WO2009033469A1 - Herzklappenstent - Google Patents
Herzklappenstent Download PDFInfo
- Publication number
- WO2009033469A1 WO2009033469A1 PCT/DE2008/001515 DE2008001515W WO2009033469A1 WO 2009033469 A1 WO2009033469 A1 WO 2009033469A1 DE 2008001515 W DE2008001515 W DE 2008001515W WO 2009033469 A1 WO2009033469 A1 WO 2009033469A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stent
- heart valve
- valve
- heart
- anchoring
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2445—Annuloplasty rings in direct contact with the valve annulus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
- A61F2/2457—Chordae tendineae prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2478—Passive devices for improving the function of the heart muscle, i.e. devices for reshaping the external surface of the heart, e.g. bags, strips or bands
- A61F2/2487—Devices within the heart chamber, e.g. splints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00243—Type of minimally invasive operation cardiac
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B2017/0496—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials for tensioning sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2436—Deployment by retracting a sheath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0008—Rounded shapes, e.g. with rounded corners elliptical or oval
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0013—Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/005—Rosette-shaped, e.g. star-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0067—Three-dimensional shapes conical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0073—Quadric-shaped
- A61F2230/0078—Quadric-shaped hyperboloidal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0004—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
- A61F2250/001—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting a diameter
Definitions
- the invention relates to a heart valve stent having a section set up for receiving a heart valve implant and having a plurality of anchoring elements arranged proximally.
- Such heart valve stents are known in a variety of configurations for the replacement of malformed or pathologically altered heart valves.
- the surgical implantation of heart valve prostheses is performed regularly on the cardioplegic heart.
- the old, functionally impaired heart valve is cut out and the implanted heart valve prosthesis sewn.
- the tendon threads ⁇ chordae tendineae) of the mitral valve should be retained as far as possible in their structure in order to obtain or achieve the ventricular geometry and thus the best possible function of the left ventricle as far as possible. It is of great importance that the anterior (anterior) mitral valve leaflet is not simply pushed in the free space towards the left ventricle, but is attached to the mitral valve annulus to allow for forward urging of the anterior mitral valve leaflet into the outflow tract. the left ventricle (Sam's phenomenon: systolic anterior movement) is prevented. This is extremely important because otherwise it can quickly lead to left heart decompensation (massive misconduct of the left ventricle).
- the old mitral valve is attached to the old annulus, so that there is an unimpeded blood flow through the valve and through the two adjoining chambers of the heart.
- the prosthetic heart valve is surgically implanted in this annulus by suturing.
- DE 195 46 692 C2 or EP 1 469 797 B1 discloses a self-expandable cardiac valve prosthesis for implantation in the human body via a catheter system having a heart valve and a collapsible and expandable stent connected to the heart valve.
- a self-expanding heart valve prosthesis can be guided by a catheter system through a groin artery to the implantation at the heart. After reaching the implantation site, such a stent, which is composed in its longitudinal direction of a plurality of self-expanding segments which can be bent relative to one another, can then be unfolded successively. After deployment, the heart valve prosthesis can be anchored with the aid of anchoring hooks, at least in the area close to the heart, in the respective blood vessel.
- a better positioning and angular alignment can be achieved by the stent known from EP 1 469 797 B1, in which so-called support brackets are formed, which can be introduced into the aortic pockets and thus produce a defined distance to the aortic valve.
- the object is achieved by the heart valve stent having the features of claim 1.
- the subclaims reflect advantageous embodiments of the invention.
- the basic idea of the invention is to create a heart valve stent which creates the anatomical prerequisites for a natural function, similar to a healthy heart.
- a minimally invasive operation which ensures exact positioning and secure fixation of the valve stent, is made possible with the heart valve stent according to the invention in the self-expanding foldable embodiment.
- the heart valve stent according to the invention is designed as a mitral valve stent, a tension between mitral valve and ventricle similar to the natural tendon thread tension (the chordae tendineae) is generated and at the same time ensured that the valve components of the old mitral valve (in particular the anterior mitral valve leaflet) no longer the flow of the Disturb blood.
- valve stent according to the invention is catheter-assisted introduced through one of the heart chambers or the adjacent large vessels of the heart, then can unfold in one of the heart chambers, wherein its anchoring elements are fixed in the tissue. Finally, the stent is fixed to the subvalvular heart chamber wall opposite the stent with formation of a tension between the ventricular wall and the proximal, supravalvularly anchored anchoring elements with anchoring threads (also referred to below as neo-chordae).
- the fixation of the anchoring threads in the distal heart chamber wall thus constitutes an abutment to the proximal anchoring elements, which abutment can be achieved, for example, by a knee joint. or formed by another element acting as an abutment.
- This abutment can preferably also be designed as Kladeninnstellelement.
- Advantages of the heart valve stent according to the invention are thus accurate and simple fixation of the heart valve stent with minimally invasive surgery and improved contractility of the heart over conventional valve stents.
- the anchoring threads aligned axially with respect to the longitudinal axis of the valve stent according to the invention are fastened with their one end to the annulus of Herzklappenimp- lantat so that when forming the voltage between the stent and Herzhuntwandung a direct effect on the positioning and angulare orientation of the flap can be achieved.
- the anchoring threads may also be connected to the stent at the distal flap stem.
- the connection between the anchoring thread and the stent must be made such that a tension running in the axial direction substantially in relation to the longitudinal axis of the stent can be formed between the proximal anchoring elements and the distal abutment.
- the anchoring threads (neo-chordae) elements for length adjustment of the anchoring thread with the length of the anchoring threads for setting a certain voltage between heart valve stent and heart wall can be adjusted.
- a Dermathomae be provided for each thread or, for example, a Kaydeninnstellelement for all threads together.
- the filament length adjusting element is preferably made small and can be set up, for example, such that the element shortens the thread to the desired length by winding up an excess thread length.
- the design of elastic anchoring threads in the axial direction which can react to contraction movements of the heart, without an excessively long thread length, which could adversely affect cardiac function.
- the length of the thread should be chosen so that the elasticity is not completely at the expense of the tension between the anchoring elements and the heart wall. If the abutment is designed as Kladeninnstellelement, there is a particularly advantageous embodiment, since this also a readjustment of the voltage between anchoring elements and abutment, so a re-tensioning the anchoring is possible without the heart would have to be opened.
- the structure of the mitral valve stent in the plane of the mitral valve annulus is substantially oval or U-shaped, so that no pressure is exerted on the left ventricular outflow tract (LVOT) and / or aortic annulus and therewith impaired cardiac function Missing (Ma L, Tozzi P, Huber CH, Taub S 5 Gerelle G, by Segesser LK) Double crowned valved stents for off-pump mitral valve replacement. Eur J Cardiothorac Surg. 2005 Aug; 28 (2): 194-8 ; discussion 198-9).
- This valve stent receives a highly conforming shape, perfectly adapted to the natural mitral valve apparatus, so that this conically tapering (cranial-caudal axis) not quite circular (oval-like in the transversal axis) valve stent strongly adapts to the natural shape
- the mitral valve can create and lean against.
- the valve stent In the anterior mitral annulus annulus, the valve stent is shallow and results in almost no pressure and no constriction on the LVOT. It is oval in the area of the posterior mitral annulus and reproduces the shape of the posterior annulus.
- This valve stent forms a thin, cranial-caudal structure, which conforms completely to the mitral valve in shape and thus looks like a negative impression in the region of the natural mitral valve annulus.
- the valve stent touches the old mitral valve and its annulus, it leaves them almost completely unchanged in their anatomy.
- Fig. 1 shows a preferred embodiment of the valve stent according to the invention in a schematic side view
- FIG. 2 shows the exemplary embodiment shown in FIG. 1 in plan view from above;
- Fig. 3 is a plan view of a plurality of particularly preferred trained flap stents according to the invention.
- FIG. 5 shows a schematic view to illustrate the minimally invasive transplantation of a mitral valve stent according to the invention in a first phase when introducing the mitral valve stent according to the invention to the transplantation site;
- Fig. 6 is a schematic view illustrating the minimally invasive transplantation of a mitral valve stent according to the invention in a second phase after positioning of the mitral valve;
- FIG. 7 shows a schematic view to illustrate the minimally invasive transplantation of a mitral valve stent according to the invention after completion of the fixation of the anchoring threads outside the apex of the left ventricular heart wall;
- FIG. 8 shows a schematic view of an alternative intracardiac fixation of the anchoring threads in the region of the papillary muscles
- FIG. 9 is a schematic view of a fixed in the aortic annulus heart valve stent according to the invention.
- 10 is a schematic view of a fixed in the pulmonary position heart valve stent according to the invention.
- Figure 11 is a schematic view of a fixed in the tricuspid position heart valve stent according to the invention.
- valve stent 12 shows a particularly preferred exemplary embodiment of the valve stent according to the invention in a schematic side view without heart valve and anchoring thread
- FIG. 13 shows a schematic, dorsal, intracardial view of a heart valve stent fixed in the mitral position according to the invention.
- FIG. 1 to 11 show the inventive stent for implantation and attachment of heart valve prostheses in various views to illustrate the structure of the stent and the spatial relationships of the individual stent sections to each other in unfolded ( Figures 1-4 and 6-11) and in the folded state (Figure 5).
- FIG. 1 shows a foldable mitral valve stent 10 according to the invention in a perspective lateral view.
- the stent 10 essentially has three sections: Proximal
- anchoring elements 20 are arranged, which implanted the valve stent 10 in the
- Anchor state supravalvular or atrial
- the conical and oval-shaped cross-sectionally shaped stent body 30 Disposed distally adjacent to one another is the conical and oval-shaped cross-sectionally shaped stent body 30, which is preferably flattened to the LVOT (compare FIG. 2).
- the stent body 30 forms a basket or trapezoidal figure that conforms to the mitral valve annulus and extends toward the left ventricle.
- This stent 10 is held in the atrium by its tapered shape and by the atrial anchorage.
- a two- or dreizipflige flap 50 may be integrated.
- Anchoring threads 40 which are arranged distally from this stent body 30 for anchoring the entire stent 10, are located distally to the stent body 30 (towards the left ventricle). These anchoring threads 40 provide anchoring in the opposite
- Ventricular wall or e.g. in the area of the papillary muscle (proximal, medial or distal
- These anchoring threads 40 can be positioned by means of an adjustable thread length adjustment element 70 and adjusted to the optimum length, so that the heart valve stent 10 can then be fixed and anchored.
- Fig. 2 shows the stent 10 in a plan view. It can be seen that the stent 10 forms a neo-annulus or stent body 30, into which the heart valve prosthesis 50 can be inserted and to which it can be attached. Furthermore, it can be seen that the stent 10 according to the invention may be designed asymmetrically with respect to the plurality of supravalvular (atrial) stent bars 20. This can be seen from the fact that the stent body 30 is oval-shaped in this figure and flattened on one side, that is substantially U-shaped, so that it can be used at this flattened point in the direction of LVOTs.
- FIG. 4 shows the stent 10 according to the invention in a bottom view. It can be seen that the diameter of the atrial portion to the ventricular portion of the stent body
- Both the fasteners 20 and the stent body 30 may be provided with fabric (e.g., plastic,
- FIGS. 5 to 7 and 8 describe the retrograde transapical implantation of a valve stent.
- the retrograde transaortic as well as the antegrade transatrial access route may alternatively be performed.
- the placement of the valve stent with a folded valve stent over the old mitral valve annulus is shown in FIG.
- the deployment of the atrial anchoring elements 20 e.g., preferably self-expanding
- Positioning in the left atrium should be done so that the flattened side of the stent body 30 is in the direction of being LVOT (aortic valve).
- the stent is then expanded further.
- Fig. 6 shows the expanded valve stent 10 in the left atrio-ventricular inflow tract.
- Anchoring threads 40 are adjusted on, in or outside the heart wall and later - as shown in Fig. 7 - fixed by means of the preferably designed as Kladeninnstellelement abutment 80.
- the length of the anchoring threads 40 i.a. also a visualization of the mitral valve apparatus (eg echo, CT or NMR) so that the annulus can be pulled optimally in the direction of the ventricle wall by means of the new stent 10, there is no paravalvular leak, the stent 10 is well fixed and the mitral valve annulus and apparatus advantageously supports the left ventricular function.
- the mitral valve apparatus eg echo, CT or NMR
- the anchoring threads 40 can also be attached to the papillary muscles (see FIG. 8), so that these threads 40 represent neo-chordae and can take over the function of the inactive chordae tendineae.
- the anchoring threads 40 are fastened to the heart wall in each case by means of an abutment 80, which can be designed as a knot or as an independent element.
- the ventricular anchoring threads 40 are attached not only to the stent body 30 but also to the integrated flap itself. These caudal anchoring cords 40 may also be fixed at any other point in the ventricle.
- FIG. 7 shows the completed positioning and fixation of the stent 10.
- the adjustable thread length adjusting element 70 serves to optimally adjust the length and position of the flap stent 10 and thus of the valve prosthesis 50.
- Different threads 40 may have different lengths and attachment positions in the ventricle.
- FIG. 9 to 11 show further examples of the use of the heart valve stent 10 according to the invention, wherein the stent 10 is adapted to the respective anatomy (for the aortic and pulmonary valve position a more circular shape (see Fig. 3) and for Tricuspid position is a rather oval shape).
- FIG. 12 shows a particularly preferred embodiment of the valve stent according to the invention in a schematic side view, which is shown for clarity without heart valve and anchoring threads.
- FIG. 13 shows a schematic, dorsal, intracardial view of a heart valve stent fixed in the mitral position according to the invention. Note the good nestling of the valve stent to the left atrial environment. Distances between the left atrial wall / mitral annulus and the valve stent are thus avoided. Heart valve and anchoring thread to the ventricular tip have been omitted for ease of illustration.
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Prostheses (AREA)
Abstract
Herzklappenstent (10) mit einem zur Aufnahme eines Herzklappenimplantats (30) eingerichteten Abschnitt und mit einer Mehrzahl von proximal angeordneten Verankerungselementen (20), gekennzeichnet durch eine Mehrzahl von Verankerungsfäden (40), die mit ihrem einen Ende am Stent (10) befestigt sind, und einem die Verankerungsfäden (40) mit ihrem anderen Ende an der distalen Herzkammerwandung unter Ausbildung einer Spannung zwischen der Herzkammerwandung und den proximal verankerten Verankerungselementen (20) befestigenden Widerlager (80).
Description
Herzklappenstent
Die Erfindung betrifft einen Herzklappenstent mit einem zur Aufnahme eines Herzklappenimplantats eingerichteten Abschnitt und mit einer Mehrzahl von proximal angeordneten Verankerungselementen.
Derartige Herzklappenstents sind in einer Vielzahl von Ausbildungen zum Ersatz fehlgebilde- ter oder krankhaft veränderter Herzklappen bekannt. Dabei wird die chirurgische Implantation von Herzklappenprothesen regelmäßig am kardioplegischen Herzen durchgeführt. Die alte, in ihrer Funktion beeinträchtigte Herzklappe wird herausgeschnitten und die zu implantierende Herzklappenprothese eingenäht.
Bei Vorliegen von Erkrankungen der Mitralklappe hingegen wird versucht, die alte Klappe trotz aufgetretener Fehlfunktion weitestgehend zu erhalten, damit der gesamte dynamische Mitralklappenapparat nicht zerstört wird. Das liegt daran, dass z.B. die an der Mitralklappe ansetzenden Sehnenfäden (chordae tendineae) für die Ventrikelfunktion sehr wichtig sind und daher möglichst nicht von der alten Mitralklappe losgelöst werden sollten.
Ideal ist es daher, die Mitralklappe (wenn sie nicht rekonstruiert werden kann) weitestgehend zur Seite zu drängen, um der Klappenprothese Platz zu machen. Der Platz spielt hier eine nicht so gravierende Rolle wie in dem Aortenannulus, bei dem eine Einengung viel leichter zu Stande kommt (z.B. beim Verdrängen der alten Aortenklappe bei rein perkutaner Implantati- on).
Die Sehnenfäden {chordae tendineae) der Mitralklappe sollten dabei nach Möglichkeit in ihrer Struktur erhalten bleiben, um die Ventrikelgeometrie und damit eine bestmögliche Funktion der linken Kammer weitestgehend zu erhalten bzw. zu erreichen. Hierbei ist es von enor- mer Bedeutung, dass das vordere (anteriore) Mitralklappensegel nicht einfach in den freien Raum Richtung linken Ventrikel gedrückt wird, sondern an den Mitralklappenannulus angeheftet wird, damit ein Vorwärts-Drängen des vorderen Mitralklappensegels in den Ausfluss-
trakt des linken Ventrikels (Sam-Phänomen: Systolic Anterior Movement) verhindert wird. Dieses ist außerordentlich wichtig, da es sonst schnell zu einer Linksherz-Dekompensation (massives Fehlverhalten des linken Ventrikels) kommen kann.
Chirurgisch wird also die alte Mitralklappe an den alten Annulus angeheftet, so dass ein ungehinderter Blutfluss durch die Klappe und durch die beiden anliegenden Herzkammern gegeben ist. Nach dem Zurückdrängen (dem Anheften der Klappe an den Annulus) wird die Herzklappenprothese chirurgisch in diesen Annulus durch Einnähen implantiert.
Diese aufwendige Methode geschieht obligatorisch unter zur Hilfenahme der Herz-Lungen- Maschine und kommt für Hochrisikopatienten regelmäßig nicht in Frage, sodass nach mini- mal-invasiven oder perkutanen Methoden zur Implantation einer Herzklappe gesucht wird.
So ist aus der DE 195 46 692 C2 oder in EP 1 469 797 Bl eine selbstexpandierbare Herzklap- penprothese zur Implantation im menschlichen Körper über ein Kathetersystem mit einer Herzklappe und mit einem mit der Herzklappe verbundenen zusammenfaltbaren und expandierbaren Stent bekannt. Eine solche selbstexpandierbare Herzklappenprothese kann mit Hilfe eines Kathetersystems durch eine Leistenarterie bis hin zum Implantationsort am Herzen geführt werden. Nach Erreichen des Implantationsortes kann dann ein solcher Stent, der in sei- ner Längsrichtung aus mehreren relativ zueinander abwinkelbaren selbstexpandierenden Segmenten zusammengesetzt ist, sukzessiv entfaltet werden. Nach der Entfaltung kann die Herzklappenprothese mit Unterstützung von Verankerungshaken zumindest im herznahen Bereich im jeweiligen Blutgefäss verankert werden.
Eine weitere Vorrichtung zur Befestigung und Verankerung von Herklappenprothesen ist in der DE 100 10 074 Al beschrieben, die im Wesentlichen aus drahtförmigen miteinander verbundenen Elementen gebildet wird. Verschieden ausgebildete Bügel werden hierbei eingesetzt, um eine sichere Befestigung und Abstützung einer Herzklappe zu erreichen.
Bei diesen bekannten Lösungen besteht jedoch die Gefahr einer Fehlimplantation von Herklappen durch fehlerhafte Positionierung und der fehlerhafte angulare Ausrichtung der zu implantierenden Herzklappenprothese.
Eine bessere Positionierung und angulare Ausrichtung kann durch den aus der EP 1 469 797 Bl bekannten Stent erreicht werden, bei dem sogenannte Stützbügel ausgebildet sind, die in die Aortentaschen einführbar sind und so eine definierte Entfernung zur Aortenklappe herstellen. Darüber hinaus besteht auch die Möglichkeit eine fehlgeschlagene Implantation einer Herzklappenprothese abzubrechen und den Klappenstent wieder in das Kathetersystem bzw. die sogenannte die Kartusche hineinzuziehen. Hierbei wird dann der gesamte Stent zusammengefaltet und in die Kartusche zurückgeführt. Dabei ist es möglich den Stent erneut heraus gleiten zu lassen, sodass eine gute Positionierung für den Klappenstent nach mehreren Positionierungsversuchen erreicht werden kann („sliding technique").
Ein weitaus größeres Problem für die optimale Platzierung der neuen Herzklappe im Stent (bzw. Klappenstent) besteht jedoch darin, dass die alte native Klappe in den meisten Fällen der zuvor beschriebenen Implantationstechnik nicht entfernt werden soll.
Dies führt jedoch dazu, dass die neue Klappe, die in eine alte, deformierte Klappe hineinge- drückt (teilweise hineingequetscht) wird, in ihrer ursprünglichen Stentform abgewandelt wird. Dies liegt daran, dass der Implantationsort für den Klappenstent durch die Anatomie, den Zustand und die Beschaffenheit der alten nativen Klappe bestimmt wird (z.B. bei Klappensklerose oder -Verkalkung der nativen Klappe).
Daher bestimmt der alte Klappenannulus mit den dazugehörigen veränderten Klappen/Taschen inwieweit und wohin sich die neue Klappe entfalten und damit in ihrer Form entwickeln kann. Somit ist also nicht nur die Verankerung/Positionierung wichtig, um eine optimale Klappenfunktion, sowie Vorhof- und Ventrikelfunktion zu erhalten, sondern auch das Einpassen des Klappenstents in den Neo-Annulus (alter Klappenannulus bildet diesen mit alter Klappe aus) und damit das Zurückdrängen der alten Klappe.
Ausgehend von den bei den bekannten Herzklappenstents auftretenden Problemen, ist es daher Aufgabe der Erfindung einen Herzklappenstent, insbesondere einen Mitralklappenstent für die minimal-invasive Transplantation, zu schaffen, der eine möglichst natürliche Funktionsausübung des Herzens ermöglicht.
Erfindungsgemäß wird die Aufgabe durch den Herzklappenstent mit den Merkmalen von Anspruch 1 gelöst. Die Unteransprüche geben vorteilhafte Ausgestaltungen der Erfindung wieder.
Grundgedanke der Erfindung ist es, einen Herzklappenstent zu schaffen, der die anatomischen Voraussetzungen für eine natürliche Funktionsausübung, ähnlich einem gesunden Herz, schafft. Dabei ist mit dem erfindungsgemäßen Herzklappenstent in der selbstexpandierend faltbaren Ausgestaltung eine minimal-invasive Operation ermöglicht, die eine exakte Positionierung und sichere Fixierung des Klappenstents gewährleistet. Dabei wird, insbesondere bei Ausbildung des erfindungsgemäßen Herzklappenstents als Mitralklappenstent, eine Spannung zwischen Mitralklappe und Ventrikel ähnlich der natürlichen Sehnenfadenspannung (der chordae tendineae) erzeugt und gleichzeitig dafür gesorgt, dass die Klappenanteile der alten Mitralklappe (insbesondere das anteriore Mitralklappensegel) nicht mehr den Durchfluss des Blutes stören.
Es ist also vorgesehen, dass der Klappenstent nach der Erfindung kathetergestützt durch eines der Herzkammern oder der angrenzenden, großen Gefäße des Herzens eingeführt wird, sich dann in einer der Herzkammern entfalten kann, wobei seine Verankerungselemente im Gewebe fixiert werden. Abschließend wird der Stent an der dem Stent gegenüberliegenden, subval- vulären Herzkammerwandung unter Ausbildung einer Spannung zwischen der Herzkammerwandung und den proximal, supravalvulär verankerten Verankerungselementen mit Verankerungsfäden (im Folgenden auch neo-chordae genannt) fixiert.
Die Fixierung der Verankerungsfäden in der distalen Herzkammerwandung stellt also zu den proximalen Verankerungselementen ein Widerlager dar, das beispielsweise durch einen Kno-
ten oder durch ein anderes als Widerlager wirkendes Element gebildet wird. Dieses Widerlager kann bevorzugt auch als Fädenlängenstellelement ausgebildet sein.
