ZA927724B - Cyclic vasoactive peptides - Google Patents

Cyclic vasoactive peptides

Info

Publication number
ZA927724B
ZA927724B ZA927724A ZA927724A ZA927724B ZA 927724 B ZA927724 B ZA 927724B ZA 927724 A ZA927724 A ZA 927724A ZA 927724 A ZA927724 A ZA 927724A ZA 927724 B ZA927724 B ZA 927724B
Authority
ZA
South Africa
Prior art keywords
peptide
amino acid
cyclic
vasoactive
chain
Prior art date
Application number
ZA927724A
Other languages
English (en)
Inventor
David Robert Bolin
Margaret O'donnell
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA927724B publication Critical patent/ZA927724B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA927724A 1991-10-11 1992-10-07 Cyclic vasoactive peptides ZA927724B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11

Publications (1)

Publication Number Publication Date
ZA927724B true ZA927724B (en) 1994-04-07

Family

ID=25099195

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA927724A ZA927724B (en) 1991-10-11 1992-10-07 Cyclic vasoactive peptides

Country Status (26)

Country Link
US (1) US5677419A (https=)
EP (1) EP0536741B1 (https=)
JP (1) JP2515473B2 (https=)
KR (1) KR970001580B1 (https=)
CN (3) CN1034943C (https=)
AT (1) ATE132165T1 (https=)
AU (1) AU656230B2 (https=)
BG (1) BG61125B2 (https=)
BR (1) BR9203959A (https=)
CA (1) CA2080272C (https=)
CZ (1) CZ281818B6 (https=)
DE (1) DE69207138T2 (https=)
DK (1) DK0536741T3 (https=)
ES (1) ES2082317T3 (https=)
FI (2) FI111646B (https=)
GR (1) GR3019326T3 (https=)
HU (2) HUT62606A (https=)
IL (3) IL117252A (https=)
MX (1) MX9205822A (https=)
NO (3) NO304523B1 (https=)
NZ (1) NZ244644A (https=)
RU (1) RU2095368C1 (https=)
SK (1) SK279399B6 (https=)
TW (1) TW305846B (https=)
UY (2) UY23488A1 (https=)
ZA (1) ZA927724B (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
AU722895B2 (en) * 1996-02-09 2000-08-10 F. Hoffmann-La Roche Ag Synthesis of VIP analog
EP0975374B1 (en) 1996-07-12 2007-12-05 Immunomedics, Inc. Radiometal-binding peptide analogues
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
RU2269354C2 (ru) * 1999-09-28 2006-02-10 Байер Корпорейшн Агонисты рецептора-3(r3) пептида-активатора гипофизарной аденилатциклазы(расар) и способы их фармакологического применения
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
US6608174B1 (en) 2000-02-18 2003-08-19 Dabur Research Foundation Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy
EP1257576B1 (en) * 2000-02-18 2004-09-15 Dabur Research Foundation Vasoactive intestinal peptide analogs
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
AU2002220720B2 (en) 2000-11-28 2006-09-14 Mondobiotech Ag Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
CA2488358A1 (en) 2002-06-10 2003-12-18 Mondobiotech Laboratories Anstalt Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis
AU2005208911A1 (en) * 2004-01-27 2005-08-11 Bayer Healthcare Llc Pituitary adenylate cyclase activating peptide (PACAP) receptor (VPAC2) agonists and their pharmacological methods of use
EP1781695A1 (en) * 2004-08-18 2007-05-09 Eli Lilly And Company Selective vpac2 receptor peptide agonists
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
RU2304146C2 (ru) * 2005-10-17 2007-08-10 Закрытое акционерное общество "Эпитек" Способ стабилизации петлеобразной структуры синтетических пептидов с помощью n- и c-концевых модификаций
CA2638733A1 (en) * 2006-02-28 2007-09-07 Eli Lilly And Company Selective vpac2 receptor peptide agonists
EP2041168A2 (en) * 2006-07-06 2009-04-01 F.Hoffmann-La Roche Ag Novel analogs of vasoactive intestinal peptide
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
DK3311828T3 (da) 2009-08-14 2021-06-28 Phasebio Pharmaceuticals Inc Modificerede vasoaktive tarmpeptider
CA2797033C (en) 2010-04-22 2021-10-19 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
WO2012170524A1 (en) 2011-06-06 2012-12-13 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
GB201421647D0 (en) * 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
CA2976038A1 (en) 2015-02-09 2016-08-18 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating muscle disease and disorders
SG11201902818PA (en) 2016-09-30 2019-05-30 Fujifilm Corp Cyclic peptide, affinity chromatography support, labeled antibody, antibody drug conjugate, and pharmaceutical preparation
CA3171988A1 (en) * 2020-02-22 2021-08-26 Jcr Pharmaceuticals Co., Ltd. Human transferrin receptor binding peptide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Also Published As

Publication number Publication date
NO980377L (no) 1993-04-13
CA2080272C (en) 2002-09-17
ATE132165T1 (de) 1996-01-15
NZ244644A (en) 1995-04-27
GR3019326T3 (en) 1996-06-30
JPH05213996A (ja) 1993-08-24
FI924580A0 (fi) 1992-10-09
FI20002041L (fi) 2000-09-15
IL103396A (en) 1997-11-20
FI111646B (fi) 2003-08-29
NO975023D0 (no) 1997-10-31
CN1225473C (zh) 2005-11-02
NO923929L (no) 1993-04-13
DE69207138T2 (de) 1996-06-13
EP0536741B1 (en) 1995-12-27
FI20002041A7 (fi) 2000-09-15
HU9203194D0 (en) 1992-12-28
AU656230B2 (en) 1995-01-27
IL103396A0 (en) 1993-03-15
KR970001580B1 (ko) 1997-02-11
CN1034943C (zh) 1997-05-21
HUT62606A (en) 1993-05-28
CN1198841C (zh) 2005-04-27
DK0536741T3 (da) 1996-04-22
NO304523B1 (no) 1999-01-04
SK308692A3 (en) 1995-03-08
NO980377D0 (no) 1998-01-28
UY23488A1 (es) 1993-04-20
IL117252A0 (en) 1996-06-18
EP0536741A2 (en) 1993-04-14
FI924580L (fi) 1993-04-12
DE69207138D1 (de) 1996-02-08
IL117252A (en) 1999-11-30
CA2080272A1 (en) 1993-04-12
ES2082317T3 (es) 1996-03-16
EP0536741A3 (https=) 1994-04-06
TW305846B (https=) 1997-05-21
UY25084A1 (es) 1998-12-21
US5677419A (en) 1997-10-14
RU2095368C1 (ru) 1997-11-10
JP2515473B2 (ja) 1996-07-10
NO923929D0 (no) 1992-10-09
CZ308692A3 (en) 1993-08-11
SK279399B6 (sk) 1998-11-04
CZ281818B6 (cs) 1997-02-12
BG61125B2 (bg) 1996-11-29
HU211534A9 (en) 1995-12-28
AU2622892A (en) 1993-04-22
KR930007972A (ko) 1993-05-20
NO975023L (no) 1993-04-13
CN1072415A (zh) 1993-05-26
CN1153785A (zh) 1997-07-09
MX9205822A (es) 1993-06-01
BR9203959A (pt) 1993-04-27
CN1152579A (zh) 1997-06-25

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