ZW13185A1 - Heterocyclic derivatives - Google Patents

Heterocyclic derivatives

Info

Publication number
ZW13185A1
ZW13185A1 ZW131/85A ZW13185A ZW13185A1 ZW 13185 A1 ZW13185 A1 ZW 13185A1 ZW 131/85 A ZW131/85 A ZW 131/85A ZW 13185 A ZW13185 A ZW 13185A ZW 13185 A1 ZW13185 A1 ZW 13185A1
Authority
ZW
Zimbabwe
Prior art keywords
heterocyclic derivatives
heterocyclic
derivatives
Prior art date
Application number
ZW131/85A
Other languages
English (en)
Inventor
Semeraro Claudio
Pierracioli Daniele
David Borthwick Allan
Micheli Dino
Gaviraghi Giovanni
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22383/84A external-priority patent/IT1175620B/it
Priority claimed from IT21460/85A external-priority patent/IT1187678B/it
Application filed by Glaxo Spa filed Critical Glaxo Spa
Publication of ZW13185A1 publication Critical patent/ZW13185A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B2205/00—Fibre drawing or extruding details
    • C03B2205/44—Monotoring or regulating the preform feed rate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZW131/85A 1984-08-22 1985-08-20 Heterocyclic derivatives ZW13185A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22383/84A IT1175620B (it) 1984-08-22 1984-08-22 Derivati piridinici
IT21460/85A IT1187678B (it) 1985-07-05 1985-07-05 Procedimento di preparazione di derivati eterociclici

Publications (1)

Publication Number Publication Date
ZW13185A1 true ZW13185A1 (en) 1986-03-19

Family

ID=26327905

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW131/85A ZW13185A1 (en) 1984-08-22 1985-08-20 Heterocyclic derivatives

Country Status (33)