Vorteile des erfindungsgemäßen Herzklappenstents sind also genaue und einfache Fixierung des Herzklappenstents bei minimal-invasiver Operation und verbesserte Kontraktilität des Herzens gegenüber herkömmlichen Klappenstents.
Bevorzugt sind die im Verhältnis zur Längsachse des erfindungsgemäßen Klappenstents axial ausgerichteten Verankerungsfäden mit ihrem einen Ende am Annulus des Herzklappenimp- lantats befestigt, sodass bei Ausbildung der Spannung zwischen Stent und Herzkammerwandung eine direkte Wirkung auf die Positionierung und angulare Ausrichtung der Klappe erreicht werden kann. Die Verankerungsfäden können jedoch auch am distalen Klappensten- tumfang mit dem Stent verbunden sein. Die Verbindung zwischen Verankerungsfaden und Stent muss jedoch so vorgenommen sein, dass eine im Wesentlichen im Verhältnis zur Längsachse des Stents in axialer Richtung verlaufende Spannung zwischen proximalen Verankerungselementen und distalem Widerlager ausgebildet werden kann.
Nach einer weiteren bevorzugten Ausgestaltung der Erfindung weisen die Verankerungsfäden (neo-chordae) Elemente zur Längenverstellung der Verankerungsfaden auf, mit den die Län- ge der Verankerungsfäden zum Einstellen einer bestimmten Spannung zwischen Herzklap- penstent und Herzwandung eingestellt werden kann. Dabei kann beispielsweise ein Fädenlängenstellelement für je einen Faden oder beispielweise ein Fädenlängenstellelement für alle Fäden gemeinsam vorgesehen sein. Das Fädenlängenstellelement ist bevorzugt klein ausgebildet und kann beispielsweise derart eingerichtet sein, dass das Element durch Aufwickeln einer überschüssigen Fadenlänge den Faden auf die gewünschte Länge verkürzt.
Bevorzugt ist auch die Ausgestaltung von in axialer Richtung elastischen Verankerungsfäden, diese auf Kontraktionsbewegungen des Herzens reagieren können, ohne dass eine zu große Fadenlänge vorliegt, die die Herzfunktion negativ beeinflussen könnte. Dabei ist die Faden- länge so zu wählen, dass die Elastizität nicht vollständig auf Kosten der Spannung zwischen Verankerungselementen und Herzwandung geht.
Ist das Widerlager als Fädenlängenstellelement ausgebildet, ergibt sich eine besonders vorteilhafte Ausgestaltung, da hiermit auch eine Nacheinstellung der Spannung zwischen Verankerungselementen und Widerlager, also ein Nachspannen der Verankerungsraden möglich ist, ohne dass das Herz geöffnet werden müsste.
Besonders bevorzugt ist die Struktur des Mitralklappenstents in der Ebene des Mitralklappe- nannulus im Wesentlichen oval oder U-förmig ausgebildet, dass kein Druck auf den LVOT (Left Ventrikulär Outflow Tract; linksventrikulärer Ausflusstrakt) und/oder Aortenannulus ausgeübt wird und damit eine Beeinträchtigung der Herzfunktion unterbleibt (Ma L, Tozzi P, Huber CH, Taub S5 Gerelle G, von Segesser LK. Double-crowned valved Stents for off-pump mitral valve replacement. Eur J Cardiothorac Surg. 2005 Aug; 28(2): 194-8; discussion 198- 9.). Auch bleibt der subvalvuläre Apparat in seiner natürlichen Anatomie dadurch vollkommen erhalten und wird nicht beeinträchtigt (Boudjemline Y, Agnoletti G, Bonnet D, Behr L, Borenstein N, Sidi D, Bonhoeffer P. Steps toward the percutaneous replacement of atrioven- tricular valves an experimental study. J Am Coli Cardiol. 2005 JuI 19,46(2). -360-5).
Dieser Klappenstent erhält eine dem natürlichen Mitralklappen-Apparat vollkommen ange- passte, äußerst anschmiegende Form, so dass sich dieser konisch-zulaufende (kranial-caudale Achse) nicht ganz zirkuläre (oval-ähnlich in der transversalen Achse) Klappenstent sehr stark an die natürliche Form der Mitralklappe anlegen und anlehnen kann. Im Bereich des anterioren Mitralklappenannulus ist der Klappenstent flach und führt zu fast keinem Druck und zu keiner Einengung auf den LVOT. Im Bereich des posterioren Mitralklappenannulus ist er oval und bildet die Form des posterioren Annulus nach. Dieser Klappenstent bildet eine dünne, in der Länge (cranial-caudal) begrenzte Struktur, die sich in seiner Form vollkommen an die Mitralklappe anschmiegt und damit aussieht wie ein Negativabdruck im Bereich des natürlichen Mitralklappenannulus. Der Klappenstent berührt zwar die alte Mitralklappe und deren Annulus, jedoch belässt er diese in ihrer Anatomie fast vollkommen unverändert.
Die Erfindung wird im Folgenden anhand von in den beigefügten Zeichnungen abgebildeten besonders bevorzugten Ausführungsbeispielen näher erläutert. Es zeigen:
Fig. 1 ein bevorzugtes Ausführungsbeispiel des erfindungsgemäßen Klappenstents in einer schematischen Seitenansicht;
Fig. 2 das in Fig. 1 gezeigte Ausfuhrungsbeispiel in Draufsicht von oben;
Fig. 3 eine Draufsicht auf mehrere besonders bevorzugt ausgebildete Klappenstents nach der Erfindung;
Fig. 4 eine Draufsicht auf ein Ausfuhrungsbeispiel von unten;
Fig. 5 eine schematische Ansicht zur Verdeutlichung der minimal-invasiven Transplantation eines Mitralklappenstents nach der Erfindung in einer ersten Phase bei Einbringen des erfmdungsgemäßen Mitralklappenstents an den Transplantationsort;
Fig. 6 eine schematische Ansicht zur Verdeutlichung der minimal-invasiven Transplantation eines Mitralklappenstents nach der Erfindung in einer zweiten Phase nach Positionierung der Mitralklappe;
Fig. 7 eine schematische Ansicht zur Verdeutlichung der minimal-invasiven Transplantation eines Mitralklappenstents nach der Erfindung nach Abschluss der Fixierung der Verankerungsfäden außerhalb des Apex der linkventrikulären Herzwandung;
Fig. 8 eine schematische Ansicht einer alternativen, intracardialen Fixierung der Verankerungsfäden im Bereich der Papillarmuskeln;
Fig. 9 eine schematische Ansicht eines im Aortenannulus fixierten Herzklap- penstents nach der Erfindung;
Fig. 10 eine schematische Ansicht eines in der Pulmonalposition fixierten Herzklap- penstents nach der Erfindung;
Fig. 11 eine schematische Ansicht eines in der Trikuspidalposition fixierten Herzklappenstents nach der Erfindung;
Fig. 12 ein besonders bevorzugtes Ausfuhrungsbeispiel des erfindungsgemäßen Klappenstents in einer schematischen Seitenansicht ohne Herzklappe und Verankerungsfaden; und
Fig. 13 eine schematische, dorsale, intracardiale Ansicht eines in der Mitralposition fixierten Herzklappenstents nach der Erfindung.
Die Fig. 1 bis 11 zeigen den erfmdungsgemäßen Stent zur Implantation und Befestigung von Herzklappenprothesen in verschiedenen Ansichten zur Verdeutlichung des Aufbaus des Stents und der räumlichen Verhältnisse der einzelnen Stentabschnitte zueinander im entfalteten (Fig. 1-4 und 6-11) und im gefalteten Zustand (Fig. 5).
Fig. 1 zeigt einen faltbaren Mitralklappenstent 10 nach der Erfindung in einer perspektivi- sehen Lateralansicht. Der Stent 10 weist im Wesentlichen drei Abschnitte auf: Proximal
(supravalvulär) sind am Stent 10 kreisförmig eine Vielzahl von gezackt- oder bogenförmigen
(Fig. 3) Verankerungselementen 20 angeordnet, die den Klappenstent 10 im implantierten
Zustand supravalvulär (bzw. atrial) verankern. Distal benachbart angeordnet befindet sich der konisch- und im Querschnitt ovalartig geformte, zum LVOT bevorzugt abgeflachte Stentkör- per 30 (vgl. Fig. 2).
Der Stentkörper 30 bildet eine korb- oder trapezähnliche Figur, die sich an den Mitralklappe- nannulus anschmiegt und sich in Richtung des linken Ventrikels erstreckt. Gehalten wird dieser Stent 10 im Atrium durch seine konisch zulaufende Form und durch die atrialen Veranke-
rungselemente 20. In diesen Stentkörper 30 kann eine zwei- oder dreizipflige Klappe 50 integriert sein.
An dem Stentkörper 30 befinden sich distal (zum linken Ventrikel hin) Verankerungsfäden 40, die distal von diesem Stentkörper 30 zur Verankerung des gesamten Stents 10 eingerichtet sind. Diese Verankerungsfäden 40 sorgen für eine Verankerung in der gegenüberliegenden
Ventrikelwand oder z.B. im Bereich des Papillarmuskels (proximale, medialer oder distaler
Papillarmuskelanteil); vgl. Fig. 7 und 8. Diese Verankerungsfäden 40 können mittels eines adjustierbaren Fadenlängenstellelements 70 positioniert und mit der optimalen Länge einge- stellt werden, so dass der Herzklappenstent 10 dann fixiert und verankert werden können.
Fig. 2 zeigt den Stent 10 in einer Draufsicht. Dabei ist zu erkennen, dass der Stent 10 einen Neo-Annulus, bzw. Stentkörper 30 ausbildet, in den die Herzklappenprothese 50 eingesetzt und an dem sie befestigt werden kann. Weiterhin ist zu erkennen, dass der erfindungs gemäße Stent 10 in Bezug auf die Vielzahl von supravalvulären (atrialen) Stentbügel 20 asymmetrisch ausgebildet sein kann. Dieses ist daran zu erkennen, dass der Stentkörper 30 in dieser Abbildung ovalartig ausgebildet und an einer Seite abgeflacht, also im Wesentlichen U-förmig ausgebildet ist, so dass er an dieser abgeflachten Stelle in die Richtung des LVOTs eingesetzt werden kann. Diese Abflachung bewirkt, dass an dieser Stelle kein Druck auf den LVOT und die Aortenklappe durch den selsbstexpandierbaren Stent ausgeübt werden kann, wenn der Stent 10 z.B. in die Mitralposition eingesetzt wird. Weitere bevorzugte Ausgestaltungen des Stents 10 nach der Erfindung sind in Fig. 3 gezeigt.
Fig. 4 zeigt den erfindungsgemäßen Stent 10 in einer Unteransicht. Hieraus wird deutlich, dass sich der Durchmesser von dem atrialen Anteil zum ventrikulären Anteil des Stentkörpers
30 verringert, so dass dieser von lateral aussieht wie ein Kegelstumpf (vgl. Fig. 1). Sowohl die Befestigungselemente 20 als auch der Stentkörper 30 können mit Stoff (z.B. Kunststoff,
Perikard, PTFE oder Goretex, etc.) bezogen sein, um eine verbesserte Abdichtung zwischen der Herzklappenprothese 50, Stentkörper 30 und der umgebenden Herzstruktur zu erreichen. Diese Abdichungsmembran wird dann zwischen Herzklappenprothese 50 und Stentkörper 30
oder auf die atrialen Stentstreben 20 ein-, bzw. aufgezogen, um eine optimale Abdichtung der Klappe zwischen den beiden Herzkammern zu erreichen.
In den Fig. 5 bis 7 und 8 wird die retrograde transapikale Implantation eines Klappenstents beschrieben. Der retrograde transaortale als auch der antegrade transatriale Zugangsweg kann alternativ durchgeführt werden. Die Platzierung des Klappenstents mit einem gefalteten Klappenstent über dem alten Mitralklappen- Annulus ist in Fig. 5 gezeigt. Nach erfolgreicher Orientierung mittels Markierungen am Klappenstent 10 (nicht gezeigt) kann langsam mit der Entfaltung (z.B. bevorzugt selbstexpandierend) der atrialen Verankerungselemente 20 begon- nen werden. Die Positionierung im linken Atrium sollte so geschehen, dass die abgeflachte Seite des Stentkörpers 30 in die Richtung es LVOT (Aortenklappe) zu liegen kommt. Der Stent wird dann weiter expandiert.
Fig. 6 zeigt den expandierten Klappenstent 10 in dem links-atrioventrikularen Einflusstrakt. Verankerungsfäden 40 werden an, in oder außerhalb der Herzwand adjustiert und später - wie in Fig. 7 dargestellt — mit Hilfe des bevorzugt als Fädenlängenstellelement ausgebildeten Widerlagers 80 fixiert. Während des Adjustierens der Länge der Verankerungsfäden 40 erfolgt u.a. auch eine Visualisierung des Mitralklappenapparates (z.B. Echo, CT oder NMR), sodass der Annulus mittels des neuen Stents 10 optimal in Richtung Ventrikelwand gezogen werden kann, kein paravalvuläres Leck mehr besteht, der Stent 10 gut fixiert ist und der Mitralklap- pen-annulus und -apparat vorteilhaft die linksventrikuläre Funktion unterstützt.
Alternativ zu Fig. 7 können die Verankerungsfäden 40 auch an den Papillarmuskeln befestigt werden (siehe Fig. 8), so dass diese Fäden 40 neo-chordae darstellen und die Funktion der außer Funktion gesetzten chordae tendineae übernehmen können. Die Befestigung der Verankerungsfäden 40 an der Herzwandung erfolgt jeweils mittels eines Widerlagers 80, das als Knoten oder auch als eigenständiges Element ausgebildet sein kann. Auch ist es möglich, dass die ventrikulären Verankerungsfäden 40 nicht nur am Stentkörper 30, sondern auch an der integrierten Klappe selbst angebracht werden. Auch können diese kaudalen Verankerungsfä- den 40 an jedem anderen Punkt im Ventrikel fixiert werden.
Die Fig. 7 zeigt die vollendete Positionierung und Fixierung des Stents 10. Nach Längen und Lagebestimmung der einzelnen Verankerungsfäden 40 werden diese mittels des adjustierbaren Fadenlängenstellelements 70 z.B. in der links ventrikulären Wand fixiert. Das Fadenlän- genstellelement 70 dient der optimalen Einstellung der Länge und der Position des Klap- penstents 10 und damit der Klappenprothese 50. Unterschiedliche Fäden 40 können unterschiedliche Längen und Befestigungspositionen im Ventrikel aufweisen.
Die Fig. 9 bis 11 zeigen weitere Beispiele für den Einsatz des Herzklappenstents 10 nach der Erfindung, wobei der Stent 10 an die jeweilige Anatomie angepasst ist (für die Aorten- und Pulmonalklappenposition eine eher zirkuläre Form (vgl. Fig. 3) und für die Tricuspidalpositi- on eine eher ovale Form).
Fig. 12 zeigt ein besonders bevorzugt ausgestaltetes Ausführungsbeispiel des erfindungsgemäßen Klappenstents in einer schematischen Seitenansicht, der zur besseren Übersichtlichkeit ohne Herzklappe und Verankerungsfäden dargestellt ist.
Zur Verdeutlichung der Lage des Klappenstents aus Fig. 12 in situ zeigt Fig. 13 eine schematische, dorsale, intracardiale Ansicht eines in der Mitralposition fixierten Herzklappenstents nach der Erfindung. Beachte das gute Anschmiegen des Klappenstents an die linksatriale Umgebung. Abstände zwischen der linksatrialen Wand / Mitralannulus und dem Klappenstent werden so vermieden. Herzklappe und Verankerungsfaden zur Ventrikelspitze sind zur Vereinfachung der Darstellung weggelassen worden.
Claims
1. Herzklappenstent (10) mit einem zur Aufnahme eines Herzklappenimplantats (30) eingerichteten Abschnitt und mit einer Mehrzahl von proximal angeordneten Verankerungselementen (20),
gekennzeichnet durch
eine Mehrzahl von Verankerungsfäden (40), die mit ihrem einen Ende am Stent (10) befestigt sind, und
einem die Verankerungsfäden (40) mit ihrem anderen Ende an der distalen Herz- kammerwandung unter Ausbildung einer Spannung zwischen der Herzkammerwandung und den proximal verankerten Verankerungselementen (20) befestigenden Widerlager (80).
2. Herzklappenstent (10) nach Anspruch 1, dadurch gekennzeichnet, dass die Verankerungsfäden (40) an dem den Verankerungselementen (20) gegenüberliegenden Ende des Stentkörpers (30) befestigt sind.
3. Herzklappenstent (10) nach einem der vorhergehenden Ansprüche, gekennzeichnet durch wenigstens ein zur Längeneinstellung wenigstens eines Verankerungsfadens (40) eingerichtetes Fadenlängenstellelement (70).
4. Herzklappenstent (10) nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass das Widerlager (80) als Fadenlängenstellelement ausgebildet ist.
5. Herzklappenstent (10) nach einem der vorhergehenden Ansprüche, dadurch gekenn- zeichnet, dass das Herzklappenimplantat (30) eine Mitralklappe ist.
6. Herzklappenstent (10) nach Anspruch 4, dadurch gekennzeichnet, dass der Herzklappenstent (10) in der Ebene des Mitralklappenanrmlus im Wesentlichen oval oder U-förmig ausgebildet ist.
7. Herzklappenstent (10) nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass der Herzklappenstent (10) als Kegelstumpf ausgebildet ist.
8. Herzklappenstent (10) nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass zwischen dem Herzklappenimplantat (30) und dem Stent (10) eine Abdichtungsmembran angeordnet ist.
9. Herzklappenstent (10) nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass zwischen den Verankerungselementen (20) und dem Herzklappenimplantat (30) eine Abdichtungsmembran angeordnet ist.
10. Herzklappenstent (10) nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass wenigstens ein Verankerungselement (20) aus einer Formgedächtnislegierung besteht.
