DE60124738D1 - In wasser dispergierbare verkapselte sterole - Google Patents

In wasser dispergierbare verkapselte sterole

Info

Publication number
DE60124738D1
DE60124738D1 DE60124738T DE60124738T DE60124738D1 DE 60124738 D1 DE60124738 D1 DE 60124738D1 DE 60124738 T DE60124738 T DE 60124738T DE 60124738 T DE60124738 T DE 60124738T DE 60124738 D1 DE60124738 D1 DE 60124738D1
Authority
DE
Germany
Prior art keywords
starch
capsulated
sterols
water dispersible
phytosterols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60124738T
Other languages
English (en)
Other versions
DE60124738T2 (de
Inventor
Nicolas Auriou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forbes Medi-Tech Inc
Original Assignee
Forbes Medi-Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forbes Medi-Tech Inc filed Critical Forbes Medi-Tech Inc
Publication of DE60124738D1 publication Critical patent/DE60124738D1/de
Application granted granted Critical
Publication of DE60124738T2 publication Critical patent/DE60124738T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
DE60124738T 2000-09-01 2001-08-30 In wasser dispergierbare verkapselte sterole Expired - Fee Related DE60124738T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0021498.1A GB0021498D0 (en) 2000-09-01 2000-09-01 New formulation
GB0021498 2000-09-01
PCT/EP2001/010044 WO2002017892A2 (en) 2000-09-01 2001-08-30 Water-dispersible encapsulated sterols

Publications (2)

Publication Number Publication Date
DE60124738D1 true DE60124738D1 (de) 2007-01-04
DE60124738T2 DE60124738T2 (de) 2007-09-13

Family

ID=9898673

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60124738T Expired - Fee Related DE60124738T2 (de) 2000-09-01 2001-08-30 In wasser dispergierbare verkapselte sterole

Country Status (17)

