ZW13185A1 - Heterocyclic derivatives - Google Patents

Heterocyclic derivatives

Info

Publication number
ZW13185A1
ZW13185A1 ZW131/85A ZW13185A ZW13185A1 ZW 13185 A1 ZW13185 A1 ZW 13185A1 ZW 131/85 A ZW131/85 A ZW 131/85A ZW 13185 A ZW13185 A ZW 13185A ZW 13185 A1 ZW13185 A1 ZW 13185A1
Authority
ZW
Zimbabwe
Prior art keywords
heterocyclic derivatives
heterocyclic
derivatives
Prior art date
Application number
ZW131/85A
Other languages
English (en)
Inventor
Semeraro Claudio
Pierracioli Daniele
David Borthwick Allan
Micheli Dino
Gaviraghi Giovanni
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22383/84A external-priority patent/IT1175620B/it
Priority claimed from IT21460/85A external-priority patent/IT1187678B/it
Application filed by Glaxo Spa filed Critical Glaxo Spa
Publication of ZW13185A1 publication Critical patent/ZW13185A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B2205/00—Fibre drawing or extruding details
    • C03B2205/44—Monotoring or regulating the preform feed rate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZW131/85A 1984-08-22 1985-08-20 Heterocyclic derivatives ZW13185A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22383/84A IT1175620B (it) 1984-08-22 1984-08-22 Derivati piridinici
IT21460/85A IT1187678B (it) 1985-07-05 1985-07-05 Procedimento di preparazione di derivati eterociclici

Publications (1)

Publication Number Publication Date
ZW13185A1 true ZW13185A1 (en) 1986-03-19

Family

ID=26327905

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW131/85A ZW13185A1 (en) 1984-08-22 1985-08-20 Heterocyclic derivatives

Country Status (33)