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08801319.8A EP2194925B1 (de) | 2007-09-13 | 2008-09-10 | Herzklappenstent |
US12/677,958 US20110004296A1 (en) | 2007-09-13 | 2008-09-10 | Heart Valve Stent |
ES08801319.8T ES2445589T3 (es) | 2007-09-13 | 2008-09-10 | Estente de válvula cardiaca |
US13/275,683 US9095433B2 (en) | 2007-09-13 | 2011-10-18 | Truncated cone heart valve stent |
US13/275,751 US20120035703A1 (en) | 2007-09-13 | 2011-10-18 | Truncated Conical Heart Valve Stent with Anchoring Threads and Methods of Use |
US13/464,367 US20120283824A1 (en) | 2007-09-13 | 2012-05-04 | Heart Valve Stent |
US14/465,437 US9078749B2 (en) | 2007-09-13 | 2014-08-21 | Truncated cone heart valve stent |
US14/746,381 US9254192B2 (en) | 2007-09-13 | 2015-06-22 | Truncated cone heart valve stent |
US15/018,473 US9730792B2 (en) | 2007-09-13 | 2016-02-08 | Truncated cone heart valve stent |
US15/653,653 US10456248B2 (en) | 2007-09-13 | 2017-07-19 | Truncated cone heart valve stent |
US16/565,564 US11213387B2 (en) | 2007-09-13 | 2019-09-10 | Truncated cone heart valve stent |
US17/505,734 US20220039947A1 (en) | 2007-09-13 | 2021-10-20 | Truncated Cone Heart Valve Stent |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102007043830.5 | 2007-09-13 | ||
DE102007043830A DE102007043830A1 (de) | 2007-09-13 | 2007-09-13 | Herzklappenstent |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/677,958 A-371-Of-International US20110004296A1 (en) | 2007-09-13 | 2008-09-10 | Heart Valve Stent |
US13/275,683 Continuation US9095433B2 (en) | 2007-09-13 | 2011-10-18 | Truncated cone heart valve stent |
US13/464,367 Continuation US20120283824A1 (en) | 2007-09-13 | 2012-05-04 | Heart Valve Stent |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009033469A1 true WO2009033469A1 (de) | 2009-03-19 |
Family
ID=40032389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE2008/001515 WO2009033469A1 (de) | 2007-09-13 | 2008-09-10 | Herzklappenstent |
Country Status (5)
Country | Link |
---|---|
US (10) | US20110004296A1 (de) |
EP (1) | EP2194925B1 (de) |
DE (5) | DE102007043830A1 (de) |
ES (1) | ES2445589T3 (de) |
WO (1) | WO2009033469A1 (de) |
Cited By (145)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009134701A3 (en) * | 2008-05-01 | 2010-02-11 | Edwards Lifesciences Corporation | Device and method for replacing mitral valve |
WO2011106137A1 (en) * | 2010-02-24 | 2011-09-01 | Medtronic Inc. | Mitral prosthesis |
US8323336B2 (en) | 2008-04-23 | 2012-12-04 | Medtronic, Inc. | Prosthetic heart valve devices and methods of valve replacement |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
EP2742911A1 (de) * | 2012-12-17 | 2014-06-18 | Hans Reiner Figulla | Klappenprothese zum Ersatz einer Atrioventricularklappe |
US8852272B2 (en) | 2011-08-05 | 2014-10-07 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US8870950B2 (en) | 2009-12-08 | 2014-10-28 | Mitral Tech Ltd. | Rotation-based anchoring of an implant |
US8992604B2 (en) | 2010-07-21 | 2015-03-31 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US9017399B2 (en) | 2010-07-21 | 2015-04-28 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US9023099B2 (en) | 2012-10-31 | 2015-05-05 | Medtronic Vascular Galway Limited | Prosthetic mitral valve and delivery method |
US9078749B2 (en) | 2007-09-13 | 2015-07-14 | Georg Lutter | Truncated cone heart valve stent |
US9095432B2 (en) | 1996-12-31 | 2015-08-04 | Edwards Lifesciences Pvt, Inc. | Collapsible prosthetic valve having an internal cover |
US9114008B2 (en) | 2006-12-22 | 2015-08-25 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method for making the same |
US9132006B2 (en) | 2001-10-11 | 2015-09-15 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US9168129B2 (en) | 2013-02-12 | 2015-10-27 | Edwards Lifesciences Corporation | Artificial heart valve with scalloped frame design |
US9173737B2 (en) | 2008-04-23 | 2015-11-03 | Medtronic, Inc. | Stented heart valve devices |
US9241788B2 (en) | 2001-03-23 | 2016-01-26 | Edwards Lifesciences Corporation | Method for treating an aortic valve |
US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US9333074B2 (en) | 2009-04-15 | 2016-05-10 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US9364354B2 (en) | 2000-03-27 | 2016-06-14 | Neovasc Medical Ltd | Methods for treating abnormal growths in the body using a flow reducing implant |
US9364325B2 (en) | 2008-08-22 | 2016-06-14 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery system and method |
US9375312B2 (en) | 2010-07-09 | 2016-06-28 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9456896B2 (en) | 2008-09-29 | 2016-10-04 | Edwards Lifesciences Cardiaq Llc | Body cavity prosthesis |
EP2991588A4 (de) * | 2013-05-03 | 2016-10-26 | Cormatrix Cardiovascular Inc | Prothesengewebeklappen und verfahren zur verankerung davon an kardiovaskulären strukturen |
US9480560B2 (en) | 2009-09-29 | 2016-11-01 | Edwards Lifesciences Cardiaq Llc | Method of securing an intralumenal frame assembly |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9561101B2 (en) | 2008-06-20 | 2017-02-07 | Edwards Lifesciences Corporation | Two-part prosthetic valve system |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US9597183B2 (en) | 2008-10-01 | 2017-03-21 | Edwards Lifesciences Cardiaq Llc | Delivery system for vascular implant |
US9622863B2 (en) | 2013-11-22 | 2017-04-18 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
US9662204B2 (en) | 2008-06-06 | 2017-05-30 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US9681952B2 (en) | 2013-01-24 | 2017-06-20 | Mitraltech Ltd. | Anchoring of prosthetic valve supports |
US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
US9717594B2 (en) | 2009-07-14 | 2017-08-01 | Edwards Lifesciences Corporation | Methods of valve delivery on a beating heart |
US9730791B2 (en) | 2013-03-14 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US9744059B2 (en) | 2003-11-19 | 2017-08-29 | Neovasc Medical Ltd. | Vascular implant |
US9757229B2 (en) | 2011-12-09 | 2017-09-12 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
CN107157622A (zh) * | 2015-03-26 | 2017-09-15 | 杭州启明医疗器械有限公司 | 使用安全的瓣膜支架以及具有该瓣膜支架的瓣膜置换装置 |
US9763657B2 (en) | 2010-07-21 | 2017-09-19 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
USD800908S1 (en) | 2016-08-10 | 2017-10-24 | Mitraltech Ltd. | Prosthetic valve element |
US9867700B2 (en) | 2013-05-20 | 2018-01-16 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US9901444B2 (en) | 2013-12-17 | 2018-02-27 | Edwards Lifesciences Corporation | Inverted valve structure |
USD815744S1 (en) | 2016-04-28 | 2018-04-17 | Edwards Lifesciences Cardiaq Llc | Valve frame for a delivery system |
US9949827B2 (en) | 2009-09-29 | 2018-04-24 | Edwards Lifesciences Cardiaq Llc | Replacement heart valves, delivery devices and methods |
US9974650B2 (en) | 2015-07-14 | 2018-05-22 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9974651B2 (en) | 2015-02-05 | 2018-05-22 | Mitral Tech Ltd. | Prosthetic valve with axially-sliding frames |
US9974669B2 (en) | 2005-11-10 | 2018-05-22 | Edwards Lifesciences Cardiaq Llc | Percutaneous heart valve |
US10010414B2 (en) | 2014-06-06 | 2018-07-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US10016276B2 (en) | 2012-11-21 | 2018-07-10 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic heart valves |
US10022220B2 (en) | 2000-04-06 | 2018-07-17 | Edwards Lifesciences Corporation | Methods of implanting minimally-invasive prosthetic heart valves |
US10039637B2 (en) | 2015-02-11 | 2018-08-07 | Edwards Lifesciences Corporation | Heart valve docking devices and implanting methods |
US10052198B2 (en) | 2013-08-14 | 2018-08-21 | Mitral Valve Technologies Sarl | Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device |
US10052199B2 (en) | 2014-02-21 | 2018-08-21 | Mitral Valve Technologies Sarl | Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device |
US10058420B2 (en) | 2014-02-18 | 2018-08-28 | Edwards Lifesciences Corporation | Flexible commissure frame |
US10092400B2 (en) | 2015-06-23 | 2018-10-09 | Edwards Lifesciences Cardiaq Llc | Systems and methods for anchoring and sealing a prosthetic heart valve |
US10098734B2 (en) | 2013-12-05 | 2018-10-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10117744B2 (en) | 2015-08-26 | 2018-11-06 | Edwards Lifesciences Cardiaq Llc | Replacement heart valves and methods of delivery |
US10154900B2 (en) | 2003-10-02 | 2018-12-18 | Edwards Lifesciences Corporation | Implantable prosthetic valve with non-laminar flow |
US10179047B2 (en) | 2011-07-27 | 2019-01-15 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US10179043B2 (en) | 2016-02-12 | 2019-01-15 | Edwards Lifesciences Corporation | Prosthetic heart valve having multi-level sealing member |
US10195025B2 (en) | 2014-05-12 | 2019-02-05 | Edwards Lifesciences Corporation | Prosthetic heart valve |
USD841813S1 (en) | 2017-08-03 | 2019-02-26 | Cardiovalve Ltd. | Prosthetic heart valve element |
US10226335B2 (en) | 2015-06-22 | 2019-03-12 | Edwards Lifesciences Cardiaq Llc | Actively controllable heart valve implant and method of controlling same |
US10226330B2 (en) | 2013-08-14 | 2019-03-12 | Mitral Valve Technologies Sarl | Replacement heart valve apparatus and methods |
US10231834B2 (en) | 2015-02-09 | 2019-03-19 | Edwards Lifesciences Corporation | Low profile transseptal catheter and implant system for minimally invasive valve procedure |
US10232564B2 (en) | 2015-04-29 | 2019-03-19 | Edwards Lifesciences Corporation | Laminated sealing member for prosthetic heart valve |
US10238514B2 (en) | 2011-10-21 | 2019-03-26 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10245143B2 (en) | 2011-08-05 | 2019-04-02 | Cardiovalve Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US10307250B2 (en) | 2011-12-14 | 2019-06-04 | Edwards Lifesciences Corporation | System and method for crimping a prosthetic heart valve |
US10314703B2 (en) | 2015-09-21 | 2019-06-11 | Edwards Lifesciences Corporation | Cylindrical implant and balloon |
US10327896B2 (en) | 2015-04-10 | 2019-06-25 | Edwards Lifesciences Corporation | Expandable sheath with elastomeric cross sectional portions |
US10350066B2 (en) | 2015-08-28 | 2019-07-16 | Edwards Lifesciences Cardiaq Llc | Steerable delivery system for replacement mitral valve and methods of use |
US10350065B2 (en) | 2006-07-28 | 2019-07-16 | Edwards Lifesciences Cardiaq Llc | Percutaneous valve prosthesis and system and method for implanting the same |
US10350062B2 (en) | 2016-07-21 | 2019-07-16 | Edwards Lifesciences Corporation | Replacement heart valve prosthesis |
EP2861186B1 (de) | 2012-06-19 | 2019-07-24 | Boston Scientific Scimed, Inc. | Herzklappenersatz |
US10376361B2 (en) | 2011-08-05 | 2019-08-13 | Cardiovalve Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US10376363B2 (en) | 2015-04-30 | 2019-08-13 | Edwards Lifesciences Cardiaq Llc | Replacement mitral valve, delivery system for replacement mitral valve and methods of use |
US10390952B2 (en) | 2015-02-05 | 2019-08-27 | Cardiovalve Ltd. | Prosthetic valve with flexible tissue anchor portions |
US10413406B2 (en) | 2007-12-14 | 2019-09-17 | Edwards Lifesciences Corporation | Leaflet attachment frame for a prosthetic valve |
US10433959B2 (en) | 2010-10-05 | 2019-10-08 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10441416B2 (en) | 2015-04-21 | 2019-10-15 | Edwards Lifesciences Corporation | Percutaneous mitral valve replacement device |
US10463484B2 (en) | 2016-11-17 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic heart valve having leaflet inflow below frame |
US10478295B2 (en) | 2011-10-21 | 2019-11-19 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10485660B2 (en) | 2010-06-21 | 2019-11-26 | Edwards Lifesciences Cardiaq Llc | Replacement heart valve |
US10492908B2 (en) | 2014-07-30 | 2019-12-03 | Cardiovalve Ltd. | Anchoring of a prosthetic valve |
US10500047B2 (en) | 2010-07-23 | 2019-12-10 | Edwards Lifesciences Corporation | Methods for delivering prosthetic valves to native heart valves |
US10507097B2 (en) | 2006-07-31 | 2019-12-17 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US10517722B2 (en) | 2016-03-24 | 2019-12-31 | Edwards Lifesciences Corporation | Delivery system for prosthetic heart valve |
US10531866B2 (en) | 2016-02-16 | 2020-01-14 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
US10561494B2 (en) | 2011-02-25 | 2020-02-18 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US10568732B2 (en) | 2009-07-02 | 2020-02-25 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US10575948B2 (en) | 2017-08-03 | 2020-03-03 | Cardiovalve Ltd. | Prosthetic heart valve |
US10575944B2 (en) | 2016-09-22 | 2020-03-03 | Edwards Lifesciences Corporation | Prosthetic heart valve with reduced stitching |
US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
US10583000B2 (en) | 2013-03-14 | 2020-03-10 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US10603165B2 (en) | 2016-12-06 | 2020-03-31 | Edwards Lifesciences Corporation | Mechanically expanding heart valve and delivery apparatus therefor |
US10639143B2 (en) | 2016-08-26 | 2020-05-05 | Edwards Lifesciences Corporation | Multi-portion replacement heart valve prosthesis |
US10646340B2 (en) | 2016-08-19 | 2020-05-12 | Edwards Lifesciences Corporation | Steerable delivery system for replacement mitral valve |
US10687968B2 (en) | 2006-07-31 | 2020-06-23 | Edwards Lifesciences Cardiaq Llc | Sealable endovascular implants and methods for their use |
US10722353B2 (en) | 2017-08-21 | 2020-07-28 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10758348B2 (en) | 2016-11-02 | 2020-09-01 | Edwards Lifesciences Corporation | Supra and sub-annular mitral valve delivery system |
US10792471B2 (en) | 2015-04-10 | 2020-10-06 | Edwards Lifesciences Corporation | Expandable sheath |
US10813757B2 (en) | 2017-07-06 | 2020-10-27 | Edwards Lifesciences Corporation | Steerable rail delivery system |
US10856975B2 (en) | 2016-08-10 | 2020-12-08 | Cardiovalve Ltd. | Prosthetic valve with concentric frames |
US10869759B2 (en) | 2017-06-05 | 2020-12-22 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US10874508B2 (en) | 2011-10-21 | 2020-12-29 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10888421B2 (en) | 2017-09-19 | 2021-01-12 | Cardiovalve Ltd. | Prosthetic heart valve with pouch |
US10898319B2 (en) | 2017-08-17 | 2021-01-26 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10918473B2 (en) | 2017-07-18 | 2021-02-16 | Edwards Lifesciences Corporation | Transcatheter heart valve storage container and crimping mechanism |
US10932903B2 (en) | 2017-08-15 | 2021-03-02 | Edwards Lifesciences Corporation | Skirt assembly for implantable prosthetic valve |
US10973629B2 (en) | 2017-09-06 | 2021-04-13 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10973631B2 (en) | 2016-11-17 | 2021-04-13 | Edwards Lifesciences Corporation | Crimping accessory device for a prosthetic valve |
US10973628B2 (en) | 2017-08-18 | 2021-04-13 | Edwards Lifesciences Corporation | Pericardial sealing member for prosthetic heart valve |
US11013600B2 (en) | 2017-01-23 | 2021-05-25 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11013595B2 (en) | 2017-08-11 | 2021-05-25 | Edwards Lifesciences Corporation | Sealing element for prosthetic heart valve |
US11026785B2 (en) | 2017-06-05 | 2021-06-08 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US11026781B2 (en) | 2017-05-22 | 2021-06-08 | Edwards Lifesciences Corporation | Valve anchor and installation method |
US11051934B2 (en) | 2018-02-28 | 2021-07-06 | Edwards Lifesciences Corporation | Prosthetic mitral valve with improved anchors and seal |
US11058536B2 (en) | 2004-10-02 | 2021-07-13 | Edwards Lifesciences Cardiaq Llc | Method for replacement of heart valve |
US11083575B2 (en) | 2017-08-14 | 2021-08-10 | Edwards Lifesciences Corporation | Heart valve frame design with non-uniform struts |
US11096781B2 (en) | 2016-08-01 | 2021-08-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11109964B2 (en) | 2010-03-10 | 2021-09-07 | Cardiovalve Ltd. | Axially-shortening prosthetic valve |
US11135056B2 (en) | 2017-05-15 | 2021-10-05 | Edwards Lifesciences Corporation | Devices and methods of commissure formation for prosthetic heart valve |
US11147667B2 (en) | 2017-09-08 | 2021-10-19 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11185406B2 (en) | 2017-01-23 | 2021-11-30 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11246704B2 (en) | 2017-08-03 | 2022-02-15 | Cardiovalve Ltd. | Prosthetic heart valve |
US11259920B2 (en) | 2015-11-03 | 2022-03-01 | Edwards Lifesciences Corporation | Adapter for prosthesis delivery device and methods of use |
US11291546B2 (en) | 2011-08-05 | 2022-04-05 | Cardiovalve Ltd. | Leaflet clip with collars |
US11318011B2 (en) | 2018-04-27 | 2022-05-03 | Edwards Lifesciences Corporation | Mechanically expandable heart valve with leaflet clamps |
US11382746B2 (en) | 2017-12-13 | 2022-07-12 | Cardiovalve Ltd. | Prosthetic valve and delivery tool therefor |
US11395751B2 (en) | 2013-11-11 | 2022-07-26 | Edwards Lifesciences Cardiaq Llc | Systems and methods for manufacturing a stent frame |
US11399932B2 (en) | 2019-03-26 | 2022-08-02 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11406493B2 (en) | 2014-09-12 | 2022-08-09 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
US11446141B2 (en) | 2018-10-19 | 2022-09-20 | Edwards Lifesciences Corporation | Prosthetic heart valve having non-cylindrical frame |
US11633277B2 (en) | 2018-01-10 | 2023-04-25 | Cardiovalve Ltd. | Temperature-control during crimping of an implant |
US11653910B2 (en) | 2010-07-21 | 2023-05-23 | Cardiovalve Ltd. | Helical anchor implantation |
US11654023B2 (en) | 2017-01-23 | 2023-05-23 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11723783B2 (en) | 2019-01-23 | 2023-08-15 | Neovasc Medical Ltd. | Covered flow modifying apparatus |
US11730589B2 (en) | 2010-03-05 | 2023-08-22 | Edwards Lifesciences Corporation | Prosthetic heart valve having an inner frame and an outer frame |
US11779742B2 (en) | 2019-05-20 | 2023-10-10 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
US11793633B2 (en) | 2017-08-03 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic heart valve |
US11883281B2 (en) | 2017-05-31 | 2024-01-30 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11957576B2 (en) | 2008-10-10 | 2024-04-16 | Edwards Lifesciences Corporation | Expandable sheath for introducing an endovascular delivery device into a body |
US11963871B2 (en) | 2020-06-18 | 2024-04-23 | Edwards Lifesciences Corporation | Crimping devices and methods |
Families Citing this family (141)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8029556B2 (en) * | 2006-10-04 | 2011-10-04 | Edwards Lifesciences Corporation | Method and apparatus for reshaping a ventricle |
US9456812B2 (en) | 2006-11-07 | 2016-10-04 | Corvia Medical, Inc. | Devices for retrieving a prosthesis |
US10413284B2 (en) | 2006-11-07 | 2019-09-17 | Corvia Medical, Inc. | Atrial pressure regulation with control, sensing, monitoring and therapy delivery |
US9232997B2 (en) | 2006-11-07 | 2016-01-12 | Corvia Medical, Inc. | Devices and methods for retrievable intra-atrial implants |
EP3329860A1 (de) | 2006-11-07 | 2018-06-06 | David Stephen Celermajer | Vorrichtungen zur behandlung von herzversagen |
US20110257723A1 (en) | 2006-11-07 | 2011-10-20 | Dc Devices, Inc. | Devices and methods for coronary sinus pressure relief |
DE102007019058A1 (de) * | 2007-04-23 | 2008-10-30 | Stengel, Max, Dr.Dr. | Gefäßimplantat zur Behandlung eines Aneurysmas |
US9757107B2 (en) | 2009-09-04 | 2017-09-12 | Corvia Medical, Inc. | Methods and devices for intra-atrial shunts having adjustable sizes |
US20200352715A1 (en) * | 2009-10-06 | 2020-11-12 | Adam Groothuis | Systems and methods for treating luminal valves |
US8449599B2 (en) | 2009-12-04 | 2013-05-28 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
WO2011072084A2 (en) * | 2009-12-08 | 2011-06-16 | Avalon Medical Ltd. | Device and system for transcatheter mitral valve replacement |
US10058323B2 (en) | 2010-01-22 | 2018-08-28 | 4 Tech Inc. | Tricuspid valve repair using tension |
US8475525B2 (en) * | 2010-01-22 | 2013-07-02 | 4Tech Inc. | Tricuspid valve repair using tension |
US9307980B2 (en) | 2010-01-22 | 2016-04-12 | 4Tech Inc. | Tricuspid valve repair using tension |
WO2011094521A2 (en) * | 2010-01-29 | 2011-08-04 | Dc Devices, Inc. | Devices and methods for reducing venous pressure |
US9579193B2 (en) * | 2010-09-23 | 2017-02-28 | Transmural Systems Llc | Methods and systems for delivering prostheses using rail techniques |
US9005279B2 (en) * | 2010-11-12 | 2015-04-14 | Shlomo Gabbay | Beating heart buttress and implantation method to prevent prolapse of a heart valve |
WO2012087842A1 (en) | 2010-12-23 | 2012-06-28 | The Foundry, Llc | System for mitral valve repair and replacement |
