ZA836538B - Dichloro derivatives of the 16alpha-methyl pregnane series,their preparation,their use as medicaments and the compositions containing them - Google Patents
Dichloro derivatives of the 16alpha-methyl pregnane series,their preparation,their use as medicaments and the compositions containing themInfo
- Publication number
- ZA836538B ZA836538B ZA836538A ZA836538A ZA836538B ZA 836538 B ZA836538 B ZA 836538B ZA 836538 A ZA836538 A ZA 836538A ZA 836538 A ZA836538 A ZA 836538A ZA 836538 B ZA836538 B ZA 836538B
- Authority
- ZA
- South Africa
- Prior art keywords
- 16alpha
- medicaments
- preparation
- compositions containing
- pregnane series
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/13—Monohydroxylic alcohols containing saturated rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C68/00—Preparation of esters of carbonic or haloformic acids
- C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
- C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
- C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8216668A FR2533928A1 (fr) | 1982-10-05 | 1982-10-05 | Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA836538B true ZA836538B (en) | 1984-10-31 |
Family
ID=9277977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA836538A ZA836538B (en) | 1982-10-05 | 1983-09-03 | Dichloro derivatives of the 16alpha-methyl pregnane series,their preparation,their use as medicaments and the compositions containing them |
Country Status (22)
Country | Link |
---|---|
US (1) | US4515787A (fr) |
JP (1) | JPS59116300A (fr) |
AT (1) | AT385996B (fr) |
AU (1) | AU563739B2 (fr) |
BE (1) | BE897906A (fr) |
CA (1) | CA1203234A (fr) |
CH (1) | CH659251A5 (fr) |
DE (1) | DE3336292A1 (fr) |
DK (1) | DK164062C (fr) |
ES (1) | ES526212A0 (fr) |
FI (1) | FI77668C (fr) |
FR (1) | FR2533928A1 (fr) |
GB (1) | GB2127827B (fr) |
HU (1) | HU190506B (fr) |
IE (1) | IE56022B1 (fr) |
IT (1) | IT1197713B (fr) |
MA (1) | MA19909A1 (fr) |
NL (1) | NL8303409A (fr) |
NO (1) | NO157864C (fr) |
OA (1) | OA07558A (fr) |
SE (1) | SE447388B (fr) |
ZA (1) | ZA836538B (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2561919B1 (fr) * | 1984-04-03 | 1986-12-19 | Roussel Uclaf | Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon |
GB8512738D0 (en) * | 1984-09-04 | 1985-06-26 | Gen Electric | Silylation method |
DE69942578D1 (de) | 1998-05-22 | 2010-08-26 | Univ R | Bifunktionelle moleküle sowie darauf basierende therapien. |
US7247607B2 (en) * | 2001-11-08 | 2007-07-24 | Green & Clean, Inc. | Active soluble cleaning composite of natural state using soybean fatty acids and the making method thereof |
EP2671508B1 (fr) | 2005-04-28 | 2020-09-16 | Proteus Digital Health, Inc. | Système pharma-informatique |
JP2009508494A (ja) | 2005-09-16 | 2009-03-05 | ラプトール ファーマシューティカル インコーポレイテッド | Crを含むタンパク質に対して特異的な受容体−結合タンパク質(rap)変異体を含む組成物およびその使用 |
CA2969926C (fr) | 2009-02-20 | 2018-05-15 | 2-Bbb Medicines B.V. | Systeme d'administration de medicament a base de glutathionne |
EP4218718A3 (fr) | 2009-05-06 | 2024-04-24 | Laboratory Skin Care, Inc. | Compositions pour libération dermique comprenant des complexes principe actif-particule de phosphate de calcium et procédés d'utilisation associés |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2342738A1 (fr) * | 1976-03-02 | 1977-09-30 | Roussel Uclaf | Nouveaux derives halogenes de la serie du 16a-methyl pregnane |
FR2381065A2 (fr) * | 1977-02-22 | 1978-09-15 | Roussel Uclaf | Nouveaux derives halogenes de la serie du 16 a-methyl pregnane |
FR2462443A1 (fr) * | 1979-07-26 | 1981-02-13 | Roussel Uclaf | Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament |
-
1982
- 1982-10-05 FR FR8216668A patent/FR2533928A1/fr active Granted
-
1983
- 1983-07-20 SE SE8304062A patent/SE447388B/sv not_active IP Right Cessation
- 1983-07-27 NO NO832738A patent/NO157864C/no unknown
- 1983-09-03 ZA ZA836538A patent/ZA836538B/xx unknown
- 1983-09-15 US US06/532,739 patent/US4515787A/en not_active Expired - Fee Related
- 1983-09-19 IT IT48990/83A patent/IT1197713B/it active
- 1983-09-28 MA MA20132A patent/MA19909A1/fr unknown
- 1983-09-30 AU AU19824/83A patent/AU563739B2/en not_active Ceased
- 1983-10-04 CH CH5395/83A patent/CH659251A5/fr not_active IP Right Cessation
- 1983-10-04 DK DK456483A patent/DK164062C/da not_active IP Right Cessation
- 1983-10-04 ES ES526212A patent/ES526212A0/es active Granted
- 1983-10-04 FI FI833602A patent/FI77668C/fi not_active IP Right Cessation
- 1983-10-04 BE BE0/211641A patent/BE897906A/fr not_active IP Right Cessation
- 1983-10-04 HU HU833444A patent/HU190506B/hu not_active IP Right Cessation
- 1983-10-04 GB GB08326527A patent/GB2127827B/en not_active Expired
- 1983-10-04 IE IE2337/83A patent/IE56022B1/en not_active IP Right Cessation
- 1983-10-04 CA CA000438264A patent/CA1203234A/fr not_active Expired
- 1983-10-05 JP JP58185211A patent/JPS59116300A/ja active Granted
- 1983-10-05 AT AT0352783A patent/AT385996B/de not_active IP Right Cessation
- 1983-10-05 DE DE19833336292 patent/DE3336292A1/de active Granted
- 1983-10-05 OA OA58129A patent/OA07558A/fr unknown
- 1983-10-05 NL NL8303409A patent/NL8303409A/nl not_active Application Discontinuation
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