ZA200502122B - Tetrahydropyrimidine-2-one derivatives and their uses - Google Patents
Tetrahydropyrimidine-2-one derivatives and their uses Download PDFInfo
- Publication number
- ZA200502122B ZA200502122B ZA200502122A ZA200502122A ZA200502122B ZA 200502122 B ZA200502122 B ZA 200502122B ZA 200502122 A ZA200502122 A ZA 200502122A ZA 200502122 A ZA200502122 A ZA 200502122A ZA 200502122 B ZA200502122 B ZA 200502122B
- Authority
- ZA
- South Africa
- Prior art keywords
- compound
- hydroxy
- tetrahydropyrimidine
- nitro
- formula
- Prior art date
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- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000002437 shaving preparation Substances 0.000 description 1
- 125000004469 siloxy group Chemical group [SiH3]O* 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- RAOIDOHSFRTOEL-UHFFFAOYSA-N tetrahydrothiophene Chemical compound C1CCSC1 RAOIDOHSFRTOEL-UHFFFAOYSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 125000004627 thianthrenyl group Chemical group C1(=CC=CC=2SC3=CC=CC=C3SC12)* 0.000 description 1
- AJZGFFKDLABHDD-UHFFFAOYSA-N thiazinane Chemical compound C1CCSNC1 AJZGFFKDLABHDD-UHFFFAOYSA-N 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 125000003866 trichloromethyl group Chemical group ClC(Cl)(Cl)* 0.000 description 1
- 210000000427 trigeminal ganglion Anatomy 0.000 description 1
- 238000002525 ultrasonication Methods 0.000 description 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 description 1
- PXXNTAGJWPJAGM-UHFFFAOYSA-N vertaline Natural products C1C2C=3C=C(OC)C(OC)=CC=3OC(C=C3)=CC=C3CCC(=O)OC1CC1N2CCCC1 PXXNTAGJWPJAGM-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 125000001834 xanthenyl group Chemical group C1=CC=CC=2OC3=CC=CC=C3C(C12)* 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/204—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/205—Heterocyclic compounds
- A23L27/2054—Heterocyclic compounds having nitrogen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
- A61K2800/244—Endothermic; Cooling; Cooling sensation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Seasonings (AREA)
- Confectionery (AREA)
- Seeds, Soups, And Other Foods (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0221697.6A GB0221697D0 (en) | 2002-09-18 | 2002-09-18 | Novel compouds and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200502122B true ZA200502122B (en) | 2006-05-31 |
Family
ID=9944340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200502122A ZA200502122B (en) | 2002-09-18 | 2005-03-14 | Tetrahydropyrimidine-2-one derivatives and their uses |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7045624B2 (pt) |
| EP (1) | EP1546114B1 (pt) |
| JP (1) | JP4959939B2 (pt) |
| CN (1) | CN100506800C (pt) |
| AU (1) | AU2003266321A1 (pt) |
| BR (1) | BR0314447A (pt) |
| GB (1) | GB0221697D0 (pt) |
| RU (1) | RU2334741C2 (pt) |
| WO (1) | WO2004026840A1 (pt) |
| ZA (1) | ZA200502122B (pt) |
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Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3821221A (en) * | 1970-08-25 | 1974-06-28 | Delmar Chem | 1,2,3,6-tetrahydropyrimidine-2-one compounds and processes for makingthem |
| JPH0887120A (ja) * | 1994-09-19 | 1996-04-02 | Fuji Electric Co Ltd | 電子写真用感光体 |
| CA2483090C (en) * | 2002-05-02 | 2011-01-25 | Cragmont Pharmaceuticals, Llc | Use of therapeutic 1,2,3,6-tetrahydropyrimidine-2-one compositions |
-
2002
- 2002-09-18 GB GBGB0221697.6A patent/GB0221697D0/en not_active Ceased
-
2003
- 2003-08-26 RU RU2005111243/04A patent/RU2334741C2/ru not_active IP Right Cessation
- 2003-08-26 AU AU2003266321A patent/AU2003266321A1/en not_active Abandoned
- 2003-08-26 EP EP03797254.4A patent/EP1546114B1/en not_active Expired - Lifetime
- 2003-08-26 JP JP2004536964A patent/JP4959939B2/ja not_active Expired - Fee Related
- 2003-08-26 CN CNB038251248A patent/CN100506800C/zh not_active Expired - Fee Related
- 2003-08-26 BR BR0314447-0A patent/BR0314447A/pt not_active Application Discontinuation
- 2003-08-26 WO PCT/EP2003/009566 patent/WO2004026840A1/en active Application Filing
- 2003-09-17 US US10/664,367 patent/US7045624B2/en not_active Expired - Fee Related
-
2005
- 2005-03-14 ZA ZA200502122A patent/ZA200502122B/en unknown
-
2006
- 2006-01-10 US US11/328,534 patent/US20060106217A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4959939B2 (ja) | 2012-06-27 |
| JP2006512294A (ja) | 2006-04-13 |
| CN100506800C (zh) | 2009-07-01 |
| AU2003266321A1 (en) | 2004-04-08 |
| US20060106217A1 (en) | 2006-05-18 |
| EP1546114B1 (en) | 2015-09-30 |
| CN1694872A (zh) | 2005-11-09 |
| US20040067970A1 (en) | 2004-04-08 |
| WO2004026840A1 (en) | 2004-04-01 |
| EP1546114A1 (en) | 2005-06-29 |
| RU2334741C2 (ru) | 2008-09-27 |
| GB0221697D0 (en) | 2002-10-30 |
| RU2005111243A (ru) | 2005-10-27 |
| US7045624B2 (en) | 2006-05-16 |
| BR0314447A (pt) | 2005-07-19 |
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