ZA200105344B - Cell adhesion-inhibiting antiinflamatory and immune-suppressive compounds. - Google Patents

Cell adhesion-inhibiting antiinflamatory and immune-suppressive compounds. Download PDF

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Publication number
ZA200105344B
ZA200105344B ZA200105344A ZA200105344A ZA200105344B ZA 200105344 B ZA200105344 B ZA 200105344B ZA 200105344 A ZA200105344 A ZA 200105344A ZA 200105344 A ZA200105344 A ZA 200105344A ZA 200105344 B ZA200105344 B ZA 200105344B
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South Africa
Prior art keywords
phenyl
sulfide
carbonyl
ethenyl
nitro
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ZA200105344A
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English (en)
Inventor
James Link
Zhonghua Pei
Martin Winn
Steven A Boyd
John K Lynch
Jennifer C Freeman
Michael A Staeger
Gang Liu
Tom Von Geldern
Zhili Xin
Hwan-Soo Jae
Gui-Dong Zhu
Indrani W Gunawardana
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Abbott Lab
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Publication of ZA200105344B publication Critical patent/ZA200105344B/en

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
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    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/00—Drugs for skeletal disorders
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D209/04—Indoles; Hydrogenated indoles
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    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
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    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
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ZA200105344A 1998-12-29 2001-06-28 Cell adhesion-inhibiting antiinflamatory and immune-suppressive compounds. ZA200105344B (en)

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US09/222,491 US6110922A (en) 1998-12-29 1998-12-29 Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds

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KR100640984B1 (ko) 2006-11-03
CN1192018C (zh) 2005-03-09
EP1140814B1 (en) 2005-05-25
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DE69925508T2 (de) 2006-05-04
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IL143968A0 (en) 2002-04-21
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NO20013241D0 (no) 2001-06-28
GEP20043383B (en) 2004-07-12
EP1140814A2 (en) 2001-10-10
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CA2356320A1 (en) 2000-07-06
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UA72909C2 (en) 2005-05-16
HUP0200222A3 (en) 2003-01-28
CN1955164A (zh) 2007-05-02
CZ20012412A3 (cs) 2002-04-17
EE200100355A (et) 2002-10-15
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