JPS52106855A - Novel halogenated derivatives of 16 alphaamethypregnane * preparation thereof and pharmaceutical composition - Google Patents

Novel halogenated derivatives of 16 alphaamethypregnane * preparation thereof and pharmaceutical composition

Info

Publication number
JPS52106855A
JPS52106855A JP2039977A JP2039977A JPS52106855A JP S52106855 A JPS52106855 A JP S52106855A JP 2039977 A JP2039977 A JP 2039977A JP 2039977 A JP2039977 A JP 2039977A JP S52106855 A JPS52106855 A JP S52106855A
Authority
JP
Japan
Prior art keywords
alphaamethypregnane
preparation
pharmaceutical composition
halogenated derivatives
novel halogenated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2039977A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6150960B2 (fr
Inventor
Jiyorujiyu Touuchi Jiyan
Kosutoruusu Jieruman
Dorae Rojie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS52106855A publication Critical patent/JPS52106855A/ja
Publication of JPS6150960B2 publication Critical patent/JPS6150960B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
JP2039977A 1976-03-02 1977-02-28 Novel halogenated derivatives of 16 alphaamethypregnane * preparation thereof and pharmaceutical composition Granted JPS52106855A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7605854A FR2342738A1 (fr) 1976-03-02 1976-03-02 Nouveaux derives halogenes de la serie du 16a-methyl pregnane

Publications (2)

Publication Number Publication Date
JPS52106855A true JPS52106855A (en) 1977-09-07
JPS6150960B2 JPS6150960B2 (fr) 1986-11-06

Family

ID=9169832

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2039977A Granted JPS52106855A (en) 1976-03-02 1977-02-28 Novel halogenated derivatives of 16 alphaamethypregnane * preparation thereof and pharmaceutical composition

Country Status (16)

Country Link
JP (1) JPS52106855A (fr)
AT (1) AT355237B (fr)
AU (1) AU509948B2 (fr)
BE (1) BE851944A (fr)
CA (1) CA1082170A (fr)
CH (1) CH619969A5 (fr)
DE (1) DE2709078C2 (fr)
DK (1) DK156401C (fr)
FR (1) FR2342738A1 (fr)
GB (1) GB1530975A (fr)
IE (1) IE44866B1 (fr)
LU (1) LU76867A1 (fr)
NL (1) NL7702166A (fr)
PT (1) PT66261B (fr)
SE (1) SE7702250L (fr)
ZA (1) ZA771078B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2462443A1 (fr) * 1979-07-26 1981-02-13 Roussel Uclaf Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament
FR2533928A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments
DE4433374A1 (de) * 1994-09-20 1996-03-21 Hoechst Ag 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB928301A (en) * 1958-06-20 1963-06-12 Scherico Ltd 9, 11-dihalogeno steroids
US3049554A (en) * 1959-06-01 1962-08-14 Schering Corp 9, 11-dihalogeno-3, 20-diketopregnanes and processes for their manufacture

Also Published As

Publication number Publication date
JPS6150960B2 (fr) 1986-11-06
BE851944A (fr) 1977-09-01
SE7702250L (sv) 1977-09-03
PT66261B (fr) 1979-01-17
IE44866L (en) 1977-09-02
DK88277A (da) 1977-09-03
GB1530975A (en) 1978-11-01
NL7702166A (nl) 1977-09-06
ZA771078B (en) 1978-04-26
AT355237B (de) 1980-02-25
DK156401B (da) 1989-08-14
ATA136577A (de) 1979-07-15
DE2709078A1 (de) 1977-09-08
LU76867A1 (fr) 1977-09-26
FR2342738A1 (fr) 1977-09-30
CH619969A5 (en) 1980-10-31
AU509948B2 (en) 1980-06-05
FR2342738B1 (fr) 1979-10-12
AU2280877A (en) 1978-09-07
DE2709078C2 (de) 1986-09-11
IE44866B1 (en) 1982-04-21
PT66261A (fr) 1977-04-01
CA1082170A (fr) 1980-07-22
DK156401C (da) 1990-01-08

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