Country Link
US (2) US4801599A (instruction)
JP (2) JPS6193162A (instruction)
KR (1) KR920004482B1 (instruction)
AT (1) AT394042B (instruction)
AU (1) AU578724B2 (instruction)
BE (1) BE903103A (instruction)
BG (1) BG60409B2 (instruction)
CA (1) CA1268180A (instruction)
CH (1) CH666684A5 (instruction)
CS (1) CS403091A3 (instruction)
CY (1) CY1494A (instruction)
DE (1) DE3529997C2 (instruction)
DK (1) DK165949C (instruction)
ES (5) ES8703839A1 (instruction)
FI (1) FI81568C (instruction)
FR (1) FR2569402B1 (instruction)
GB (1) GB2164336B (instruction)
GR (1) GR852016B (instruction)
HK (1) HK52990A (instruction)
HU (1) HU196754B (instruction)
IE (1) IE58486B1 (instruction)
LU (2) LU88267I2 (instruction)
MX (1) MX159974A (instruction)
NL (2) NL193065C (instruction)
NO (2) NO167142C (instruction)
NZ (1) NZ212895A (instruction)
PH (1) PH22014A (instruction)
PT (1) PT81000B (instruction)
SA (1) SA91120277B1 (instruction)
SE (1) SE459920B (instruction)
SG (1) SG40889G (instruction)
SK (1) SK278327B6 (instruction)
ZW (1) ZW13185A1 (instruction)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
DE3675747D1 (de) * 1985-08-21 1991-01-03 Glaxo Spa 1,4-dihydropyridinverbindungen und ihre herstellung und pharmazeutische formulierung.
AT394043B (de) * 1985-08-21 1992-01-27 Glaxo Spa Verfahren zur herstellung von neuen dihydropyridinderivaten
IT1204460B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1204462B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1204461B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1233370B (it) * 1988-11-21 1992-03-27 Glaxo Spa Procedimento di preparazione di derivati diidropipiridinici utili nel trattamento di disturbi cardiovascolari
DE69030982T2 (de) 1989-04-27 1997-11-13 Canon Kk Optisches Aufzeichnungsmedium und Verfahren zu seiner Herstellung
US5177202A (en) * 1990-10-09 1993-01-05 Merck & Co., Inc. 2-phenanthrenyl-carbapenems
US5196529A (en) * 1990-10-09 1993-03-23 Merck & Co., Inc. 2-phenanthrenyl carbapenem intermediates
US5132421A (en) * 1990-10-09 1992-07-21 Merck & Co., Inc. 2-naphthyl-carbapenem intermediates
US5132422A (en) * 1990-10-09 1992-07-21 Merck & Co., Inc. 2-naphthyl-carbapenem intermediates
US5144028A (en) * 1990-10-09 1992-09-01 Merck & Co., Inc. 2-(9-fluorenonyl)-carbapenem intermediates
US5356889A (en) * 1990-08-01 1994-10-18 Merck & Co., Inc. 2-(9-fluorenonyl)-carbapenem intermediates
US5208329A (en) * 1990-10-09 1993-05-04 Merck & Co., Inc. 2-biphenyl carbapenem intermediates
IT1244728B (it) * 1991-02-13 1994-08-08 Glaxo Spa Impiego medicamentoso di derivati diidropiridinici
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
AU1042199A (en) * 1998-11-06 2000-05-29 Boehringer Ingelheim International Gmbh Antihypertensive medicaments containing lacidipine and telmisartan
HRP20050163A2 (en) 2002-08-19 2005-06-30 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
EP1658283A2 (en) * 2003-05-30 2006-05-24 Ranbaxy Laboratories, Ltd. Substituted pyrrole derivatives and their use as hmg-co inhibitors
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
AU2005269465A1 (en) * 2004-07-26 2006-02-09 Cotherix, Inc. Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation
EP1868577A4 (en) 2005-04-15 2009-12-09 Reddys Lab Inc Dr Lacidipine PARTICLE
US20070043088A1 (en) * 2005-08-16 2007-02-22 Eswaraiah Sajja Process for preparing lacidipine
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
ATE551059T1 (de) * 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
AU2006313430B2 (en) * 2005-11-08 2012-09-06 Ranbaxy Laboratories Limited Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
WO2008020314A2 (en) * 2006-03-14 2008-02-21 Ranbaxy Laboratories Limited Statin stabilizing dosage formulations
MX2009000439A (es) * 2006-07-14 2009-02-04 Ranbaxy Lab Ltd Formas polimorficas de un inhibidor de hmg-coa reductasa y usos de las mismas.
US20080089947A1 (en) * 2006-08-18 2008-04-17 Knox Clayton D Calcium Influx Inhibitors in the Treatment of Ischemia
US8404896B2 (en) 2006-12-01 2013-03-26 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
LT2705839T (lt) 2012-09-10 2018-06-11 Rivopharm Sa Farmacinė kompozicija, apimanti lacidipiną ir jos gavimo būdas
CA2909442A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
KR20210116548A (ko) 2019-01-18 2021-09-27 아스트라제네카 아베 Pcsk9 억제제 및 이의 이용 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455945A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines
DE2228363A1 (de) * 1972-06-10 1974-01-03 Bayer Ag 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
DE3018259A1 (de) * 1980-05-13 1981-11-19 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
AT394042B (de) 1992-01-27
IE58486B1 (en) 1993-09-22
CH666684A5 (de) 1988-08-15
ES8707931A1 (es) 1987-09-01
HK52990A (en) 1990-07-20
SE8503888D0 (sv) 1985-08-20
SK278327B6 (en) 1996-11-06
KR920004482B1 (ko) 1992-06-05
LU86047A1 (fr) 1986-02-28
ES552050A0 (es) 1987-09-01
FI853206A0 (fi) 1985-08-21
IE852054L (en) 1986-02-22
FR2569402B1 (fr) 1989-09-22
DK165949B (da) 1993-02-15
LU88267I2 (instruction) 1994-02-03
PH22014A (en) 1988-05-02
NZ212895A (en) 1988-07-28
ES8703839A1 (es) 1987-03-01
NO1999007I1 (no) 1999-04-23
ES552051A0 (es) 1987-09-01
FR2569402A1 (fr) 1986-02-28
NO167142C (no) 1991-10-09
ES8707932A1 (es) 1987-09-01
NO853293L (no) 1986-02-24
NL193065C (nl) 1998-09-08
CY1494A (en) 1990-02-16
NL980037I2 (nl) 1999-03-01
DK165949C (da) 1993-07-05
SG40889G (en) 1989-12-22
ES552048A0 (es) 1987-09-01
JPS6479152A (en) 1989-03-24
ATA245485A (de) 1991-07-15
SA91120277B1 (ar) 2006-05-15
CA1268180A (en) 1990-04-24
AU4657685A (en) 1986-02-27
NL193065B (nl) 1998-05-06
US4801599A (en) 1989-01-31
AU578724B2 (en) 1988-11-03
JPH0550506B2 (instruction) 1993-07-29
GB2164336B (en) 1988-06-08
GR852016B (instruction) 1985-12-19
CS403091A3 (en) 1992-06-17
JPH0686430B2 (ja) 1994-11-02
PT81000A (en) 1985-09-01
BE903103A (fr) 1986-02-24
FI81568C (fi) 1990-11-12
SE459920B (sv) 1989-08-21
ES552049A0 (es) 1988-07-01
GB8520924D0 (en) 1985-09-25
HUT40625A (en) 1987-01-28
FI853206L (fi) 1986-02-23
ES546324A0 (es) 1987-03-01
KR870002073A (ko) 1987-03-28
DK378085D0 (da) 1985-08-20
NO167142B (no) 1991-07-01
US5011848A (en) 1991-04-30
BG60409B2 (bg) 1995-02-28
JPS6193162A (ja) 1986-05-12
DK378085A (da) 1986-02-23
FI81568B (fi) 1990-07-31
GB2164336A (en) 1986-03-19
ES8707930A1 (es) 1987-09-01
SE8503888L (sv) 1986-02-23
NL980037I1 (nl) 1999-02-01
DE3529997C2 (de) 1996-01-18
DE3529997A1 (de) 1986-03-06
NL8502296A (nl) 1986-03-17
MX159974A (es) 1989-10-17
PT81000B (pt) 1988-03-03
HU196754B (en) 1989-01-30
ES8802497A1 (es) 1988-07-01

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