SK188390A3 - N-acyl derivatives of ll-e33288 antibiotics, process for their preparation and their use in production of drugs - Google Patents

N-acyl derivatives of ll-e33288 antibiotics, process for their preparation and their use in production of drugs Download PDF

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Publication number
SK188390A3
SK188390A3 SK1883-90A SK188390A SK188390A3 SK 188390 A3 SK188390 A3 SK 188390A3 SK 188390 A SK188390 A SK 188390A SK 188390 A3 SK188390 A3 SK 188390A3
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SK
Slovakia
Prior art keywords
group
general formula
methyl
ethyl acetate
formula
Prior art date
Application number
SK1883-90A
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English (en)
Slovak (sk)
Other versions
SK281179B6 (sk
Inventor
May Dean-Ming Lee
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of SK188390A3 publication Critical patent/SK188390A3/sk
Publication of SK281179B6 publication Critical patent/SK281179B6/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SK1883-90A 1989-04-14 1990-04-13 N-acylderiváty antibiotík ll-e33288, spôsoby ich prípravy a ich použitie na výrobu liečiv SK281179B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/338,928 US5079233A (en) 1987-01-30 1989-04-14 N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same

Publications (2)

Publication Number Publication Date
SK188390A3 true SK188390A3 (en) 2000-12-11
SK281179B6 SK281179B6 (sk) 2000-12-11

Family

ID=23326735

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1883-90A SK281179B6 (sk) 1989-04-14 1990-04-13 N-acylderiváty antibiotík ll-e33288, spôsoby ich prípravy a ich použitie na výrobu liečiv

Country Status (23)

Country Link
US (1) US5079233A (de)
EP (2) EP0392376B1 (de)
JP (1) JP3083309B2 (de)
KR (1) KR0149493B1 (de)
CN (1) CN1027267C (de)
AT (2) ATE297405T1 (de)
AU (1) AU627863B2 (de)
CA (1) CA2014472C (de)
CZ (2) CZ297668B6 (de)
DE (2) DE69034194T2 (de)
DK (2) DK1097937T3 (de)
ES (2) ES2162783T3 (de)
FI (1) FI97889C (de)
HK (2) HK1035540A1 (de)
IE (1) IE20011013A1 (de)
IL (1) IL93732A (de)
NO (1) NO172938C (de)
NZ (1) NZ233149A (de)
PH (1) PH27361A (de)
PT (1) PT93715B (de)
SG (1) SG47857A1 (de)
SK (1) SK281179B6 (de)
ZA (1) ZA902839B (de)

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NO901654L (no) 1990-10-15
AU5324890A (en) 1990-10-18
ES2240000T3 (es) 2005-10-16
NO901654D0 (no) 1990-04-11
CA2014472A1 (en) 1990-10-14
KR0149493B1 (ko) 1998-08-17
PH27361A (en) 1993-06-21
US5079233A (en) 1992-01-07
CZ188390A3 (cs) 1998-10-14
HK1011368A1 (en) 1999-07-09
AU627863B2 (en) 1992-09-03
FI97889B (fi) 1996-11-29
IL93732A (en) 1994-11-28
DK0392376T3 (da) 2001-12-03
FI901865A0 (fi) 1990-05-12
EP1097937A1 (de) 2001-05-09
FI97889C (fi) 1997-03-10
IL93732A0 (en) 1990-12-23
NZ233149A (en) 1996-02-27
DK1097937T3 (da) 2005-09-19
DE69034194D1 (de) 2005-07-14
SG47857A1 (en) 1998-04-17
DE69033839T2 (de) 2002-06-06
NO172938C (no) 1993-12-29
PT93715B (pt) 1996-08-30
JP3083309B2 (ja) 2000-09-04
EP0392376B1 (de) 2001-10-31
CN1027267C (zh) 1995-01-04
EP0392376A2 (de) 1990-10-17
CZ284618B6 (cs) 1999-01-13
CZ297668B6 (cs) 2007-02-28
EP1097937B1 (de) 2005-06-08
PT93715A (pt) 1990-11-20
CZ53598A3 (cs) 1998-09-16
DE69033839D1 (de) 2001-12-06
ATE297405T1 (de) 2005-06-15
EP0392376A3 (de) 1991-08-14
DE69034194T2 (de) 2005-11-03
HK1035540A1 (en) 2001-11-30
CA2014472C (en) 2000-03-28
CN1048390A (zh) 1991-01-09
NO172938B (no) 1993-06-21
ZA902839B (en) 1991-12-24
ES2162783T3 (es) 2002-01-16
JPH032192A (ja) 1991-01-08
KR900016242A (ko) 1990-11-13
SK281179B6 (sk) 2000-12-11
IE20011013A1 (en) 2002-12-30
ATE207926T1 (de) 2001-11-15

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