PL2331092T3 - Sposoby i kompozycje do podawania 3-halopirogronianiu i związków pochodnych w leczeniu nowotworu - Google Patents

Sposoby i kompozycje do podawania 3-halopirogronianiu i związków pochodnych w leczeniu nowotworu

Info

Publication number
PL2331092T3
PL2331092T3 PL09808532T PL09808532T PL2331092T3 PL 2331092 T3 PL2331092 T3 PL 2331092T3 PL 09808532 T PL09808532 T PL 09808532T PL 09808532 T PL09808532 T PL 09808532T PL 2331092 T3 PL2331092 T3 PL 2331092T3
Authority
PL
Poland
Prior art keywords
halopyruvate
cancer
administration
compositions
treatment
Prior art date
Application number
PL09808532T
Other languages
English (en)
Inventor
Jean-Francois Geschwind
Mustafa Vali
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41707605&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2331092(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of PL2331092T3 publication Critical patent/PL2331092T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL09808532T 2008-08-21 2009-08-21 Sposoby i kompozycje do podawania 3-halopirogronianiu i związków pochodnych w leczeniu nowotworu PL2331092T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9079308P 2008-08-21 2008-08-21
US9740808P 2008-09-16 2008-09-16
US16523909P 2009-03-31 2009-03-31
PCT/US2009/004789 WO2010021750A2 (en) 2008-08-21 2009-08-21 Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer
EP09808532.7A EP2331092B1 (en) 2008-08-21 2009-08-21 Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer

Publications (1)

Publication Number Publication Date
PL2331092T3 true PL2331092T3 (pl) 2014-08-29

Family

ID=41707605

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09808532T PL2331092T3 (pl) 2008-08-21 2009-08-21 Sposoby i kompozycje do podawania 3-halopirogronianiu i związków pochodnych w leczeniu nowotworu

Country Status (6)

Country Link
US (2) US9492417B2 (pl)
EP (1) EP2331092B1 (pl)
DK (1) DK2331092T3 (pl)
ES (1) ES2464729T3 (pl)
PL (1) PL2331092T3 (pl)
WO (1) WO2010021750A2 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2331092T3 (pl) 2008-08-21 2014-08-29 Univ Johns Hopkins Sposoby i kompozycje do podawania 3-halopirogronianiu i związków pochodnych w leczeniu nowotworu
WO2013103840A1 (en) * 2012-01-05 2013-07-11 Guilford Frederick Timothy Anti-cancer composition and method utilizing 3-bp and liposomal reduced glutathione
CN106102725A (zh) * 2014-01-14 2016-11-09 约翰斯·霍普金斯大学 包封选择性atp抑制剂的环糊精组合物及其应用
EP3370712B1 (en) 2015-11-06 2025-02-19 The Johns Hopkins University 3-bromopyruvate for treating liver fibrosis
WO2020152487A1 (en) 2018-11-13 2020-07-30 The Nielsen Compy (Us), Llc Methods and apparatus to perform image analyses in a computing environment
WO2024119187A1 (en) * 2022-12-02 2024-06-06 Kodiscovery, Llc Heavy isotope 3-bp molecules, compositions, and treatments

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4337760A (en) * 1978-10-13 1982-07-06 Adolf Schwimmer Method for the treatment of tumors with β-glucuronidase activity dependent pharmaceuticals
EP0086627B1 (en) * 1982-02-12 1985-08-28 Unitika Ltd. Anti-cancer device
US4737323A (en) 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
US5800820A (en) * 1989-01-10 1998-09-01 Repligen Corporation Methods and compositions for treatment of angiogenic diseases
US5759837A (en) * 1989-01-17 1998-06-02 John Hopkins University Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
IT1263831B (it) 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina
ATE227979T1 (de) 1993-04-22 2002-12-15 Skyepharma Inc Multivesikuläre liposomen mit verkapseltem cyclodextrin und pharmakologisch wirksamen verbindungen sowie verfahren zu deren verwendung
HU213200B (en) 1993-05-12 1997-03-28 Chinoin Gyogyszer Es Vegyeszet The cyclodextrin or cyclodextrin derivative cluster complexes of taxol, taxotere, or taxus, pharmaceutical preparations containing them and process for their production
IL115849A0 (en) 1994-11-03 1996-01-31 Merz & Co Gmbh & Co Tangential filtration preparation of liposomal drugs and liposome product thereof
AU6676396A (en) 1995-07-14 1997-02-18 Johns Hopkins University, The Tumor type ii hexokinase transcription regulatory regions
US5854067A (en) * 1996-01-19 1998-12-29 Board Of Regents, The University Of Texas System Hexokinase inhibitors
US6312662B1 (en) * 1998-03-06 2001-11-06 Metabasis Therapeutics, Inc. Prodrugs phosphorus-containing compounds
US6214879B1 (en) * 1998-03-24 2001-04-10 Virginia Commonwealth University Allosteric inhibitors of pyruvate kinase
DE19814815C2 (de) 1998-04-02 2000-10-12 Gerhard Steffan Sterinverknüpfte, anionische Cyclodextrinderivate und deren Verwendung in Arzneimittelformulierungen
US6284786B1 (en) * 1999-02-16 2001-09-04 The Center For The Improvement Of Human Functioning, Int'l., Inc. Treatment of cancer using lipoic acid in combination with ascorbic acid
US20020006915A1 (en) * 2000-02-15 2002-01-17 Mack Strong Vivian E. Use of COX-2 inhibitors to treat sepsis, complications thereof, and EP receptor modulation
US6448030B1 (en) * 2000-02-18 2002-09-10 University Of Nevada-Las Vegas Method for predicting the efficacy of anti-cancer drugs
AU2001245766A1 (en) * 2000-03-14 2001-09-24 The Johns Hopkins University School Of Medicine Arrest of proliferation of highly glycolytic tumors
US6670330B1 (en) * 2000-05-01 2003-12-30 Theodore J. Lampidis Cancer chemotherapy with 2-deoxy-D-glucose
WO2002033118A2 (en) * 2000-08-03 2002-04-25 The Texas A & M University System Isocitrate lyase enzyme from mycobacterium tuberculosis and inhibitory agents to combat persistent infection
US7381713B2 (en) * 2000-12-04 2008-06-03 Sioan-Kettering Institute For Cancer Research Treatment of cancer by reduction of intracellular energy and pyrimidines
US7547673B2 (en) * 2001-09-13 2009-06-16 The Johns Hopkins University Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production
JP2005534718A (ja) 2002-06-26 2005-11-17 メディゲーネ オンコロギー ゲゼルシャフト ミット ベシュレンクテル ハフツング カチオンキャリヤー系において診断化合物および治療化合物を安定化させる新規方法
EP1526865A4 (en) * 2002-08-05 2009-09-02 Mirus Bio Corp COMPOUNDS FOR TARGETING HEPATIC CELLS
AU2004204778B2 (en) * 2003-01-10 2008-05-22 Threshold Pharmaceuticals, Inc. Treatment of cancer with 2-deoxyglucose
EP1610778A4 (en) * 2003-01-17 2006-05-31 Threshold Pharmaceuticals Inc TREATMENT OF BENIGNER PROSTATE HYPERPLASIA
UA80743C2 (en) 2003-02-26 2007-10-25 Boehringer Ingelheim Pharma Dihydropteridinones, method for the production and use thereof in the form of drugs
UA86063C2 (ru) 2004-05-03 2009-03-25 Хермес Біосайенсез, Інк. Липосомы для снабжения лекарств
WO2006010073A1 (en) * 2004-07-08 2006-01-26 Threshold Pharmaceuticals, Inc. Prevention of cancer
CA2575367A1 (en) 2004-07-28 2006-02-23 Board Of Regents, The University Of Texas System 3-halo-2-oxopropionate salts and esters as novel anticancer agents
US7754693B2 (en) * 2006-02-16 2010-07-13 Young Hee Ko Composition and method for the efficacious and safe administration of halopyruvate for the treatment of cancer
CN101951930A (zh) 2008-02-19 2011-01-19 阿奈斯特药品株式会社 对身体功能的恢复有用的口服或经肠组合物
PL2331092T3 (pl) 2008-08-21 2014-08-29 Univ Johns Hopkins Sposoby i kompozycje do podawania 3-halopirogronianiu i związków pochodnych w leczeniu nowotworu
JP5622719B2 (ja) 2009-03-30 2014-11-12 エーザイ・アール・アンド・ディー・マネジメント株式会社 リポソーム組成物の製造方法
JP2014506922A (ja) 2011-03-01 2014-03-20 ティーオー − ビービービー ホールディング ベスローテン フェンノートシャップ 難水溶性物質の高度なアクティブリポソームローディング
US20150337121A1 (en) 2012-06-26 2015-11-26 The Johns Hopkins University Multifunctional tunable biomaterials for tissue engineering
US20140220112A1 (en) 2013-02-01 2014-08-07 Zoneone Pharma, Inc. Transformation of drug cyclodextrin complex compositions into compositions of mixtures of lipid vesicle encapsulated drug and cyclodextrin drug complexes
CN106102725A (zh) 2014-01-14 2016-11-09 约翰斯·霍普金斯大学 包封选择性atp抑制剂的环糊精组合物及其应用

Also Published As

Publication number Publication date
EP2331092A4 (en) 2011-10-12
US20100137434A1 (en) 2010-06-03
US10130598B2 (en) 2018-11-20
WO2010021750A2 (en) 2010-02-25
US20170224641A1 (en) 2017-08-10
WO2010021750A3 (en) 2010-07-08
US9492417B2 (en) 2016-11-15
EP2331092A2 (en) 2011-06-15
ES2464729T3 (es) 2014-06-03
DK2331092T3 (da) 2014-05-19
EP2331092B1 (en) 2014-03-19

Similar Documents

Publication Publication Date Title
PL2340042T3 (pl) Sposoby i kompozycje do leczenia raka
PL2322221T3 (pl) Kompozycja farmaceutyczna do leczenia i zapobiegania raka
PL2200431T3 (pl) Nowe kompozycje i metody służące leczeniu raka
PT2303021T (pt) Compostos para tratamento do cancro
IL228597A0 (en) Isoindoline compounds for use in the treatment of cancer
IL225471A0 (en) Preparations and methods for the prevention and treatment of cancer
IL251083B (en) Compounds and preparations for the treatment of cancer
EP2211854A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER USING BENZOPYRONE-TYPE PARP INHIBITORS
IL206563A0 (en) Medicament for the treatment of cancer of the pancreas
IL214349A0 (en) Compositions and methods for the treatment of cancer
IL243294A0 (en) Compounds and compositions for the treatment of cancer
IL238394B (en) Preparations containing a combination of factors for the treatment of cancer
PL2305300T3 (pl) Kompozycja farmaceutyczna do leczenia i zapobiegania nowotworowi
PL2331092T3 (pl) Sposoby i kompozycje do podawania 3-halopirogronianiu i związków pochodnych w leczeniu nowotworu
IL206189A0 (en) Compound for use in the treatment of cancer
IL205339A0 (en) Compounds and methods for the treatment of cancer
GB0808326D0 (en) Compositions and methods for the treatment of fybromyalgia
AU2008903693A0 (en) Compositions and methods for the prevention and treatment of cancer
AU2008905198A0 (en) Compositions and Methods for the Prevention and Treatment of Cancer
HUE054409T2 (hu) Új kompozíciók és eljárások rák kezelésére
SI3067054T1 (sl) Novi sestavki in postopki za zdravljenje raka
IL221238A0 (en) Pharmaceutical compositions and methods for the treatment and prevention of cancer