EP2478868A1 (de) * | 2011-01-25 | 2012-07-25 | The Provost, Fellows, Foundation Scholars, and the other Members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth | Implantationsvorrichtung |
WO2012109557A2 (en) | 2011-02-10 | 2012-08-16 | Dc Devices, Inc. | Apparatus and methods to create and maintain an intra-atrial pressure relief opening |
US8454656B2 (en) * | 2011-03-01 | 2013-06-04 | Medtronic Ventor Technologies Ltd. | Self-suturing anchors |
WO2012127309A1 (en) | 2011-03-21 | 2012-09-27 | Ontorfano Matteo | Disk-based valve apparatus and method for the treatment of valve dysfunction |
EP3964176A1 (de) | 2011-06-21 | 2022-03-09 | Twelve, Inc. | Herzklappenprothesenvorrichtungen |
EP3403616B1 (de) | 2011-08-11 | 2022-05-11 | Tendyne Holdings, Inc. | Verbesserungen für prothesenklappen und damit zusammenhängende erfindungen |
EP4252714A3 (de) | 2011-10-19 | 2023-12-20 | Twelve, Inc. | Vorrichtung für den ersatz einer herzklappe |
US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9763780B2 (en) | 2011-10-19 | 2017-09-19 | Twelve, Inc. | Devices, systems and methods for heart valve replacement |
US9655722B2 (en) | 2011-10-19 | 2017-05-23 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
WO2013059747A1 (en) | 2011-10-19 | 2013-04-25 | Foundry Newco Xii, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US11202704B2 (en) | 2011-10-19 | 2021-12-21 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9827092B2 (en) | 2011-12-16 | 2017-11-28 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
US9205236B2 (en) | 2011-12-22 | 2015-12-08 | Corvia Medical, Inc. | Methods, systems, and devices for resizable intra-atrial shunts |
US9005155B2 (en) | 2012-02-03 | 2015-04-14 | Dc Devices, Inc. | Devices and methods for treating heart failure |
US9579198B2 (en) | 2012-03-01 | 2017-02-28 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
US9999501B2 (en) | 2012-04-18 | 2018-06-19 | Medtronic CV Luxembourg S.a.r.l. | Valve prosthesis |
US10588611B2 (en) | 2012-04-19 | 2020-03-17 | Corvia Medical Inc. | Implant retention attachment and method of use |
US9427315B2 (en) | 2012-04-19 | 2016-08-30 | Caisson Interventional, LLC | Valve replacement systems and methods |
US9011515B2 (en) | 2012-04-19 | 2015-04-21 | Caisson Interventional, LLC | Heart valve assembly systems and methods |
US8961594B2 (en) | 2012-05-31 | 2015-02-24 | 4Tech Inc. | Heart valve repair system |
US9649480B2 (en) | 2012-07-06 | 2017-05-16 | Corvia Medical, Inc. | Devices and methods of treating or ameliorating diastolic heart failure through pulmonary valve intervention |
WO2014022124A1 (en) | 2012-07-28 | 2014-02-06 | Tendyne Holdings, Inc. | Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
WO2014021905A1 (en) | 2012-07-30 | 2014-02-06 | Tendyne Holdings, Inc. | Improved delivery systems and methods for transcatheter prosthetic valves |
US9232995B2 (en) * | 2013-01-08 | 2016-01-12 | Medtronic, Inc. | Valve prosthesis and method for delivery |
US8628571B1 (en) | 2012-11-13 | 2014-01-14 | Mitraltech Ltd. | Percutaneously-deliverable mechanical valve |
DE102012022762A1 (de) * | 2012-11-22 | 2014-05-22 | Mann+Hummel Gmbh | Kraftstoffbereitstellungssystem für ein Fahrzeug mit Brennkraftmaschine |
US9788948B2 (en) | 2013-01-09 | 2017-10-17 | 4 Tech Inc. | Soft tissue anchors and implantation techniques |
US9775636B2 (en) | 2013-03-12 | 2017-10-03 | Corvia Medical, Inc. | Devices, systems, and methods for treating heart failure |
JP6329570B2 (ja) | 2013-03-14 | 2018-05-23 | 4テック インコーポレイテッド | テザーインターフェースを有するステント |
US9486306B2 (en) | 2013-04-02 | 2016-11-08 | Tendyne Holdings, Inc. | Inflatable annular sealing device for prosthetic mitral valve |
US10463489B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
WO2015065646A1 (en) | 2013-10-28 | 2015-05-07 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US11224510B2 (en) | 2013-04-02 | 2022-01-18 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10478293B2 (en) | 2013-04-04 | 2019-11-19 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
CN108294846A (zh) | 2013-05-20 | 2018-07-20 | 托尔福公司 | 可植入心脏瓣膜装置、二尖瓣修复装置以及相关系统和方法 |
US9610159B2 (en) | 2013-05-30 | 2017-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
WO2014210124A1 (en) | 2013-06-25 | 2014-12-31 | Mark Christianson | Thrombus management and structural compliance features for prosthetic heart valves |
US9561103B2 (en) | 2013-07-17 | 2017-02-07 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
CA2916955A1 (en) | 2013-07-26 | 2015-01-29 | Impala, Inc. | Systems and methods for sealing openings in an anatomical wall |
CA2919379C (en) | 2013-08-01 | 2021-03-30 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
WO2015058039A1 (en) | 2013-10-17 | 2015-04-23 | Robert Vidlund | Apparatus and methods for alignment and deployment of intracardiac devices |
US9421094B2 (en) | 2013-10-23 | 2016-08-23 | Caisson Interventional, LLC | Methods and systems for heart valve therapy |
US9526611B2 (en) | 2013-10-29 | 2016-12-27 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
WO2015063580A2 (en) | 2013-10-30 | 2015-05-07 | 4Tech Inc. | Multiple anchoring-point tension system |
US10022114B2 (en) | 2013-10-30 | 2018-07-17 | 4Tech Inc. | Percutaneous tether locking |
US10052095B2 (en) | 2013-10-30 | 2018-08-21 | 4Tech Inc. | Multiple anchoring-point tension system |
WO2015079443A1 (en) * | 2013-11-28 | 2015-06-04 | Mvalve Technologies Ltd. | Intracardiac devices comprising stabilizing elements having improved fatigue resistance |
WO2015120122A2 (en) | 2014-02-05 | 2015-08-13 | Robert Vidlund | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
US9986993B2 (en) * | 2014-02-11 | 2018-06-05 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
USD755384S1 (en) | 2014-03-05 | 2016-05-03 | Edwards Lifesciences Cardiaq Llc | Stent |
EP3116409B1 (de) | 2014-03-10 | 2023-07-26 | Tendyne Holdings, Inc. | Vorrichtungen zur positionierung und überwachung der gurtbelastung für eine künstliche mitralklappe |
US10675450B2 (en) | 2014-03-12 | 2020-06-09 | Corvia Medical, Inc. | Devices and methods for treating heart failure |
US9974647B2 (en) | 2014-06-12 | 2018-05-22 | Caisson Interventional, LLC | Two stage anchor and mitral valve assembly |
JP6559161B2 (ja) | 2014-06-19 | 2019-08-14 | 4テック インコーポレイテッド | 心臓組織の緊締 |
CA2955389C (en) | 2014-07-23 | 2023-04-04 | Corvia Medical, Inc. | Devices and methods for treating heart failure |
GB2536538B (en) | 2014-09-17 | 2018-07-18 | Cardiomech As | Anchor for implantation in body tissue |
US9750605B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
US9750607B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
US9907547B2 (en) | 2014-12-02 | 2018-03-06 | 4Tech Inc. | Off-center tissue anchors |
US9439757B2 (en) | 2014-12-09 | 2016-09-13 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
CN107405195B (zh) | 2015-01-07 | 2020-09-08 | 坦迪尼控股股份有限公司 | 人造二尖瓣以及用于递送人造二尖瓣的设备和方法 |
AU2016215197B2 (en) | 2015-02-05 | 2020-01-02 | Tendyne Holdings Inc. | Expandable epicardial pads and devices and methods for their delivery |
EP3270827B1 (de) | 2015-03-19 | 2023-12-20 | Caisson Interventional, LLC | Systeme für herzklappentherapie |
US10010417B2 (en) | 2015-04-16 | 2018-07-03 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10064718B2 (en) | 2015-04-16 | 2018-09-04 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
JP6694948B2 (ja) | 2015-04-16 | 2020-05-20 | テンダイン ホールディングス,インコーポレイテッド | 経カテーテル人工弁の送達、再配置及び回収のための装置及び方法 |
US10610249B2 (en) | 2015-04-30 | 2020-04-07 | Septulus Ab | Tissue cutting device and system |
AU2016262564B2 (en) | 2015-05-14 | 2020-11-05 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
EP3294220B1 (de) | 2015-05-14 | 2023-12-06 | Cephea Valve Technologies, Inc. | Vorrichtungen und systeme zur herzklappenfreisetzung |
CN111658234B (zh) | 2015-08-21 | 2023-03-10 | 托尔福公司 | 可植入心脏瓣膜装置、二尖瓣修复装置以及相关系统和方法 |
US10327894B2 (en) | 2015-09-18 | 2019-06-25 | Tendyne Holdings, Inc. | Methods for delivery of prosthetic mitral valves |
AU2016362474B2 (en) | 2015-12-03 | 2021-04-22 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves |
CA3006010C (en) | 2015-12-28 | 2023-09-26 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
AU2016380345B2 (en) | 2015-12-30 | 2021-10-28 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
EP4183372A1 (de) | 2016-01-29 | 2023-05-24 | Neovasc Tiara Inc. | Klappenprothese zur vermeidung von abflussverstopfung |
EP3448316B1 (de) * | 2016-04-29 | 2023-03-29 | Medtronic Vascular Inc. | Herzklappenprothesenvorrichtungen mit angebundenen ankern |
US10470877B2 (en) | 2016-05-03 | 2019-11-12 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
JP6987790B2 (ja) * | 2016-06-02 | 2022-01-05 | メドトロニック ヴァスキュラー インコーポレイテッド | 隔壁貫通孔閉鎖先端アセンブリを備えた経カテーテル弁送達システム |
EP3468480B1 (de) | 2016-06-13 | 2023-01-11 | Tendyne Holdings, Inc. | Sequenzielle freisetzung einer zweiteiligen mitralklappenprothese |
WO2017218877A1 (en) | 2016-06-17 | 2017-12-21 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
EP3478224B1 (de) | 2016-06-30 | 2022-11-02 | Tendyne Holdings, Inc. | Herzklappenprothesen sowie vorrichtung zur einführung davon |
WO2018013515A1 (en) | 2016-07-12 | 2018-01-18 | Tendyne Holdings, Inc. | Apparatus and methods for trans-septal retrieval of prosthetic heart valves |
US11241307B2 (en) | 2016-10-13 | 2022-02-08 | Boston Scientific Scimed, Inc. | Replacement heart valve with diaphragm |
JP6949973B2 (ja) | 2016-10-23 | 2021-10-13 | サニカチャラム モハン | 心室駆出デバイス |
CA3042588A1 (en) | 2016-11-21 | 2018-05-24 | Neovasc Tiara Inc. | Methods and systems for rapid retraction of a transcatheter heart valve delivery system |
US10653523B2 (en) | 2017-01-19 | 2020-05-19 | 4C Medical Technologies, Inc. | Systems, methods and devices for delivery systems, methods and devices for implanting prosthetic heart valves |
JP7046078B2 (ja) | 2017-01-23 | 2022-04-01 | セフィア・バルブ・テクノロジーズ,インコーポレイテッド | 置換僧帽弁 |
AU2018203053B2 (en) | 2017-01-23 | 2020-03-05 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10561495B2 (en) | 2017-01-24 | 2020-02-18 | 4C Medical Technologies, Inc. | Systems, methods and devices for two-step delivery and implantation of prosthetic heart valve |
US10905550B2 (en) | 2017-02-01 | 2021-02-02 | Medtronic Vascular, Inc. | Heart valve prostheses including torque anchoring mechanisms and delivery devices for the heart valve prostheses |
WO2018178977A1 (en) * | 2017-03-27 | 2018-10-04 | Vvital Biomed Ltd. | Device and method for transcatheter mitral and tricuspid valve repair |
US11337685B2 (en) * | 2017-04-05 | 2022-05-24 | Opus Medical Therapies, LLC | Transcatheter anchoring assembly for a mitral valve, a mitral valve, and related methods |
US11103351B2 (en) * | 2017-04-05 | 2021-08-31 | Opus Medical Therapies, LLC | Transcatheter atrial sealing skirt and related method |
US10820992B2 (en) * | 2017-04-05 | 2020-11-03 | Opus Medical Therapies, LLC | Transcatheter atrial sealing skirt, anchor, and tether and methods of implantation |
CA3178029A1 (en) * | 2017-04-05 | 2018-10-11 | Opus Medical Therapies, LLC | Transcatheter atrial sealing skirt, anchor, and tether and methods of implantation |
US11123187B2 (en) * | 2017-04-05 | 2021-09-21 | Opus Medical Therapies, LLC | Transcatheter atrial anchors and methods of implantation |
US10575950B2 (en) | 2017-04-18 | 2020-03-03 | Twelve, Inc. | Hydraulic systems for delivering prosthetic heart valve devices and associated methods |
US10702378B2 (en) | 2017-04-18 | 2020-07-07 | Twelve, Inc. | Prosthetic heart valve device and associated systems and methods |
US10433961B2 (en) | 2017-04-18 | 2019-10-08 | Twelve, Inc. | Delivery systems with tethers for prosthetic heart valve devices and associated methods |
US10792151B2 (en) | 2017-05-11 | 2020-10-06 | Twelve, Inc. | Delivery systems for delivering prosthetic heart valve devices and associated methods |
US10646338B2 (en) | 2017-06-02 | 2020-05-12 | Twelve, Inc. | Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods |
US10709591B2 (en) | 2017-06-06 | 2020-07-14 | Twelve, Inc. | Crimping device and method for loading stents and prosthetic heart valves |
US10729541B2 (en) | 2017-07-06 | 2020-08-04 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US10786352B2 (en) | 2017-07-06 | 2020-09-29 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
CN111050702B (zh) | 2017-07-13 | 2022-07-05 | 坦迪尼控股股份有限公司 | 人工心脏瓣膜及用于递送人工心脏瓣膜的设备和方法 |
CN111263622A (zh) | 2017-08-25 | 2020-06-09 | 内奥瓦斯克迪亚拉公司 | 顺序展开的经导管二尖瓣假体 |
AU2018323900A1 (en) | 2017-08-28 | 2020-02-27 | Tendyne Holdings, Inc. | Prosthetic heart valves with tether coupling features |
EP3459469A1 (de) | 2017-09-23 | 2019-03-27 | Universität Zürich | Medizinische okklusionsvorrichtung |
EP3720390B1 (de) | 2018-01-25 | 2024-05-01 | Edwards Lifesciences Corporation | Einführsystem zur unterstützten rückgewinnung oder neupositionierung eines klappenersatzes nach dem einsetzen |
US11857441B2 (en) | 2018-09-04 | 2024-01-02 | 4C Medical Technologies, Inc. | Stent loading device |
CA3118599A1 (en) | 2018-11-08 | 2020-05-14 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
CN113811265A (zh) | 2019-04-01 | 2021-12-17 | 内奥瓦斯克迪亚拉公司 | 能够以可控的方式部署的假体瓣膜 |
CA3136334A1 (en) | 2019-04-10 | 2020-10-15 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
CN211049720U (zh) * | 2019-05-31 | 2020-07-21 | 先健科技(深圳)有限公司 | 心脏瓣膜假体及系统 |
CN114144144A (zh) | 2019-06-20 | 2022-03-04 | 内奥瓦斯克迪亚拉公司 | 低轮廓假体二尖瓣 |
EP4033999A2 (de) | 2019-09-26 | 2022-08-03 | Universität Zürich | Verschlussvorrichtungen für das linke herzohr |
US11648110B2 (en) | 2019-12-05 | 2023-05-16 | Tendyne Holdings, Inc. | Braided anchor for mitral valve |
US11648114B2 (en) | 2019-12-20 | 2023-05-16 | Tendyne Holdings, Inc. | Distally loaded sheath and loading funnel |
US11931253B2 (en) | 2020-01-31 | 2024-03-19 | 4C Medical Technologies, Inc. | Prosthetic heart valve delivery system: ball-slide attachment |
US11951002B2 (en) | 2020-03-30 | 2024-04-09 | Tendyne Holdings, Inc. | Apparatus and methods for valve and tether fixation |
WO2022039853A1 (en) | 2020-08-19 | 2022-02-24 | Tendyne Holdings, Inc. | Fully-transseptal apical pad with pulley for tensioning |
WO2022072687A1 (en) | 2020-10-01 | 2022-04-07 | Opus Medical Therapies, LLC | Transcatheter anchor support and methods of implantation |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10010074A1 (de) | 2000-02-28 | 2001-10-18 | Fraunhofer Ges Forschung | Vorrichtung zur Befestigung und Verankerung von Herzklappenprothesen |
DE19546692C2 (de) | 1995-12-14 | 2002-11-07 | Hans-Reiner Figulla | Selbstexpandierende Herzklappenprothese zur Implantation im menschlichen Körper über ein Kathetersystem |
US20030078652A1 (en) | 2001-10-23 | 2003-04-24 | Sutherland Fraser W.H. | Heart valve prosthesis |
EP1469797A1 (de) | 2002-08-13 | 2004-10-27 | Hans-Reiner Figulla | Vorrichtung zur implantation und befestigung von herzklappenprothesen |
US20050075727A1 (en) | 2001-10-29 | 2005-04-07 | Wheatley David John | Mitral valve prosthesis |
US20070050020A1 (en) | 2000-02-02 | 2007-03-01 | Spence Paul A | Heart valve repair apparatus and methods |
Family Cites Families (669)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US137408A (en) * | 1873-04-01 | Improvement in chain-machines | ||
US2697008A (en) | 1953-10-09 | 1954-12-14 | Globe Automatic Sprinkler Co | Sprinkler head |
DE1001074C2 (de) | 1955-05-20 | 1957-06-27 | Eisenwerke Muelheim Meiderich | Stufenlos regelbares Schaltwerksgetriebe |
GB1127325A (en) | 1965-08-23 | 1968-09-18 | Henry Berry | Improved instrument for inserting artificial heart valves |
US3587115A (en) | 1966-05-04 | 1971-06-28 | Donald P Shiley | Prosthetic sutureless heart valves and implant tools therefor |
US3472230A (en) | 1966-12-19 | 1969-10-14 | Fogarty T J | Umbrella catheter |
US3548417A (en) | 1967-09-05 | 1970-12-22 | Ronnie G Kischer | Heart valve having a flexible wall which rotates between open and closed positions |
US3476101A (en) | 1967-12-28 | 1969-11-04 | Texas Instruments Inc | Gas-fired oven |
US3671979A (en) | 1969-09-23 | 1972-06-27 | Univ Utah | Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve |
US3657744A (en) * | 1970-05-08 | 1972-04-25 | Univ Minnesota | Method for fixing prosthetic implants in a living body |
US3714671A (en) | 1970-11-30 | 1973-02-06 | Cutter Lab | Tissue-type heart valve with a graft support ring or stent |
US3755823A (en) | 1971-04-23 | 1973-09-04 | Hancock Laboratories Inc | Flexible stent for heart valve |
GB1402255A (en) | 1971-09-24 | 1975-08-06 | Smiths Industries Ltd | Medical or surgical devices of the kind having an inflatable balloon |
US3976079A (en) | 1974-08-01 | 1976-08-24 | Samuels Peter B | Securing devices for sutures |
US4003382A (en) | 1975-07-25 | 1977-01-18 | Ethicon, Inc. | Retention catheter and method of manufacture |
US4035849A (en) | 1975-11-17 | 1977-07-19 | William W. Angell | Heart valve stent and process for preparing a stented heart valve prosthesis |
CA1069652A (en) | 1976-01-09 | 1980-01-15 | Alain F. Carpentier | Supported bioprosthetic heart valve with compliant orifice ring |
US4073438A (en) | 1976-09-03 | 1978-02-14 | Nelson Irrigation Corporation | Sprinkler head |
US4056854A (en) | 1976-09-28 | 1977-11-08 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Aortic heart valve catheter |
US4297749A (en) | 1977-04-25 | 1981-11-03 | Albany International Corp. | Heart valve prosthesis |
US4222126A (en) | 1978-12-14 | 1980-09-16 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare | Unitized three leaflet heart valve |
US4265694A (en) | 1978-12-14 | 1981-05-05 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Method of making unitized three leaflet heart valve |
US4574803A (en) | 1979-01-19 | 1986-03-11 | Karl Storz | Tissue cutter |
GB2056023B (en) | 1979-08-06 | 1983-08-10 | Ross D N Bodnar E | Stent for a cardiac valve |
US4373216A (en) | 1980-10-27 | 1983-02-15 | Hemex, Inc. | Heart valves having edge-guided occluders |
US4339831A (en) | 1981-03-27 | 1982-07-20 | Medtronic, Inc. | Dynamic annulus heart valve and reconstruction ring |
US4470157A (en) | 1981-04-27 | 1984-09-11 | Love Jack W | Tricuspid prosthetic tissue heart valve |
US4345340A (en) | 1981-05-07 | 1982-08-24 | Vascor, Inc. | Stent for mitral/tricuspid heart valve |
US4406022A (en) | 1981-11-16 | 1983-09-27 | Kathryn Roy | Prosthetic valve means for cardiovascular surgery |
DE3365190D1 (en) | 1982-01-20 | 1986-09-18 | Martin Morris Black | Artificial heart valves |
SE445884B (sv) | 1982-04-30 | 1986-07-28 | Medinvent Sa | Anordning for implantation av en rorformig protes |
IT1212547B (it) | 1982-08-09 | 1989-11-30 | Iorio Domenico | Strumento di impiego chirurgico destinato a rendere piu' facili e piu' sicuri gli interventi per l'impianto di bioprotesi in organi umani |
GB8300636D0 (en) | 1983-01-11 | 1983-02-09 | Black M M | Heart valve replacements |
US4535483A (en) | 1983-01-17 | 1985-08-20 | Hemex, Inc. | Suture rings for heart valves |
US4612011A (en) | 1983-07-22 | 1986-09-16 | Hans Kautzky | Central occluder semi-biological heart valve |
US4626255A (en) | 1983-09-23 | 1986-12-02 | Christian Weinhold | Heart valve bioprothesis |
US4585705A (en) | 1983-11-09 | 1986-04-29 | Dow Corning Corporation | Hard organopolysiloxane release coating |
US4787899A (en) | 1983-12-09 | 1988-11-29 | Lazarus Harrison M | Intraluminal graft device, system and method |
US4627436A (en) | 1984-03-01 | 1986-12-09 | Innoventions Biomedical Inc. | Angioplasty catheter and method for use thereof |
US4592340A (en) | 1984-05-02 | 1986-06-03 | Boyles Paul W | Artificial catheter means |
US4883458A (en) | 1987-02-24 | 1989-11-28 | Surgical Systems & Instruments, Inc. | Atherectomy system and method of using the same |
US5007896A (en) | 1988-12-19 | 1991-04-16 | Surgical Systems & Instruments, Inc. | Rotary-catheter for atherectomy |
US4979939A (en) | 1984-05-14 | 1990-12-25 | Surgical Systems & Instruments, Inc. | Atherectomy system with a guide wire |
DE3426300A1 (de) | 1984-07-17 | 1986-01-30 | Doguhan Dr.med. 6000 Frankfurt Baykut | Zweiwegeventil und seine verwendung als herzklappenprothese |
DE3442088A1 (de) | 1984-11-17 | 1986-05-28 | Beiersdorf Ag, 2000 Hamburg | Herzklappenprothese |
SU1271508A1 (ru) | 1984-11-29 | 1986-11-23 | Горьковский государственный медицинский институт им.С.М.Кирова | Искусственный клапан сердца |
US4759758A (en) | 1984-12-07 | 1988-07-26 | Shlomo Gabbay | Prosthetic heart valve |
US4638886A (en) | 1985-10-21 | 1987-01-27 | Sta-Rite Industries, Inc. | Apparatus for disabling an obstructed lift mechanism |
US4733665C2 (en) | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
DE3640745A1 (de) | 1985-11-30 | 1987-06-04 | Ernst Peter Prof Dr M Strecker | Katheter zum herstellen oder erweitern von verbindungen zu oder zwischen koerperhohlraeumen |
