ZA924658B - Medicaments - Google Patents

Medicaments

Info

Publication number
ZA924658B
ZA924658B ZA924658A ZA924658A ZA924658B ZA 924658 B ZA924658 B ZA 924658B ZA 924658 A ZA924658 A ZA 924658A ZA 924658 A ZA924658 A ZA 924658A ZA 924658 B ZA924658 B ZA 924658B
Authority
ZA
South Africa
Prior art keywords
medicaments
Prior art date
Application number
ZA924658A
Other languages
English (en)
Inventor
Francis David King
Alberto Julio Kaumann
Laramie Mary Gaster
Rodney Christopher Young
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10697363&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA924658(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of ZA924658B publication Critical patent/ZA924658B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA924658A 1991-06-26 1992-06-24 Medicaments ZA924658B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919113802A GB9113802D0 (en) 1991-06-26 1991-06-26 Medicaments
US08/167,846 US5464864A (en) 1991-06-26 1992-06-17 Use of tetrahydrocarbazone derivatives as 5HT1 receptor agonists

Publications (1)

Publication Number Publication Date
ZA924658B true ZA924658B (en) 1993-12-24

Family

ID=10697363

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA924658A ZA924658B (en) 1991-06-26 1992-06-24 Medicaments

Country Status (35)

Country Link
US (2) US5464864A (hu)
EP (1) EP0591280B1 (hu)
JP (1) JP3261502B2 (hu)
KR (1) KR100251571B1 (hu)
CN (1) CN1034072C (hu)
AP (1) AP344A (hu)
AT (1) ATE170746T1 (hu)
BR (2) BR9206237A (hu)
CA (1) CA2113726C (hu)
CZ (3) CZ150696A3 (hu)
DE (2) DE69226953T2 (hu)
DK (1) DK0591280T3 (hu)
FI (1) FI103967B (hu)
GB (1) GB9113802D0 (hu)
HK (1) HK1014669A1 (hu)
HU (1) HU218907B (hu)
IE (1) IE922062A1 (hu)
IL (4) IL117105A0 (hu)
LU (1) LU90939I2 (hu)
MA (1) MA22563A1 (hu)
MX (1) MX9203444A (hu)
NL (1) NL300103I2 (hu)
NO (2) NO304774B1 (hu)
NZ (1) NZ243288A (hu)
PL (3) PL169392B1 (hu)
PT (1) PT100620B (hu)
RU (1) RU2137474C1 (hu)
SA (1) SA92130141B1 (hu)
SG (1) SG47877A1 (hu)
SI (1) SI9200125B (hu)
SK (3) SK280907B6 (hu)
TW (1) TW214544B (hu)
UA (1) UA41254C2 (hu)
WO (1) WO1993000086A1 (hu)
ZA (1) ZA924658B (hu)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
GB9226566D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
GB9226530D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
US5616603A (en) * 1995-05-26 1997-04-01 Smithkline Beecham Plc Enantiomers of carbazole derivatives as 5-HT1 -like agonists
US5618948A (en) * 1995-05-26 1997-04-08 Smithkline Beecham P.L.C. Process for preparing an enantiomer of a carbazole derivative
ES2151993T3 (es) * 1995-06-23 2001-01-16 Lilly Co Eli 1,2,3,4-tetrahidro-9h-carbazoles 6-sustituidos y 10h-ciclohepta(7,6-b)indoles 7-sustituidos.
US5917054A (en) * 1995-07-18 1999-06-29 Smithkline Beecham P.L.C. Process for preparing enantiomers of carbazole derivatives as 5-HT1 -like agonists
US5708187A (en) * 1996-06-27 1998-01-13 Eli Lilly And Company 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta 7,6-B!indoles: New 5-HT1F agonists
US5891885A (en) * 1996-10-09 1999-04-06 Algos Pharmaceutical Corporation Method for treating migraine
GB9723061D0 (en) * 1997-10-31 1998-01-07 Vanguard Medica Ltd Medicaments
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
GB9808069D0 (en) * 1998-04-16 1998-06-17 Vanguard Medica Ltd Novel processes
GB9817911D0 (en) * 1998-08-17 1998-10-14 Vanguard Medica Ltd New use
US20030017175A1 (en) * 2001-07-05 2003-01-23 R.T. Alamo Ventures I, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
US20030198669A1 (en) * 2001-07-05 2003-10-23 R.T. Alamo Ventures I, Llc Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine
US6685951B2 (en) 2001-07-05 2004-02-03 R. T. Alamo Ventures I, Inc. Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
ATE444965T1 (de) 2002-06-21 2009-10-15 Suven Life Sciences Ltd Sich als therapeutische mittel eignende arylalkylindole mit affinität für den serotoninrezeptor, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die diese enthalten
MXPA04012832A (es) 2002-06-21 2005-05-27 Suven Life Sciences Ltd Arilsulfonil indoles novedosos que tienen afinidad por el receptor de la serotonina, utiles como agentes terapeuticos, proceso para su preparacion y composiciones farmaceuticas que los contienen.
AU2003285759B2 (en) 2002-11-28 2010-01-28 Suven Life Sciences Limited N-arylsulfonyl-3-aminoalkoxyindoles
ATE401307T1 (de) 2002-11-28 2008-08-15 Suven Life Sciences Ltd N-arylsulfonyl-2-substituierte indole mit affinität zum serotonin rezeptor, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
EP1581538B1 (en) 2002-12-18 2007-02-28 Suven Life Sciences Limited Tetracyclic 3-substituted indoles having serotonin receptor affinity
EP2316824A1 (en) * 2006-08-07 2011-05-04 Actelion Pharmaceuticals Ltd. (3-Amino-1,2,3,4-tetrahydro-9H-carbazoI-9-yl)-acetic acid derivates
JP2010522135A (ja) 2006-10-09 2010-07-01 チャールストン ラボラトリーズ，インコーポレイテッド 医薬組成物
JP5825757B2 (ja) 2007-02-11 2015-12-02 マップ・ファーマシューティカルズ・インコーポレイテッド 副作用プロファイルを最小限にしながら片頭痛の迅速な緩和を可能にするｄｈｅの治療上の投与方法
US20090069399A1 (en) * 2007-09-12 2009-03-12 Protia, Llc Deuterium-enriched frovatriptan
CA3066426A1 (en) 2008-01-09 2009-07-16 Charleston Laboratories, Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
WO2010073253A1 (en) * 2008-12-22 2010-07-01 Natco Pharma Limited Method for preparing an optically active frovatriptan
WO2011006012A1 (en) 2009-07-08 2011-01-13 Charleston Laboratories Inc. Pharmaceutical compositions
WO2011050140A1 (en) 2009-10-22 2011-04-28 Blue Fury Consulting, L.L.C. Posterior cervical fusion system and techniques
US10098674B2 (en) 2009-10-22 2018-10-16 Nuvasive, Inc. System and method for posterior cervical fusion
WO2013016223A2 (en) 2011-07-22 2013-01-31 The University Of Chicago Treatments for migraine and related disorders
WO2014100351A2 (en) 2012-12-21 2014-06-26 Map Pharmaceuticals, Inc. 8'-hydroxy-dihydroergotamine compounds and compositions
EP2816030A1 (en) 2013-06-20 2014-12-24 Duke Chem, S. A. Process for the preparation of frovatriptan and its enantiomer
GB201312768D0 (en) * 2013-07-17 2013-08-28 Ge Healthcare Ltd Work-up procedure
US10179109B2 (en) 2016-03-04 2019-01-15 Charleston Laboratories, Inc. Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates
EP3766483A1 (en) 2019-07-19 2021-01-20 BioPharma Synergies, S. L. Orodispersible powder composition comprising a triptan

