US5712374A
(en)
*
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
EP0855911A4
(de)
*
|
1995-10-20 |
1998-10-14 |
Univ Utah Res Found |
Namenamicin, ein endiyn-antitumor-antibiotikum aus der meeresascidiacea polysyncraton lithostrotum
|
US20040001827A1
(en)
*
|
2002-06-28 |
2004-01-01 |
Dennis Mark S. |
Serum albumin binding peptides for tumor targeting
|
ATE337403T1
(de)
*
|
1999-12-24 |
2006-09-15 |
Genentech Inc |
Verfahren und verbindungen zur verlängerung der halbwertzeiten bei der ausscheidung von biowirksamen verbindungen
|
US20050287153A1
(en)
*
|
2002-06-28 |
2005-12-29 |
Genentech, Inc. |
Serum albumin binding peptides for tumor targeting
|
US20060228364A1
(en)
*
|
1999-12-24 |
2006-10-12 |
Genentech, Inc. |
Serum albumin binding peptides for tumor targeting
|
US20040023910A1
(en)
*
|
2001-09-28 |
2004-02-05 |
Zhiming Zhang |
Use of cyr61 in the treatment and diagnosis of human uterine leiomyomas
|
US20110045005A1
(en)
|
2001-10-19 |
2011-02-24 |
Craig Crowley |
Compositions and methods for the treatment of tumor of hematopoietic origin
|
SG187991A1
(en)
|
2002-05-02 |
2013-03-28 |
Wyeth Corp |
Calicheamicin derivative-carrier conjugates
|
EP1664115A2
(de)
*
|
2003-08-01 |
2006-06-07 |
Genentech, Inc. |
Antikörper cdr polypeptid-sequenzen mit limitierter diversität
|
US20050282168A1
(en)
*
|
2003-09-29 |
2005-12-22 |
Wyeth |
Cell surface molecules as markers and therapeutic agents against kidney cancers
|
KR101438983B1
(ko)
|
2003-11-06 |
2014-09-05 |
시애틀 지네틱스, 인크. |
리간드에 접합될 수 있는 모노메틸발린 화합물
|
NZ547438A
(en)
|
2003-12-19 |
2010-01-29 |
Genentech Inc |
Monovalent antibody fragments useful as therapeutics
|
AR048098A1
(es)
*
|
2004-03-15 |
2006-03-29 |
Wyeth Corp |
Conjugados de caliqueamicina
|
RU2404810C9
(ru)
|
2004-06-01 |
2015-06-20 |
Дженентек, Инк. |
Конъюгаты антитело-лекарственное средство и способы
|
US20060222850A1
(en)
*
|
2005-04-01 |
2006-10-05 |
The University Of Chicago |
Synthesis of a self assembled hybrid of ultrananocrystalline diamond and carbon nanotubes
|
DK1784426T3
(da)
*
|
2004-09-03 |
2012-03-12 |
Genentech Inc |
Humaniserede anti-beta7-antagonister og anvendelser deraf
|
WO2006031653A2
(en)
*
|
2004-09-10 |
2006-03-23 |
Wyeth |
Humanized anti-5t4 antibodies and anti-5t4 antibody / calicheamicin conjugates
|
HUE030079T2
(en)
|
2004-09-23 |
2017-04-28 |
Genentech Inc |
Cysteine-manipulated antibodies and conjugates
|
BRPI0516577A
(pt)
*
|
2004-10-05 |
2008-09-16 |
Genentech Inc |
agentes terapêuticos com toxicidade diminuìda
|
JP4993645B2
(ja)
|
2004-12-01 |
2012-08-08 |
ジェネンテック, インコーポレイテッド |
抗体薬剤結合体および方法
|
WO2007094842A2
(en)
*
|
2005-12-02 |
2007-08-23 |
Genentech, Inc. |
Binding polypeptides and uses thereof
|
US20070003559A1
(en)
*
|
2005-07-01 |
2007-01-04 |
Wyeth |
Methods of determining pharmacokinetics of targeted therapies
|
EP1957531B1
(de)
|
2005-11-07 |
2016-04-13 |
Genentech, Inc. |
Bindungspolypeptide mit diversifizierten und konsensus-vh/vl-hypervariablen sequenzen
|
US20070237764A1
(en)
*
|
2005-12-02 |
2007-10-11 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
JP2009518418A
(ja)
*
|
2005-12-06 |
2009-05-07 |
ワイス |
インターロイキン11組成物および使用法
|
EP3309170B1
(de)
|
2005-12-15 |
2019-05-22 |
Genentech, Inc. |
Polyubiquitin-antikörper
|
EP2402373B1
(de)
|
2006-01-05 |
2016-10-19 |
Genentech, Inc. |