CH672247A5 (de) | 1986-03-06 | 1989-11-15 | Mo Vysshee Tekhnicheskoe Uchil | |
US4878906A (en) | 1986-03-25 | 1989-11-07 | Servetus Partnership | Endoprosthesis for repairing a damaged vessel |
US4777951A (en) | 1986-09-19 | 1988-10-18 | Mansfield Scientific, Inc. | Procedure and catheter instrument for treating patients for aortic stenosis |
US4762128A (en) | 1986-12-09 | 1988-08-09 | Advanced Surgical Intervention, Inc. | Method and apparatus for treating hypertrophy of the prostate gland |
FR2611628B1 (fr) | 1987-02-26 | 1990-11-30 | Bendix France | Correcteur de freinage asservi a la charge d'un vehicule |
US4878495A (en) | 1987-05-15 | 1989-11-07 | Joseph Grayzel | Valvuloplasty device with satellite expansion means |
US4796629A (en) | 1987-06-03 | 1989-01-10 | Joseph Grayzel | Stiffened dilation balloon catheter device |
US4829990A (en) | 1987-06-25 | 1989-05-16 | Thueroff Joachim | Implantable hydraulic penile erector |
US4851001A (en) | 1987-09-17 | 1989-07-25 | Taheri Syde A | Prosthetic valve for a blood vein and an associated method of implantation of the valve |
JPH0624755Y2 (ja) | 1987-10-19 | 1994-06-29 | 日産自動車株式会社 | 座金型圧力センサ |
US5266073A (en) | 1987-12-08 | 1993-11-30 | Wall W Henry | Angioplasty stent |
US4830117A (en) | 1987-12-24 | 1989-05-16 | Fire Sprinkler Specialties, Inc. | Shut-off device for an automatic sprinkler |
US4960424A (en) | 1988-06-30 | 1990-10-02 | Grooters Ronald K | Method of replacing a defective atrio-ventricular valve with a total atrio-ventricular valve bioprosthesis |
US5032128A (en) | 1988-07-07 | 1991-07-16 | Medtronic, Inc. | Heart valve prosthesis |
DE8815082U1 (de) | 1988-11-29 | 1989-05-18 | Biotronik Mess- Und Therapiegeraete Gmbh & Co Ingenieurbuero Berlin, 1000 Berlin, De | |
US4856516A (en) | 1989-01-09 | 1989-08-15 | Cordis Corporation | Endovascular stent apparatus and method |
US4966604A (en) | 1989-01-23 | 1990-10-30 | Interventional Technologies Inc. | Expandable atherectomy cutter with flexibly bowed blades |
US4994077A (en) | 1989-04-21 | 1991-02-19 | Dobben Richard L | Artificial heart valve for implantation in a blood vessel |
US5609626A (en) | 1989-05-31 | 1997-03-11 | Baxter International Inc. | Stent devices and support/restrictor assemblies for use in conjunction with prosthetic vascular grafts |
JP3127378B2 (ja) | 1989-05-31 | 2001-01-22 | バクスター インターナショナル インコーポレーテッド | 生物学的弁補綴 |
US4923013A (en) | 1989-08-14 | 1990-05-08 | Gennaro Sergio K De | Fire sprinkler system and automatic shut-off valve therefor |
US5047041A (en) | 1989-08-22 | 1991-09-10 | Samuels Peter B | Surgical apparatus for the excision of vein valves in situ |
US4986830A (en) | 1989-09-22 | 1991-01-22 | Schneider (U.S.A.) Inc. | Valvuloplasty catheter with balloon which remains stable during inflation |
US5035706A (en) | 1989-10-17 | 1991-07-30 | Cook Incorporated | Percutaneous stent and method for retrieval thereof |
US5089015A (en) | 1989-11-28 | 1992-02-18 | Promedica International | Method for implanting unstented xenografts and allografts |
US5591185A (en) | 1989-12-14 | 1997-01-07 | Corneal Contouring Development L.L.C. | Method and apparatus for reprofiling or smoothing the anterior or stromal cornea by scraping |
US5037434A (en) | 1990-04-11 | 1991-08-06 | Carbomedics, Inc. | Bioprosthetic heart valve with elastic commissures |
US5059177A (en) | 1990-04-19 | 1991-10-22 | Cordis Corporation | Triple lumen balloon catheter |
DK124690D0 (da) | 1990-05-18 | 1990-05-18 | Henning Rud Andersen | Klapprotes til implantering i kroppen for erstatning af naturlig klap samt kateter til brug ved implantering af en saadan klapprotese |
US5085635A (en) | 1990-05-18 | 1992-02-04 | Cragg Andrew H | Valved-tip angiographic catheter |
US5411552A (en) * | 1990-05-18 | 1995-05-02 | Andersen; Henning R. | Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis |
GB9012716D0 (en) | 1990-06-07 | 1990-08-01 | Frater Robert W M | Mitral heart valve replacements |
US5064435A (en) | 1990-06-28 | 1991-11-12 | Schneider (Usa) Inc. | Self-expanding prosthesis having stable axial length |
US5336616A (en) | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
US5152771A (en) | 1990-12-31 | 1992-10-06 | The Board Of Supervisors Of Louisiana State University | Valve cutter for arterial by-pass surgery |
US5282847A (en) | 1991-02-28 | 1994-02-01 | Medtronic, Inc. | Prosthetic vascular grafts with a pleated structure |
JPH05184611A (ja) | 1991-03-19 | 1993-07-27 | Kenji Kusuhara | 弁輪支持器具及びその取り付け方法 |
US5295958A (en) | 1991-04-04 | 1994-03-22 | Shturman Cardiology Systems, Inc. | Method and apparatus for in vivo heart valve decalcification |
US5167628A (en) | 1991-05-02 | 1992-12-01 | Boyles Paul W | Aortic balloon catheter assembly for indirect infusion of the coronary arteries |
US5397351A (en) | 1991-05-13 | 1995-03-14 | Pavcnik; Dusan | Prosthetic valve for percutaneous insertion |
RO110672B1 (ro) | 1991-05-16 | 1996-03-29 | Mures Cardiovascular Research | Valva cardiaca |
US5769812A (en) * | 1991-07-16 | 1998-06-23 | Heartport, Inc. | System for cardiac procedures |
US5584803A (en) | 1991-07-16 | 1996-12-17 | Heartport, Inc. | System for cardiac procedures |
US5370685A (en) | 1991-07-16 | 1994-12-06 | Stanford Surgical Technologies, Inc. | Endovascular aortic valve replacement |
US5192297A (en) * | 1991-12-31 | 1993-03-09 | Medtronic, Inc. | Apparatus and method for placement and implantation of a stent |
US5756476A (en) | 1992-01-14 | 1998-05-26 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibition of cell proliferation using antisense oligonucleotides |
US5201880A (en) | 1992-01-27 | 1993-04-13 | Pioneering Technologies, Inc. | Mitral and tricuspid annuloplasty rings |
US5306296A (en) | 1992-08-21 | 1994-04-26 | Medtronic, Inc. | Annuloplasty and suture rings |
WO1993015690A2 (en) | 1992-01-27 | 1993-08-19 | Medtronic, Inc. | Annuloplasty and suture rings |
US5163953A (en) | 1992-02-10 | 1992-11-17 | Vince Dennis J | Toroidal artificial heart valve stent |
US5683448A (en) | 1992-02-21 | 1997-11-04 | Boston Scientific Technology, Inc. | Intraluminal stent and graft |
US5332402A (en) | 1992-05-12 | 1994-07-26 | Teitelbaum George P | Percutaneously-inserted cardiac valve |
DE4327825C2 (de) | 1992-11-24 | 1996-10-02 | Mannesmann Ag | Drosselrückschlagelement |
US5972030A (en) | 1993-02-22 | 1999-10-26 | Heartport, Inc. | Less-invasive devices and methods for treatment of cardiac valves |
US5682906A (en) * | 1993-02-22 | 1997-11-04 | Heartport, Inc. | Methods of performing intracardiac procedures on an arrested heart |
US5797960A (en) | 1993-02-22 | 1998-08-25 | Stevens; John H. | Method and apparatus for thoracoscopic intracardiac procedures |
GB9312666D0 (en) | 1993-06-18 | 1993-08-04 | Vesely Ivan | Bioprostetic heart valve |
FR2708458B1 (fr) * | 1993-08-03 | 1995-09-15 | Seguin Jacques | Anneau prothétique pour chirurgie cardiaque. |
US5607462A (en) | 1993-09-24 | 1997-03-04 | Cardiac Pathways Corporation | Catheter assembly, catheter and multi-catheter introducer for use therewith |
US5545209A (en) | 1993-09-30 | 1996-08-13 | Texas Petrodet, Inc. | Controlled deployment of a medical device |
US5480424A (en) | 1993-11-01 | 1996-01-02 | Cox; James L. | Heart valve replacement using flexible tubes |
US5609627A (en) | 1994-02-09 | 1997-03-11 | Boston Scientific Technology, Inc. | Method for delivering a bifurcated endoluminal prosthesis |
US5364407A (en) | 1994-03-21 | 1994-11-15 | Poll Wayne L | Laparoscopic suturing system |
US5728068A (en) | 1994-06-14 | 1998-03-17 | Cordis Corporation | Multi-purpose balloon catheter |
US5554185A (en) | 1994-07-18 | 1996-09-10 | Block; Peter C. | Inflatable prosthetic cardiovascular valve for percutaneous transluminal implantation of same |
US5554184A (en) | 1994-07-27 | 1996-09-10 | Machiraju; Venkat R. | Heart valve |
US5833673A (en) | 1994-11-02 | 1998-11-10 | Daig Corporation | Guiding introducer system for use in the treatment of left ventricular tachycardia |
US6335552B1 (en) * | 1995-01-31 | 2002-01-01 | Fujitsu Limited | Semiconductor device and method for fabricating the same |
US5904697A (en) | 1995-02-24 | 1999-05-18 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
US5683449A (en) | 1995-02-24 | 1997-11-04 | Marcade; Jean Paul | Modular bifurcated intraluminal grafts and methods for delivering and assembling same |
BE1009278A3 (fr) * | 1995-04-12 | 1997-01-07 | Corvita Europ | Tuteur auto-expansible pour dispositif medical a introduire dans une cavite d'un corps, et dispositif medical muni d'un tel tuteur. |
US5639274A (en) | 1995-06-02 | 1997-06-17 | Fischell; Robert E. | Integrated catheter system for balloon angioplasty and stent delivery |
US5716417A (en) | 1995-06-07 | 1998-02-10 | St. Jude Medical, Inc. | Integral supporting structure for bioprosthetic heart valve |
US5571175A (en) | 1995-06-07 | 1996-11-05 | St. Jude Medical, Inc. | Suture guard for prosthetic heart valve |
US5697905A (en) | 1995-06-19 | 1997-12-16 | Leo T. d'Ambrosio | Triple-lumen intra-aortic catheter |
US5882341A (en) | 1995-07-07 | 1999-03-16 | Bousquet; Gerald G. | Method of providing a long-lived window through the skin to subcutaneous tissue |
DE19532846A1 (de) | 1995-09-06 | 1997-03-13 | Georg Dr Berg | Ventileinrichtung |
US5735842A (en) | 1995-09-11 | 1998-04-07 | St. Jude Medical, Inc. | Low profile manipulators for heart valve prostheses |
US5662704A (en) | 1995-12-01 | 1997-09-02 | Medtronic, Inc. | Physiologic mitral valve bioprosthesis |
FR2742994B1 (fr) | 1995-12-28 | 1998-04-03 | Sgro Jean-Claude | Ensemble de traitement chirurgical d'une lumiere intracorporelle |
US5855602A (en) | 1996-09-09 | 1999-01-05 | Shelhigh, Inc. | Heart valve prosthesis |
US6402780B2 (en) | 1996-02-23 | 2002-06-11 | Cardiovascular Technologies, L.L.C. | Means and method of replacing a heart valve in a minimally invasive manner |
US5716370A (en) | 1996-02-23 | 1998-02-10 | Williamson, Iv; Warren | Means for replacing a heart valve in a minimally invasive manner |
DE69719237T2 (de) | 1996-05-23 | 2003-11-27 | Samsung Electronics Co Ltd | Flexibler, selbstexpandierbarer Stent und Verfahren zu dessen Herstellung |
US5855601A (en) * | 1996-06-21 | 1999-01-05 | The Trustees Of Columbia University In The City Of New York | Artificial heart valve and method and device for implanting the same |
DE19625202A1 (de) * | 1996-06-24 | 1998-01-02 | Adiam Medizintechnik Gmbh & Co | Prothetische Mitral-Herzklappe |
US5792179A (en) | 1996-07-16 | 1998-08-11 | Sideris; Eleftherios B. | Retrievable cardiac balloon placement |
US6217585B1 (en) * | 1996-08-16 | 2001-04-17 | Converge Medical, Inc. | Mechanical stent and graft delivery system |
AU739710B2 (en) | 1996-08-23 | 2001-10-18 | Boston Scientific Limited | Stent delivery system having stent securement apparatus |
US5968068A (en) | 1996-09-12 | 1999-10-19 | Baxter International Inc. | Endovascular delivery system |
US5968052A (en) | 1996-11-27 | 1999-10-19 | Scimed Life Systems Inc. | Pull back stent delivery system with pistol grip retraction handle |
US5749890A (en) | 1996-12-03 | 1998-05-12 | Shaknovich; Alexander | Method and system for stent placement in ostial lesions |
NL1004827C2 (nl) | 1996-12-18 | 1998-06-19 | Surgical Innovations Vof | Inrichting voor het reguleren van de bloedsomloop. |
EP0850607A1 (de) | 1996-12-31 | 1998-07-01 | Cordis Corporation | Klappenprothese zur Implantation in Körperkanälen |
US6406420B1 (en) | 1997-01-02 | 2002-06-18 | Myocor, Inc. | Methods and devices for improving cardiac function in hearts |
US6045497A (en) * | 1997-01-02 | 2000-04-04 | Myocor, Inc. | Heart wall tension reduction apparatus and method |
US6077214A (en) * | 1998-07-29 | 2000-06-20 | Myocor, Inc. | Stress reduction apparatus and method |
US6183411B1 (en) * | 1998-09-21 | 2001-02-06 | Myocor, Inc. | External stress reduction device and method |
US5906594A (en) | 1997-01-08 | 1999-05-25 | Symbiosis Corporation | Endoscopic infusion needle having dual distal stops |
GB9701479D0 (en) * | 1997-01-24 | 1997-03-12 | Aortech Europ Ltd | Heart valve |
US5957949A (en) | 1997-05-01 | 1999-09-28 | World Medical Manufacturing Corp. | Percutaneous placement valve stent |
US6206917B1 (en) | 1997-05-02 | 2001-03-27 | St. Jude Medical, Inc. | Differential treatment of prosthetic devices |
US5855597A (en) | 1997-05-07 | 1999-01-05 | Iowa-India Investments Co. Limited | Stent valve and stent graft for percutaneous surgery |
US6245102B1 (en) * | 1997-05-07 | 2001-06-12 | Iowa-India Investments Company Ltd. | Stent, stent graft and stent valve |
US5971983A (en) | 1997-05-09 | 1999-10-26 | The Regents Of The University Of California | Tissue ablation device and method of use |
US6123725A (en) | 1997-07-11 | 2000-09-26 | A-Med Systems, Inc. | Single port cardiac support apparatus |
WO1999011201A2 (en) | 1997-09-04 | 1999-03-11 | Endocore, Inc. | Artificial chordae replacement |
US6468300B1 (en) | 1997-09-23 | 2002-10-22 | Diseno Y Desarrollo Medico, S.A. De C.V. | Stent covered heterologous tissue |
US5925063A (en) * | 1997-09-26 | 1999-07-20 | Khosravi; Farhad | Coiled sheet valve, filter or occlusive device and methods of use |
US6332893B1 (en) | 1997-12-17 | 2001-12-25 | Myocor, Inc. | Valve to myocardium tension members device and method |
DE69841333D1 (de) * | 1997-12-29 | 2010-01-07 | Cleveland Clinic Foundation | System zur minimalinvasiven einführung einer herzklappen- bioprothese |
US6530952B2 (en) | 1997-12-29 | 2003-03-11 | The Cleveland Clinic Foundation | Bioprosthetic cardiovascular valve system |
EP0935978A1 (de) | 1998-02-16 | 1999-08-18 | Medicorp S.A. | Katheter zur Durchführung einer Angioplastie und zum Einbringen eines Stents |
US6540693B2 (en) | 1998-03-03 | 2003-04-01 | Senorx, Inc. | Methods and apparatus for securing medical instruments to desired locations in a patients body |
US6174327B1 (en) * | 1998-02-27 | 2001-01-16 | Scimed Life Systems, Inc. | Stent deployment apparatus and method |
EP0943300A1 (de) | 1998-03-17 | 1999-09-22 | Medicorp S.A. | Vorrichtung zum reversiblen Einbringen eines Stents |
US7060021B1 (en) | 1998-07-23 | 2006-06-13 | Wilk Patent Development Corporation | Method and device for improving cardiac function |
US6260552B1 (en) * | 1998-07-29 | 2001-07-17 | Myocor, Inc. | Transventricular implant tools and devices |
EP2111800B1 (de) | 1998-07-29 | 2016-06-15 | Edwards Lifesciences AG | Transventrikuläre Implantatwerkzeuge und Vorrichtungen |
US6334873B1 (en) | 1998-09-28 | 2002-01-01 | Autogenics | Heart valve having tissue retention with anchors and an outer sheath |
US7128073B1 (en) * | 1998-11-06 | 2006-10-31 | Ev3 Endovascular, Inc. | Method and device for left atrial appendage occlusion |
US6066160A (en) | 1998-11-23 | 2000-05-23 | Quickie Llc | Passive knotless suture terminator for use in minimally invasive surgery and to facilitate standard tissue securing |
DE19857887B4 (de) | 1998-12-15 | 2005-05-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verankerungsstütze für eine Herzklappenprothese |
FR2788217A1 (fr) | 1999-01-12 | 2000-07-13 | Brice Letac | Valvule prothetique implantable par catheterisme, ou chirurgicalement |
US6350277B1 (en) * | 1999-01-15 | 2002-02-26 | Scimed Life Systems, Inc. | Stents with temporary retaining bands |
US6896690B1 (en) | 2000-01-27 | 2005-05-24 | Viacor, Inc. | Cardiac valve procedure methods and devices |
WO2000044313A1 (en) | 1999-01-27 | 2000-08-03 | Viacor Incorporated | Cardiac valve procedure methods and devices |
US6425916B1 (en) | 1999-02-10 | 2002-07-30 | Michi E. Garrison | Methods and devices for implanting cardiac valves |
DE19907646A1 (de) | 1999-02-23 | 2000-08-24 | Georg Berg | Ventileinrichtung zum Einsetzen in ein Hohlorgan |
US6210408B1 (en) * | 1999-02-24 | 2001-04-03 | Scimed Life Systems, Inc. | Guide wire system for RF recanalization of vascular blockages |
US6752813B2 (en) | 1999-04-09 | 2004-06-22 | Evalve, Inc. | Methods and devices for capturing and fixing leaflets in valve repair |
ATE492219T1 (de) * | 1999-04-09 | 2011-01-15 | Evalve Inc | Vorrichtung zur herzklappenoperation |
US6231602B1 (en) * | 1999-04-16 | 2001-05-15 | Edwards Lifesciences Corporation | Aortic annuloplasty ring |
US6790229B1 (en) * | 1999-05-25 | 2004-09-14 | Eric Berreklouw | Fixing device, in particular for fixing to vascular wall tissue |
US6287339B1 (en) | 1999-05-27 | 2001-09-11 | Sulzer Carbomedics Inc. | Sutureless heart valve prosthesis |
EP1057460A1 (de) | 1999-06-01 | 2000-12-06 | Numed, Inc. | Ersatzventileinrichtung und Verfahren zu ihrer Implantierung |
US7416554B2 (en) | 2002-12-11 | 2008-08-26 | Usgi Medical Inc | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US7192442B2 (en) | 1999-06-30 | 2007-03-20 | Edwards Lifesciences Ag | Method and device for treatment of mitral insufficiency |
US6312465B1 (en) | 1999-07-23 | 2001-11-06 | Sulzer Carbomedics Inc. | Heart valve prosthesis with a resiliently deformable retaining member |
US7674222B2 (en) * | 1999-08-09 | 2010-03-09 | Cardiokinetix, Inc. | Cardiac device and methods of use thereof |
US6299637B1 (en) | 1999-08-20 | 2001-10-09 | Samuel M. Shaolian | Transluminally implantable venous valve |
IT1307268B1 (it) | 1999-09-30 | 2001-10-30 | Sorin Biomedica Cardio Spa | Dispositivo per interventi di riparazione o sostituzione valvolarecardiaca. |
US6371983B1 (en) | 1999-10-04 | 2002-04-16 | Ernest Lane | Bioprosthetic heart valve |
US8632590B2 (en) | 1999-10-20 | 2014-01-21 | Anulex Technologies, Inc. | Apparatus and methods for the treatment of the intervertebral disc |
US6440164B1 (en) | 1999-10-21 | 2002-08-27 | Scimed Life Systems, Inc. | Implantable prosthetic valve |
FR2815844B1 (fr) | 2000-10-31 | 2003-01-17 | Jacques Seguin | Support tubulaire de mise en place, par voie percutanee, d'une valve cardiaque de remplacement |
US7018406B2 (en) | 1999-11-17 | 2006-03-28 | Corevalve Sa | Prosthetic valve for transluminal delivery |
FR2800984B1 (fr) | 1999-11-17 | 2001-12-14 | Jacques Seguin | Dispositif de remplacement d'une valve cardiaque par voie percutanee |
DE19955490A1 (de) | 1999-11-18 | 2001-06-13 | Thermamed Gmbh | Medizintechnische Wärmevorrichtung |
US7195641B2 (en) * | 1999-11-19 | 2007-03-27 | Advanced Bio Prosthetic Surfaces, Ltd. | Valvular prostheses having metal or pseudometallic construction and methods of manufacture |
US6458153B1 (en) | 1999-12-31 | 2002-10-01 | Abps Venture One, Ltd. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US8241274B2 (en) | 2000-01-19 | 2012-08-14 | Medtronic, Inc. | Method for guiding a medical device |
DK1251804T3 (da) | 2000-01-27 | 2008-11-03 | 3F Therapeutics Inc | Hjerteklapventil |
DE60128069D1 (de) | 2000-01-31 | 2007-06-06 | Cook Biotech Inc | Stentventilklappen |
US6402781B1 (en) | 2000-01-31 | 2002-06-11 | Mitralife | Percutaneous mitral annuloplasty and cardiac reinforcement |
US6989028B2 (en) | 2000-01-31 | 2006-01-24 | Edwards Lifesciences Ag | Medical system and method for remodeling an extravascular tissue structure |
DE60111184T2 (de) | 2000-02-02 | 2005-10-27 | Robert V. Snyders | Künstiche herzklappe |
DE10007701C2 (de) | 2000-02-19 | 2002-01-31 | Sartorius Gmbh | Anzeige- und Bedieneinheit für eine Waage |
DE10010073B4 (de) | 2000-02-28 | 2005-12-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verankerung für implantierbare Herzklappenprothesen |
EP1261282B1 (de) | 2000-03-03 | 2013-09-25 | C. R. Bard, Inc. | Endoskopisches gewebeappositionsgerät mit mehreren absaugöffnungen |
EP1261294B1 (de) | 2000-03-10 | 2006-11-29 | Paracor Medical, Inc. | Expandierbarer herzbeutel zur behandlung von kongestiven herzversagens |
US6537198B1 (en) * | 2000-03-21 | 2003-03-25 | Myocor, Inc. | Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly |
US6454799B1 (en) | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
US6610088B1 (en) | 2000-05-03 | 2003-08-26 | Shlomo Gabbay | Biologically covered heart valve prosthesis |
US6951534B2 (en) | 2000-06-13 | 2005-10-04 | Acorn Cardiovascular, Inc. | Cardiac support device |
US6358277B1 (en) | 2000-06-21 | 2002-03-19 | The International Heart Institute Of Montana Foundation | Atrio-ventricular valvular device |
GB2365881A (en) | 2000-07-06 | 2002-02-27 | David Paul Aviram | Interlocking structural panel set |
US20050113798A1 (en) | 2000-07-21 | 2005-05-26 | Slater Charles R. | Methods and apparatus for treating the interior of a blood vessel |
WO2002022054A1 (en) | 2000-09-12 | 2002-03-21 | Gabbay S | Valvular prosthesis and method of using same |
US7510572B2 (en) * | 2000-09-12 | 2009-03-31 | Shlomo Gabbay | Implantation system for delivery of a heart valve prosthesis |
US8956407B2 (en) | 2000-09-20 | 2015-02-17 | Mvrx, Inc. | Methods for reshaping a heart valve annulus using a tensioning implant |
US20080091264A1 (en) | 2002-11-26 | 2008-04-17 | Ample Medical, Inc. | Devices, systems, and methods for reshaping a heart valve annulus, including the use of magnetic tools |
