ZA941767B - Polypeptide bombesin antagonists. - Google Patents

Polypeptide bombesin antagonists.

Info

Publication number
ZA941767B
ZA941767B ZA941767A ZA941767A ZA941767B ZA 941767 B ZA941767 B ZA 941767B ZA 941767 A ZA941767 A ZA 941767A ZA 941767 A ZA941767 A ZA 941767A ZA 941767 B ZA941767 B ZA 941767B
Authority
ZA
South Africa
Prior art keywords
phenyl
alkyl
hydrogen
moiety
10alkyl
Prior art date
Application number
ZA941767A
Other languages
English (en)
Inventor
Andrew Victor Schally
Ren Zhi Cai
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane filed Critical Univ Tulane
Publication of ZA941767B publication Critical patent/ZA941767B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086Bombesin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA941767A 1993-03-15 1994-03-14 Polypeptide bombesin antagonists. ZA941767B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/031,325 US5369094A (en) 1990-11-29 1993-03-15 Polypeptide bombesin antagonists

Publications (1)

Publication Number Publication Date
ZA941767B true ZA941767B (en) 1994-10-06

Family

ID=21858823

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA941767A ZA941767B (en) 1993-03-15 1994-03-14 Polypeptide bombesin antagonists.

Country Status (27)

Country Link
US (1) US5369094A (sl)
EP (1) EP0646127B1 (sl)
JP (1) JP3838656B2 (sl)
KR (1) KR100306506B1 (sl)
AT (1) ATE167874T1 (sl)
AU (1) AU666270B2 (sl)
BR (1) BR9404341A (sl)
CA (1) CA2135787C (sl)
CZ (1) CZ286750B6 (sl)
DE (1) DE69411342T2 (sl)
DK (1) DK0646127T3 (sl)
EE (1) EE03180B1 (sl)
ES (1) ES2120615T3 (sl)
FI (1) FI945378A (sl)
HR (1) HRP940164B1 (sl)
HU (1) HU218288B (sl)
IL (2) IL108851A (sl)
NO (1) NO313418B1 (sl)
NZ (2) NZ299913A (sl)
PL (1) PL180372B1 (sl)
RU (1) RU2114118C1 (sl)
SI (1) SI9420001B (sl)
SK (1) SK282267B6 (sl)
TW (1) TW325478B (sl)
UA (1) UA34456C2 (sl)
WO (1) WO1994021674A1 (sl)
ZA (1) ZA941767B (sl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723578A (en) * 1987-09-24 1998-03-03 The Administrators Of Tulane Educational Fund Peptide analogs of bombesin
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US5650395A (en) * 1995-03-13 1997-07-22 Hurel; Steven Treatment of pulmonary hypertension
US6989371B1 (en) 1996-08-16 2006-01-24 Dabur Research Foundation Bombesin analogs for treatment of cancer
US6200546B1 (en) 1997-04-22 2001-03-13 The Curators Of The University Of Missouri Gastrin receptor-avid peptide conjugates
MXPA03003481A (es) * 2000-11-17 2004-09-10 Warner Lambert Co Tratamiento de disfuncion sexual utilizando antagonista de bombesina.
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) * 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
JP4610345B2 (ja) * 2003-01-13 2011-01-12 ブラッコ・イメージング・ソシエタ・ペル・アチオニ 医薬品化合物のための改善されたリンカー
US20060239923A1 (en) * 2003-01-13 2006-10-26 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7611692B2 (en) * 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US8420050B2 (en) * 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7922998B2 (en) * 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
EP2161037A3 (en) 2003-04-22 2010-05-26 Ipsen Pharma Camptothecin-Somatostatin conjugates
US7795385B2 (en) * 2004-12-17 2010-09-14 Bexar Global, Inc. Use of bombesin/gastrin-releasing peptide antagonists for the treatment of inflammatory conditions, acute lung injury and bipolar disorder
FR2918566B1 (fr) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
EP2100900A1 (en) * 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
EP2198878A1 (en) * 2008-12-18 2010-06-23 University Of Miami Polypeptide bombesin antagonists
US8829196B2 (en) 2009-10-07 2014-09-09 Merck Sharp & Dohme Corp. TRPA1 antagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド
US5162497A (en) * 1987-09-24 1992-11-10 The Administrators Of The Tulane Educational Fund Bradykinin analogs with non-peptide bond
US5084555A (en) * 1989-08-21 1992-01-28 The Administrators Of The Tulane Educational Fund An octapeptide bombesin analog
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
MC2144A1 (fr) * 1988-10-14 1992-02-19 Univ Tulane Peptides therapeutiques
US5217955A (en) * 1989-09-15 1993-06-08 Biomeasure, Inc. Treatment of cancer with peptide analog of bombesin, grp, litorin or neuromedin
US5244883A (en) * 1990-11-29 1993-09-14 The Administrators Of The Tulane Educational Fund Nonapeptide bombesin antagonists

Also Published As

Publication number Publication date
NO944293D0 (no) 1994-11-10
PL306209A1 (en) 1995-03-06
ES2120615T3 (es) 1998-11-01
JP3838656B2 (ja) 2006-10-25
DE69411342D1 (de) 1998-08-06
FI945378A0 (fi) 1994-11-15
IL108851A (en) 2003-05-29
EE03180B1 (et) 1999-04-15
KR100306506B1 (ko) 2001-12-01
SK282267B6 (sk) 2001-12-03
AU6444694A (en) 1994-10-11
NO944293L (no) 1995-01-02
RU94046091A (ru) 1996-09-27
ATE167874T1 (de) 1998-07-15
AU666270B2 (en) 1996-02-01
CA2135787C (en) 2008-08-12
WO1994021674A1 (en) 1994-09-29
TW325478B (en) 1998-01-21
JPH07507330A (ja) 1995-08-10
EP0646127A1 (en) 1995-04-05
DK0646127T3 (da) 1999-04-12
HU218288B (en) 2000-07-28
KR950701646A (ko) 1995-04-28
HRP940164B1 (en) 2000-02-29
NZ299913A (en) 2000-07-28
IL154995A0 (en) 2003-10-31
CZ280794A3 (en) 1995-07-12
CZ286750B6 (en) 2000-06-14
NO313418B1 (no) 2002-09-30
EP0646127B1 (en) 1998-07-01
US5369094A (en) 1994-11-29
PL180372B1 (pl) 2001-01-31
HUT69727A (en) 1995-09-28
BR9404341A (pt) 1999-08-31
HRP940164A2 (en) 1996-08-31
NZ263668A (en) 1997-06-24
RU2114118C1 (ru) 1998-06-27
SK136494A3 (en) 1995-08-09
UA34456C2 (uk) 2001-03-15
SI9420001A (en) 1995-08-31
FI945378A (fi) 1994-11-15
DE69411342T2 (de) 1998-11-19
IL108851A0 (en) 1994-06-24
SI9420001B (sl) 1999-08-31
CA2135787A1 (en) 1994-09-29

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