ZA200301097B - Water-dispersible encapsulated sterols. - Google Patents

Water-dispersible encapsulated sterols. Download PDF

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Publication number
ZA200301097B
ZA200301097B ZA200301097A ZA200301097A ZA200301097B ZA 200301097 B ZA200301097 B ZA 200301097B ZA 200301097 A ZA200301097 A ZA 200301097A ZA 200301097 A ZA200301097 A ZA 200301097A ZA 200301097 B ZA200301097 B ZA 200301097B
Authority
ZA
South Africa
Prior art keywords
starch
phytosterol
water
composition
surfactant
Prior art date
Application number
ZA200301097A
Other languages
English (en)
Inventor
Nicolas Auriou
Original Assignee
Novartis Nurtition Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Nurtition Ag filed Critical Novartis Nurtition Ag
Publication of ZA200301097B publication Critical patent/ZA200301097B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11Plant sterols or derivatives thereof, e.g. phytosterols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Dispersion Chemistry (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
ZA200301097A 2000-09-01 2003-02-10 Water-dispersible encapsulated sterols. ZA200301097B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0021498.1A GB0021498D0 (en) 2000-09-01 2000-09-01 New formulation

Publications (1)

Publication Number Publication Date
ZA200301097B true ZA200301097B (en) 2004-04-21

Family

ID=9898673

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200301097A ZA200301097B (en) 2000-09-01 2003-02-10 Water-dispersible encapsulated sterols.

Country Status (17)