US6461382B1 (en) | 2000-09-22 | 2002-10-08 | Edwards Lifesciences Corporation | Flexible heart valve having moveable commissures |
US6602288B1 (en) | 2000-10-05 | 2003-08-05 | Edwards Lifesciences Corporation | Minimally-invasive annuloplasty repair segment delivery template, system and method of use |
US6723038B1 (en) | 2000-10-06 | 2004-04-20 | Myocor, Inc. | Methods and devices for improving mitral valve function |
US6616684B1 (en) | 2000-10-06 | 2003-09-09 | Myocor, Inc. | Endovascular splinting devices and methods |
DE10049813C1 (de) | 2000-10-09 | 2002-04-18 | Universitaetsklinikum Freiburg | Vorrichtung zum lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz |
DE10049815B4 (de) | 2000-10-09 | 2005-10-13 | Universitätsklinikum Freiburg | Vorrichtung zum lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz |
DE10049814B4 (de) | 2000-10-09 | 2006-10-19 | Universitätsklinikum Freiburg | Vorrichtung zur Unterstützung chirurgischer Maßnahmen innerhalb eines Gefäßes, insbesondere zur minimalinvasiven Explantation und Implantation von Herzklappen |
DE10049812B4 (de) | 2000-10-09 | 2004-06-03 | Universitätsklinikum Freiburg | Vorrichtung zum Ausfiltern makroskopischer Teilchen aus der Blutbahn beim lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz |
WO2002038051A2 (en) | 2000-11-07 | 2002-05-16 | Carag Ag | A device for plugging an opening such as in a wall of a hollow or tubular organ |
US6482228B1 (en) | 2000-11-14 | 2002-11-19 | Troy R. Norred | Percutaneous aortic valve replacement |
DE60112603T2 (de) | 2000-11-21 | 2006-06-14 | Rex Medical Lp | Perkutane aortenklappe |
US6974476B2 (en) | 2003-05-05 | 2005-12-13 | Rex Medical, L.P. | Percutaneous aortic valve |
US6976543B1 (en) | 2000-11-22 | 2005-12-20 | Grinnell Corporation | Low pressure, extended coverage, upright fire protection sprinkler |
US6494909B2 (en) | 2000-12-01 | 2002-12-17 | Prodesco, Inc. | Endovascular valve |
US20040093075A1 (en) | 2000-12-15 | 2004-05-13 | Titus Kuehne | Stent with valve and method of use thereof |
US6468660B2 (en) | 2000-12-29 | 2002-10-22 | St. Jude Medical, Inc. | Biocompatible adhesives |
US6810882B2 (en) | 2001-01-30 | 2004-11-02 | Ev3 Santa Rosa, Inc. | Transluminal mitral annuloplasty |
NL1017275C2 (nl) | 2001-02-02 | 2002-08-05 | Univ Eindhoven Tech | Hartklep. |
US8038708B2 (en) | 2001-02-05 | 2011-10-18 | Cook Medical Technologies Llc | Implantable device with remodelable material and covering material |
US7326564B2 (en) | 2001-02-20 | 2008-02-05 | St. Jude Medical, Inc. | Flow system for medical device evaluation and production |
US20020139056A1 (en) | 2001-03-05 | 2002-10-03 | Finnell Lee M. | Fire protection system |
US6488704B1 (en) | 2001-05-07 | 2002-12-03 | Biomed Solutions, Llc | Implantable particle measuring apparatus |
CA2441886C (en) | 2001-03-23 | 2009-07-21 | Viacor, Incorporated | Method and apparatus for reducing mitral regurgitation |
US7556646B2 (en) | 2001-09-13 | 2009-07-07 | Edwards Lifesciences Corporation | Methods and apparatuses for deploying minimally-invasive heart valves |
US7374571B2 (en) * | 2001-03-23 | 2008-05-20 | Edwards Lifesciences Corporation | Rolled minimally-invasive heart valves and methods of manufacture |
US6733525B2 (en) | 2001-03-23 | 2004-05-11 | Edwards Lifesciences Corporation | Rolled minimally-invasive heart valves and methods of use |
US6622730B2 (en) | 2001-03-30 | 2003-09-23 | Myocor, Inc. | Device for marking and aligning positions on the heart |
US20050113810A1 (en) * | 2001-04-24 | 2005-05-26 | Houser Russell A. | Shaping suture for treating congestive heart failure |
US20050113811A1 (en) * | 2001-04-24 | 2005-05-26 | Houser Russell A. | Method and devices for treating ischemic congestive heart failure |
US20050096498A1 (en) * | 2001-04-24 | 2005-05-05 | Houser Russell A. | Sizing and shaping device for treating congestive heart failure |
US6837901B2 (en) | 2001-04-27 | 2005-01-04 | Intek Technology L.L.C. | Methods for delivering, repositioning and/or retrieving self-expanding stents |
US20020188170A1 (en) | 2001-04-27 | 2002-12-12 | Santamore William P. | Prevention of myocardial infarction induced ventricular expansion and remodeling |
GB0110551D0 (en) | 2001-04-30 | 2001-06-20 | Angiomed Ag | Self-expanding stent delivery service |
ITMI20011012A1 (it) | 2001-05-17 | 2002-11-17 | Ottavio Alfieri | Protesi anulare per valvola mitrale |
US6936067B2 (en) | 2001-05-17 | 2005-08-30 | St. Jude Medical Inc. | Prosthetic heart valve with slit stent |
US6575252B2 (en) | 2001-05-29 | 2003-06-10 | Jeffrey Paul Reed | Sprinkler head deactivating tool |
US20040064014A1 (en) * | 2001-05-31 | 2004-04-01 | Melvin David B. | Devices and methods for assisting natural heart function |
US6926732B2 (en) | 2001-06-01 | 2005-08-09 | Ams Research Corporation | Stent delivery device and method |
KR100393548B1 (ko) | 2001-06-05 | 2003-08-02 | 주식회사 엠아이텍 | 의료용 스텐트 |
FR2826863B1 (fr) | 2001-07-04 | 2003-09-26 | Jacques Seguin | Ensemble permettant la mise en place d'une valve prothetique dans un conduit corporel |
US6648077B2 (en) * | 2001-07-12 | 2003-11-18 | Bryan K. Hoffman | Fire extinguishing system |
FR2828263B1 (fr) | 2001-08-03 | 2007-05-11 | Philipp Bonhoeffer | Dispositif d'implantation d'un implant et procede d'implantation du dispositif |
US20030036698A1 (en) | 2001-08-16 | 2003-02-20 | Robert Kohler | Interventional diagnostic catheter and a method for using a catheter to access artificial cardiac shunts |
US6648921B2 (en) | 2001-10-03 | 2003-11-18 | Ams Research Corporation | Implantable article |
US6893460B2 (en) * | 2001-10-11 | 2005-05-17 | Percutaneous Valve Technologies Inc. | Implantable prosthetic valve |
US7143834B2 (en) * | 2001-11-01 | 2006-12-05 | Kevin Michael Dolan | Sprinkler assembly |
WO2003043676A2 (en) * | 2001-11-23 | 2003-05-30 | Mindguard Ltd. | Expandable delivery appliance particularly for delivering intravascular devices |
US20050177180A1 (en) | 2001-11-28 | 2005-08-11 | Aptus Endosystems, Inc. | Devices, systems, and methods for supporting tissue and/or structures within a hollow body organ |
US7182779B2 (en) | 2001-12-03 | 2007-02-27 | Xtent, Inc. | Apparatus and methods for positioning prostheses for deployment from a catheter |
US6793673B2 (en) * | 2002-12-26 | 2004-09-21 | Cardiac Dimensions, Inc. | System and method to effect mitral valve annulus of a heart |
US6908478B2 (en) | 2001-12-05 | 2005-06-21 | Cardiac Dimensions, Inc. | Anchor and pull mitral valve device and method |
US7094246B2 (en) | 2001-12-07 | 2006-08-22 | Abbott Laboratories | Suture trimmer |
US6978176B2 (en) * | 2001-12-08 | 2005-12-20 | Lattouf Omar M | Treatment for patient with congestive heart failure |
US20030120340A1 (en) | 2001-12-26 | 2003-06-26 | Jan Liska | Mitral and tricuspid valve repair |
US6764510B2 (en) | 2002-01-09 | 2004-07-20 | Myocor, Inc. | Devices and methods for heart valve treatment |
US6854668B2 (en) | 2002-04-29 | 2005-02-15 | Victaulic Company Of America | Extended coverage ordinary hazard sprinkler system |
US6746401B2 (en) | 2002-05-06 | 2004-06-08 | Scimed Life Systems, Inc. | Tissue ablation visualization |
US7141064B2 (en) | 2002-05-08 | 2006-11-28 | Edwards Lifesciences Corporation | Compressed tissue for heart valve leaflets |
EP1521550A4 (de) | 2002-06-12 | 2011-02-23 | Mitral Interventions Inc | Verfahren und vorrichtung für eine gewebeverbindung |
US7753924B2 (en) | 2003-09-04 | 2010-07-13 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
WO2004002364A2 (en) * | 2002-06-27 | 2004-01-08 | Levine Robert A | Ventricular remodeling for artioventricular valve regurgitation |
US20050125012A1 (en) * | 2002-06-28 | 2005-06-09 | Houser Russell A. | Hemostatic patch for treating congestive heart failure |
EP1592367B1 (de) * | 2002-08-28 | 2016-04-13 | HLT, Inc. | Verfahren und vorrichtung zur behandlung erkrankter klappen |
US6875231B2 (en) | 2002-09-11 | 2005-04-05 | 3F Therapeutics, Inc. | Percutaneously deliverable heart valve |
US7137184B2 (en) | 2002-09-20 | 2006-11-21 | Edwards Lifesciences Corporation | Continuous heart valve support frame and method of manufacture |
WO2004032796A2 (en) | 2002-10-10 | 2004-04-22 | The Cleveland Clinic Foundation | Method and apparatus for replacing a mitral valve with a stentless bioprosthetic valve |
US7087064B1 (en) | 2002-10-15 | 2006-08-08 | Advanced Cardiovascular Systems, Inc. | Apparatuses and methods for heart valve repair |
US7025285B2 (en) | 2002-10-22 | 2006-04-11 | University Of Florida Research Foundation, Inc. | Fire sprinkler flow control device |
US7247134B2 (en) | 2002-11-12 | 2007-07-24 | Myocor, Inc. | Devices and methods for heart valve treatment |
US7112219B2 (en) | 2002-11-12 | 2006-09-26 | Myocor, Inc. | Devices and methods for heart valve treatment |
US7404824B1 (en) * | 2002-11-15 | 2008-07-29 | Advanced Cardiovascular Systems, Inc. | Valve aptation assist device |
US7335213B1 (en) | 2002-11-15 | 2008-02-26 | Abbott Cardiovascular Systems Inc. | Apparatus and methods for heart valve repair |
US6997950B2 (en) | 2003-01-16 | 2006-02-14 | Chawla Surendra K | Valve repair device |
US8157810B2 (en) | 2003-02-26 | 2012-04-17 | Cook Medical Technologies Llc | Prosthesis adapted for placement under external imaging |
US7381210B2 (en) | 2003-03-14 | 2008-06-03 | Edwards Lifesciences Corporation | Mitral valve repair system and method for use |
EP1608297A2 (de) | 2003-03-18 | 2005-12-28 | St. Jude Medical, Inc. | Gerät zur remodellierung von körpergewebe |
US7175656B2 (en) | 2003-04-18 | 2007-02-13 | Alexander Khairkhahan | Percutaneous transcatheter heart valve replacement |
US6945996B2 (en) | 2003-04-18 | 2005-09-20 | Sedransk Kyra L | Replacement mitral valve |
ATE446061T1 (de) | 2003-04-24 | 2009-11-15 | Cook Inc | Künstliche klappe für blutgefäss mit verbessertem fliessverhalten |
US7625399B2 (en) | 2003-04-24 | 2009-12-01 | Cook Incorporated | Intralumenally-implantable frames |
EP1635736A2 (de) | 2003-06-05 | 2006-03-22 | FlowMedica, Inc. | Systeme und verfahren zur durchführung von bilateralen interventionen oder diagnose in verzweigten körperlumen |
US7316706B2 (en) * | 2003-06-20 | 2008-01-08 | Medtronic Vascular, Inc. | Tensioning device, system, and method for treating mitral valve regurgitation |
EP1648346A4 (de) | 2003-06-20 | 2006-10-18 | Medtronic Vascular Inc | Klappenöffnungsreduktionssystem |
WO2005002424A2 (en) | 2003-07-02 | 2005-01-13 | Flexcor, Inc. | Annuloplasty rings and methods for repairing cardiac valves |
US7201772B2 (en) | 2003-07-08 | 2007-04-10 | Ventor Technologies, Ltd. | Fluid flow prosthetic device |
RU2006103367A (ru) | 2003-07-08 | 2006-06-27 | Вентор Текнолоджиз Лтд. (Il) | Имплантируемые протезные устройства, в частности, для трансартериальной доставки при лечении аортального стеноза и способы имплантации таких устройств |
US7513867B2 (en) | 2003-07-16 | 2009-04-07 | Kardium, Inc. | Methods and devices for altering blood flow through the left ventricle |
EP1653888B1 (de) | 2003-07-21 | 2009-09-09 | The Trustees of The University of Pennsylvania | Perkutane herzklappe |
WO2005011535A2 (en) | 2003-07-31 | 2005-02-10 | Cook Incorporated | Prosthetic valve for implantation in a body vessel |
US20060259137A1 (en) | 2003-10-06 | 2006-11-16 | Jason Artof | Minimally invasive valve replacement system |
US10219899B2 (en) * | 2004-04-23 | 2019-03-05 | Medtronic 3F Therapeutics, Inc. | Cardiac valve replacement systems |
US7326236B2 (en) | 2003-12-23 | 2008-02-05 | Xtent, Inc. | Devices and methods for controlling and indicating the length of an interventional element |
US8182528B2 (en) | 2003-12-23 | 2012-05-22 | Sadra Medical, Inc. | Locking heart valve anchor |
US7959666B2 (en) | 2003-12-23 | 2011-06-14 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US20050137686A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Externally expandable heart valve anchor and method |
US7748389B2 (en) | 2003-12-23 | 2010-07-06 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US7780725B2 (en) | 2004-06-16 | 2010-08-24 | Sadra Medical, Inc. | Everting heart valve |
US8840663B2 (en) * | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
US8052749B2 (en) | 2003-12-23 | 2011-11-08 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US7445631B2 (en) | 2003-12-23 | 2008-11-04 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
CA2556077C (en) | 2004-02-05 | 2012-05-01 | Children's Medical Center Corporation | Transcatheter delivery of a replacement heart valve |
US8206439B2 (en) | 2004-02-23 | 2012-06-26 | International Heart Institute Of Montana Foundation | Internal prosthesis for reconstruction of cardiac geometry |
US8430925B2 (en) | 2004-02-27 | 2013-04-30 | Cardiacmd, Inc. | Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same |
US20070073387A1 (en) * | 2004-02-27 | 2007-03-29 | Forster David C | Prosthetic Heart Valves, Support Structures And Systems And Methods For Implanting The Same |
US20090132035A1 (en) * | 2004-02-27 | 2009-05-21 | Roth Alex T | Prosthetic Heart Valves, Support Structures and Systems and Methods for Implanting the Same |
ITTO20040135A1 (it) * | 2004-03-03 | 2004-06-03 | Sorin Biomedica Cardio Spa | Protesi valvolare cardiaca |
EP1734903B2 (de) | 2004-03-11 | 2022-01-19 | Percutaneous Cardiovascular Solutions Pty Limited | Perkutane herzklappenprothese |
NL1025830C2 (nl) | 2004-03-26 | 2005-02-22 | Eric Berreklouw | Samenstel omvattende een ring voor bevestiging in een door lichaamsweefsel omgeven doorgang alsmede een applicator voor het in de doorgang plaatsen van de ring. |
US20060004323A1 (en) | 2004-04-21 | 2006-01-05 | Exploramed Nc1, Inc. | Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures |
JP5290573B2 (ja) * | 2004-04-23 | 2013-09-18 | メドトロニック スリーエフ セラピューティクス,インコーポレイティド | 移植可能な補綴具弁 |
JP5227588B2 (ja) | 2004-05-05 | 2013-07-03 | ダイレクト フロウ メディカル、 インク. | 現場形成支持構造を備えたステントレス心臓弁 |
US8257394B2 (en) | 2004-05-07 | 2012-09-04 | Usgi Medical, Inc. | Apparatus and methods for positioning and securing anchors |
US7938856B2 (en) | 2004-05-14 | 2011-05-10 | St. Jude Medical, Inc. | Heart valve annuloplasty prosthesis sewing cuffs and methods of making same |
US20050288766A1 (en) | 2004-06-28 | 2005-12-29 | Xtent, Inc. | Devices and methods for controlling expandable prostheses during deployment |
US20050288777A1 (en) | 2004-06-29 | 2005-12-29 | Rhee Richard S | Thermal conductor for adjustable cardiac valve implant |
US7462191B2 (en) | 2004-06-30 | 2008-12-09 | Edwards Lifesciences Pvt, Inc. | Device and method for assisting in the implantation of a prosthetic valve |
US7276078B2 (en) | 2004-06-30 | 2007-10-02 | Edwards Lifesciences Pvt | Paravalvular leak detection, sealing, and prevention |
EP1781179A1 (de) | 2004-07-06 | 2007-05-09 | Baker Medical Research Institute | Behandlung von klappeninsuffizienz |
US20060042803A1 (en) * | 2004-08-31 | 2006-03-02 | Jeanette M. Gallaher | Sprinkler head shut-off tool |
US7566343B2 (en) | 2004-09-02 | 2009-07-28 | Boston Scientific Scimed, Inc. | Cardiac valve, system, and method |
US20060052867A1 (en) | 2004-09-07 | 2006-03-09 | Medtronic, Inc | Replacement prosthetic heart valve, system and method of implant |
US20070162100A1 (en) | 2006-01-10 | 2007-07-12 | Shlomo Gabbay | System and method for loading implanter with prosthesis |
WO2006055982A2 (en) | 2004-11-22 | 2006-05-26 | Avvrx | Ring-shaped valve prosthesis attachment device |
KR101300640B1 (ko) | 2004-11-29 | 2013-08-28 | 피닉스 화이어화이팅 테크놀로지스 에스에이 | 밸브들을 구비한 소방 시스템에 적합한 시스템 |
CN101076290B (zh) | 2004-12-09 | 2011-11-23 | 铸造品股份有限公司 | 主动脉瓣修复 |
US7211110B2 (en) | 2004-12-09 | 2007-05-01 | Edwards Lifesciences Corporation | Diagnostic kit to assist with heart valve annulus adjustment |
IE20050841A1 (en) | 2004-12-15 | 2006-10-04 | Mednua Ltd | A medical device suitable for use in treatment of a valve |
US20060142784A1 (en) | 2004-12-28 | 2006-06-29 | Stavros Kontos | Device and method for suturing internal structures puncture wounds |
DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
EP1841368B1 (de) | 2005-01-25 | 2015-06-10 | Covidien LP | Strukturen für den dauerhaften verschluss einer hohlen anatomischen struktur |
WO2006086434A1 (en) | 2005-02-07 | 2006-08-17 | Evalve, Inc. | Methods, systems and devices for cardiac valve repair |
WO2011034628A1 (en) | 2005-02-07 | 2011-03-24 | Evalve, Inc. | Methods, systems and devices for cardiac valve repair |
DE102005007341B4 (de) * | 2005-02-17 | 2007-10-11 | Kasprzak, Piotr, Dr. | Stentprothese für die Gefäßchirurgie insbesondere im Bereich des Aortenbogens |
US8685086B2 (en) | 2006-02-18 | 2014-04-01 | The Cleveland Clinic Foundation | Apparatus and method for replacing a diseased cardiac valve |
US20060195183A1 (en) | 2005-02-18 | 2006-08-31 | The Cleveland Clinic Foundation | Apparatus and methods for replacing a cardiac valve |
US7331991B2 (en) | 2005-02-25 | 2008-02-19 | California Institute Of Technology | Implantable small percutaneous valve and methods of delivery |
US7717955B2 (en) | 2005-02-28 | 2010-05-18 | Medtronic, Inc. | Conformable prosthesis for implanting two-piece heart valves and methods for using them |
US7955385B2 (en) * | 2005-02-28 | 2011-06-07 | Medtronic Vascular, Inc. | Device, system, and method for aiding valve annuloplasty |
WO2006105008A1 (en) | 2005-03-25 | 2006-10-05 | Ample Medical, Inc. | Device, systems, and methods for reshaping a heart valve annulus |
US7579381B2 (en) | 2005-03-25 | 2009-08-25 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
US8062359B2 (en) | 2005-04-06 | 2011-11-22 | Edwards Lifesciences Corporation | Highly flexible heart valve connecting band |
WO2006113906A1 (en) | 2005-04-20 | 2006-10-26 | The Cleveland Clinic Foundation | Apparatus and method for replacing a cardiac valve |
SE531468C2 (sv) | 2005-04-21 | 2009-04-14 | Edwards Lifesciences Ag | En anordning för styrning av blodflöde |
US8333777B2 (en) | 2005-04-22 | 2012-12-18 | Benvenue Medical, Inc. | Catheter-based tissue remodeling devices and methods |
US20060247491A1 (en) | 2005-04-27 | 2006-11-02 | Vidlund Robert M | Devices and methods for heart valve treatment |
US7914569B2 (en) | 2005-05-13 | 2011-03-29 | Medtronics Corevalve Llc | Heart valve prosthesis and methods of manufacture and use |
US7854762B2 (en) | 2005-05-20 | 2010-12-21 | Mayo Foundation For Medical Education And Research | Devices and methods for reducing cardiac valve regurgitation |
WO2006127756A2 (en) | 2005-05-24 | 2006-11-30 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
US8663312B2 (en) | 2005-05-27 | 2014-03-04 | Hlt, Inc. | Intravascular cuff |
US7500989B2 (en) | 2005-06-03 | 2009-03-10 | Edwards Lifesciences Corp. | Devices and methods for percutaneous repair of the mitral valve via the coronary sinus |
US20060287716A1 (en) | 2005-06-08 | 2006-12-21 | The Cleveland Clinic Foundation | Artificial chordae |
US20090082619A1 (en) * | 2005-06-09 | 2009-03-26 | De Marchena Eduardo | Method of treating cardiomyopathy |
JP4987861B2 (ja) * | 2005-06-09 | 2012-07-25 | ザユニバーシティー オブ マイアミ | 左心室縮小のための乳頭筋装着具 |
US7780723B2 (en) | 2005-06-13 | 2010-08-24 | Edwards Lifesciences Corporation | Heart valve delivery system |
US20080058856A1 (en) | 2005-06-28 | 2008-03-06 | Venkatesh Ramaiah | Non-occluding dilation device |
JP2007011557A (ja) | 2005-06-29 | 2007-01-18 | Nissan Motor Co Ltd | 渋滞検出システム、車載情報端末、および情報センター、および渋滞検出方法 |
US7931630B2 (en) | 2005-07-05 | 2011-04-26 | C. R. Bard, Inc. | Multi-functional and modular urine collection system |
US20070162111A1 (en) * | 2005-07-06 | 2007-07-12 | The Cleveland Clinic Foundation | Apparatus and method for replacing a cardiac valve |
US20070016288A1 (en) | 2005-07-13 | 2007-01-18 | Gurskis Donnell W | Two-piece percutaneous prosthetic heart valves and methods for making and using them |
US7927371B2 (en) | 2005-07-15 | 2011-04-19 | The Cleveland Clinic Foundation | Apparatus and method for reducing cardiac valve regurgitation |
US20090112309A1 (en) * | 2005-07-21 | 2009-04-30 | The Florida International University Board Of Trustees | Collapsible Heart Valve with Polymer Leaflets |
WO2007016251A2 (en) | 2005-07-28 | 2007-02-08 | Cook Incorporated | Implantable thromboresistant valve |
EP1933756B1 (de) | 2005-08-19 | 2016-07-20 | CHF Technologies Inc. | Lenkbare läsionsausschliessende herzimplantate bei kongestiver herzinsuffizienz |
US20070078297A1 (en) * | 2005-08-31 | 2007-04-05 | Medtronic Vascular, Inc. | Device for Treating Mitral Valve Regurgitation |
US7632304B2 (en) | 2005-09-07 | 2009-12-15 | Rbkpark Llc | Coronary stent |
US20070061010A1 (en) | 2005-09-09 | 2007-03-15 | Hauser David L | Device and method for reshaping mitral valve annulus |
US20080188928A1 (en) | 2005-09-16 | 2008-08-07 | Amr Salahieh | Medical device delivery sheath |
US7695510B2 (en) | 2005-10-11 | 2010-04-13 | Medtronic Vascular, Inc. | Annuloplasty device having shape-adjusting tension filaments |
US7275604B1 (en) | 2005-10-12 | 2007-10-02 | Wall Terry M | Multi-zone firewall detection system |
US8167932B2 (en) | 2005-10-18 | 2012-05-01 | Edwards Lifesciences Corporation | Heart valve delivery system with valve catheter |
US9259317B2 (en) | 2008-06-13 | 2016-02-16 | Cardiosolutions, Inc. | System and method for implanting a heart implant |
US8092525B2 (en) | 2005-10-26 | 2012-01-10 | Cardiosolutions, Inc. | Heart valve implant |
US8216302B2 (en) | 2005-10-26 | 2012-07-10 | Cardiosolutions, Inc. | Implant delivery and deployment system and method |
US7785366B2 (en) | 2005-10-26 | 2010-08-31 | Maurer Christopher W | Mitral spacer |
US20070100439A1 (en) * | 2005-10-31 | 2007-05-03 | Medtronic Vascular, Inc. | Chordae tendinae restraining ring |
DE102005052628B4 (de) | 2005-11-04 | 2014-06-05 | Jenavalve Technology Inc. | Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter |
CN100584292C (zh) | 2005-11-09 | 2010-01-27 | 温宁 | 人工心脏支架瓣膜 |
CN2902226Y (zh) | 2005-11-09 | 2007-05-23 | 王蓉珍 | 人工心脏支架瓣膜 |
US8764820B2 (en) | 2005-11-16 | 2014-07-01 | Edwards Lifesciences Corporation | Transapical heart valve delivery system and method |
US20070118210A1 (en) | 2005-11-18 | 2007-05-24 | Leonard Pinchuk | Trileaflet Heart Valve |
WO2007062054A2 (en) * | 2005-11-21 | 2007-05-31 | The Brigham And Women's Hospital, Inc. | Percutaneous cardiac valve repair with adjustable artificial chordae |
US7632308B2 (en) | 2005-11-23 | 2009-12-15 | Didier Loulmet | Methods, devices, and kits for treating mitral valve prolapse |
US8043368B2 (en) | 2005-11-23 | 2011-10-25 | Traves Dean Crabtree | Methods and apparatus for atrioventricular valve repair |
US9034006B2 (en) | 2005-12-01 | 2015-05-19 | Atritech, Inc. | Method and apparatus for retrieving an embolized implant |
CA2669188C (en) | 2005-12-15 | 2014-08-05 | Georgia Tech Research Corporation | Papillary muscle position control devices, systems, & methods |
EP1959865B1 (de) | 2005-12-15 | 2014-12-10 | The Cleveland Clinic Foundation | Gerät zur behandlung von klappen-regurgitation |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
WO2007130724A2 (en) | 2006-02-06 | 2007-11-15 | Northwind Ventures | Systems and methods for volume reduction |
US20070185571A1 (en) | 2006-02-06 | 2007-08-09 | The Cleveland Clinic Foundation | Apparatus and method for treating a regurgitant valve |
WO2008029296A2 (en) | 2006-02-16 | 2008-03-13 | Endocor Pte Ltd. | Minimally invasive heart valve replacement |
US8147541B2 (en) | 2006-02-27 | 2012-04-03 | Aortx, Inc. | Methods and devices for delivery of prosthetic heart valves and other prosthetics |
US7635386B1 (en) | 2006-03-07 | 2009-12-22 | University Of Maryland, Baltimore | Methods and devices for performing cardiac valve repair |
GB0604952D0 (en) | 2006-03-13 | 2006-04-19 | Renishaw Plc | A fluid connector for fluid delivery apparatus |
US20070215362A1 (en) | 2006-03-20 | 2007-09-20 | Fire Sprinkler System, Inc. | Fire sprinkler system |
CA2646078C (en) | 2006-03-22 | 2014-12-16 | Lubrizol Advanced Materials, Inc. | Fire suppression system |
US20110224678A1 (en) | 2006-03-23 | 2011-09-15 | Shlomo Gabbay | Method and implantation system for implanting a cardiovascular prosthesis |
US7524331B2 (en) | 2006-04-06 | 2009-04-28 | Medtronic Vascular, Inc. | Catheter delivered valve having a barrier to provide an enhanced seal |
EP2023860A2 (de) | 2006-04-29 | 2009-02-18 | Arbor Surgical Technologies, Inc. | Mehrteilige herzklappenprothesenanordnungen sowie vorrichtung und verfahren zu ihrer einsetzung |
US7343980B2 (en) | 2006-05-04 | 2008-03-18 | The Reliable Automatic Sprinkler Co., Inc. | Enhanced protection extended coverage pendent fire protection sprinkler |
US20070265658A1 (en) | 2006-05-12 | 2007-11-15 | Aga Medical Corporation | Anchoring and tethering system |
ATE499074T1 (de) | 2006-05-15 | 2011-03-15 | Edwards Lifesciences Ag | System zur veränderung der geometrie des herzens |
US8932348B2 (en) | 2006-05-18 | 2015-01-13 | Edwards Lifesciences Corporation | Device and method for improving heart valve function |
US8535368B2 (en) | 2006-05-19 | 2013-09-17 | Boston Scientific Scimed, Inc. | Apparatus for loading and delivering a stent |
EP2034929A4 (de) | 2006-06-20 | 2010-04-07 | Aortx Inc | Herzklappenprothese, trägerstrukturen sowie systeme und verfahren zur prothesenimplantierung |
GB0614445D0 (en) | 2006-07-20 | 2006-08-30 | Ricardo Uk Ltd | Control of selective catalytic reduction |
WO2008031103A2 (en) | 2006-09-08 | 2008-03-13 | Edwards Lifesciences Corporation | Integrated heart valve delivery system |
US8876895B2 (en) | 2006-09-19 | 2014-11-04 | Medtronic Ventor Technologies Ltd. | Valve fixation member having engagement arms |
FR2906454B1 (fr) * | 2006-09-28 | 2009-04-10 | Perouse Soc Par Actions Simpli | Implant destine a etre place dans un conduit de circulation du sang. |
US7578842B2 (en) | 2006-10-03 | 2009-08-25 | St. Jude Medical, Inc. | Prosthetic heart valves |
US8029556B2 (en) | 2006-10-04 | 2011-10-04 | Edwards Lifesciences Corporation | Method and apparatus for reshaping a ventricle |
US7422072B2 (en) | 2006-10-06 | 2008-09-09 | Kent Demond Dade | Sprinkler wedge |
US8388680B2 (en) | 2006-10-18 | 2013-03-05 | Guided Delivery Systems, Inc. | Methods and devices for catheter advancement and delivery of substances therethrough |
CN101626682B (zh) | 2006-10-27 | 2014-04-16 | 爱德华兹生命科学公司 | 用于外科植入的生物组织 |
DE102006052564B3 (de) | 2006-11-06 | 2007-12-13 | Georg Lutter | Mitralklappenstent |
US8460372B2 (en) | 2006-11-07 | 2013-06-11 | Dc Devices, Inc. | Prosthesis for reducing intra-cardiac pressure having an embolic filter |
EP3329860A1 (de) | 2006-11-07 | 2018-06-06 | David Stephen Celermajer | Vorrichtungen zur behandlung von herzversagen |
DE102006052710A1 (de) | 2006-11-08 | 2008-05-29 | Siemens Ag | Vorrichtung zur Untersuchung und zur Durchführung von Interventionen, Punktionen und Injektionen |
US8052732B2 (en) | 2006-11-14 | 2011-11-08 | Medtronic Vascular, Inc. | Delivery system for stent-graft with anchoring pins |
EP2954876B1 (de) | 2006-12-19 | 2018-12-19 | St. Jude Medical, Inc. | Verfahren zur herstellung einer herzklappenprothese mit stentstruktur und gewebeblättchen |
US8236045B2 (en) | 2006-12-22 | 2012-08-07 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method of making the same |
MX2009007289A (es) | 2007-01-03 | 2009-09-09 | Mitralsolutions Inc | Dispositivos implantables para controlar el tamaño y la forma de una estructura o lumen anatomico. |
US9510943B2 (en) | 2007-01-19 | 2016-12-06 | Medtronic, Inc. | Stented heart valve devices and methods for atrioventricular valve replacement |
WO2008089365A2 (en) | 2007-01-19 | 2008-07-24 | The Cleveland Clinic Foundation | Method for implanting a cardiovascular valve |
WO2008091991A2 (en) | 2007-01-25 | 2008-07-31 | Trinity Health-Michigan | Blood vessel occluder and method of use |
WO2008097589A1 (en) | 2007-02-05 | 2008-08-14 | Boston Scientific Limited | Percutaneous valve, system, and method |
WO2009024859A2 (en) | 2007-08-21 | 2009-02-26 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
EP3345572A1 (de) | 2007-02-14 | 2018-07-11 | Edwards Lifesciences Corporation | Naht und verfahren zur herzreparatur |
CA2677633C (en) | 2007-02-15 | 2015-09-08 | Medtronic, Inc. | Multi-layered stents and methods of implanting |
US8070802B2 (en) | 2007-02-23 | 2011-12-06 | The Trustees Of The University Of Pennsylvania | Mitral valve system |
US7753949B2 (en) | 2007-02-23 | 2010-07-13 | The Trustees Of The University Of Pennsylvania | Valve prosthesis systems and methods |
WO2008121888A1 (en) | 2007-03-30 | 2008-10-09 | Onset Medical Corporation | Expandable trans-septal sheath |
US7896915B2 (en) * | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US9138315B2 (en) | 2007-04-13 | 2015-09-22 | Jenavalve Technology Gmbh | Medical device for treating a heart valve insufficiency or stenosis |
US8480730B2 (en) | 2007-05-14 | 2013-07-09 | Cardiosolutions, Inc. | Solid construct mitral spacer |
EP2659861B1 (de) | 2007-05-15 | 2019-03-13 | JenaValve Technology, Inc. | Griff zur Manipulation einer Katheterspitze, Kathetersystem und medizinisches Einführsystem zum Einführen eines selbstexpandierbaren Herzklappenstents |
US20080294248A1 (en) | 2007-05-25 | 2008-11-27 | Medical Entrepreneurs Ii, Inc. | Prosthetic Heart Valve |
JP5367700B2 (ja) | 2007-06-04 | 2013-12-11 | セント ジュード メディカル インコーポレイテッド | 人工心臓弁 |
US8512398B2 (en) | 2007-06-26 | 2013-08-20 | St. Jude Medical, Inc. | Apparatus and method for implanting collapsible/expandable prosthetic heart valves |
CN101970232A (zh) | 2007-07-23 | 2011-02-09 | 大道产业株式会社 | 印刷物干燥方法及印刷物干燥装置 |
EP2173275B1 (de) * | 2007-07-30 | 2022-03-02 | Boston Scientific Scimed, Inc. | Vorrichtung zur behandlung von belastungsinkontinenz |
US20090216322A1 (en) | 2007-08-10 | 2009-08-27 | Le Le | Adjustable annuloplasty ring and activation system |
WO2009026272A1 (en) | 2007-08-21 | 2009-02-26 | Valvexchange Inc. | Method and apparatus for prosthetic valve removal |
CA2978267A1 (en) | 2007-08-23 | 2009-02-23 | Dfm, Llc | Translumenally implantable heart valve with formed in place support |
BRPI0815751A2 (pt) | 2007-08-24 | 2015-02-18 | St Jude Medical | Válvula aórtica protética. |
DE102007043830A1 (de) | 2007-09-13 | 2009-04-02 | Lozonschi, Lucian, Madison | Herzklappenstent |
DE102007043831B4 (de) | 2007-09-13 | 2009-07-02 | Lozonschi, Lucian, Madison | Katheter |
EP2190385B8 (de) | 2007-09-26 | 2017-06-07 | St. Jude Medical, LLC | Faltbare herzklappenprothesen |
WO2009045334A1 (en) | 2007-09-28 | 2009-04-09 | St. Jude Medical, Inc. | Collapsible/expandable prosthetic heart valves with native calcified leaflet retention features |
US9532868B2 (en) | 2007-09-28 | 2017-01-03 | St. Jude Medical, Inc. | Collapsible-expandable prosthetic heart valves with structures for clamping native tissue |
US20090138079A1 (en) * | 2007-10-10 | 2009-05-28 | Vector Technologies Ltd. | Prosthetic heart valve for transfemoral delivery |
US8043301B2 (en) | 2007-10-12 | 2011-10-25 | Spiration, Inc. | Valve loader method, system, and apparatus |
CA2702615C (en) | 2007-10-19 | 2017-06-06 | Guided Delivery Systems, Inc. | Systems and methods for cardiac remodeling |
US8597347B2 (en) | 2007-11-15 | 2013-12-03 | Cardiosolutions, Inc. | Heart regurgitation method and apparatus |
DK3646822T3 (da) | 2007-12-14 | 2021-09-06 | Edwards Lifesciences Corp | Bladfastgørelsesramme til en proteseklap |
US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
US20090171456A1 (en) | 2007-12-28 | 2009-07-02 | Kveen Graig L | Percutaneous heart valve, system, and method |
EP2240121B1 (de) | 2008-01-16 | 2019-05-22 | St. Jude Medical, Inc. | System zur ausgabe und entnahme falt- und dehnbarer herzklappenprothesen |
WO2009094188A2 (en) | 2008-01-24 | 2009-07-30 | Medtronic, Inc. | Stents for prosthetic heart valves |
WO2009094500A1 (en) | 2008-01-24 | 2009-07-30 | Medtronic Vascular Inc. | Infundibular reducer device delivery system and related methods |
US7833265B2 (en) | 2008-03-13 | 2010-11-16 | Pacesetter, Inc. | Vascular anchoring system and method |
US8313525B2 (en) | 2008-03-18 | 2012-11-20 | Medtronic Ventor Technologies, Ltd. | Valve suturing and implantation procedures |
US20100131057A1 (en) | 2008-04-16 | 2010-05-27 | Cardiovascular Technologies, Llc | Transvalvular intraannular band for aortic valve repair |
BRPI0911351B8 (pt) | 2008-04-23 | 2021-06-22 | Medtronic Inc | estrutura de stent para uma válvula cardíaca protética, e, prótese de válvula cardíaca |
US20090276040A1 (en) | 2008-05-01 | 2009-11-05 | Edwards Lifesciences Corporation | Device and method for replacing mitral valve |
US9061119B2 (en) | 2008-05-09 | 2015-06-23 | Edwards Lifesciences Corporation | Low profile delivery system for transcatheter heart valve |
EP3476368B1 (de) | 2008-06-06 | 2020-01-01 | Edwards Lifesciences Corporation | Transkatheterherzklappe mit niedrigem profil |
US8323335B2 (en) | 2008-06-20 | 2012-12-04 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves and methods for using |
EP2303384B1 (de) | 2008-06-23 | 2015-08-12 | Lumen Biomedical, Inc. | Embolieschutz bei einem perkutanen herzklappenaustausch und ähnlichen prozeduren |
US8016417B2 (en) * | 2008-07-02 | 2011-09-13 | Abraham Reichert | Eye model |
CA2641297A1 (en) * | 2008-07-11 | 2010-01-11 | Richard B. Dorshow | Pyrazine derivatives, methods of use, and methods for preparing same |
US8652202B2 (en) | 2008-08-22 | 2014-02-18 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US20110224655A1 (en) | 2008-09-11 | 2011-09-15 | Asirvatham Samuel J | Central core multifunctional cardiac devices |
CA2749026C (en) | 2008-09-29 | 2018-01-09 | Impala, Inc. | Heart valve |
EP2358297B1 (de) * | 2008-11-21 | 2019-09-11 | Percutaneous Cardiovascular Solutions Pty Limited | Herzklappenprothese |
US8591573B2 (en) | 2008-12-08 | 2013-11-26 | Hector Daniel Barone | Prosthetic valve for intraluminal implantation |
US8147542B2 (en) | 2008-12-22 | 2012-04-03 | Valtech Cardio, Ltd. | Adjustable repair chords and spool mechanism therefor |
US8911494B2 (en) | 2009-05-04 | 2014-12-16 | Valtech Cardio, Ltd. | Deployment techniques for annuloplasty ring |
ES2873182T3 (es) | 2008-12-22 | 2021-11-03 | Valtech Cardio Ltd | Dispositivos de anuloplastia ajustables |
US20100210899A1 (en) | 2009-01-21 | 2010-08-19 | Tendyne Medical, Inc. | Method for percutaneous lateral access to the left ventricle for treatment of mitral insufficiency by papillary muscle alignment |
US20100185278A1 (en) | 2009-01-21 | 2010-07-22 | Tendyne Medical | Apical Papillary Msucle Attachment for Left Ventricular Reduction |
EP2395944B1 (de) * | 2009-02-11 | 2020-09-23 | Georg Lutter | Kathetersystem zur Rekonstruktion einer anatomischen Struktur |
WO2010093837A2 (en) | 2009-02-11 | 2010-08-19 | Tendyne Medical, Inc. | Percutaneous mitral annular stitch to decrease mitral regurgitation |
US20100217382A1 (en) | 2009-02-25 | 2010-08-26 | Edwards Lifesciences | Mitral valve replacement with atrial anchoring |
JP5659168B2 (ja) | 2009-02-27 | 2015-01-28 | セント・ジュード・メディカル,インコーポレイテッド | 折畳み可能な人工心臓弁用ステント特徴部 |
US20100249489A1 (en) | 2009-03-27 | 2010-09-30 | Robert Jarvik | Intraventricular blood pumps anchored by expandable mounting devices |
US9011522B2 (en) | 2009-04-10 | 2015-04-21 | Lon Sutherland ANNEST | Device and method for temporary or permanent suspension of an implantable scaffolding containing an orifice for placement of a prosthetic or bio-prosthetic valve |
WO2010121076A2 (en) | 2009-04-15 | 2010-10-21 | Cardiaq Valve Technologies, Inc. | Vascular implant and delivery system |
US8348998B2 (en) | 2009-06-26 | 2013-01-08 | Edwards Lifesciences Corporation | Unitary quick connect prosthetic heart valve and deployment system and methods |
FR2947716B1 (fr) | 2009-07-10 | 2011-09-02 | Cormove | Implant prothetique ameliore |
US8475522B2 (en) | 2009-07-14 | 2013-07-02 | Edwards Lifesciences Corporation | Transapical delivery system for heart valves |
US8845722B2 (en) | 2009-08-03 | 2014-09-30 | Shlomo Gabbay | Heart valve prosthesis and method of implantation thereof |
US20120130391A1 (en) | 2009-08-06 | 2012-05-24 | Mayo Foundation For Medical Education And Research | Implanting organ ports |
US8979933B2 (en) | 2009-08-06 | 2015-03-17 | Alphatec Spine, Inc. | Stand-alone interbody fixation system |
EP2467104B1 (de) | 2009-08-20 | 2016-11-02 | Cook Medical Technologies LLC | Ladegerät und system für expandierbare intraluminale medizinische vorrichtungen |
US9730790B2 (en) | 2009-09-29 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Replacement valve and method |
US9539081B2 (en) | 2009-12-02 | 2017-01-10 | Surefire Medical, Inc. | Method of operating a microvalve protection device |
US20130190861A1 (en) | 2012-01-23 | 2013-07-25 | Tendyne Holdings, Inc. | Prosthetic Valve for Replacing Mitral Valve |
US8449599B2 (en) * | 2009-12-04 | 2013-05-28 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
WO2011072084A2 (en) | 2009-12-08 | 2011-06-16 | Avalon Medical Ltd. | Device and system for transcatheter mitral valve replacement |
WO2011080588A2 (en) | 2009-12-30 | 2011-07-07 | Vivasure Medical Limited | Closure system and uses thereof |
US8475525B2 (en) | 2010-01-22 | 2013-07-02 | 4Tech Inc. | Tricuspid valve repair using tension |
US9522062B2 (en) * | 2010-02-24 | 2016-12-20 | Medtronic Ventor Technologies, Ltd. | Mitral prosthesis and methods for implantation |
US8460316B2 (en) | 2010-02-26 | 2013-06-11 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for endoluminal valve creation |
ES2922283T3 (es) | 2010-03-05 | 2022-09-12 | Edwards Lifesciences Corp | Mecanismos de retención para válvulas protésicas |
US8795354B2 (en) | 2010-03-05 | 2014-08-05 | Edwards Lifesciences Corporation | Low-profile heart valve and delivery system |
US9480557B2 (en) | 2010-03-25 | 2016-11-01 | Medtronic, Inc. | Stents for prosthetic heart valves |
SE535140C2 (sv) | 2010-03-25 | 2012-04-24 | Jan Otto Solem | En implanterbar anordning, kit och system för förbättring av hjärtfunktionen, innefattande medel för generering av longitudinell rörelse av mitralisklaffen |
US8652204B2 (en) | 2010-04-01 | 2014-02-18 | Medtronic, Inc. | Transcatheter valve with torsion spring fixation and related systems and methods |
US8512401B2 (en) | 2010-04-12 | 2013-08-20 | Medtronic, Inc. | Transcatheter prosthetic heart valve delivery system with funnel recapturing feature and method |
EP3858293A1 (de) | 2010-04-21 | 2021-08-04 | Medtronic, Inc. | Prothesenklappe mit dichtungselementen |
EP2560589B1 (de) | 2010-04-23 | 2018-06-06 | Medtronic, Inc. | Freisetzungssysteme für herzklappenprothesen |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
US9603708B2 (en) | 2010-05-19 | 2017-03-28 | Dfm, Llc | Low crossing profile delivery catheter for cardiovascular prosthetic implant |
US8790394B2 (en) | 2010-05-24 | 2014-07-29 | Valtech Cardio, Ltd. | Adjustable artificial chordeae tendineae with suture loops |
US20130190860A1 (en) | 2010-06-15 | 2013-07-25 | Mayo Foundation For Medical Education And Research | Percutaneously deliverable valves |
US20130030522A1 (en) | 2010-06-16 | 2013-01-31 | Rowe Stanton J | Devices and methods for heart treatments |
US9795476B2 (en) | 2010-06-17 | 2017-10-24 | St. Jude Medical, Llc | Collapsible heart valve with angled frame |
JP6125999B2 (ja) | 2010-06-21 | 2017-05-10 | カルディアック バルブ テクノロジーズ,インコーポレーテッド | 人工心臓弁 |
US8992604B2 (en) | 2010-07-21 | 2015-03-31 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
PL2598086T3 (pl) | 2010-07-30 | 2017-06-30 | Cook Medical Technologies Llc | Urządzenie do umieszczania protezy z kontrolowanym zwalnianiem i odzyskiwaniem |
US9039759B2 (en) | 2010-08-24 | 2015-05-26 | St. Jude Medical, Cardiology Division, Inc. | Repositioning of prosthetic heart valve and deployment |
CA2809262C (en) | 2010-08-24 | 2020-03-10 | Southern Lights Ventures 2002 Limited | Biomaterials with enhanced properties and devices made therefrom |
WO2012025927A2 (en) | 2010-08-25 | 2012-03-01 | Cardiapex Ltd. | Minimally invasive surgical techniques |
AU2011302641B2 (en) | 2010-09-17 | 2014-10-02 | St. Jude Medical, Cardiology Division, Inc. | Assembly and method for loading a self-expanding collapsible heart valve |
US10321998B2 (en) | 2010-09-23 | 2019-06-18 | Transmural Systems Llc | Methods and systems for delivering prostheses using rail techniques |
EP3001978B2 (de) | 2010-09-23 | 2023-03-01 | Edwards Lifesciences CardiAQ LLC | Künstliche herzklappen sowie vorrichtungen und verfahren zu ihrem einsatz |
CN111265338B (zh) | 2010-10-05 | 2021-04-13 | 爱德华兹生命科学公司 | 人工心脏瓣膜 |
EP2624765A2 (de) | 2010-10-07 | 2013-08-14 | Boston Scientific Scimed, Inc. | Biologisch abbaubarer klebstofffilm für gefässverschluss |
EP2629699B1 (de) * | 2010-10-21 | 2017-01-04 | Medtronic, Inc. | Mitralbioprothese mit niedrigem ventrikulären profil |
JP2014502859A (ja) | 2010-11-18 | 2014-02-06 | パビリオン・メディカル・イノベーションズ・リミテッド・ライアビリティ・カンパニー | 組織拘束装置及び使用方法 |
US9579197B2 (en) | 2010-12-15 | 2017-02-28 | Medtronic Vascular, Inc. | Systems and methods for positioning a heart valve using visual markers |
WO2012087842A1 (en) | 2010-12-23 | 2012-06-28 | The Foundry, Llc | System for mitral valve repair and replacement |
US20130274874A1 (en) | 2010-12-29 | 2013-10-17 | Children's Medical Center Corporation | Curved fiber arrangement for prosthetic heart valves |
US9687342B2 (en) | 2011-01-11 | 2017-06-27 | Hans Reiner Figulla | Valve prosthesis for replacing an atrioventricular valve of the heart with anchoring element |
US8845717B2 (en) | 2011-01-28 | 2014-09-30 | Middle Park Medical, Inc. | Coaptation enhancement implant, system, and method |
