OA07558A - Nouveaux dérivés dichlorés de la série du 16@- méthyl pregnane, leur préparation, leur application comme médicaments et les compositions les renfermant. - Google Patents

Nouveaux dérivés dichlorés de la série du 16@- méthyl pregnane, leur préparation, leur application comme médicaments et les compositions les renfermant.

Info

Publication number
OA07558A
OA07558A OA58129A OA58129A OA07558A OA 07558 A OA07558 A OA 07558A OA 58129 A OA58129 A OA 58129A OA 58129 A OA58129 A OA 58129A OA 07558 A OA07558 A OA 07558A
Authority
OA
OAPI
Prior art keywords
medicaments
preparation
new
application
compositions containing
Prior art date
Application number
OA58129A
Other languages
English (en)
Inventor
Teutsch Jean Georges
Deraedt Roger
Benzoni Josette
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of OA07558A publication Critical patent/OA07558A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/13—Monohydroxylic alcohols containing saturated rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
OA58129A 1982-10-05 1983-10-05 Nouveaux dérivés dichlorés de la série du 16@- méthyl pregnane, leur préparation, leur application comme médicaments et les compositions les renfermant. OA07558A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8216668A FR2533928A1 (fr) 1982-10-05 1982-10-05 Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
OA07558A true OA07558A (fr) 1985-03-31

Family

ID=9277977

Family Applications (1)

Application Number Title Priority Date Filing Date
OA58129A OA07558A (fr) 1982-10-05 1983-10-05 Nouveaux dérivés dichlorés de la série du 16@- méthyl pregnane, leur préparation, leur application comme médicaments et les compositions les renfermant.

Country Status (22)

Country Link
US (1) US4515787A (fr)
JP (1) JPS59116300A (fr)
AT (1) AT385996B (fr)
AU (1) AU563739B2 (fr)
BE (1) BE897906A (fr)
CA (1) CA1203234A (fr)
CH (1) CH659251A5 (fr)
DE (1) DE3336292A1 (fr)
DK (1) DK164062C (fr)
ES (1) ES8405812A1 (fr)
FI (1) FI77668C (fr)
FR (1) FR2533928A1 (fr)
GB (1) GB2127827B (fr)
HU (1) HU190506B (fr)
IE (1) IE56022B1 (fr)
IT (1) IT1197713B (fr)
MA (1) MA19909A1 (fr)
NL (1) NL8303409A (fr)
NO (1) NO157864C (fr)
OA (1) OA07558A (fr)
SE (1) SE447388B (fr)
ZA (1) ZA836538B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2561919B1 (fr) * 1984-04-03 1986-12-19 Roussel Uclaf Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon
GB8512738D0 (en) * 1984-09-04 1985-06-26 Gen Electric Silylation method
US6372712B1 (en) 1998-05-22 2002-04-16 The Board Of Trustees Of The Leland Stanford Jr. University Synthetic bifunctional molecules containing a drug moiety and presenter protein ligand
US7247607B2 (en) * 2001-11-08 2007-07-24 Green & Clean, Inc. Active soluble cleaning composite of natural state using soybean fatty acids and the making method thereof
EP3827747A1 (fr) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Système pharma-informatique
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
EP3395372B1 (fr) 2009-02-20 2022-04-06 EnhanX Biopharm Inc. Système d'administration de médicament à base de glutathion
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2342738A1 (fr) * 1976-03-02 1977-09-30 Roussel Uclaf Nouveaux derives halogenes de la serie du 16a-methyl pregnane
FR2381065A2 (fr) * 1977-02-22 1978-09-15 Roussel Uclaf Nouveaux derives halogenes de la serie du 16 a-methyl pregnane
FR2462443A1 (fr) * 1979-07-26 1981-02-13 Roussel Uclaf Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament

Also Published As

Publication number Publication date
DK164062C (da) 1992-09-28
ES526212A0 (es) 1984-06-16
ZA836538B (en) 1984-10-31
IE56022B1 (en) 1991-03-27
DE3336292C2 (fr) 1992-09-10
FI77668B (fi) 1988-12-30
AU1982483A (en) 1984-04-12
NO832738L (no) 1984-04-06
SE8304062L (sv) 1984-04-06
FI77668C (fi) 1989-04-10
DK164062B (da) 1992-05-04
DK456483D0 (da) 1983-10-04
ATA352783A (de) 1987-11-15
SE8304062D0 (sv) 1983-07-20
IT1197713B (it) 1988-12-06
ES8405812A1 (es) 1984-06-16
DE3336292A1 (de) 1984-04-05
DK456483A (da) 1984-04-06
AU563739B2 (en) 1987-07-23
JPS59116300A (ja) 1984-07-05
CA1203234A (fr) 1986-04-15
HU190506B (en) 1986-09-29
FR2533928B1 (fr) 1985-05-03
GB8326527D0 (en) 1983-11-02
FR2533928A1 (fr) 1984-04-06
NL8303409A (nl) 1984-05-01
NO157864B (no) 1988-02-22
GB2127827B (en) 1986-01-29
AT385996B (de) 1988-06-10
CH659251A5 (fr) 1987-01-15
US4515787A (en) 1985-05-07
NO157864C (no) 1988-06-01
BE897906A (fr) 1984-04-04
FI833602A0 (fi) 1983-10-04
SE447388B (sv) 1986-11-10
FI833602A (fi) 1984-04-06
IE832337L (en) 1984-04-05
GB2127827A (en) 1984-04-18
MA19909A1 (fr) 1984-04-01
JPH0412279B2 (fr) 1992-03-04

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