Country Link
EP (2) EP1315482B1 (de)
JP (1) JP2004507492A (de)
AT (1) ATE345783T1 (de)
AU (1) AU2002213868A1 (de)
BR (1) BR0113621A (de)
CA (1) CA2419249A1 (de)
CY (1) CY1106039T1 (de)
DE (1) DE60124738T2 (de)
DK (1) DK1315482T3 (de)
ES (1) ES2277952T3 (de)
GB (1) GB0021498D0 (de)
HU (1) HUP0300878A3 (de)
MX (1) MXPA03001831A (de)
PL (1) PL359704A1 (de)
PT (1) PT1315482E (de)
WO (1) WO2002017892A2 (de)
ZA (1) ZA200301097B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673383B2 (en) * 2001-03-26 2004-01-06 Unilever Patent Holdings Bv Method for improving the performance of a food product
US6773733B2 (en) 2001-03-26 2004-08-10 Loders Croklaan Usa Llc Structured particulate systems
US20030003131A1 (en) * 2001-06-22 2003-01-02 Matthew Dyer Method for manufacture of free-flowing powder containing water-dispersible sterols
US20060147523A1 (en) 2002-10-16 2006-07-06 Alan Fergusson Composition for the regulation of the human immune system and the prevention and treatment of diseases thereof
DE10253111A1 (de) * 2002-11-13 2004-05-27 Basf Ag Pulverförmige Phytosterol-Formulierungen
CA2536283A1 (en) * 2003-08-20 2005-03-03 Ajinomoto Co., Inc. Pharmaceutical preparations having an improved solubility
US20050064078A1 (en) * 2003-09-22 2005-03-24 Degussa Health & Nutrition Americas, Inc. Incorporation of phytosterols into flavorings
EP1708579B1 (de) * 2004-01-30 2008-11-12 Unilever N.V. Teilchenförmiges produkt, das phytosterole enthält, sowie nahrungsmittelzusammensetzungen, die dieses weissmittel enthalten
US20050233002A1 (en) * 2004-04-15 2005-10-20 Trubiano Paolo C Encapsulation of oxygen sensitive agents
EP1602713B1 (de) * 2004-06-04 2006-10-11 The Procter & Gamble Company Verkapselte Partikel
US20060034934A1 (en) * 2004-08-13 2006-02-16 Deguise Matthew L Agglomeration of sterol particles
EP1788896B1 (de) * 2004-09-02 2014-03-05 Givaudan Nederland Services B.V. Hitzestabile aromazusammensetzungen
JP4915717B2 (ja) * 2004-09-09 2012-04-11 花王株式会社 肥満予防・改善剤
EP1857112B1 (de) * 2005-03-09 2013-05-15 Sunstar Inc. Mittel gegen krebs mit phytosterol-haltigen liposomen
AU2006326830A1 (en) * 2005-12-20 2007-06-28 Forbes Medi-Tech Inc. Compositions comprising one or more phytosterols and/or phytostanols, or derivatives thereof, and high HLB emulsifiers
US8309156B2 (en) 2005-12-20 2012-11-13 Pharmachem Laboratories, Inc. Compositions comprising one or more phytosterols and/or phytostanols, or derivatives thereof, and high HLB emulsifiers
JP4989956B2 (ja) * 2006-12-11 2012-08-01 松谷化学工業株式会社 粉末化植物ステロールエステル製剤、その製造方法及びこれを含む飲食品
EP2217094A1 (de) * 2007-12-05 2010-08-18 DSM IP Assets B.V. Pulverförmige formulierung eines fettlöslichen aktiven inhaltsstoffes
KR20100097665A (ko) * 2007-12-05 2010-09-03 디에스엠 아이피 어셋츠 비.브이. 지용성 활성 성분의 분말 제형
EP2067410A1 (de) * 2007-12-07 2009-06-10 Cognis IP Management GmbH Wasser dispergierbares Sterol enthaltende Dispersion
CA2751703A1 (en) * 2009-02-13 2010-08-19 Nisshin Kasei Co., Ltd. Hard capsule
ES2374780A1 (es) * 2009-12-30 2012-02-22 José Javier Villa Cervera Procedimiento de fabricación de agua de beber, agua mineral, agua medicinal o similar, caracterizada porque incluye esteroles vegetales-fitoesteroles. la bebida contiene de 0.1 a 3 g litro de esteroles vegetales.
US9352289B2 (en) 2010-12-28 2016-05-31 Conopco, Inc. Method for production of an emulsion
US20120282368A1 (en) * 2011-05-03 2012-11-08 Brandeis University Amphiphilic sterol/fat-based particles
JP6092580B2 (ja) * 2012-11-07 2017-03-08 理研ビタミン株式会社 粉末状植物ステロール組成物およびその製造方法
JP6092579B2 (ja) * 2012-11-07 2017-03-08 理研ビタミン株式会社 粉末状植物ステロール組成物およびその製造方法
WO2014073542A1 (ja) * 2012-11-07 2014-05-15 理研ビタミン株式会社 粉末状植物ステロール組成物およびその製造方法
FR3069757B1 (fr) * 2017-08-07 2021-07-23 Innovi Production Composition a base de sterols
MA49832A (fr) * 2017-08-07 2020-06-17 Elicit Plant Composition a base de polyol(s) et de sterol(s) pour usage dans le domaine agricole
EP4025703A4 (de) * 2019-09-06 2023-09-06 The Texas A&M University System Verwendung von verkapselten sterolen zur modifizierung des wachstums von nutzpflanzen, zur bekämpfung von landwirtschaftlichen schädlingen und als nicht-toxische herbizide im vorauflauf
CN115969036B (zh) * 2023-01-10 2024-05-07 丰益油脂科技有限公司 植物甾醇颗粒物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3881005A (en) 1973-08-13 1975-04-29 Lilly Co Eli Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof
JPS62186936A (ja) * 1986-02-13 1987-08-15 Asahi Denka Kogyo Kk ステリン乳化乃至可溶化組成物
US5405615A (en) 1991-09-17 1995-04-11 Micro Vesicular Systems, Inc. Sucrose distearate lipid vesicles
WO1999018977A1 (en) 1997-10-16 1999-04-22 Medical Isotopes Inc. Readily absorbable phytosterol glycosides to treat hypercholesterolemia
IN185730B (de) * 1998-02-19 2001-04-14 Mcneil Ppc Inc

Also Published As

Publication number Publication date
PT1315482E (pt) 2007-02-28
HUP0300878A2 (hu) 2003-09-29
ZA200301097B (en) 2004-04-21
DK1315482T3 (da) 2007-04-02
BR0113621A (pt) 2003-07-22
GB0021498D0 (en) 2000-10-18
EP1315482A2 (de) 2003-06-04
ATE345783T1 (de) 2006-12-15
WO2002017892A3 (en) 2002-05-16
MXPA03001831A (es) 2003-06-04
ES2277952T3 (es) 2007-08-01
CA2419249A1 (en) 2002-03-07
EP1315482B1 (de) 2006-11-22
PL359704A1 (en) 2004-09-06
HUP0300878A3 (en) 2008-03-28
WO2002017892A2 (en) 2002-03-07
CY1106039T1 (el) 2011-04-06
AU2002213868A1 (en) 2002-03-13
DE60124738T2 (de) 2007-09-13
EP1749520A1 (de) 2007-02-07
JP2004507492A (ja) 2004-03-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee