BR0113621A - Esteróis encapsulados que podem ser dispersados em água - Google Patents

Esteróis encapsulados que podem ser dispersados em água

Info

Publication number
BR0113621A
BR0113621A BR0113621-6A BR0113621A BR0113621A BR 0113621 A BR0113621 A BR 0113621A BR 0113621 A BR0113621 A BR 0113621A BR 0113621 A BR0113621 A BR 0113621A
Authority
BR
Brazil
Prior art keywords
water
dispersed
sterols
encapsulated
micelles
Prior art date
Application number
BR0113621-6A
Other languages
English (en)
Inventor
Nicolas Auriou
Original Assignee
Novartis Nutrition Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Nutrition Ag filed Critical Novartis Nutrition Ag
Publication of BR0113621A publication Critical patent/BR0113621A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

"ESTERóIS ENCAPSULADOS QUE PODEM SER DISPERSADOS EM áGUA". A invenção refere-se a um método para a produção de um pó que pode ser dispersado em água que contém um ou mais esteróis. Este método envolve a criação de micelas que compreendem esterol e tensoativos em um meio aquoso, e o revestimento de tais micelas com uma mistura de amido e amido modificado em uma etapa de secagem. O pó seco pode ser adicionado de modo conveniente a formulações que possam ser comidas ou bebidas com base em água, permitindo dessa forma a administração do esterol de rebaixamento do colesterol em conjunto com uma dieta restrita de gorduras.
BR0113621-6A 2000-09-01 2001-08-30 Esteróis encapsulados que podem ser dispersados em água BR0113621A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0021498.1A GB0021498D0 (en) 2000-09-01 2000-09-01 New formulation
PCT/EP2001/010044 WO2002017892A2 (en) 2000-09-01 2001-08-30 Water-dispersible encapsulated sterols

Publications (1)

Publication Number Publication Date
BR0113621A true BR0113621A (pt) 2003-07-22

Family

ID=9898673

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113621-6A BR0113621A (pt) 2000-09-01 2001-08-30 Esteróis encapsulados que podem ser dispersados em água

Country Status (17)

Country Link
EP (2) EP1749520A1 (pt)
JP (1) JP2004507492A (pt)
AT (1) ATE345783T1 (pt)
AU (1) AU2002213868A1 (pt)
BR (1) BR0113621A (pt)
CA (1) CA2419249A1 (pt)
CY (1) CY1106039T1 (pt)
DE (1) DE60124738T2 (pt)
DK (1) DK1315482T3 (pt)
ES (1) ES2277952T3 (pt)
GB (1) GB0021498D0 (pt)
HU (1) HUP0300878A3 (pt)
MX (1) MXPA03001831A (pt)
PL (1) PL359704A1 (pt)
PT (1) PT1315482E (pt)
WO (1) WO2002017892A2 (pt)
ZA (1) ZA200301097B (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6773733B2 (en) 2001-03-26 2004-08-10 Loders Croklaan Usa Llc Structured particulate systems
US6673383B2 (en) * 2001-03-26 2004-01-06 Unilever Patent Holdings Bv Method for improving the performance of a food product
US20030003131A1 (en) * 2001-06-22 2003-01-02 Matthew Dyer Method for manufacture of free-flowing powder containing water-dispersible sterols
US20060147523A1 (en) 2002-10-16 2006-07-06 Alan Fergusson Composition for the regulation of the human immune system and the prevention and treatment of diseases thereof
DE10253111A1 (de) * 2002-11-13 2004-05-27 Basf Ag Pulverförmige Phytosterol-Formulierungen
JPWO2005018607A1 (ja) * 2003-08-20 2007-11-01 味の素株式会社 溶解性を改善した医薬品製剤
JP2007505642A (ja) * 2003-09-22 2007-03-15 ディグーサ ヘルス アンド ニュートリション アメリカズ インコーポレイテッド 香味料へのフィトステロールの配合
DE602005010972D1 (de) * 2004-01-30 2008-12-24 Unilever Nv Teilchenförmiges produkt, das phytosterole enthält, sowie nahrungsmittelzusammensetzungen, die dieses weissmittel enthalten
US20050233002A1 (en) * 2004-04-15 2005-10-20 Trubiano Paolo C Encapsulation of oxygen sensitive agents
ATE342338T1 (de) * 2004-06-04 2006-11-15 Procter & Gamble Verkapselte partikel
US20060034934A1 (en) * 2004-08-13 2006-02-16 Deguise Matthew L Agglomeration of sterol particles
WO2006025742A1 (en) * 2004-09-02 2006-03-09 Quest International Services B.V. Heat stable flavouring compositions
JP4915717B2 (ja) * 2004-09-09 2012-04-11 花王株式会社 肥満予防・改善剤
WO2006095798A1 (ja) * 2005-03-09 2006-09-14 Sunstar Inc. フィトステロールを含んだリポソームを含有する抗癌用経口組成物、該リポソームによる癌の予防又は治療
CA2673010A1 (en) * 2005-12-20 2007-06-28 Forbes Medi-Tech Inc. Compositions comprising one or more phytosterols and/or phytostanols, or derivatives thereof, and high hlb emulsifiers
US8309156B2 (en) 2005-12-20 2012-11-13 Pharmachem Laboratories, Inc. Compositions comprising one or more phytosterols and/or phytostanols, or derivatives thereof, and high HLB emulsifiers
JP4989956B2 (ja) * 2006-12-11 2012-08-01 松谷化学工業株式会社 粉末化植物ステロールエステル製剤、その製造方法及びこれを含む飲食品
KR20100097664A (ko) * 2007-12-05 2010-09-03 디에스엠 아이피 어셋츠 비.브이. 지용성 활성 성분의 분말 제형
WO2009071289A1 (en) * 2007-12-05 2009-06-11 Dsm Ip Assets B.V. Pulverous formulation of a fat-soluble active ingredient
EP2067410A1 (en) * 2007-12-07 2009-06-10 Cognis IP Management GmbH Water-dispersable sterol containing dispersion
US20110280937A1 (en) * 2009-02-13 2011-11-17 Nisshin Kasei Co., Ltd. Hard capsule
ES2374780A1 (es) * 2009-12-30 2012-02-22 José Javier Villa Cervera Procedimiento de fabricación de agua de beber, agua mineral, agua medicinal o similar, caracterizada porque incluye esteroles vegetales-fitoesteroles. la bebida contiene de 0.1 a 3 g litro de esteroles vegetales.
ES2524120T3 (es) 2010-12-28 2014-12-04 Unilever N.V. Método para la producción de una emulsión
US20120282368A1 (en) * 2011-05-03 2012-11-08 Brandeis University Amphiphilic sterol/fat-based particles
CN104822276A (zh) * 2012-11-07 2015-08-05 理研维他命股份有限公司 粉末状植物甾醇组合物及其制造方法
JP6092580B2 (ja) * 2012-11-07 2017-03-08 理研ビタミン株式会社 粉末状植物ステロール組成物およびその製造方法
JP6092579B2 (ja) * 2012-11-07 2017-03-08 理研ビタミン株式会社 粉末状植物ステロール組成物およびその製造方法
MA49832A (fr) 2017-08-07 2020-06-17 Elicit Plant Composition a base de polyol(s) et de sterol(s) pour usage dans le domaine agricole
FR3069757B1 (fr) * 2017-08-07 2021-07-23 Innovi Production Composition a base de sterols
US20220312762A1 (en) * 2019-09-06 2022-10-06 The Texas A&M University System Use of encapsulated sterols to modify growth of crops, control, agricultural pests and as non-toxic pre-emergent herbicides
KR20240070566A (ko) 2021-10-08 2024-05-21 엘리시트 플랜트 피토스테롤 기반 농업용 조성물 및 이의 용도
CN115969036B (zh) * 2023-01-10 2024-05-07 丰益油脂科技有限公司 植物甾醇颗粒物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3881005A (en) * 1973-08-13 1975-04-29 Lilly Co Eli Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof
JPS62186936A (ja) 1986-02-13 1987-08-15 Asahi Denka Kogyo Kk ステリン乳化乃至可溶化組成物
US5405615A (en) 1991-09-17 1995-04-11 Micro Vesicular Systems, Inc. Sucrose distearate lipid vesicles
WO1999018977A1 (en) 1997-10-16 1999-04-22 Medical Isotopes Inc. Readily absorbable phytosterol glycosides to treat hypercholesterolemia
IN185730B (pt) * 1998-02-19 2001-04-14 Mcneil Ppc Inc

