ES526212A0 - Un procedimiento de preparacion de nuevos derivados diclorados de la serie 16- -metil-pregnano - Google Patents

Un procedimiento de preparacion de nuevos derivados diclorados de la serie 16- -metil-pregnano

Info

Publication number
ES526212A0
ES526212A0 ES526212A ES526212A ES526212A0 ES 526212 A0 ES526212 A0 ES 526212A0 ES 526212 A ES526212 A ES 526212A ES 526212 A ES526212 A ES 526212A ES 526212 A0 ES526212 A0 ES 526212A0
Authority
ES
Spain
Prior art keywords
dichlorated
pregnano
metil
derivatives
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES526212A
Other languages
English (en)
Other versions
ES8405812A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES526212A0 publication Critical patent/ES526212A0/es
Publication of ES8405812A1 publication Critical patent/ES8405812A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/13Monohydroxylic alcohols containing saturated rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00Preparation of esters of carbonic or haloformic acids
    • C07C68/02Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
ES526212A 1982-10-05 1983-10-04 Un procedimiento de preparacion de nuevos derivados diclorados de la serie 16- -metil-pregnano Expired ES8405812A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8216668A FR2533928A1 (fr) 1982-10-05 1982-10-05 Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
ES526212A0 true ES526212A0 (es) 1984-06-16
ES8405812A1 ES8405812A1 (es) 1984-06-16

Family

ID=9277977

Family Applications (1)

Application Number Title Priority Date Filing Date
ES526212A Expired ES8405812A1 (es) 1982-10-05 1983-10-04 Un procedimiento de preparacion de nuevos derivados diclorados de la serie 16- -metil-pregnano

Country Status (22)

Country Link
US (1) US4515787A (es)
JP (1) JPS59116300A (es)
AT (1) AT385996B (es)
AU (1) AU563739B2 (es)
BE (1) BE897906A (es)
CA (1) CA1203234A (es)
CH (1) CH659251A5 (es)
DE (1) DE3336292A1 (es)
DK (1) DK164062C (es)
ES (1) ES8405812A1 (es)
FI (1) FI77668C (es)
FR (1) FR2533928A1 (es)
GB (1) GB2127827B (es)
HU (1) HU190506B (es)
IE (1) IE56022B1 (es)
IT (1) IT1197713B (es)
MA (1) MA19909A1 (es)
NL (1) NL8303409A (es)
NO (1) NO157864C (es)
OA (1) OA07558A (es)
SE (1) SE447388B (es)
ZA (1) ZA836538B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2561919B1 (fr) * 1984-04-03 1986-12-19 Roussel Uclaf Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon
GB8512738D0 (en) * 1984-09-04 1985-06-26 Gen Electric Silylation method
WO1999061055A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
US7247607B2 (en) * 2001-11-08 2007-07-24 Green & Clean, Inc. Active soluble cleaning composite of natural state using soybean fatty acids and the making method thereof
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
TR201908314T4 (tr) 2009-02-20 2019-06-21 2 Bbb Medicines B V Glutatyon bazlı ilaç dağıtım sistemi.
IL295075A (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2342738A1 (fr) * 1976-03-02 1977-09-30 Roussel Uclaf Nouveaux derives halogenes de la serie du 16a-methyl pregnane
FR2381065A2 (fr) * 1977-02-22 1978-09-15 Roussel Uclaf Nouveaux derives halogenes de la serie du 16 a-methyl pregnane
FR2462443A1 (fr) * 1979-07-26 1981-02-13 Roussel Uclaf Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament

Also Published As

Publication number Publication date
AU563739B2 (en) 1987-07-23
NL8303409A (nl) 1984-05-01
US4515787A (en) 1985-05-07
FI77668C (fi) 1989-04-10
AT385996B (de) 1988-06-10
OA07558A (fr) 1985-03-31
ES8405812A1 (es) 1984-06-16
FR2533928B1 (es) 1985-05-03
DE3336292C2 (es) 1992-09-10
IT1197713B (it) 1988-12-06
ZA836538B (en) 1984-10-31
BE897906A (fr) 1984-04-04
FR2533928A1 (fr) 1984-04-06
CH659251A5 (fr) 1987-01-15
GB8326527D0 (en) 1983-11-02
FI833602A (fi) 1984-04-06
CA1203234A (fr) 1986-04-15
SE8304062D0 (sv) 1983-07-20
JPS59116300A (ja) 1984-07-05
IE56022B1 (en) 1991-03-27
HU190506B (en) 1986-09-29
DK456483A (da) 1984-04-06
DE3336292A1 (de) 1984-04-05
NO832738L (no) 1984-04-06
FI77668B (fi) 1988-12-30
ATA352783A (de) 1987-11-15
DK164062C (da) 1992-09-28
NO157864B (no) 1988-02-22
AU1982483A (en) 1984-04-12
DK164062B (da) 1992-05-04
DK456483D0 (da) 1983-10-04
GB2127827B (en) 1986-01-29
FI833602A0 (fi) 1983-10-04
MA19909A1 (fr) 1984-04-01
NO157864C (no) 1988-06-01
GB2127827A (en) 1984-04-18
SE8304062L (sv) 1984-04-06
IE832337L (en) 1984-04-05
JPH0412279B2 (es) 1992-03-04
SE447388B (sv) 1986-11-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519