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642816A (en) * 1967-08-10 1972-02-15 Sterling Drug Inc 3-acetamido-1 2 3 4-tetrahydrocarbazole
US3959309A (en) * 1968-01-24 1976-05-25 Sterling Drug Inc. 3-Amido-1,2,3,4-tetrahydrocarbazoles
US4062864A (en) * 1968-01-24 1977-12-13 Sterling Drug Inc. 3-Hydroxy carbazole derivatives
US3592824A (en) * 1970-03-12 1971-07-13 Miles Lab 3-substituted amino-1,2,3,4-tetrahydrocarbazoles
BE787537A (fr) * 1971-08-16 1973-02-14 Sterling Drug Inc Tetrahydrocarbazoles
US4172834A (en) * 1971-08-16 1979-10-30 Sterling Drug Inc. 3-Amino-tetrahydrocarbazoles
US4257952A (en) * 1977-06-06 1981-03-24 Sterling Drug Inc. 3-Amino-tetrahydrocarbazoles
US4254134A (en) * 1978-03-17 1981-03-03 Endo Laboratories, Inc. Antidepressant 2-amino- and -2-(substituted amino)-cis-hexahydro-carbazoles
EP0115607A1 (de) * 1983-01-04 1984-08-15 MERCK PATENT GmbH Tetrahydrocarbazolderivate

Also Published As

Publication number Publication date
UA41254C2 (uk) 2001-09-17
NL300103I1 (nl) 2002-12-02
AU1977592A (en) 1993-01-25
FI103967B1 (fi) 1999-10-29
NO934800L (no) 1993-12-23
WO1993000086A1 (en) 1993-01-07
IL117105A0 (en) 1996-06-18
DK0591280T3 (da) 1999-02-15
SK280905B6 (sk) 2000-09-12
DE10299042I1 (de) 2003-02-20
CA2113726A1 (en) 1993-01-07
AP344A (en) 1994-07-05
KR100251571B1 (ko) 2000-07-01
CZ286193A3 (en) 1994-07-13
CZ282327B6 (cs) 1997-06-11
NO2005011I1 (no) 2005-05-18
NL300103I2 (nl) 2003-02-03
IE922062A1 (en) 1992-12-30
MA22563A1 (fr) 1992-12-31
AP9200403A0 (en) 1992-07-31
NZ243288A (en) 1994-09-27
PL169392B1 (pl) 1996-07-31
MX9203444A (es) 1993-12-01
FI103967B (fi) 1999-10-29
PT100620A (pt) 1993-09-30
SI9200125A (en) 1992-12-31
HU218907B (hu) 2000-12-28
NO304774B1 (no) 1999-02-15
PL171034B1 (en) 1997-02-28
EP0591280A1 (en) 1994-04-13
ATE170746T1 (de) 1998-09-15
LU90939I2 (fr) 2002-09-24
BR1100460A (pt) 2000-07-18
CZ150596A3 (en) 1997-05-14
PT100620B (pt) 1999-01-29
GB9113802D0 (en) 1991-08-14
CZ150696A3 (en) 1997-06-11
FI935842A0 (fi) 1993-12-23
PL169410B1 (pl) 1996-07-31
EP0591280B1 (en) 1998-09-09
SK280906B6 (sk) 2000-09-12
TW214544B (hu) 1993-10-11
CZ282083B6 (cs) 1997-05-14
SG47877A1 (en) 1998-04-17
SA92130141B1 (ar) 2005-12-18
NO2005011I2 (no) 2008-02-11
JPH06508827A (ja) 1994-10-06
RU2137474C1 (ru) 1999-09-20
BR9206237A (pt) 1995-04-11
SK131993A3 (en) 1994-06-08
CA2113726C (en) 2008-02-19
IL102322A (en) 1997-09-30
SK280907B6 (sk) 2000-09-12
HUT68961A (en) 1995-08-28
SI9200125B (en) 2001-12-31
US5637611A (en) 1997-06-10
US5464864A (en) 1995-11-07
CN1069726A (zh) 1993-03-10
IL117104A (en) 1997-09-30
JP3261502B2 (ja) 2002-03-04
FI935842A (fi) 1993-12-23
IL102322A0 (en) 1993-01-14
CZ282061B6 (cs) 1997-05-14
AU652842B2 (en) 1994-09-08
CN1034072C (zh) 1997-02-19
NO934800D0 (no) 1993-12-23
DE10299042I2 (de) 2005-02-03
HK1014669A1 (en) 1999-09-30
DE69226953D1 (de) 1998-10-15
DE69226953T2 (de) 1999-05-12
IL117105A (en) 1998-01-04
IL117104A0 (en) 1996-06-18

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