ANTI-EPHB4-Antikörper sowie Verfahren zu deren Verwendung
|
TW200806685A
(en)
*
|
2006-02-21 |
2008-02-01 |
Wyeth Corp |
Processes for the convergent synthesis of calicheamicin derivatives
|
DK2368914T3
(en)
|
2006-03-10 |
2019-03-04 |
Wyeth Llc |
Anti-5T4 antibodies and uses thereof
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
NZ597251A
(en)
|
2006-05-30 |
2013-08-30 |
Genentech Inc |
Antibodies and immunoconjugates and uses therefor
|
RS53942B1
(en)
|
2006-10-27 |
2015-08-31 |
Genentech Inc. |
Antibodies and Immunoconjugates and Their Use
|
CN101652389A
(zh)
|
2007-02-09 |
2010-02-17 |
健泰科生物技术公司 |
抗robo4抗体及其用途
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
PT2465541T
(pt)
|
2007-05-22 |
2018-10-17 |
Wyeth Llc |
Processos melhorados para fabricar hidrazidas
|
PE20090309A1
(es)
*
|
2007-06-04 |
2009-04-18 |
Wyeth Corp |
Conjugado portador-caliqueamicina y un metodo de deteccion de caliqueamicina
|
PE20090321A1
(es)
|
2007-06-04 |
2009-04-20 |
Genentech Inc |
Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
|
TWI468417B
(zh)
|
2007-11-30 |
2015-01-11 |
Genentech Inc |
抗-vegf抗體
|
KR20100107501A
(ko)
|
2008-01-18 |
2010-10-05 |
메디뮨 엘엘씨 |
부위 특이적 접합을 위한 시스테인 조작 항체
|
KR20180132156A
(ko)
|
2008-04-09 |
2018-12-11 |
제넨테크, 인크. |
면역 관련 질병의 치료를 위한 신규한 조성물 및 방법
|
PL2279004T3
(pl)
*
|
2008-05-16 |
2015-06-30 |
Hoffmann La Roche |
Zastosowanie biomarkerów do oceny leczenia zaburzeń zapalnych przewodu pokarmowego antagonistami integryny beta7
|
US8680020B2
(en)
|
2008-07-15 |
2014-03-25 |
Academia Sinica |
Glycan arrays on PTFE-like aluminum coated glass slides and related methods
|
TWI461211B
(zh)
|
2009-03-20 |
2014-11-21 |
Genentech Inc |
抗-her抗體
|
EP3702371B1
(de)
|
2009-03-25 |
2022-11-02 |
Genentech, Inc. |
Anti-fgfr3-antikörper und verfahren damit
|
WO2011005481A1
(en)
|
2009-06-22 |
2011-01-13 |
Medimmune, Llc |
ENGINEERED Fc REGIONS FOR SITE-SPECIFIC CONJUGATION
|
DK2473522T3
(en)
|
2009-09-02 |
2016-11-28 |
Genentech Inc |
Smoothened MUTANT AND METHODS OF USING THE SAME
|
KR20120106940A
(ko)
*
|
2009-10-19 |
2012-09-27 |
제넨테크, 인크. |
간세포 성장 인자 활성화제의 조절제
|
NZ599337A
(en)
|
2009-10-22 |
2013-05-31 |
Genentech Inc |
Anti-hepsin antibodies and methods using same
|
KR20120105446A
(ko)
|
2009-10-22 |
2012-09-25 |
제넨테크, 인크. |
대식세포-자극 단백질의 헵신 활성화를 조정하기 위한 방법 및 조성물
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
WO2011056494A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor-like kinase-1 antagonist and vegfr3 antagonist combinations
|
AU2010314981B2
(en)
|
2009-11-05 |
2015-07-02 |
Genentech, Inc. |
Methods and composition for secretion of heterologous polypeptides
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
AR078377A1
(es)
|
2009-12-11 |
2011-11-02 |
Genentech Inc |
Anticuerpos anti-vegf-c (factor de crecimiento endotelial anti-vascular aislado c) y sus metodos de uso
|
SI2516465T1
(sl)
|
2009-12-23 |
2016-08-31 |
F. Hoffmann-La Roche Ag |
Protelesa proti bv8 in uporaba le-teh
|
KR101723615B1
(ko)
|
2010-01-12 |
2017-04-06 |
한상선 |
천연 한약재를 이용한 샴푸 조성물
|
AU2011213609B2
(en)
|
2010-02-08 |
2016-11-03 |
Agensys, Inc. |
Antibody drug conjugates (ADC) that bind to 161P2F10B proteins
|
US10338069B2
(en)
|
2010-04-12 |
2019-07-02 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
CA2795972A1
(en)
|
2010-06-03 |
