FI FI953489A patent/FI953489A/fi unknown
-
1997
- 1997-09-22 US US08/934,540 patent/US5889178A/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0222330A2 (en) * | 1985-11-06 | 1987-05-20 | Warner-Lambert Company | N6-Substituted-5'-oxidized adenosine analogs |
EP0277917A2 (en) * | 1987-02-04 | 1988-08-10 | Ciba-Geigy Ag | Certain adenosine 5'-carboxamide derivatives |
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