FR2343727A1 - Nouveaux derives du cholesterol - Google Patents

Nouveaux derives du cholesterol

Info

Publication number
FR2343727A1
FR2343727A1 FR7706407A FR7706407A FR2343727A1 FR 2343727 A1 FR2343727 A1 FR 2343727A1 FR 7706407 A FR7706407 A FR 7706407A FR 7706407 A FR7706407 A FR 7706407A FR 2343727 A1 FR2343727 A1 FR 2343727A1
Authority
FR
France
Prior art keywords
cholesterol
new derivatives
derivatives
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7706407A
Other languages
English (en)
Other versions
FR2343727B1 (fr
Inventor
Enrico Baggiolini
John Joseph Partridge Jr
Milan Radoje Uskokovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/664,848 external-priority patent/US4026882A/en
Priority claimed from US05/664,799 external-priority patent/US4021423A/en
Priority claimed from US05/664,833 external-priority patent/US4028349A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2343727A1 publication Critical patent/FR2343727A1/fr
Application granted granted Critical
Publication of FR2343727B1 publication Critical patent/FR2343727B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7706407A 1976-03-08 1977-03-04 Nouveaux derives du cholesterol Granted FR2343727A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/664,848 US4026882A (en) 1976-03-08 1976-03-08 Syntheses of 3,24R,25- and 3,24S,25-trihydroxy-5,7-cholestadiene 24,25-ketals and alkanoyl derivatives thereof
US05/664,799 US4021423A (en) 1976-03-08 1976-03-08 Syntheses of 24R,25- and 24S,25-dihydroxycholecalciferol
US05/664,833 US4028349A (en) 1976-03-08 1976-03-08 Syntheses of 24R,25- and 24S,25-dihydroxycholesterol 24,25-ketals and alkanoyl derivatives thereof

Publications (2)

Publication Number Publication Date
FR2343727A1 true FR2343727A1 (fr) 1977-10-07
FR2343727B1 FR2343727B1 (fr) 1984-01-13

Family

ID=27418118

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7706407A Granted FR2343727A1 (fr) 1976-03-08 1977-03-04 Nouveaux derives du cholesterol

Country Status (7)

Country Link
JP (1) JPS52108960A (fr)
CH (4) CH626336A5 (fr)
DE (1) DE2710062A1 (fr)
FR (1) FR2343727A1 (fr)
GB (1) GB1572952A (fr)
IT (1) IT1078064B (fr)
NL (1) NL7702484A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063678A2 (fr) * 1981-04-29 1982-11-03 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Procédé de préparation de dérivés du cholestérol et composés intermédiaires

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5735599A (en) * 1980-08-05 1982-02-26 Chugai Pharmaceut Co Ltd 24,25-dihydroxycholestane and its preparation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1178427B (de) * 1961-01-26 1964-09-24 Olin Mathieson Verfahren zur Herstellung von 16ª‡, 17ª‡-Dihydroxysteroiden der Pregnanreihe
US3715374A (en) * 1972-05-05 1973-02-06 Wisconsin Alumni Res Found 24,25-dihydroxycholecalciferol
FR2213053A1 (fr) * 1973-01-10 1974-08-02 Res Inst Medicine Chemistry

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51128417A (en) * 1975-04-28 1976-11-09 Teijin Ltd A method for stabilizing active vitamin d3 derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1178427B (de) * 1961-01-26 1964-09-24 Olin Mathieson Verfahren zur Herstellung von 16ª‡, 17ª‡-Dihydroxysteroiden der Pregnanreihe
US3715374A (en) * 1972-05-05 1973-02-06 Wisconsin Alumni Res Found 24,25-dihydroxycholecalciferol
FR2213053A1 (fr) * 1973-01-10 1974-08-02 Res Inst Medicine Chemistry

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/75 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063678A2 (fr) * 1981-04-29 1982-11-03 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Procédé de préparation de dérivés du cholestérol et composés intermédiaires
EP0063678A3 (en) * 1981-04-29 1983-01-12 F. Hoffmann-La Roche & Co. Aktiengesellschaft Process for the preparation of cholesterol derivatives, and intermediate derivatives therefor

Also Published As

Publication number Publication date
FR2343727B1 (fr) 1984-01-13
NL7702484A (nl) 1977-09-12
JPS52108960A (en) 1977-09-12
IT1078064B (it) 1985-05-08
CH627764A5 (en) 1982-01-29
CH627192A5 (en) 1981-12-31
DE2710062A1 (de) 1977-09-15
CH626336A5 (en) 1981-11-13
CH627159A5 (en) 1981-12-31
GB1572952A (en) 1980-08-06

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Legal Events

Date Code Title Description
ST Notification of lapse