2011-12-08 |
Genentech, Inc. |
Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
|
PL3409287T3
(pl)
|
2010-09-29 |
2021-09-27 |
Agensys, Inc. |
Koniugaty leków i przeciwciał (adc), które wiążą białka 191p4d12
|
US8481680B2
(en)
|
2010-10-05 |
2013-07-09 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
DK2668210T3
(da)
|
2011-01-26 |
2020-08-24 |
Celldex Therapeutics Inc |
Anti-kit antistoffer og anvendelser deraf
|
BR112014009953A2
(pt)
|
2011-10-28 |
2017-12-05 |
Genentech Inc |
método de inibição do crescimento de tumores, de tratamento de melanoma, artigo industrializado e uso
|
EP2589609A1
(de)
|
2011-11-03 |
2013-05-08 |
Pierre Fabre Medicament |
Antigenbindendes Protein und dessen Verwendung als Adressierungsprodukt bei der Behandlung von Krebs
|
CN102584915B
(zh)
*
|
2011-12-31 |
2014-07-23 |
沈阳药科大学 |
一种芳香酸类化合物及其用途
|
EP3663314A1
(de)
|
2012-01-09 |
2020-06-10 |
The Scripps Research Institute |
Humanisierte antikörper mit ultralangem cdr3s
|
US20140050720A1
(en)
|
2012-01-09 |
2014-02-20 |
The Scripps Research Institute |
Ultralong complementarity determining regions and uses thereof
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
KR20150036274A
(ko)
|
2012-07-19 |
2015-04-07 |
알레시아 바이오쎄라퓨틱스 인코포레이티드 |
항-siglec-15 항체
|
DK2877493T3
(en)
|
2012-07-25 |
2018-06-14 |
Celldex Therapeutics Inc |
ANTI-KIT ANTIBODIES AND APPLICATIONS THEREOF
|
WO2014031498A1
(en)
|
2012-08-18 |
2014-02-27 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
BR112015003751B1
(pt)
|
2012-08-23 |
2021-12-07 |
Agensys, Inc. |
Conjugados anticorpo-fármaco, uso dos mesmos, composição farmacêutica, vetor, anticorpos ou fragmentos de ligação ao antígeno, método para produzir os mesmos e anticorpo ou fragmento de ligação ao antígeno que se liga a 158p1d7
|
US9624308B2
(en)
|
2012-11-05 |
2017-04-18 |
Pierre Fabre Medicament |
Antigen binding proteins
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
US9981030B2
(en)
|
2013-06-27 |
2018-05-29 |
Academia Sinica |
Glycan conjugates and use thereof
|
US10640574B2
(en)
|
2013-07-18 |
2020-05-05 |
Taurus Biosciences, Llc |
Humanized antibodies with ultralong complementary determining regions
|
WO2015017146A2
(en)
|
2013-07-18 |
2015-02-05 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
RU2679657C2
(ru)
|
2013-08-01 |
2019-02-12 |
Эдженсис, Инк. |
Конъюгаты антител с лекарственными средствами, связывающиеся с белками cd37
|
AU2014317889B2
(en)
|
2013-09-06 |
2020-03-05 |
Academia Sinica |
Human iNKT cell activation using glycolipids with altered glycosyl groups
|
RU2016119491A
(ru)
|
2013-11-04 |
2017-12-11 |
Пфайзер Инк. |
Конъюгаты антитела к efna4 с лекарственным средством
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
JP2017507118A
(ja)
|
2014-01-16 |
2017-03-16 |
アカデミア シニカAcademia Sinica |
がんの処置および検出のための組成物および方法
|
CN105636591B
(zh)
|
2014-01-29 |
2020-04-07 |
上海恒瑞医药有限公司 |
配体-细胞毒性药物偶联物、其制备方法及其应用
|
JP6736467B2
(ja)
|
2014-02-04 |
2020-08-05 |
ジェネンテック, インコーポレイテッド |
平滑化変異体及びその使用方法
|
EP3129767B1
(de)
|
2014-03-27 |
2021-09-01 |
Academia Sinica |
Reaktive markierungsverbindungen und ihre verwendungen
|
CN112851808B
(zh)
|
2014-04-25 |
2024-12-06 |
皮埃尔法布雷医药公司 |
Igf-1r抗体及其作为定位载体用于治疗癌症的用途
|
HUE053287T2
(hu)
|
2014-04-30 |
2021-06-28 |
Pfizer |
PTK-7 elleni ellenanyag-drog konjugátumok
|
CN106573971A