Country Link
US (2) US4801599A (OSRAM)
JP (2) JPS6193162A (OSRAM)
KR (1) KR920004482B1 (OSRAM)
AT (1) AT394042B (OSRAM)
AU (1) AU578724B2 (OSRAM)
BE (1) BE903103A (OSRAM)
BG (1) BG60409B2 (OSRAM)
CA (1) CA1268180A (OSRAM)
CH (1) CH666684A5 (OSRAM)
CS (1) CS403091A3 (OSRAM)
CY (1) CY1494A (OSRAM)
DE (1) DE3529997C2 (OSRAM)
DK (1) DK165949C (OSRAM)
ES (5) ES8703839A1 (OSRAM)
FI (1) FI81568C (OSRAM)
FR (1) FR2569402B1 (OSRAM)
GB (1) GB2164336B (OSRAM)
GR (1) GR852016B (OSRAM)
HK (1) HK52990A (OSRAM)
HU (1) HU196754B (OSRAM)
IE (1) IE58486B1 (OSRAM)
LU (2) LU86047A1 (OSRAM)
MX (1) MX159974A (OSRAM)
NL (2) NL193065C (OSRAM)
NO (2) NO167142C (OSRAM)
NZ (1) NZ212895A (OSRAM)
PH (1) PH22014A (OSRAM)
PT (1) PT81000B (OSRAM)
SA (1) SA91120277B1 (OSRAM)
SE (1) SE459920B (OSRAM)
SG (1) SG40889G (OSRAM)
SK (1) SK278327B6 (OSRAM)
ZW (1) ZW13185A1 (OSRAM)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
CA1337295C (en) * 1985-08-21 1995-10-10 Claudio Semeraro Dihydropyridine derivatives and their preparation and pharmaceutical formulation
EP0226271B1 (en) * 1985-08-21 1990-11-22 GLAXO S.p.A. 1,4-dihydropyridine compounds and their preparation and pharmaceutical formulation
IT1204461B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1204462B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1204460B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1233370B (it) * 1988-11-21 1992-03-27 Glaxo Spa Procedimento di preparazione di derivati diidropipiridinici utili nel trattamento di disturbi cardiovascolari
EP0395369B1 (en) 1989-04-27 1997-07-02 Canon Inc. Optical recording medium and process for production thereof
US5177202A (en) * 1990-10-09 1993-01-05 Merck & Co., Inc. 2-phenanthrenyl-carbapenems
US5196529A (en) * 1990-10-09 1993-03-23 Merck & Co., Inc. 2-phenanthrenyl carbapenem intermediates
US5132422A (en) * 1990-10-09 1992-07-21 Merck & Co., Inc. 2-naphthyl-carbapenem intermediates
US5132421A (en) * 1990-10-09 1992-07-21 Merck & Co., Inc. 2-naphthyl-carbapenem intermediates
US5356889A (en) * 1990-08-01 1994-10-18 Merck & Co., Inc. 2-(9-fluorenonyl)-carbapenem intermediates
US5144028A (en) * 1990-10-09 1992-09-01 Merck & Co., Inc. 2-(9-fluorenonyl)-carbapenem intermediates
US5208329A (en) * 1990-10-09 1993-05-04 Merck & Co., Inc. 2-biphenyl carbapenem intermediates
IT1244728B (it) * 1991-02-13 1994-08-08 Glaxo Spa Impiego medicamentoso di derivati diidropiridinici
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
AU1042199A (en) * 1998-11-06 2000-05-29 Boehringer Ingelheim International Gmbh Antihypertensive medicaments containing lacidipine and telmisartan
RS20050106A (en) 2002-08-19 2007-11-15 Pfizer Products Inc., Combination therapy for hyperproliferative diseases
AU2004242777B2 (en) * 2003-05-30 2011-05-12 Ranbaxy Laboratories Limited Substituted pyrrole derivatives and their use as HMG-Co inhibitors
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
WO2006014930A2 (en) * 2004-07-26 2006-02-09 Cotherix, Inc. Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation
EP1868577A4 (en) 2005-04-15 2009-12-09 Reddys Lab Inc Dr Lacidipine PARTICLE
US20070043088A1 (en) * 2005-08-16 2007-02-22 Eswaraiah Sajja Process for preparing lacidipine
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
ATE551059T1 (de) 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
KR101329112B1 (ko) * 2005-11-08 2013-11-14 랜박시 래보러터리스 리미티드 (3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
WO2008020314A2 (en) * 2006-03-14 2008-02-21 Ranbaxy Laboratories Limited Statin stabilizing dosage formulations
BRPI0714361A2 (pt) * 2006-07-14 2013-03-26 Ranbaxy Lab Ltd polimorfo cristalino, composiÇço farmacÊutica contendo o mesmo, mÉtodo para sua preparaÇço e mÉtodo de tratamento
US20080089947A1 (en) * 2006-08-18 2008-04-17 Knox Clayton D Calcium Influx Inhibitors in the Treatment of Ischemia
EP2094643B1 (en) 2006-12-01 2012-02-29 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US8883844B2 (en) 2010-09-24 2014-11-11 Nitrogenix Inc. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
LT2705839T (lt) 2012-09-10 2018-06-11 Rivopharm Sa Farmacinė kompozicija, apimanti lacidipiną ir jos gavimo būdas
RU2618628C1 (ru) 2013-04-17 2017-05-05 Пфайзер Инк. Производные N-пиперидин-3-илбензамида для лечения сердечно-сосудистых заболеваний
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN119119023A (zh) 2019-01-18 2024-12-13 阿斯利康(瑞典)有限公司 Pcsk9抑制剂及其使用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455945A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines
DE2228363A1 (de) * 1972-06-10 1974-01-03 Bayer Ag 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
DE3018259A1 (de) * 1980-05-13 1981-11-19 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
US4801599A (en) 1989-01-31
NO167142C (no) 1991-10-09
ES8707931A1 (es) 1987-09-01
DK378085A (da) 1986-02-23
LU88267I2 (OSRAM) 1994-02-03
IE58486B1 (en) 1993-09-22
DE3529997A1 (de) 1986-03-06
SE459920B (sv) 1989-08-21
ES8707930A1 (es) 1987-09-01
NZ212895A (en) 1988-07-28
NO853293L (no) 1986-02-24
CY1494A (en) 1990-02-16
DK378085D0 (da) 1985-08-20
PT81000A (en) 1985-09-01
GB2164336A (en) 1986-03-19
KR920004482B1 (ko) 1992-06-05
DE3529997C2 (de) 1996-01-18
ES546324A0 (es) 1987-03-01
HUT40625A (en) 1987-01-28
FI853206L (fi) 1986-02-23
JPS6479152A (en) 1989-03-24
LU86047A1 (fr) 1986-02-28
DK165949B (da) 1993-02-15
SK278327B6 (en) 1996-11-06
NL980037I1 (nl) 1999-02-01
CA1268180A (en) 1990-04-24
BG60409B2 (bg) 1995-02-28
FI81568C (fi) 1990-11-12
SE8503888D0 (sv) 1985-08-20
MX159974A (es) 1989-10-17
NL193065B (nl) 1998-05-06
SA91120277B1 (ar) 2006-05-15
NL193065C (nl) 1998-09-08
US5011848A (en) 1991-04-30
NO167142B (no) 1991-07-01
HU196754B (en) 1989-01-30
ES8802497A1 (es) 1988-07-01
ES552051A0 (es) 1987-09-01
ES552050A0 (es) 1987-09-01
IE852054L (en) 1986-02-22
AT394042B (de) 1992-01-27
AU4657685A (en) 1986-02-27
AU578724B2 (en) 1988-11-03
JPH0686430B2 (ja) 1994-11-02
PH22014A (en) 1988-05-02
SE8503888L (sv) 1986-02-23
FI81568B (fi) 1990-07-31
DK165949C (da) 1993-07-05
SG40889G (en) 1989-12-22
ES552048A0 (es) 1987-09-01
PT81000B (pt) 1988-03-03
NL980037I2 (nl) 1999-03-01
JPS6193162A (ja) 1986-05-12
HK52990A (en) 1990-07-20
JPH0550506B2 (OSRAM) 1993-07-29
GB2164336B (en) 1988-06-08
GB8520924D0 (en) 1985-09-25
ES8703839A1 (es) 1987-03-01
NO1999007I1 (no) 1999-04-23
NL8502296A (nl) 1986-03-17
KR870002073A (ko) 1987-03-28
BE903103A (fr) 1986-02-24
ATA245485A (de) 1991-07-15
CS403091A3 (en) 1992-06-17
FR2569402A1 (fr) 1986-02-28
FR2569402B1 (fr) 1989-09-22
CH666684A5 (de) 1988-08-15
GR852016B (OSRAM) 1985-12-19
ES8707932A1 (es) 1987-09-01
ES552049A0 (es) 1988-07-01
FI853206A0 (fi) 1985-08-21

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