JPS5436282A - Preparation of substituted piperazine - Google Patents
Preparation of substituted piperazineInfo
- Publication number
- JPS5436282A JPS5436282A JP10013077A JP10013077A JPS5436282A JP S5436282 A JPS5436282 A JP S5436282A JP 10013077 A JP10013077 A JP 10013077A JP 10013077 A JP10013077 A JP 10013077A JP S5436282 A JPS5436282 A JP S5436282A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- substituted piperazine
- substituted
- piperarazine
- methacrylophenone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N diethylenediamine Natural products C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
- 150000004885 piperazines Chemical class 0.000 title 1
- KJCFAQDTHMIAAN-UHFFFAOYSA-N 2-methyl-1-phenylprop-2-en-1-one Chemical compound CC(=C)C(=O)C1=CC=CC=C1 KJCFAQDTHMIAAN-UHFFFAOYSA-N 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
Abstract
PURPOSE: To prepare the title compound useful as a medicine having antitussive, sedative, or antihistaminic activity, by reacting a 1-substituted piperarazine derivative or its salt with a readily available methacrylophenone.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10013077A JPS5436282A (en) | 1977-08-23 | 1977-08-23 | Preparation of substituted piperazine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10013077A JPS5436282A (en) | 1977-08-23 | 1977-08-23 | Preparation of substituted piperazine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5436282A true JPS5436282A (en) | 1979-03-16 |
Family
ID=14265724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10013077A Pending JPS5436282A (en) | 1977-08-23 | 1977-08-23 | Preparation of substituted piperazine |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5436282A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54160388A (en) * | 1978-06-07 | 1979-12-19 | Permachem Asia Ltd | Manufacture of 1*44di substituted piperazine |
-
1977
- 1977-08-23 JP JP10013077A patent/JPS5436282A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54160388A (en) * | 1978-06-07 | 1979-12-19 | Permachem Asia Ltd | Manufacture of 1*44di substituted piperazine |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3064749D1 (en) | New pyrazoline derivatives, method of preparing the new compounds, as well as insecticidal composition on the basis of these new compounds | |
| JPS5395977A (en) | 1,4-dihydropyrimidine compounds and process for their preparation | |
| JPS52128210A (en) | Preparation of soft capsule for 1alpha-hydroxyvitamind derivatives | |
| PT84716A (en) | Process for the preparation of insecticidal compositions containing six-membered heterocyclic derivatives of n:-substituted-n,n:-diacylhydrazines | |
| JPS5419931A (en) | Separation of threo, erythro-3-(3,4-dibenzyloxyphenyl)serines | |
| JPS5344580A (en) | 1,6-dihydropyridazine derivatives | |
| JPS5436282A (en) | Preparation of substituted piperazine | |
| JPS5424882A (en) | Novel heterocyclic compounds and their preparation | |
| JPS52113973A (en) | Synthesis of benzotriazole derivatives | |
| JPS5424856A (en) | 1-(3 or 4-methyl-3-cyclohexenyl)-2-methyl-1-penten-3-ol | |
| JPS5422380A (en) | Preparation of substituted pipebrazine | |
| JPS53127466A (en) | Thiocarbamate type heterocyclic compounds and its preparation | |
| JPS5422379A (en) | Preparation of piperazine derivative | |
| JPS5424888A (en) | Novel 7alpha-methoxycephalosporins and their preparation | |
| JPS53147054A (en) | 3-hydroxymethyl-4-homobrendane | |
| JPS52156879A (en) | Preparation of piperazine derivatives | |
| ES462071A1 (en) | Pyrimidine derivative | |
| JPS5416451A (en) | 3,5-dichloro-4-fluoropheyl isocyanate and its preparation | |
| JPS53147055A (en) | 3-carboxy-4-homobrendane | |
| JPS5368790A (en) | Preparation of 1-(2'-tetrahydrofuryl)-5-fluorouracil | |
| JPS545976A (en) | 7-glycylprolylamino-4-methylcoumalin | |
| JPS5432438A (en) | Preparation of tyrosinol derivatives | |
| JPS5430181A (en) | 3,4-dihydrocarbostyril derivative | |
| JPS5353684A (en) | Preparation of dibenzazepin derivatives | |
| JPS5432452A (en) | 2-(2-pentynyl)cyclopentanol derivative and its preparation |