ZA201000085B - 2-oxo-3-benzyl-benzoxazol-2-one derivatives and related compounds as Met kinase inhibitors for the treatment of tumors - Google Patents

2-oxo-3-benzyl-benzoxazol-2-one derivatives and related compounds as Met kinase inhibitors for the treatment of tumors

Info

Publication number
ZA201000085B
ZA201000085B ZA201000085A ZA201000085A ZA201000085B ZA 201000085 B ZA201000085 B ZA 201000085B ZA 201000085 A ZA201000085 A ZA 201000085A ZA 201000085 A ZA201000085 A ZA 201000085A ZA 201000085 B ZA201000085 B ZA 201000085B
Authority
ZA
South Africa
Prior art keywords
benzoxazol
tumors
oxo
benzyl
derivatives
Prior art date
Application number
ZA201000085A
Other languages
English (en)
Inventor
Oliver Schadt
Dieter Dorsch
Frank Stieber
Andree Blaukat
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA201000085B publication Critical patent/ZA201000085B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA201000085A 2007-06-06 2010-01-05 2-oxo-3-benzyl-benzoxazol-2-one derivatives and related compounds as Met kinase inhibitors for the treatment of tumors ZA201000085B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102007026341A DE102007026341A1 (de) 2007-06-06 2007-06-06 Benzoxazolonderivate

Publications (1)

Publication Number Publication Date
ZA201000085B true ZA201000085B (en) 2010-09-29

Family

ID=39739806

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA201000085A ZA201000085B (en) 2007-06-06 2010-01-05 2-oxo-3-benzyl-benzoxazol-2-one derivatives and related compounds as Met kinase inhibitors for the treatment of tumors

Country Status (18)

Country Link
US (2) US8071593B2 (enExample)
EP (1) EP2150551B1 (enExample)
JP (1) JP5662143B2 (enExample)
KR (1) KR20100031531A (enExample)
CN (1) CN101679401B (enExample)
AR (1) AR066892A1 (enExample)
AU (1) AU2008258366B2 (enExample)
BR (1) BRPI0812293A2 (enExample)
CA (1) CA2689554C (enExample)
DE (1) DE102007026341A1 (enExample)
EA (1) EA200901611A1 (enExample)
ES (1) ES2402540T3 (enExample)
IL (1) IL202505A (enExample)
MX (1) MX2009013077A (enExample)
PE (1) PE20090770A1 (enExample)
TW (1) TW200848030A (enExample)
WO (1) WO2008148449A1 (enExample)
ZA (1) ZA201000085B (enExample)

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Also Published As

Publication number Publication date
IL202505A0 (en) 2010-06-30
ES2402540T3 (es) 2013-05-06
EP2150551A1 (de) 2010-02-10
WO2008148449A1 (de) 2008-12-11
AR066892A1 (es) 2009-09-16
US8431572B2 (en) 2013-04-30
CA2689554C (en) 2015-12-01
PE20090770A1 (es) 2009-06-24
CN101679401B (zh) 2012-12-12
CN101679401A (zh) 2010-03-24
JP5662143B2 (ja) 2015-01-28
IL202505A (en) 2014-11-30
BRPI0812293A2 (pt) 2014-11-25
AU2008258366B2 (en) 2013-02-21
US20100280030A1 (en) 2010-11-04
US8071593B2 (en) 2011-12-06
EP2150551B1 (de) 2013-01-16
KR20100031531A (ko) 2010-03-22
CA2689554A1 (en) 2008-12-11
AU2008258366A1 (en) 2008-12-11
JP2010529051A (ja) 2010-08-26
TW200848030A (en) 2008-12-16
EA200901611A1 (ru) 2010-06-30
US20110263596A1 (en) 2011-10-27
MX2009013077A (es) 2010-01-15
DE102007026341A1 (de) 2008-12-11

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