(zh)
|
2014-05-27 |
2017-04-19 |
中央研究院 |
抗cd20醣抗体及其用途
|
TWI679020B
(zh)
|
2014-05-27 |
2019-12-11 |
中央研究院 |
抗her2醣抗體及其用途
|
EP3149161B1
(de)
|
2014-05-27 |
2021-07-28 |
Academia Sinica |
Fucosidase aus bacteroiden und verfahren damit
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
CN106714829A
(zh)
|
2014-05-28 |
2017-05-24 |
中央研究院 |
抗TNF‑α醣抗体及其用途
|
WO2016034968A1
(en)
|
2014-09-02 |
2016-03-10 |
Pfizer Inc. |
Therapeutic antibody
|
KR102422375B1
(ko)
|
2014-09-08 |
2022-07-18 |
아카데미아 시니카 |
당지질을 사용한 인간 iNKT 세포 활성화
|
EP3215533A2
(de)
|
2014-11-05 |
2017-09-13 |
F. Hoffmann-La Roche AG |
Anti-fgfr2/3-antikörper und verfahren zur verwendung davon
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
CN107430127B
(zh)
|
2015-01-24 |
2020-08-28 |
中央研究院 |
癌症标记及其使用方法
|
AU2015378564A1
(en)
|
2015-01-24 |
2017-07-13 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
AU2016215227A1
(en)
|
2015-02-04 |
2017-09-21 |
Assistance Publique-Hopitaux De Paris |
Mutant smoothened and methods of using the same
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
DK3383920T3
(da)
|
2015-11-30 |
2024-04-02 |
Univ California |
Levering af tumorspecifik nyttelast og immunaktivering ved hjælp af et humant antistof rettet mod et meget specifikt tumorcelleoverfladeantigen
|
CA3019952A1
(en)
|
2016-02-04 |
2017-08-10 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
WO2017153432A1
(en)
|
2016-03-07 |
2017-09-14 |
Pierre Fabre Medicament |
A new universal method to capture and analyze adcs for characterization of drug distribution and the drug-to-antibody ratio in biological samples
|
EP3426693A4
(de)
|
2016-03-08 |
2019-11-13 |
Academia Sinica |
Verfahren zur modularen synthese von n-glykanen und anordnungen davon
|
CN109641037B
(zh)
|
2016-04-13 |
2022-09-06 |
西安奥瑞单抗生物技术有限公司 |
抗psma抗体及其用途
|
TW202434291A
(zh)
|
2016-07-08 |
2024-09-01 |
美商建南德克公司 |
人類副睪蛋白4 (he4)用於評定癌症治療反應性之用途
|
EP3500594A4
(de)
|
2016-08-22 |
2020-03-11 |
Cho Pharma Inc. |
Antikörper, bindungsfragmente und verfahren zur verwendung
|
WO2019018647A1
(en)
|
2017-07-20 |
2019-01-24 |
Pfizer Inc. |
ANTI-GD3 ANTIBODIES AND CONJUGATES ANTIBODY-MEDICATION
|
CN111683686A
(zh)
|
2017-12-06 |
2020-09-18 |
西纳福克斯股份有限公司 |
烯二炔缀合物
|
JP2021532116A
(ja)
|
2018-07-23 |
2021-11-25 |
マジェンタ セラピューティクス インコーポレイテッドMagenta Therapeutics, Inc. |
同種異系の細胞療法における抗−cd5抗体薬物コンジュゲート(adc)の使用
|
EP3858386A4
(de)
|
2018-09-26 |
2022-10-12 |
Jiangsu Hengrui Medicine Co., Ltd. |
Ligand-wirkstoff-konjugat aus exateca-analogon, verfahren zu seiner herstellung und seine verwendung
|
JPWO2021010326A1
(de)
|
2019-07-12 |
2021-01-21 |
|
|
CA3150807A1
(en)
|
2019-09-04 |
2021-03-11 |
Y-Biologics Inc. |
Anti-vsig4 antibody or antigen binding fragment and uses thereof
|
MX2022009044A
(es)
|
2020-01-22 |
2022-08-11 |
Shanghai Senhui Medicine Co Ltd |
Conjugado de farmaco de derivado de eribulin, metodo de preparacion y aplicacion del mismo en medicina.
|
KR20220157998A
(ko)
|
2020-03-25 |
2022-11-29 |
지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 |
항체 약물 접합체를 포함하는 약학적 조성물 및 이의 용도
|
JP2023521956A
(ja)
|
2020-03-25 |
2023-05-26 |
江蘇恒瑞医薬股▲ふん▼有限公司 |
抗体薬物複合体の調製方法
|
KR20230156727A
(ko)
|
2021-03-03 |
2023-11-14 |
피에르 파브르 메디카먼트 |
항-vsig4 항체 또는 이의 항원 결합 단편 및 용도
|
TW202309088A
(zh)
|
2021-04-30 |
2023-03-01 |
法商皮爾法伯製藥公司 |
新的穩定抗vista抗體
|