SE8304062D0 - Nouveaux derives dichlores de la serie du 16 alfa-methyl pregnane, leur preparation, leur application comme medicaments et les compositions les renfermant - Google Patents
Nouveaux derives dichlores de la serie du 16 alfa-methyl pregnane, leur preparation, leur application comme medicaments et les compositions les renfermantInfo
- Publication number
- SE8304062D0 SE8304062D0 SE8304062A SE8304062A SE8304062D0 SE 8304062 D0 SE8304062 D0 SE 8304062D0 SE 8304062 A SE8304062 A SE 8304062A SE 8304062 A SE8304062 A SE 8304062A SE 8304062 D0 SE8304062 D0 SE 8304062D0
- Authority
- SE
- Sweden
- Prior art keywords
- leur
- les
- dichlores
- serie
- alfa
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- TXTGPWLZHZYCQV-YFOXLAJYSA-N (8s,9s,10s,13r,14s,17s)-10,13-dimethyl-17-propyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthrene Chemical compound C1CC2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](CCC)[C@@]1(C)CC2 TXTGPWLZHZYCQV-YFOXLAJYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- -1 trimethylsilylphenyl Chemical group 0.000 abstract 2
- QIEPWCSVQYUPIY-LEKSSAKUSA-N Delta(1)-progesterone Chemical class C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 QIEPWCSVQYUPIY-LEKSSAKUSA-N 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000000062 cyclohexylmethoxy group Chemical group [H]C([H])(O*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/13—Monohydroxylic alcohols containing saturated rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C68/00—Preparation of esters of carbonic or haloformic acids
- C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
- C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
- C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Rheumatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8216668A FR2533928A1 (fr) | 1982-10-05 | 1982-10-05 | Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8304062D0 true SE8304062D0 (sv) | 1983-07-20 |
| SE8304062L SE8304062L (sv) | 1984-04-06 |
| SE447388B SE447388B (sv) | 1986-11-10 |
Family
ID=9277977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8304062A SE447388B (sv) | 1982-10-05 | 1983-07-20 | Nya diklorerade derivat av 16-alfa-metylpregnanserien, framstellning derav,anvendning derav som lekemedel och kompositioner innehallande dem |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4515787A (sv) |
| JP (1) | JPS59116300A (sv) |
| AT (1) | AT385996B (sv) |
| AU (1) | AU563739B2 (sv) |
| BE (1) | BE897906A (sv) |
| CA (1) | CA1203234A (sv) |
| CH (1) | CH659251A5 (sv) |
| DE (1) | DE3336292A1 (sv) |
| DK (1) | DK164062C (sv) |
| ES (1) | ES526212A0 (sv) |
| FI (1) | FI77668C (sv) |
| FR (1) | FR2533928A1 (sv) |
| GB (1) | GB2127827B (sv) |
| HU (1) | HU190506B (sv) |
| IE (1) | IE56022B1 (sv) |
| IT (1) | IT1197713B (sv) |
| MA (1) | MA19909A1 (sv) |
| NL (1) | NL8303409A (sv) |
| NO (1) | NO157864C (sv) |
| OA (1) | OA07558A (sv) |
| SE (1) | SE447388B (sv) |
| ZA (1) | ZA836538B (sv) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2561919B1 (fr) * | 1984-04-03 | 1986-12-19 | Roussel Uclaf | Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon |
| GB8512738D0 (en) * | 1984-09-04 | 1985-06-26 | Gen Electric | Silylation method |
| ATE473759T1 (de) | 1998-05-22 | 2010-07-15 | Univ Leland Stanford Junior | Bifunktionelle moleküle sowie darauf basierende therapien. |
| US7247607B2 (en) * | 2001-11-08 | 2007-07-24 | Green & Clean, Inc. | Active soluble cleaning composite of natural state using soybean fatty acids and the making method thereof |
| CN103259027A (zh) | 2005-04-28 | 2013-08-21 | 普罗透斯数字保健公司 | 药物信息系统 |
| JP2009508494A (ja) | 2005-09-16 | 2009-03-05 | ラプトール ファーマシューティカル インコーポレイテッド | Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用 |
| PT2398500T (pt) | 2009-02-20 | 2019-06-14 | 2 Bbb Medicines B V | Sistema de entrega de medicamentos à base de glutationas |
| TWI556839B (zh) | 2009-05-06 | 2016-11-11 | 研究室護膚股份有限公司 | 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2342738A1 (fr) * | 1976-03-02 | 1977-09-30 | Roussel Uclaf | Nouveaux derives halogenes de la serie du 16a-methyl pregnane |
| FR2381065A2 (fr) * | 1977-02-22 | 1978-09-15 | Roussel Uclaf | Nouveaux derives halogenes de la serie du 16 a-methyl pregnane |
| FR2462443A1 (fr) * | 1979-07-26 | 1981-02-13 | Roussel Uclaf | Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament |
-
1982
- 1982-10-05 FR FR8216668A patent/FR2533928A1/fr active Granted
-
1983
- 1983-07-20 SE SE8304062A patent/SE447388B/sv not_active IP Right Cessation
- 1983-07-27 NO NO832738A patent/NO157864C/no unknown
- 1983-09-03 ZA ZA836538A patent/ZA836538B/xx unknown
- 1983-09-15 US US06/532,739 patent/US4515787A/en not_active Expired - Fee Related
