FR2342738A1 - Nouveaux derives halogenes de la serie du 16a-methyl pregnane - Google Patents

Nouveaux derives halogenes de la serie du 16a-methyl pregnane

Info

Publication number
FR2342738A1
FR2342738A1 FR7605854A FR7605854A FR2342738A1 FR 2342738 A1 FR2342738 A1 FR 2342738A1 FR 7605854 A FR7605854 A FR 7605854A FR 7605854 A FR7605854 A FR 7605854A FR 2342738 A1 FR2342738 A1 FR 2342738A1
Authority
FR
France
Prior art keywords
halogen derivatives
pregnane series
new halogen
methyl pregnane
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7605854A
Other languages
English (en)
Other versions
FR2342738B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7605854A priority Critical patent/FR2342738A1/fr
Priority to ZA00771078A priority patent/ZA771078B/xx
Priority to JP2039977A priority patent/JPS52106855A/ja
Priority to CA272,894A priority patent/CA1082170A/fr
Priority to AU22808/77A priority patent/AU509948B2/en
Priority to SE7702250A priority patent/SE7702250L/
Priority to NL7702166A priority patent/NL7702166A/xx
Priority to DK088277A priority patent/DK156401C/da
Priority to BE175355A priority patent/BE851944A/fr
Priority to AT136577A priority patent/AT355237B/de
Priority to LU76867A priority patent/LU76867A1/xx
Priority to PT66261A priority patent/PT66261B/fr
Priority to CH264177A priority patent/CH619969A5/fr
Priority to IE462/77A priority patent/IE44866B1/en
Priority to GB8713/77A priority patent/GB1530975A/en
Priority to DE2709078A priority patent/DE2709078C2/de
Publication of FR2342738A1 publication Critical patent/FR2342738A1/fr
Application granted granted Critical
Publication of FR2342738B1 publication Critical patent/FR2342738B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7605854A 1976-03-02 1976-03-02 Nouveaux derives halogenes de la serie du 16a-methyl pregnane Granted FR2342738A1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR7605854A FR2342738A1 (fr) 1976-03-02 1976-03-02 Nouveaux derives halogenes de la serie du 16a-methyl pregnane
ZA00771078A ZA771078B (en) 1976-03-02 1977-02-23 New halogenated derivatives of the 16a-methyl pregnane series,process for preparing them and pharmaceutical compositions
JP2039977A JPS52106855A (en) 1976-03-02 1977-02-28 Novel halogenated derivatives of 16 alphaamethypregnane * preparation thereof and pharmaceutical composition
AT136577A AT355237B (de) 1976-03-02 1977-03-01 Verfahren zur herstellung neuer halogenderivate in der reihe des 16 alpha- methylpregnans
SE7702250A SE7702250L (sv) 1976-03-02 1977-03-01 Sett att framstella nya halogenderivat i 16alfa-metylpregnanserien
NL7702166A NL7702166A (nl) 1976-03-02 1977-03-01 Werkwijze voor de bereiding van 16(alpha)-methylpreg- naan-derivaten en van preparaten die ze bevat- ten.
DK088277A DK156401C (da) 1976-03-02 1977-03-01 Analogifremgangsmaade til fremstilling af halogenderivater af 16 alpha-methyl-pregnanraekken
BE175355A BE851944A (fr) 1976-03-02 1977-03-01 Nouveaux derives halogenes de la serie du 16-methyl pregnane
CA272,894A CA1082170A (fr) 1976-03-02 1977-03-01 Procede de preparation de nouveau derives halogenes de la serie du 16 .alpha.-methyl pregnane
LU76867A LU76867A1 (fr) 1976-03-02 1977-03-01
AU22808/77A AU509948B2 (en) 1976-03-02 1977-03-01 Halogenated derivatives of 16 alphamethyl pregnant
PT66261A PT66261B (fr) 1976-03-02 1977-03-02 Serie du 16alpha-methyl pregnane procede de preparation de nouveaux derives halogenes de la
CH264177A CH619969A5 (en) 1976-03-02 1977-03-02 Process for the preparation of new halogenated derivatives of the 16alpha-methylpregnane series
IE462/77A IE44866B1 (en) 1976-03-02 1977-03-02 New halogenated derivatives of the 16a-methylpregnane series,processes for preparing them and pharmaceutical compositions containing them
GB8713/77A GB1530975A (en) 1976-03-02 1977-03-02 Halogenated derivatives of the 16alpha-methylpregnane series processes for preparing them and pharmaceutical compositions containing them
DE2709078A DE2709078C2 (de) 1976-03-02 1977-03-02 Neue Halogen-Derivate der Reihe des 16α-Methylpregnans, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7605854A FR2342738A1 (fr) 1976-03-02 1976-03-02 Nouveaux derives halogenes de la serie du 16a-methyl pregnane

