FI833602A - Foerfarande foer framstaellning av nya 16 -metylpregnanseriens diklorderivat - Google Patents

Foerfarande foer framstaellning av nya 16 -metylpregnanseriens diklorderivat Download PDF

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Publication number
FI833602A
FI833602A FI833602A FI833602A FI833602A FI 833602 A FI833602 A FI 833602A FI 833602 A FI833602 A FI 833602A FI 833602 A FI833602 A FI 833602A FI 833602 A FI833602 A FI 833602A
Authority
FI
Finland
Prior art keywords
pregnancy
detergent
methyl
determination
methyl pregnancy
Prior art date
Application number
FI833602A
Other languages
English (en)
Other versions
FI833602A0 (fi
FI77668B (fi
FI77668C (fi
Inventor
Jean Georges Teutsch
Roger Deraedt
Josette Benzoni
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI833602A0 publication Critical patent/FI833602A0/fi
Publication of FI833602A publication Critical patent/FI833602A/fi
Publication of FI77668B publication Critical patent/FI77668B/fi
Application granted granted Critical
Publication of FI77668C publication Critical patent/FI77668C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/13Monohydroxylic alcohols containing saturated rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00Preparation of esters of carbonic or haloformic acids
    • C07C68/02Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI833602A 1982-10-05 1983-10-04 Foerfarande foer framstaellning av nya 16 -metyl-pregnanseriens diklorderivat. FI77668C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8216668 1982-10-05
FR8216668A FR2533928A1 (fr) 1982-10-05 1982-10-05 Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments

Publications (4)

Publication Number Publication Date
FI833602A0 FI833602A0 (fi) 1983-10-04
FI833602A true FI833602A (fi) 1984-04-06
FI77668B FI77668B (fi) 1988-12-30
FI77668C FI77668C (fi) 1989-04-10

Family

ID=9277977

Family Applications (1)

Application Number Title Priority Date Filing Date
FI833602A FI77668C (fi) 1982-10-05 1983-10-04 Foerfarande foer framstaellning av nya 16 -metyl-pregnanseriens diklorderivat.

Country Status (22)

Country Link
US (1) US4515787A (fi)
JP (1) JPS59116300A (fi)
AT (1) AT385996B (fi)
AU (1) AU563739B2 (fi)
BE (1) BE897906A (fi)
CA (1) CA1203234A (fi)
CH (1) CH659251A5 (fi)
DE (1) DE3336292A1 (fi)
DK (1) DK164062C (fi)
ES (1) ES8405812A1 (fi)
FI (1) FI77668C (fi)
FR (1) FR2533928A1 (fi)
GB (1) GB2127827B (fi)
HU (1) HU190506B (fi)
IE (1) IE56022B1 (fi)
IT (1) IT1197713B (fi)
MA (1) MA19909A1 (fi)
NL (1) NL8303409A (fi)
NO (1) NO157864C (fi)
OA (1) OA07558A (fi)
SE (1) SE447388B (fi)
ZA (1) ZA836538B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2561919B1 (fr) * 1984-04-03 1986-12-19 Roussel Uclaf Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon
GB8512738D0 (en) * 1984-09-04 1985-06-26 Gen Electric Silylation method
AU4093799A (en) 1998-05-22 1999-12-13 Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
US7247607B2 (en) * 2001-11-08 2007-07-24 Green & Clean, Inc. Active soluble cleaning composite of natural state using soybean fatty acids and the making method thereof
JP2008539047A (ja) 2005-04-28 2008-11-13 プロテウス バイオメディカル インコーポレイテッド ファーマインフォーマティックスシステム
WO2007035716A2 (en) 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2342738A1 (fr) * 1976-03-02 1977-09-30 Roussel Uclaf Nouveaux derives halogenes de la serie du 16a-methyl pregnane
FR2381065A2 (fr) * 1977-02-22 1978-09-15 Roussel Uclaf Nouveaux derives halogenes de la serie du 16 a-methyl pregnane
FR2462443A1 (fr) * 1979-07-26 1981-02-13 Roussel Uclaf Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament

Also Published As

Publication number Publication date
GB2127827B (en) 1986-01-29
FI833602A0 (fi) 1983-10-04
HU190506B (en) 1986-09-29
ES526212A0 (es) 1984-06-16
BE897906A (fr) 1984-04-04
MA19909A1 (fr) 1984-04-01
FR2533928B1 (fi) 1985-05-03
FI77668B (fi) 1988-12-30
GB2127827A (en) 1984-04-18
DK164062B (da) 1992-05-04
DK456483D0 (da) 1983-10-04
FI77668C (fi) 1989-04-10
DE3336292A1 (de) 1984-04-05
DK164062C (da) 1992-09-28
DK456483A (da) 1984-04-06
SE447388B (sv) 1986-11-10
CA1203234A (fr) 1986-04-15
IT1197713B (it) 1988-12-06
NO157864B (no) 1988-02-22
NL8303409A (nl) 1984-05-01
AT385996B (de) 1988-06-10
GB8326527D0 (en) 1983-11-02
JPS59116300A (ja) 1984-07-05
DE3336292C2 (fi) 1992-09-10
ES8405812A1 (es) 1984-06-16
AU563739B2 (en) 1987-07-23
NO832738L (no) 1984-04-06
SE8304062L (sv) 1984-04-06
CH659251A5 (fr) 1987-01-15
ZA836538B (en) 1984-10-31
IE56022B1 (en) 1991-03-27
AU1982483A (en) 1984-04-12
NO157864C (no) 1988-06-01
SE8304062D0 (sv) 1983-07-20
OA07558A (fr) 1985-03-31
IE832337L (en) 1984-04-05
JPH0412279B2 (fi) 1992-03-04
ATA352783A (de) 1987-11-15
FR2533928A1 (fr) 1984-04-06
US4515787A (en) 1985-05-07

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MM Patent lapsed
MM Patent lapsed

Owner name: ROUSSEL UCLAF SOCIETE ANONYME