- 1983-09-19 IT IT48990/83A patent/IT1197713B/it active
- 1983-09-28 MA MA20132A patent/MA19909A1/fr unknown
- 1983-09-30 AU AU19824/83A patent/AU563739B2/en not_active Ceased
- 1983-10-04 BE BE0/211641A patent/BE897906A/fr not_active IP Right Cessation
- 1983-10-04 ES ES526212A patent/ES526212A0/es active Granted
- 1983-10-04 DK DK456483A patent/DK164062C/da not_active IP Right Cessation
- 1983-10-04 CH CH5395/83A patent/CH659251A5/fr not_active IP Right Cessation
- 1983-10-04 IE IE2337/83A patent/IE56022B1/en not_active IP Right Cessation
- 1983-10-04 GB GB08326527A patent/GB2127827B/en not_active Expired
- 1983-10-04 FI FI833602A patent/FI77668C/sv not_active IP Right Cessation
- 1983-10-04 HU HU833444A patent/HU190506B/hu not_active IP Right Cessation
- 1983-10-04 CA CA000438264A patent/CA1203234A/fr not_active Expired
- 1983-10-05 JP JP58185211A patent/JPS59116300A/ja active Granted
- 1983-10-05 NL NL8303409A patent/NL8303409A/nl not_active Application Discontinuation
- 1983-10-05 OA OA58129A patent/OA07558A/xx unknown
- 1983-10-05 AT AT0352783A patent/AT385996B/de not_active IP Right Cessation
- 1983-10-05 DE DE19833336292 patent/DE3336292A1/de active Granted
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE8300308D0 (sv) | Nouveaux derives de 3-ceto delta 4,9 19-nor-steroides, leur preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus | |
| DE3762412D1 (de) | (meth)acrylsaeureester und ihre verwendung zur herstellung von dentalmassen. | |
| FR2603037B1 (fr) | (pentamethyl-1,2,2,6,6,6 piperidyl-4 amino)- triazines, leur application comme stabilisants de matieres organiques, et compositions qui en contiennent | |
| SE8304062D0 (sv) | Nouveaux derives dichlores de la serie du 16 alfa-methyl pregnane, leur preparation, leur application comme medicaments et les compositions les renfermant | |
| FR2643638B1 (fr) | Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant | |
| FR2533929B1 (fr) | Ester methylique de l'acide 25, 26, 27 -trinor-1a, 2b-epoxy-cholesta-4,6-diene-3-one-24-oique | |
| MA19882A1 (fr) | Derives d'acides w-amines, leur preparation et utilisation ainsi que les compositions contenant ces acides. | |
| IL57691A (en) | Delta-4,9-gonadiene-21-ol-3,20-diones,process for preparing them and pharmaceutical compositions containing them | |
| ATE90355T1 (de) | Weiche steroide mit anti-entzuendungswirkung. | |
| FR2567884B1 (fr) | Nouveaux derives de l'indole, leur preparation, leur application comme medicaments et les compositions les renfermant | |
| OA06889A (fr) | Nouveaux dérivés du 4H-1,2,4-triazole, leur préparation, leur application comme médicament, les compositions les renfermant et les intermédiaires obtenus. | |
| OA07539A (fr) | Nouveaux dérivés d'acides phényl aliphatiques, leur préparation, leur application comme médicaments, et les compositions les renfermant. | |
| BE893957A (fr) | Steroides esterifies en la position 17 et thio-esterifies en la position 21,leur procede de preparation et leur application comme medicament. | |
| BE896941A (fr) | Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires obtenues | |
| BE872908A (fr) | Compositions pharmaceutiques pour le traitement de l'hypertension | |
| BE877658A (fr) | Nouveaux derives acetyleniques de l'androst-4-ene, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant | |
| BE878256A (fr) | Nouveaux derives acetyleniques de l'androst-4-ene, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant | |
| TR199900725T2 (xx) | Hidroksamik asit t�revleri | |
| DK146785A (da) | Pharmaceutisk praeparat med indhold af 9alfa, 11beta-dichlor-16alfa-methyl-21-oxycarbonyldicyclohexylmethyloxypregna-1,4-dien-3,20-dion | |
| BE879739A (fr) | Procede perfectionne de preparation de compositions d'hydrocarbures phosphosulfures contenant du molybdene | |
| FR2518537B1 (fr) | Nouveaux derives de l'acide phenylacetique, leur preparation et compositions les contenant | |
| TR21618A (tr) | Metilen-2 sueksinamik asid'in yeni tuerevleri bunlarin hazirlanmasi ve bunlari ihtiva oden bitkilerin yetismesini duezenleyici bilesimler | |
| BE891744A (fr) | Nouveaux derives de l'acide cephalosporanique, leur preparation et leur application comme medicaments | |
| IT8347633A0 (it) | Aspirapolvere con dispositivo per migliorare l'odore dell'aria ambiente | |
| BE893576A (fr) | Nouveaux derives de l'acide cephalosporanique leur preparation et leur application comme medecaments |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 8304062-6 Effective date: 19950210 Format of ref document f/p: F |
|
| NUG | Patent has lapsed |
Ref document number: 8304062-6 Format of ref document f/p: F |