ZA917748B - Process for the preparation of water soluble camptothecin analogs and intermediates thereof,compounds prepared by said process,and methods of use thereof - Google Patents

Process for the preparation of water soluble camptothecin analogs and intermediates thereof,compounds prepared by said process,and methods of use thereof

Info

Publication number
ZA917748B
ZA917748B ZA917748A ZA917748A ZA917748B ZA 917748 B ZA917748 B ZA 917748B ZA 917748 A ZA917748 A ZA 917748A ZA 917748 A ZA917748 A ZA 917748A ZA 917748 B ZA917748 B ZA 917748B
Authority
ZA
South Africa
Prior art keywords
preparation
water soluble
intermediates
methods
compounds prepared
Prior art date
Application number
ZA917748A
Other languages
English (en)
Inventor
Joseph Marian Fortunak
Marian Fortunak Joseph
Antonietta Rose Mastrocola
Rose Mastrocola Antonietta
Patrick Lee Burk
Lee Burk Patrick
Jeffery Lee Wood
Lee Wood Jeffery
Mark Millinger
Millinger Mark
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA917748B publication Critical patent/ZA917748B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Steroid Compounds (AREA)
ZA917748A 1990-09-28 1991-09-27 Process for the preparation of water soluble camptothecin analogs and intermediates thereof,compounds prepared by said process,and methods of use thereof ZA917748B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58964390A 1990-09-28 1990-09-28

Publications (1)

Publication Number Publication Date
ZA917748B true ZA917748B (en) 1992-09-30

Family

ID=24358879

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA917748A ZA917748B (en) 1990-09-28 1991-09-27 Process for the preparation of water soluble camptothecin analogs and intermediates thereof,compounds prepared by said process,and methods of use thereof

Country Status (24)

Country Link
US (1) US5734056A (cg-RX-API-DMAC7.html)
EP (1) EP0547165B1 (cg-RX-API-DMAC7.html)
JP (1) JP2848958B2 (cg-RX-API-DMAC7.html)
CN (1) CN1033509C (cg-RX-API-DMAC7.html)
AT (1) ATE186461T1 (cg-RX-API-DMAC7.html)
AU (1) AU664830B2 (cg-RX-API-DMAC7.html)
CA (1) CA2090967C (cg-RX-API-DMAC7.html)
CZ (1) CZ51593A3 (cg-RX-API-DMAC7.html)
DE (1) DE69131775T2 (cg-RX-API-DMAC7.html)
DK (1) DK0547165T3 (cg-RX-API-DMAC7.html)
ES (1) ES2137932T3 (cg-RX-API-DMAC7.html)
FI (1) FI931384A0 (cg-RX-API-DMAC7.html)
GR (1) GR3031823T3 (cg-RX-API-DMAC7.html)
HU (1) HUT70024A (cg-RX-API-DMAC7.html)
IE (1) IE913402A1 (cg-RX-API-DMAC7.html)
IL (1) IL99571A (cg-RX-API-DMAC7.html)
NO (1) NO931153L (cg-RX-API-DMAC7.html)
NZ (1) NZ239947A (cg-RX-API-DMAC7.html)
PT (1) PT99109B (cg-RX-API-DMAC7.html)
SI (1) SI9111599A (cg-RX-API-DMAC7.html)
SK (1) SK283693B6 (cg-RX-API-DMAC7.html)
WO (1) WO1992005785A1 (cg-RX-API-DMAC7.html)
YU (1) YU159991A (cg-RX-API-DMAC7.html)
ZA (1) ZA917748B (cg-RX-API-DMAC7.html)

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CN103145720B (zh) * 2013-02-20 2015-09-30 上海北卡医药技术有限公司 一种10-羟基喜树碱的一水合物的制备方法
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CN109475590A (zh) * 2016-03-08 2019-03-15 成氏实验室有限公司 用以提升人体酸碱度从酸性变为碱性的中药配方制剂
CN115551552A (zh) 2020-02-25 2022-12-30 祐方有限公司 喜树碱衍生物及其缀合物
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Also Published As

Publication number Publication date
FI931384L (fi) 1993-03-26
CN1033509C (zh) 1996-12-11
JP2848958B2 (ja) 1999-01-20
SK283693B6 (sk) 2003-12-02
HU9300878D0 (en) 1993-06-28
DE69131775D1 (de) 1999-12-16
HUT70024A (en) 1995-09-28
AU8739991A (en) 1992-04-28
US5734056A (en) 1998-03-31
NO931153D0 (no) 1993-03-26
WO1992005785A1 (en) 1992-04-16
JPH06501476A (ja) 1994-02-17
CA2090967A1 (en) 1992-03-29
EP0547165B1 (en) 1999-11-10
EP0547165A1 (en) 1993-06-23
PT99109A (pt) 1992-08-31
EP0547165A4 (cg-RX-API-DMAC7.html) 1994-03-30
SI9111599A (sl) 1998-02-28
IE913402A1 (en) 1992-04-08
IL99571A0 (en) 1992-08-18
FI931384A7 (fi) 1993-03-26
PT99109B (pt) 1999-02-26
CZ51593A3 (en) 1994-01-19
GR3031823T3 (en) 2000-02-29
ES2137932T3 (es) 2000-01-01
SK25993A3 (en) 1993-07-07
IL99571A (en) 2000-08-31
CA2090967C (en) 2007-02-06
AU664830B2 (en) 1995-12-07
NO931153L (no) 1993-03-26
NZ239947A (en) 1994-07-26
ATE186461T1 (de) 1999-11-15
DK0547165T3 (da) 2000-03-27
HK1012283A1 (en) 1999-07-30
FI931384A0 (fi) 1993-03-26
CN1062731A (zh) 1992-07-15
YU159991A (sh) 1994-06-10
DE69131775T2 (de) 2000-04-20

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