IL202505A - 2-oxo-3-benzyl-benzoxazole-2-one derivatives and related compounds as met kinase inhibitors for the treatment of tumors, drugs containing them and their uses - Google Patents

2-oxo-3-benzyl-benzoxazole-2-one derivatives and related compounds as met kinase inhibitors for the treatment of tumors, drugs containing them and their uses

Info

Publication number
IL202505A
IL202505A IL202505A IL20250509A IL202505A IL 202505 A IL202505 A IL 202505A IL 202505 A IL202505 A IL 202505A IL 20250509 A IL20250509 A IL 20250509A IL 202505 A IL202505 A IL 202505A
Authority
IL
Israel
Prior art keywords
benzoxazol
medicaments
tumors
oxo
benzyl
Prior art date
Application number
IL202505A
Other languages
English (en)
Hebrew (he)
Other versions
IL202505A0 (en
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IL202505A0 publication Critical patent/IL202505A0/en
Publication of IL202505A publication Critical patent/IL202505A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL202505A 2007-06-06 2009-12-03 2-oxo-3-benzyl-benzoxazole-2-one derivatives and related compounds as met kinase inhibitors for the treatment of tumors, drugs containing them and their uses IL202505A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007026341A DE102007026341A1 (de) 2007-06-06 2007-06-06 Benzoxazolonderivate
PCT/EP2008/003696 WO2008148449A1 (de) 2007-06-06 2008-05-08 2-oxo-3-benzyl-benzoxazol-2-one derivate und verwandte verbindungen als met-kinase inhibitoren zur behandlung von tumoren

Publications (2)

Publication Number Publication Date
IL202505A0 IL202505A0 (en) 2010-06-30
IL202505A true IL202505A (en) 2014-11-30

Family

ID=39739806

Family Applications (1)

Application Number Title Priority Date Filing Date
IL202505A IL202505A (en) 2007-06-06 2009-12-03 2-oxo-3-benzyl-benzoxazole-2-one derivatives and related compounds as met kinase inhibitors for the treatment of tumors, drugs containing them and their uses

Country Status (18)

Country Link
US (2) US8071593B2 (enExample)
EP (1) EP2150551B1 (enExample)
JP (1) JP5662143B2 (enExample)
KR (1) KR20100031531A (enExample)
CN (1) CN101679401B (enExample)
AR (1) AR066892A1 (enExample)
AU (1) AU2008258366B2 (enExample)
BR (1) BRPI0812293A2 (enExample)
CA (1) CA2689554C (enExample)
DE (1) DE102007026341A1 (enExample)
EA (1) EA200901611A1 (enExample)
ES (1) ES2402540T3 (enExample)
IL (1) IL202505A (enExample)
MX (1) MX2009013077A (enExample)
PE (1) PE20090770A1 (enExample)
TW (1) TW200848030A (enExample)
WO (1) WO2008148449A1 (enExample)
ZA (1) ZA201000085B (enExample)

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WO2016135041A1 (en) 2015-02-26 2016-09-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Fusion proteins and antibodies comprising thereof for promoting apoptosis
KR101798840B1 (ko) 2017-05-17 2017-11-17 주식회사 레고켐 바이오사이언스 신규 오토탁신 저해 화합물 및 이를 함유하는 약제학적 조성물
JP2020524718A (ja) * 2017-06-22 2020-08-20 キュラデブ・ファーマ・リミテッドＣｕｒａｄｅｖ Ｐｈａｒｍａ Ｌｉｍｉｔｅｄ ヒトｓｔｉｎｇの複素環式小分子調節因子
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CN115490578B (zh) * 2022-09-23 2023-12-22 江苏理工学院 一种碳同位素标记的三氯生的制备方法

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Also Published As

Publication number Publication date
EP2150551B1 (de) 2013-01-16
CA2689554C (en) 2015-12-01
EA200901611A1 (ru) 2010-06-30
EP2150551A1 (de) 2010-02-10
AU2008258366A1 (en) 2008-12-11
AR066892A1 (es) 2009-09-16
DE102007026341A1 (de) 2008-12-11
AU2008258366B2 (en) 2013-02-21
BRPI0812293A2 (pt) 2014-11-25
MX2009013077A (es) 2010-01-15
WO2008148449A1 (de) 2008-12-11
CN101679401A (zh) 2010-03-24
ES2402540T3 (es) 2013-05-06
CN101679401B (zh) 2012-12-12
US20100280030A1 (en) 2010-11-04
ZA201000085B (en) 2010-09-29
CA2689554A1 (en) 2008-12-11
US8071593B2 (en) 2011-12-06
JP2010529051A (ja) 2010-08-26
US20110263596A1 (en) 2011-10-27
JP5662143B2 (ja) 2015-01-28
US8431572B2 (en) 2013-04-30
TW200848030A (en) 2008-12-16
KR20100031531A (ko) 2010-03-22
IL202505A0 (en) 2010-06-30
PE20090770A1 (es) 2009-06-24

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