Publications (2)

Publication Number Publication Date
FR2342738A1 true FR2342738A1 (fr) 1977-09-30
FR2342738B1 FR2342738B1 (fr) 1979-10-12

Family

ID=9169832

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7605854A Granted FR2342738A1 (fr) 1976-03-02 1976-03-02 Nouveaux derives halogenes de la serie du 16a-methyl pregnane

Country Status (16)

Country Link
JP (1) JPS52106855A (fr)
AT (1) AT355237B (fr)
AU (1) AU509948B2 (fr)
BE (1) BE851944A (fr)
CA (1) CA1082170A (fr)
CH (1) CH619969A5 (fr)
DE (1) DE2709078C2 (fr)
DK (1) DK156401C (fr)
FR (1) FR2342738A1 (fr)
GB (1) GB1530975A (fr)
IE (1) IE44866B1 (fr)
LU (1) LU76867A1 (fr)
NL (1) NL7702166A (fr)
PT (1) PT66261B (fr)
SE (1) SE7702250L (fr)
ZA (1) ZA771078B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2462443A1 (fr) * 1979-07-26 1981-02-13 Roussel Uclaf Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament
DE3336292A1 (de) * 1982-10-05 1984-04-05 Roussel-Uclaf, 75007 Paris Neue dichlorderivate der 16(alpha)-methylpregnanreihe, deren herstellung, deren verwendung als arzneimittel und die sie enthaltenden zusammensetzungen

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4433374A1 (de) * 1994-09-20 1996-03-21 Hoechst Ag 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB928302A (en) * 1958-06-20 1963-06-12 Scherico Ltd í¸-pregnene compounds
US3049554A (en) * 1959-06-01 1962-08-14 Schering Corp 9, 11-dihalogeno-3, 20-diketopregnanes and processes for their manufacture

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2462443A1 (fr) * 1979-07-26 1981-02-13 Roussel Uclaf Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament
DE3028255A1 (de) * 1979-07-26 1981-02-19 Roussel Uclaf Neues halogen-derivat aus der 16 alpha -methylpregnan-reihe, seine herstellung, seine verwendung als arzneimittel und die es enthaltenden zusammensetzungen
US4353899A (en) * 1979-07-26 1982-10-12 Roussel Uclaf Novel 16α-methyl-pregnane
DE3336292A1 (de) * 1982-10-05 1984-04-05 Roussel-Uclaf, 75007 Paris Neue dichlorderivate der 16(alpha)-methylpregnanreihe, deren herstellung, deren verwendung als arzneimittel und die sie enthaltenden zusammensetzungen
FR2533928A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
AT355237B (de) 1980-02-25
DE2709078C2 (de) 1986-09-11
BE851944A (fr) 1977-09-01
PT66261B (fr) 1979-01-17
ATA136577A (de) 1979-07-15
JPS6150960B2 (fr) 1986-11-06
ZA771078B (en) 1978-04-26
GB1530975A (en) 1978-11-01
IE44866B1 (en) 1982-04-21
AU509948B2 (en) 1980-06-05
FR2342738B1 (fr) 1979-10-12
DK88277A (da) 1977-09-03
AU2280877A (en) 1978-09-07
CA1082170A (fr) 1980-07-22
DE2709078A1 (de) 1977-09-08
DK156401B (da) 1989-08-14
SE7702250L (sv) 1977-09-03
NL7702166A (nl) 1977-09-06
CH619969A5 (en) 1980-10-31
DK156401C (da) 1990-01-08
JPS52106855A (en) 1977-09-07
PT66261A (fr) 1977-04-01
IE44866L (en) 1977-09-02
LU76867A1 (fr) 1977-09-26

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Legal Events

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