SK282267B6 - Bombezínu antagonistický peptid, farmaceutický prostriedok s jeho obsahom a jeho použitie - Google Patents

Bombezínu antagonistický peptid, farmaceutický prostriedok s jeho obsahom a jeho použitie Download PDF

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Publication number
SK282267B6
SK282267B6 SK1364-94A SK136494A SK282267B6 SK 282267 B6 SK282267 B6 SK 282267B6 SK 136494 A SK136494 A SK 136494A SK 282267 B6 SK282267 B6 SK 282267B6
Authority
SK
Slovakia
Prior art keywords
alkyl
leu
peptide
phenyl
trp
Prior art date
Application number
SK1364-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK136494A3 (en
Inventor
Andrew V. Schally
Ren Zhi Cai
Original Assignee
The Administrators Of The Tulane Educational Fund
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Administrators Of The Tulane Educational Fund filed Critical The Administrators Of The Tulane Educational Fund
Publication of SK136494A3 publication Critical patent/SK136494A3/sk
Publication of SK282267B6 publication Critical patent/SK282267B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086Bombesin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SK1364-94A 1993-03-15 1994-03-07 Bombezínu antagonistický peptid, farmaceutický prostriedok s jeho obsahom a jeho použitie SK282267B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/031,325 US5369094A (en) 1990-11-29 1993-03-15 Polypeptide bombesin antagonists
PCT/US1994/002511 WO1994021674A1 (en) 1993-03-15 1994-03-07 Polypeptide bombesin antagonists

Publications (2)

Publication Number Publication Date
SK136494A3 SK136494A3 (en) 1995-08-09
SK282267B6 true SK282267B6 (sk) 2001-12-03

Family

ID=21858823

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1364-94A SK282267B6 (sk) 1993-03-15 1994-03-07 Bombezínu antagonistický peptid, farmaceutický prostriedok s jeho obsahom a jeho použitie

Country Status (27)

Country Link
US (1) US5369094A (sl)
EP (1) EP0646127B1 (sl)
JP (1) JP3838656B2 (sl)
KR (1) KR100306506B1 (sl)
AT (1) ATE167874T1 (sl)
AU (1) AU666270B2 (sl)
BR (1) BR9404341A (sl)
CA (1) CA2135787C (sl)
CZ (1) CZ286750B6 (sl)
DE (1) DE69411342T2 (sl)
DK (1) DK0646127T3 (sl)
EE (1) EE03180B1 (sl)
ES (1) ES2120615T3 (sl)
FI (1) FI945378A0 (sl)
HR (1) HRP940164B1 (sl)
HU (1) HU218288B (sl)
IL (2) IL108851A (sl)
NO (1) NO313418B1 (sl)
NZ (2) NZ263668A (sl)
PL (1) PL180372B1 (sl)
RU (1) RU2114118C1 (sl)
SI (1) SI9420001B (sl)
SK (1) SK282267B6 (sl)
TW (1) TW325478B (sl)
UA (1) UA34456C2 (sl)
WO (1) WO1994021674A1 (sl)
ZA (1) ZA941767B (sl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723578A (en) * 1987-09-24 1998-03-03 The Administrators Of Tulane Educational Fund Peptide analogs of bombesin
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US5650395A (en) * 1995-03-13 1997-07-22 Hurel; Steven Treatment of pulmonary hypertension
US6989371B1 (en) 1996-08-16 2006-01-24 Dabur Research Foundation Bombesin analogs for treatment of cancer
WO1998047524A1 (en) * 1997-04-22 1998-10-29 Curators Of The University Of Missouri Gastrin receptor-avid peptide conjugates
JP2004525864A (ja) * 2000-11-17 2004-08-26 ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー ボンベシンアンタゴニストを用いた性機能障害の治療
US7611692B2 (en) * 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) * 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US8420050B2 (en) * 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US20060239923A1 (en) * 2003-01-13 2006-10-26 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7922998B2 (en) * 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
CA2512310C (en) * 2003-01-13 2012-09-25 Bracco Imaging S.P.A. Improved linkers for radiopharmaceutical compounds
AU2004232314B2 (en) 2003-04-22 2007-11-22 Ipsen Pharma S.A.S. Peptide vectors
US7795385B2 (en) * 2004-12-17 2010-09-14 Bexar Global, Inc. Use of bombesin/gastrin-releasing peptide antagonists for the treatment of inflammatory conditions, acute lung injury and bipolar disorder
FR2918566B1 (fr) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
EP2100900A1 (en) * 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
EP2198878A1 (en) * 2008-12-18 2010-06-23 University Of Miami Polypeptide bombesin antagonists
CA2773713A1 (en) 2009-10-07 2011-04-14 Merck Sharp & Dohme Corp. Novel trpa1 antagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド
US5162497A (en) * 1987-09-24 1992-11-10 The Administrators Of The Tulane Educational Fund Bradykinin analogs with non-peptide bond
US5084555A (en) * 1989-08-21 1992-01-28 The Administrators Of The Tulane Educational Fund An octapeptide bombesin analog
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
AU638423B2 (en) * 1988-10-14 1993-07-01 The Administrators Of The Tulane Eductional Fund Therapeutic peptides
US5217955A (en) * 1989-09-15 1993-06-08 Biomeasure, Inc. Treatment of cancer with peptide analog of bombesin, grp, litorin or neuromedin
US5244883A (en) * 1990-11-29 1993-09-14 The Administrators Of The Tulane Educational Fund Nonapeptide bombesin antagonists

Also Published As

Publication number Publication date
CA2135787C (en) 2008-08-12
KR100306506B1 (ko) 2001-12-01
IL154995A0 (en) 2003-10-31
DK0646127T3 (da) 1999-04-12
HU218288B (en) 2000-07-28
KR950701646A (ko) 1995-04-28
CZ286750B6 (en) 2000-06-14
NO944293L (no) 1995-01-02
JPH07507330A (ja) 1995-08-10
PL180372B1 (pl) 2001-01-31
BR9404341A (pt) 1999-08-31
US5369094A (en) 1994-11-29
AU666270B2 (en) 1996-02-01
SK136494A3 (en) 1995-08-09
SI9420001B (sl) 1999-08-31
ES2120615T3 (es) 1998-11-01
IL108851A0 (en) 1994-06-24
DE69411342T2 (de) 1998-11-19
HRP940164A2 (en) 1996-08-31
JP3838656B2 (ja) 2006-10-25
EE03180B1 (et) 1999-04-15
RU94046091A (ru) 1996-09-27
ATE167874T1 (de) 1998-07-15
IL108851A (en) 2003-05-29
SI9420001A (en) 1995-08-31
CZ280794A3 (en) 1995-07-12
ZA941767B (en) 1994-10-06
DE69411342D1 (de) 1998-08-06
HUT69727A (en) 1995-09-28
FI945378A (fi) 1994-11-15
EP0646127B1 (en) 1998-07-01
HRP940164B1 (en) 2000-02-29
FI945378A0 (fi) 1994-11-15
EP0646127A1 (en) 1995-04-05
RU2114118C1 (ru) 1998-06-27
AU6444694A (en) 1994-10-11
NO944293D0 (no) 1994-11-10
NZ263668A (en) 1997-06-24
PL306209A1 (en) 1995-03-06
NO313418B1 (no) 2002-09-30
UA34456C2 (uk) 2001-03-15
WO1994021674A1 (en) 1994-09-29
TW325478B (en) 1998-01-21
CA2135787A1 (en) 1994-09-29
NZ299913A (en) 2000-07-28

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