Also Published As

Publication number Publication date
CA2419249A1 (en) 2002-03-07
DK1315482T3 (da) 2007-04-02
EP1315482A2 (en) 2003-06-04
PT1315482E (pt) 2007-02-28
CY1106039T1 (el) 2011-04-06
AU2002213868A1 (en) 2002-03-13
MXPA03001831A (es) 2003-06-04
EP1749520A1 (en) 2007-02-07
ZA200301097B (en) 2004-04-21
DE60124738D1 (de) 2007-01-04
EP1315482B1 (en) 2006-11-22
JP2004507492A (ja) 2004-03-11
WO2002017892A2 (en) 2002-03-07
ATE345783T1 (de) 2006-12-15
GB0021498D0 (en) 2000-10-18
DE60124738T2 (de) 2007-09-13
WO2002017892A3 (en) 2002-05-16
ES2277952T3 (es) 2007-08-01
PL359704A1 (en) 2004-09-06
HUP0300878A3 (en) 2008-03-28
HUP0300878A2 (hu) 2003-09-29

Similar Documents

Publication Publication Date Title
BR0113621A (pt) Esteróis encapsulados que podem ser dispersados em água
PL345163A1 (en) Sitostand formulation with emulsifier to reduce cholesterol absorption
AU7285987A (en) For facilitating the formation of lipid spherules dispersed in an aqueous phase and for improving their stability and their degree of encapsulation, and corresponding dispersions
BRPI9902623B1 (pt) composições em pó e em emulsão com vitaminas, comprimido efervescente, bebida e método de produção da composição em pó.
GB2337461B (en) Formulation
FI955527A0 (fi) Aerogeelien alikriittinen kuivausmenetelmä
AU2002347442A1 (en) Perfuming or flavouring microcapsules comprising a fireproofing agent
EP1184031A3 (fr) Crème cosmétique moussante pour le traitement des peaux grasses
WO2000003684A3 (en) Soy formulations and their use for promoting health
DK0832569T3 (da) Fremstilling af pulverformede, carotinoidpræparater, som kan dispergeres i koldt vand, og anvendelsen af de nye carotinoidpræparater
BR9904796A (pt) Gordura contendo fitosterol
WO2006062699A3 (en) Compositions and methods to deliver consumable water dispersible phytosterols
BR9704554B1 (pt) utilizaÇço de lipÍdios complexos como adiÇÕes de estabilizaÇço para composiÇÕes farmacÊuticas de misturas de enzimas de digestço, composiÇÕes farmacÊuticas soléveis em Água e kit para preparaÇço de soluÇÕes aquosas.
AR039118A1 (es) Barra alimenticia para mantener el estado de alerta
CA2340778A1 (en) Method for producing a cellulose suspension
DE69325112D1 (de) Fetter bestandteil
NO952575L (no) Flytende vanillinblanding, dens fremstilling og anvendelse
PE102599A1 (es) Procedimiento de fabricacion de leche en polvo, de una formula dietetica, de un producto culinario o de una base para cafe
NO20010491L (no) Vann-i-olje-mikroemulsjon som gir basisblandinger for tøymyknere kosmetiske attributter
FR2813187B1 (fr) Composition, notamment cosmetique, comprenant une sapogenine et une base xanthique
BR9905679A (pt) Composição em forma de um creme, utilização cosmética da composição, utilização da composição e processo de preparação de uma composição
EP0609465A4 (en) Custard cream.
PL353395A1 (en) Low fat spoonable or spreadable food products
NO169189C (no) Blanding paa basis av biopolymerer, fremgangsmaate for deres fremstilling og anvendelse av blandingen
BR0107701A (pt) Produtos alimentìcios e processos

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.