ATE297405T1 - N-acylderivate der antitumor-antibiotika vom typ ll-e33288 - Google Patents

N-acylderivate der antitumor-antibiotika vom typ ll-e33288

Info

Publication number
ATE297405T1
ATE297405T1 AT00128100T AT00128100T ATE297405T1 AT E297405 T1 ATE297405 T1 AT E297405T1 AT 00128100 T AT00128100 T AT 00128100T AT 00128100 T AT00128100 T AT 00128100T AT E297405 T1 ATE297405 T1 AT E297405T1
Authority
AT
Austria
Prior art keywords
type
acyl derivatives
antitumor antibiotics
acyl
antitumor
Prior art date
Application number
AT00128100T
Other languages
English (en)
Inventor
May Dean-Ming Lee
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE297405T1 publication Critical patent/ATE297405T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29Micromonospora

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT00128100T 1989-04-14 1990-04-06 N-acylderivate der antitumor-antibiotika vom typ ll-e33288 ATE297405T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/338,928 US5079233A (en) 1987-01-30 1989-04-14 N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same

Publications (1)

Publication Number Publication Date
ATE297405T1 true ATE297405T1 (de) 2005-06-15

Family

ID=23326735

Family Applications (2)

Application Number Title Priority Date Filing Date
AT90106601T ATE207926T1 (de) 1989-04-14 1990-04-06 N-acylderivate der antitumor-antibiotika vom typ ll-e33288
AT00128100T ATE297405T1 (de) 1989-04-14 1990-04-06 N-acylderivate der antitumor-antibiotika vom typ ll-e33288

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT90106601T ATE207926T1 (de) 1989-04-14 1990-04-06 N-acylderivate der antitumor-antibiotika vom typ ll-e33288

Country Status (23)

Country Link
US (1) US5079233A (de)
EP (2) EP1097937B1 (de)
JP (1) JP3083309B2 (de)
KR (1) KR0149493B1 (de)
CN (1) CN1027267C (de)
AT (2) ATE207926T1 (de)
AU (1) AU627863B2 (de)
CA (1) CA2014472C (de)
CZ (2) CZ284618B6 (de)
DE (2) DE69033839T2 (de)
DK (2) DK0392376T3 (de)
ES (2) ES2162783T3 (de)
FI (1) FI97889C (de)
HK (2) HK1011368A1 (de)
IE (1) IE20011013A1 (de)
IL (1) IL93732A (de)
NO (1) NO172938C (de)
NZ (1) NZ233149A (de)
PH (1) PH27361A (de)
PT (1) PT93715B (de)
SG (1) SG47857A1 (de)
SK (1) SK281179B6 (de)
ZA (1) ZA902839B (de)

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SK188390A3 (en) 2000-12-11
US5079233A (en) 1992-01-07
DK1097937T3 (da) 2005-09-19
HK1035540A1 (en) 2001-11-30
CN1048390A (zh) 1991-01-09
DE69034194T2 (de) 2005-11-03
IL93732A0 (en) 1990-12-23
CA2014472C (en) 2000-03-28
DE69033839D1 (de) 2001-12-06
EP0392376A2 (de) 1990-10-17
NO172938C (no) 1993-12-29
FI901865A0 (fi) 1990-05-12
CZ188390A3 (cs) 1998-10-14
CA2014472A1 (en) 1990-10-14
KR900016242A (ko) 1990-11-13
DE69033839T2 (de) 2002-06-06
PT93715B (pt) 1996-08-30
NO901654L (no) 1990-10-15
NO901654D0 (no) 1990-04-11
JP3083309B2 (ja) 2000-09-04
CN1027267C (zh) 1995-01-04
DK0392376T3 (da) 2001-12-03
AU627863B2 (en) 1992-09-03
SG47857A1 (en) 1998-04-17
FI97889C (fi) 1997-03-10
EP1097937A1 (de) 2001-05-09
CZ284618B6 (cs) 1999-01-13
NO172938B (no) 1993-06-21
IE20011013A1 (en) 2002-12-30
ES2162783T3 (es) 2002-01-16
EP0392376A3 (de) 1991-08-14
FI97889B (fi) 1996-11-29
IL93732A (en) 1994-11-28
PH27361A (en) 1993-06-21
CZ297668B6 (cs) 2007-02-28
EP1097937B1 (de) 2005-06-08
ZA902839B (en) 1991-12-24
ATE207926T1 (de) 2001-11-15
AU5324890A (en) 1990-10-18
ES2240000T3 (es) 2005-10-16
NZ233149A (en) 1996-02-27
EP0392376B1 (de) 2001-10-31
JPH032192A (ja) 1991-01-08
CZ53598A3 (cs) 1998-09-16
KR0149493B1 (ko) 1998-08-17
PT93715A (pt) 1990-11-20
SK281179B6 (sk) 2000-12-11
HK1011368A1 (en) 1999-07-09
DE69034194D1 (de) 2005-07-14

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