ATE296283T1 - Zelladhäsion- und entzündungshemmende immunosuppressive verbindungen - Google Patents

Zelladhäsion- und entzündungshemmende immunosuppressive verbindungen

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Publication number
ATE296283T1
ATE296283T1 AT99966709T AT99966709T ATE296283T1 AT E296283 T1 ATE296283 T1 AT E296283T1 AT 99966709 T AT99966709 T AT 99966709T AT 99966709 T AT99966709 T AT 99966709T AT E296283 T1 ATE296283 T1 AT E296283T1
Authority
AT
Austria
Prior art keywords
cell adhesion
immunosuppressive compounds
compounds
inflammatory immunosuppressive
inflammatory
Prior art date
Application number
AT99966709T
Other languages
English (en)
Inventor
James Link
Gang Liu
Zhonghua Pei
Geldern Tom Von
Martin Winn
Zhili Xin
Steven A Boyd
Hwan-Soo Jae
John K Lynch
Gui-Dong Zhu
Jennifer C Freeman
Indrani W Gunawardana
Michael A Staeger
Original Assignee
Abbott Lab
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Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE296283T1 publication Critical patent/ATE296283T1/de

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
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AT99966709T 1998-12-29 1999-12-29 Zelladhäsion- und entzündungshemmende immunosuppressive verbindungen ATE296283T1 (de)

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US09/222,491 US6110922A (en) 1998-12-29 1998-12-29 Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
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CZ296726B6 (cs) 2006-05-17
JP4057244B2 (ja) 2008-03-05
EP1140814B1 (de) 2005-05-25
HK1041476B (zh) 2006-01-06
DE69925508D1 (de) 2005-06-30
CN1192018C (zh) 2005-03-09
PL350786A1 (en) 2003-02-10
AU2220300A (en) 2000-07-31
US6110922A (en) 2000-08-29
EP1140814A2 (de) 2001-10-10
IL143968A0 (en) 2002-04-21
NZ512687A (en) 2003-12-19
HUP0200222A2 (en) 2002-06-29
NO20013241D0 (no) 2001-06-28
KR100640984B1 (ko) 2006-11-03
KR20010094742A (ko) 2001-11-01
NO20013241L (no) 2001-08-28
HRP20010512B1 (en) 2006-02-28
CA2356320A1 (en) 2000-07-06
EE200100355A (et) 2002-10-15
EA200100732A1 (ru) 2002-02-28
SK9402001A3 (en) 2002-01-07
BG65177B1 (bg) 2007-05-31
USRE39197E1 (en) 2006-07-18
PL195605B1 (pl) 2007-10-31
WO2000039081A2 (en) 2000-07-06
WO2000039081A3 (en) 2001-05-25
GEP20043383B (en) 2004-07-12
HUP0200222A3 (en) 2003-01-28
CN1350520A (zh) 2002-05-22
EA005207B1 (ru) 2004-12-30
HK1041476A1 (en) 2002-07-12
HRP20010512A2 (en) 2002-08-31
ZA200105344B (en) 2003-09-16
JP2002533434A (ja) 2002-10-08
CN1955164A (zh) 2007-05-02
BR9916638A (pt) 2004-08-10
UA72909C2 (en) 2005-05-16
BG105732A (en) 2002-02-28
CZ20012412A3 (cs) 2002-04-17
CA2356320C (en) 2006-07-18
MXPA01006636A (es) 2002-07-22
IS5985A (is) 2001-06-28
AU771126B2 (en) 2004-03-11
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