Country Link
EP (2) EP1749520A1 (de)
JP (1) JP2004507492A (de)
AT (1) ATE345783T1 (de)
AU (1) AU2002213868A1 (de)
BR (1) BR0113621A (de)
CA (1) CA2419249A1 (de)
CY (1) CY1106039T1 (de)
DE (1) DE60124738T2 (de)
DK (1) DK1315482T3 (de)
ES (1) ES2277952T3 (de)
GB (1) GB0021498D0 (de)
HU (1) HUP0300878A3 (de)
MX (1) MXPA03001831A (de)
PL (1) PL359704A1 (de)
PT (1) PT1315482E (de)
WO (1) WO2002017892A2 (de)
ZA (1) ZA200301097B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6773733B2 (en) 2001-03-26 2004-08-10 Loders Croklaan Usa Llc Structured particulate systems
US6673383B2 (en) * 2001-03-26 2004-01-06 Unilever Patent Holdings Bv Method for improving the performance of a food product
US20030003131A1 (en) * 2001-06-22 2003-01-02 Matthew Dyer Method for manufacture of free-flowing powder containing water-dispersible sterols
US20060147523A1 (en) 2002-10-16 2006-07-06 Alan Fergusson Composition for the regulation of the human immune system and the prevention and treatment of diseases thereof
DE10253111A1 (de) * 2002-11-13 2004-05-27 Basf Ag Pulverförmige Phytosterol-Formulierungen
EP1661556A4 (de) * 2003-08-20 2010-05-19 Ajinomoto Kk Medizinisches präparat mit verbesserten auflösungseigenschaften
AU2004277906A1 (en) * 2003-09-22 2005-04-14 Degussa Health & Nutrition Americas, Inc. Incorporation of phytosterols into flavorings
US20070154557A1 (en) * 2004-01-30 2007-07-05 Veldhuizen Yvonne S J Particulate comprising phytosterols and food compositions comprising said creamer
US20050233002A1 (en) * 2004-04-15 2005-10-20 Trubiano Paolo C Encapsulation of oxygen sensitive agents
DE602004002763T2 (de) * 2004-06-04 2007-08-16 The Procter & Gamble Company, Cincinnati Verkapselte Partikel
US20060034934A1 (en) * 2004-08-13 2006-02-16 Deguise Matthew L Agglomeration of sterol particles
BRPI0514858B1 (pt) * 2004-09-02 2014-09-02 Quest International Services B.V. Composição flavorizante particulada, método de produzir a mesma, produto alimentício, e, processo de manufaturar o mesmo
JP4915717B2 (ja) * 2004-09-09 2012-04-11 花王株式会社 肥満予防・改善剤
JPWO2006095798A1 (ja) * 2005-03-09 2008-08-14 サンスター株式会社 フィトステロールを含んだリポソームを含有する抗癌用経口組成物、該リポソームによる癌の予防又は治療
US8309156B2 (en) 2005-12-20 2012-11-13 Pharmachem Laboratories, Inc. Compositions comprising one or more phytosterols and/or phytostanols, or derivatives thereof, and high HLB emulsifiers
CA2673010A1 (en) * 2005-12-20 2007-06-28 Forbes Medi-Tech Inc. Compositions comprising one or more phytosterols and/or phytostanols, or derivatives thereof, and high hlb emulsifiers
JP4989956B2 (ja) * 2006-12-11 2012-08-01 松谷化学工業株式会社 粉末化植物ステロールエステル製剤、その製造方法及びこれを含む飲食品
WO2009071289A1 (en) * 2007-12-05 2009-06-11 Dsm Ip Assets B.V. Pulverous formulation of a fat-soluble active ingredient
KR20100097664A (ko) * 2007-12-05 2010-09-03 디에스엠 아이피 어셋츠 비.브이. 지용성 활성 성분의 분말 제형
EP2067410A1 (de) 2007-12-07 2009-06-10 Cognis IP Management GmbH Wasser dispergierbares Sterol enthaltende Dispersion
WO2010093020A1 (ja) * 2009-02-13 2010-08-19 日新化成株式会社 硬カプセル
ES2374780A1 (es) * 2009-12-30 2012-02-22 José Javier Villa Cervera Procedimiento de fabricación de agua de beber, agua mineral, agua medicinal o similar, caracterizada porque incluye esteroles vegetales-fitoesteroles. la bebida contiene de 0.1 a 3 g litro de esteroles vegetales.
EA024947B1 (ru) 2010-12-28 2016-11-30 Юнилевер Нв Способ получения эмульсии
US20120282368A1 (en) * 2011-05-03 2012-11-08 Brandeis University Amphiphilic sterol/fat-based particles
JP6092579B2 (ja) * 2012-11-07 2017-03-08 理研ビタミン株式会社 粉末状植物ステロール組成物およびその製造方法
WO2014073542A1 (ja) * 2012-11-07 2014-05-15 理研ビタミン株式会社 粉末状植物ステロール組成物およびその製造方法
JP6092580B2 (ja) * 2012-11-07 2017-03-08 理研ビタミン株式会社 粉末状植物ステロール組成物およびその製造方法
FR3069757B1 (fr) * 2017-08-07 2021-07-23 Innovi Production Composition a base de sterols
BR112020002435B1 (pt) * 2017-08-07 2023-03-21 Elicit Plant Usos de pelo menos um tensoativo não iônico derivado a partir de polióis e um esterol
US20220312762A1 (en) * 2019-09-06 2022-10-06 The Texas A&M University System Use of encapsulated sterols to modify growth of crops, control, agricultural pests and as non-toxic pre-emergent herbicides
AU2022360261B2 (en) 2021-10-08 2025-05-22 Elicit Plant Phytosterol-based agricultural composition and their use
CN115969036B (zh) * 2023-01-10 2024-05-07 丰益油脂科技有限公司 植物甾醇颗粒物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3881005A (en) * 1973-08-13 1975-04-29 Lilly Co Eli Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof
JPS62186936A (ja) * 1986-02-13 1987-08-15 Asahi Denka Kogyo Kk ステリン乳化乃至可溶化組成物
US5405615A (en) 1991-09-17 1995-04-11 Micro Vesicular Systems, Inc. Sucrose distearate lipid vesicles
WO1999018977A1 (en) * 1997-10-16 1999-04-22 Medical Isotopes Inc. Readily absorbable phytosterol glycosides to treat hypercholesterolemia
IN185730B (de) * 1998-02-19 2001-04-14 Mcneil Ppc Inc

Also Published As

Publication number Publication date
BR0113621A (pt) 2003-07-22
AU2002213868A1 (en) 2002-03-13
EP1749520A1 (de) 2007-02-07
DE60124738T2 (de) 2007-09-13
DK1315482T3 (da) 2007-04-02
CY1106039T1 (el) 2011-04-06
CA2419249A1 (en) 2002-03-07
PT1315482E (pt) 2007-02-28
JP2004507492A (ja) 2004-03-11
WO2002017892A3 (en) 2002-05-16
HUP0300878A3 (en) 2008-03-28
ES2277952T3 (es) 2007-08-01
DE60124738D1 (de) 2007-01-04
EP1315482A2 (de) 2003-06-04
EP1315482B1 (de) 2006-11-22
HUP0300878A2 (hu) 2003-09-29
WO2002017892A2 (en) 2002-03-07
PL359704A1 (en) 2004-09-06
MXPA03001831A (es) 2003-06-04
GB0021498D0 (en) 2000-10-18
ATE345783T1 (de) 2006-12-15

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