US8888843B2 (en) | 2011-01-28 | 2014-11-18 | Middle Peak Medical, Inc. | Device, system, and method for transcatheter treatment of valve regurgitation |
GB2488107B (en) | 2011-02-11 | 2013-03-06 | Cook Medical Technologies Llc | Drive assembly for facilitating deployment of an implantable medical device |
US8454656B2 (en) | 2011-03-01 | 2013-06-04 | Medtronic Ventor Technologies Ltd. | Self-suturing anchors |
US9039713B2 (en) | 2011-05-13 | 2015-05-26 | Merit Medical Systems, Inc. | Releasably attached snare loop retrieval device and method of using the same |
EP3964176A1 (de) | 2011-06-21 | 2022-03-09 | Twelve, Inc. | Herzklappenprothesenvorrichtungen |
WO2013011502A2 (en) | 2011-07-21 | 2013-01-24 | 4Tech Inc. | Method and apparatus for tricuspid valve repair using tension |
US9161837B2 (en) | 2011-07-27 | 2015-10-20 | The Cleveland Clinic Foundation | Apparatus, system, and method for treating a regurgitant heart valve |
WO2013021374A2 (en) | 2011-08-05 | 2013-02-14 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US20140324164A1 (en) | 2011-08-05 | 2014-10-30 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
EP3403616B1 (de) | 2011-08-11 | 2022-05-11 | Tendyne Holdings, Inc. | Verbesserungen für prothesenklappen und damit zusammenhängende erfindungen |
US9216076B2 (en) | 2011-09-09 | 2015-12-22 | Endoluminal Sciences Pty. Ltd. | Means for controlled sealing of endovascular devices |
US9011468B2 (en) | 2011-09-13 | 2015-04-21 | Abbott Cardiovascular Systems Inc. | Independent gripper |
US8900295B2 (en) | 2011-09-26 | 2014-12-02 | Edwards Lifesciences Corporation | Prosthetic valve with ventricular tethers |
WO2013045262A1 (en) | 2011-09-30 | 2013-04-04 | Jenavalve Technology Inc. | System and method for loading a stent into a medical delivery system |
US9763780B2 (en) | 2011-10-19 | 2017-09-19 | Twelve, Inc. | Devices, systems and methods for heart valve replacement |
WO2013059747A1 (en) | 2011-10-19 | 2013-04-25 | Foundry Newco Xii, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US8858623B2 (en) | 2011-11-04 | 2014-10-14 | Valtech Cardio, Ltd. | Implant having multiple rotational assemblies |
EP2591754B1 (de) | 2011-11-10 | 2015-02-25 | Medtentia International Ltd Oy | Vorrichtung und Verfahren zur Verbesserung der Funktion einer Herzklappe |
US9827092B2 (en) | 2011-12-16 | 2017-11-28 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
US9078645B2 (en) | 2011-12-19 | 2015-07-14 | Edwards Lifesciences Corporation | Knotless suture anchoring devices and tools for implants |
WO2013096757A1 (en) | 2011-12-21 | 2013-06-27 | The Trustees Of The University Of Pennsylvania | Mechanical myocardial restraint device |
US9078747B2 (en) | 2011-12-21 | 2015-07-14 | Edwards Lifesciences Corporation | Anchoring device for replacing or repairing a heart valve |
WO2013103612A1 (en) | 2012-01-04 | 2013-07-11 | Tendyne Holdings, Inc. | Improved multi-component cuff designs for transcatheter mitral valve replacement, subvalvular sealing apparatus for transcatheter mitral valves and wire framed leaflet assembly |
US20130184811A1 (en) | 2012-01-13 | 2013-07-18 | Tendyne Holdings, Inc. | Device and Method for Replacing Mitral Valve |
EP2814427B1 (de) | 2012-02-15 | 2018-12-12 | Children's Hospital Boston | Rechtsventrikuläre papillare annäherung |
US20150094802A1 (en) | 2012-02-28 | 2015-04-02 | Mvalve Technologies Ltd. | Single-ring cardiac valve support |
US9579198B2 (en) | 2012-03-01 | 2017-02-28 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
EP2825203B1 (de) | 2012-03-12 | 2020-11-18 | Colorado State University Research Foundation | Glycosaminoglycan und synthetische polymermaterialien für blutkontaktierende anwendungen |
US9636223B2 (en) | 2012-05-16 | 2017-05-02 | Edwards Lifesciences Corporation | Systems and methods for placing a coapting member between valvular leaflets |
CA2874208C (en) | 2012-05-20 | 2020-05-12 | Mitralheal Ltd. | Prosthetic mitral valve |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US9233015B2 (en) | 2012-06-15 | 2016-01-12 | Trivascular, Inc. | Endovascular delivery system with an improved radiopaque marker scheme |
US9883941B2 (en) | 2012-06-19 | 2018-02-06 | Boston Scientific Scimed, Inc. | Replacement heart valve |
WO2014022124A1 (en) | 2012-07-28 | 2014-02-06 | Tendyne Holdings, Inc. | Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
WO2014021905A1 (en) | 2012-07-30 | 2014-02-06 | Tendyne Holdings, Inc. | Improved delivery systems and methods for transcatheter prosthetic valves |
US10206775B2 (en) | 2012-08-13 | 2019-02-19 | Medtronic, Inc. | Heart valve prosthesis |
US9232995B2 (en) | 2013-01-08 | 2016-01-12 | Medtronic, Inc. | Valve prosthesis and method for delivery |
US9468525B2 (en) | 2012-08-13 | 2016-10-18 | Medtronic, Inc. | Heart valve prosthesis |
DE102012107465A1 (de) | 2012-08-15 | 2014-05-22 | Pfm Medical Ag | Implantierbare Einrichtung zur Verwendung im menschlichen und/oder tierischen Körper zum Ersatz einer Organklappe |
US9510946B2 (en) | 2012-09-06 | 2016-12-06 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US9610156B2 (en) | 2012-09-14 | 2017-04-04 | Millipede, Inc. | Mitral valve inversion prostheses |
US9138221B2 (en) | 2012-09-20 | 2015-09-22 | Medos International Sarl | Anti-backup suture anchor |
US9023099B2 (en) | 2012-10-31 | 2015-05-05 | Medtronic Vascular Galway Limited | Prosthetic mitral valve and delivery method |
EP2732796A1 (de) | 2012-11-20 | 2014-05-21 | Nakostech Sarl | Mitralklappenersatzsystem |
US9066801B2 (en) | 2013-01-08 | 2015-06-30 | Medtronic, Inc. | Valve prosthesis and method for delivery |
US9132007B2 (en) | 2013-01-10 | 2015-09-15 | Medtronic CV Luxembourg S.a.r.l. | Anti-paravalvular leakage components for a transcatheter valve prosthesis |
ES2934670T3 (es) | 2013-01-24 | 2023-02-23 | Cardiovalve Ltd | Válvulas protésicas ancladas de forma ventricular |
US9675451B2 (en) | 2013-02-01 | 2017-06-13 | Medtronic CV Luxembourg S.a.r.l. | Anti-paravalvular leakage component for a transcatheter valve prosthesis |
CN109938878B (zh) | 2013-02-04 | 2021-08-31 | 托尔福公司 | 用于人工心脏瓣膜装置的液压输送系统及相关方法 |
US10080657B2 (en) | 2013-03-07 | 2018-09-25 | Cedars-Sinai Medical Center | Catheter based apical approach heart prostheses delivery system |
US8986375B2 (en) | 2013-03-12 | 2015-03-24 | Medtronic, Inc. | Anti-paravalvular leakage component for a transcatheter valve prosthesis |
CN105142574B (zh) | 2013-03-15 | 2017-12-01 | 爱德华兹生命科学公司 | 带瓣主动脉管道 |
US9232998B2 (en) | 2013-03-15 | 2016-01-12 | Cardiosolutions Inc. | Trans-apical implant systems, implants and methods |
US9289297B2 (en) | 2013-03-15 | 2016-03-22 | Cardiosolutions, Inc. | Mitral valve spacer and system and method for implanting the same |
EP4183373A1 (de) | 2013-03-15 | 2023-05-24 | Twelve, Inc. | Herzklappenprothesenvorrichtungen, mitralklappenprothesen sowie zugehörige systeme |
US20140296971A1 (en) | 2013-04-02 | 2014-10-02 | Tendyne Holdings | Alignment Device for Asymmetric Transcatheter Valve |
US20140296972A1 (en) | 2013-04-02 | 2014-10-02 | Tendyne Holdings | Deployment Compensator for Transcatheter Valve Delivery |
US20140296970A1 (en) | 2013-04-02 | 2014-10-02 | Tendyne Holdings, Inc. | Positioning Tool for Transcatheter Valve Delivery |
WO2015065646A1 (en) | 2013-10-28 | 2015-05-07 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US20140296969A1 (en) | 2013-04-02 | 2014-10-02 | Tendyne Holdlings, Inc. | Anterior Leaflet Clip Device for Prosthetic Mitral Valve |
WO2014162306A2 (en) | 2013-04-02 | 2014-10-09 | Tendyne Holdings, Inc. | Improved devices and methods for transcatheter prosthetic heart valves |
US10463489B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US9486306B2 (en) | 2013-04-02 | 2016-11-08 | Tendyne Holdings, Inc. | Inflatable annular sealing device for prosthetic mitral valve |
US20140303718A1 (en) | 2013-04-04 | 2014-10-09 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
US10478293B2 (en) | 2013-04-04 | 2019-11-19 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
US10188515B2 (en) | 2013-05-13 | 2019-01-29 | Medtronic Vascular Inc. | Devices and methods for crimping a medical device |
CA2908342C (en) | 2013-05-20 | 2021-11-30 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
CN108294846A (zh) | 2013-05-20 | 2018-07-20 | 托尔福公司 | 可植入心脏瓣膜装置、二尖瓣修复装置以及相关系统和方法 |
US20140358224A1 (en) | 2013-05-30 | 2014-12-04 | Tendyne Holdlings, Inc. | Six cell inner stent device for prosthetic mitral valves |
US9610159B2 (en) | 2013-05-30 | 2017-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
WO2014203171A1 (en) | 2013-06-17 | 2014-12-24 | Heldman Alan | Prosthetic heart valve with linking element and methods for implanting same |
WO2014210124A1 (en) | 2013-06-25 | 2014-12-31 | Mark Christianson | Thrombus management and structural compliance features for prosthetic heart valves |
US20140379076A1 (en) | 2013-06-25 | 2014-12-25 | Tendyne Holdings, Inc. | Halo Wire Fluid Seal Device for Prosthetic Mitral Valves |
US20150005874A1 (en) | 2013-06-27 | 2015-01-01 | Tendyne Holdings, Inc. | Atrial Thrombogenic Sealing Pockets for Prosthetic Mitral Valves |
US20150057705A1 (en) | 2013-08-01 | 2015-02-26 | Tendyne Holdings, Inc. | Pursestring Epicardial Pad Device |
CA2919379C (en) | 2013-08-01 | 2021-03-30 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
US10195028B2 (en) | 2013-09-10 | 2019-02-05 | Edwards Lifesciences Corporation | Magnetic retaining mechanisms for prosthetic valves |
EP3043745B1 (de) | 2013-09-12 | 2020-10-21 | St. Jude Medical, Cardiology Division, Inc. | Stententwürfe für herzklappenprothesen |
WO2015051430A1 (pt) | 2013-10-10 | 2015-04-16 | Neves Filho Antonio Francisco | Disposição introduzida em suporte para plastia ou troca de válvula cardíaca |
WO2015058039A1 (en) | 2013-10-17 | 2015-04-23 | Robert Vidlund | Apparatus and methods for alignment and deployment of intracardiac devices |
US9526611B2 (en) | 2013-10-29 | 2016-12-27 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US10022114B2 (en) | 2013-10-30 | 2018-07-17 | 4Tech Inc. | Percutaneous tether locking |
WO2015063580A2 (en) | 2013-10-30 | 2015-05-07 | 4Tech Inc. | Multiple anchoring-point tension system |
CN106562840B (zh) | 2013-10-31 | 2018-06-22 | 上海微创心通医疗科技有限公司 | 一种将植入体装载到输送系统中的导引盖和装载系统 |
US9889004B2 (en) | 2013-11-19 | 2018-02-13 | St. Jude Medical, Cardiology Division, Inc. | Sealing structures for paravalvular leak protection |
US9848880B2 (en) | 2013-11-20 | 2017-12-26 | James E. Coleman | Adjustable heart valve implant |
WO2015120122A2 (en) | 2014-02-05 | 2015-08-13 | Robert Vidlund | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
US10292711B2 (en) | 2014-02-07 | 2019-05-21 | St. Jude Medical, Cardiology Division, Inc. | Mitral valve treatment device having left atrial appendage closure |
US9986993B2 (en) | 2014-02-11 | 2018-06-05 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
US20150238729A1 (en) | 2014-02-24 | 2015-08-27 | Mark Lynn Jenson | Cardiac Access Catheter, System, and Method |
EP3116409B1 (de) | 2014-03-10 | 2023-07-26 | Tendyne Holdings, Inc. | Vorrichtungen zur positionierung und überwachung der gurtbelastung für eine künstliche mitralklappe |
EP2918248A1 (de) | 2014-03-11 | 2015-09-16 | Epygon Sasu | Ausdehnbare Stentklappe und Abgabevorrichtung |
US10149758B2 (en) | 2014-04-01 | 2018-12-11 | Medtronic, Inc. | System and method of stepped deployment of prosthetic heart valve |
US10321987B2 (en) | 2014-04-23 | 2019-06-18 | Medtronic, Inc. | Paravalvular leak resistant prosthetic heart valve system |
CN106456321B (zh) | 2014-05-14 | 2019-08-27 | 索林集团意大利有限责任公司 | 植入设备与植入套件 |
WO2015175450A1 (en) | 2014-05-16 | 2015-11-19 | St. Jude Medical, Cardiology Division, Inc. | Transcatheter valve with paravalvular leak sealing ring |
WO2015184450A1 (en) | 2014-05-30 | 2015-12-03 | Cardiac Valve Solutions Llc | Temporary valve and filter on guide catheter |
US10111749B2 (en) | 2014-06-11 | 2018-10-30 | Medtronic Vascular, Inc. | Prosthetic valve with flow director |
CN107405195B (zh) | 2015-01-07 | 2020-09-08 | 坦迪尼控股股份有限公司 | 人造二尖瓣以及用于递送人造二尖瓣的设备和方法 |
AU2016215197B2 (en) | 2015-02-05 | 2020-01-02 | Tendyne Holdings Inc. | Expandable epicardial pads and devices and methods for their delivery |
US9321386B1 (en) | 2015-02-20 | 2016-04-26 | Vermeer Manufacturing Company | Low profile compact tool carriers |
JP6694948B2 (ja) | 2015-04-16 | 2020-05-20 | テンダイン ホールディングス,インコーポレイテッド | 経カテーテル人工弁の送達、再配置及び回収のための装置及び方法 |
JP6842427B2 (ja) | 2015-06-05 | 2021-03-17 | テンダイン ホールディングス,インコーポレイテッド | 人工僧帽弁の経血管送達の先端制御 |
US10327894B2 (en) | 2015-09-18 | 2019-06-25 | Tendyne Holdings, Inc. | Methods for delivery of prosthetic mitral valves |
AU2016362474B2 (en) | 2015-12-03 | 2021-04-22 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves |
CA3006010C (en) | 2015-12-28 | 2023-09-26 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
US20170209268A1 (en) | 2016-01-27 | 2017-07-27 | Medtronic, Inc. | Systems and methods for repositioning a fully deployed valve assembly |
US10470877B2 (en) | 2016-05-03 | 2019-11-12 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
EP3468480B1 (de) | 2016-06-13 | 2023-01-11 | Tendyne Holdings, Inc. | Sequenzielle freisetzung einer zweiteiligen mitralklappenprothese |
EP3478224B1 (de) | 2016-06-30 | 2022-11-02 | Tendyne Holdings, Inc. | Herzklappenprothesen sowie vorrichtung zur einführung davon |
WO2018013515A1 (en) | 2016-07-12 | 2018-01-18 | Tendyne Holdings, Inc. | Apparatus and methods for trans-septal retrieval of prosthetic heart valves |
-
2007
- 2007-09-13 DE DE102007043830A patent/DE102007043830A1/de not_active Withdrawn
-
2008
- 2008-09-10 ES ES08801319.8T patent/ES2445589T3/es active Active
- 2008-09-10 EP EP08801319.8A patent/EP2194925B1/de active Active
- 2008-09-10 DE DE202008018461.4U patent/DE202008018461U1/de not_active Expired - Lifetime
- 2008-09-10 DE DE202008018459.2U patent/DE202008018459U1/de not_active Expired - Lifetime
- 2008-09-10 US US12/677,958 patent/US20110004296A1/en not_active Abandoned
- 2008-09-10 DE DE202008018470.3U patent/DE202008018470U1/de not_active Expired - Lifetime
- 2008-09-10 WO PCT/DE2008/001515 patent/WO2009033469A1/de active Application Filing
- 2008-09-10 DE DE202008018458.4U patent/DE202008018458U1/de not_active Expired - Lifetime
-
2011
- 2011-10-18 US US13/275,751 patent/US20120035703A1/en not_active Abandoned
- 2011-10-18 US US13/275,683 patent/US9095433B2/en active Active
-
2012
- 2012-05-04 US US13/464,367 patent/US20120283824A1/en not_active Abandoned
-
2014
- 2014-08-21 US US14/465,437 patent/US9078749B2/en active Active
-
2015
- 2015-06-22 US US14/746,381 patent/US9254192B2/en active Active
-
2016
- 2016-02-08 US US15/018,473 patent/US9730792B2/en active Active
-
2017
- 2017-07-19 US US15/653,653 patent/US10456248B2/en active Active
-
2019
- 2019-09-10 US US16/565,564 patent/US11213387B2/en active Active
-
2021
- 2021-10-20 US US17/505,734 patent/US20220039947A1/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19546692C2 (de) | 1995-12-14 | 2002-11-07 | Hans-Reiner Figulla | Selbstexpandierende Herzklappenprothese zur Implantation im menschlichen Körper über ein Kathetersystem |
US20070050020A1 (en) | 2000-02-02 | 2007-03-01 | Spence Paul A | Heart valve repair apparatus and methods |
DE10010074A1 (de) | 2000-02-28 | 2001-10-18 | Fraunhofer Ges Forschung | Vorrichtung zur Befestigung und Verankerung von Herzklappenprothesen |
US20030078652A1 (en) | 2001-10-23 | 2003-04-24 | Sutherland Fraser W.H. | Heart valve prosthesis |
US20050075727A1 (en) | 2001-10-29 | 2005-04-07 | Wheatley David John | Mitral valve prosthesis |
EP1469797A1 (de) | 2002-08-13 | 2004-10-27 | Hans-Reiner Figulla | Vorrichtung zur implantation und befestigung von herzklappenprothesen |
EP1469797B1 (de) | 2002-08-13 | 2005-11-02 | Hans-Reiner Figulla | Vorrichtung zur implantation und befestigung von herzklappenprothesen |
Cited By (400)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9095432B2 (en) | 1996-12-31 | 2015-08-04 | Edwards Lifesciences Pvt, Inc. | Collapsible prosthetic valve having an internal cover |
US9486312B2 (en) | 1996-12-31 | 2016-11-08 | Edwards Lifesciences Pvt, Inc. | Method of manufacturing a prosthetic valve |
US9629714B2 (en) | 1996-12-31 | 2017-04-25 | Edwards Lifesciences Pvt, Inc. | Collapsible prosthetic valve |
US9364354B2 (en) | 2000-03-27 | 2016-06-14 | Neovasc Medical Ltd | Methods for treating abnormal growths in the body using a flow reducing implant |
US10542994B2 (en) | 2000-03-27 | 2020-01-28 | Neovasc Medical Ltd. | Methods for treating abnormal growths in the body using a flow reducing implant |
US11497503B2 (en) | 2000-03-27 | 2022-11-15 | Neovasc Medical Ltd. | Methods for treating abnormal growths in the body using a flow reducing implant |
US10022220B2 (en) | 2000-04-06 | 2018-07-17 | Edwards Lifesciences Corporation | Methods of implanting minimally-invasive prosthetic heart valves |
US9241788B2 (en) | 2001-03-23 | 2016-01-26 | Edwards Lifesciences Corporation | Method for treating an aortic valve |
US9707074B2 (en) | 2001-03-23 | 2017-07-18 | Edwards Lifesciences Corporation | Method for treating an aortic valve |
US9132006B2 (en) | 2001-10-11 | 2015-09-15 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US11076955B2 (en) | 2003-10-02 | 2021-08-03 | Edwards Lifesciences Corporation | Implantable prosthetic heart valve |
US10154900B2 (en) | 2003-10-02 | 2018-12-18 | Edwards Lifesciences Corporation | Implantable prosthetic valve with non-laminar flow |
US10772723B2 (en) | 2003-10-02 | 2020-09-15 | Edwards Lifesciences Corporation | Implantable prosthetic valve with non-laminar flow |
US9744059B2 (en) | 2003-11-19 | 2017-08-29 | Neovasc Medical Ltd. | Vascular implant |
US11564818B2 (en) | 2003-11-19 | 2023-01-31 | Neovase Medical Ltd. | Vascular implant |
US11304803B2 (en) | 2004-10-02 | 2022-04-19 | Edwards Lifesciences Cardiaq Llc | Method for replacement of heart valve |
US11058536B2 (en) | 2004-10-02 | 2021-07-13 | Edwards Lifesciences Cardiaq Llc | Method for replacement of heart valve |
US9974669B2 (en) | 2005-11-10 | 2018-05-22 | Edwards Lifesciences Cardiaq Llc | Percutaneous heart valve |
US10456277B2 (en) | 2005-11-10 | 2019-10-29 | Edwards Lifesciences Cardiaq Llc | Percutaneous heart valve |
US10350065B2 (en) | 2006-07-28 | 2019-07-16 | Edwards Lifesciences Cardiaq Llc | Percutaneous valve prosthesis and system and method for implanting the same |
US11141265B2 (en) | 2006-07-28 | 2021-10-12 | Edwards Lifesciences Cardiaq Llc | Percutaneous valve prosthesis and system and method for implanting the same |
US10925760B2 (en) | 2006-07-31 | 2021-02-23 | Edwards Lifesciences Cardiaq Llc | Sealable endovascular implants and methods for their use |
US11877941B2 (en) | 2006-07-31 | 2024-01-23 | Edwards Lifesciences Cardiaq Llc | Sealable endovascular implants and methods for their use |
US10687968B2 (en) | 2006-07-31 | 2020-06-23 | Edwards Lifesciences Cardiaq Llc | Sealable endovascular implants and methods for their use |
US10507097B2 (en) | 2006-07-31 | 2019-12-17 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US9114008B2 (en) | 2006-12-22 | 2015-08-25 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method for making the same |
US9095433B2 (en) | 2007-09-13 | 2015-08-04 | Georg Lutter | Truncated cone heart valve stent |
US11213387B2 (en) | 2007-09-13 | 2022-01-04 | Georg Lutter | Truncated cone heart valve stent |
US9254192B2 (en) | 2007-09-13 | 2016-02-09 | Georg Lutter | Truncated cone heart valve stent |
US9078749B2 (en) | 2007-09-13 | 2015-07-14 | Georg Lutter | Truncated cone heart valve stent |
US10413406B2 (en) | 2007-12-14 | 2019-09-17 | Edwards Lifesciences Corporation | Leaflet attachment frame for a prosthetic valve |
US10413404B2 (en) | 2007-12-14 | 2019-09-17 | Edwards Lifesciences Corporation | Leaflet attachment frame for a prosthetic valve |
US10413405B2 (en) | 2007-12-14 | 2019-09-17 | Edwards Lifesciences Corporation | Leaflet attachment frame for a prosthetic valve |
US9173737B2 (en) | 2008-04-23 | 2015-11-03 | Medtronic, Inc. | Stented heart valve devices |
US10548723B2 (en) | 2008-04-23 | 2020-02-04 | Medtronic, Inc. | Prosthetic heart valve devices and methods of valve replacement |
EP3967274B1 (de) | 2008-04-23 | 2022-08-24 | Medtronic, Inc. | Herzklappenvorrichtungen mit stent |
US8323336B2 (en) | 2008-04-23 | 2012-12-04 | Medtronic, Inc. | Prosthetic heart valve devices and methods of valve replacement |
US9827090B2 (en) | 2008-04-23 | 2017-11-28 | Medtronic, Inc. | Prosthetic heart valve devices and methods of valve replacement |
EP3549555B1 (de) | 2008-05-01 | 2021-06-16 | Edwards Lifesciences Corporation | Künstliche mitralklappenanordnung |
US11717401B2 (en) | 2008-05-01 | 2023-08-08 | Edwards Lifesciences Corporation | Prosthetic heart valve assembly |
US10617520B2 (en) | 2008-05-01 | 2020-04-14 | Edwards Lifesciences Corporation | Method of replacing mitral valve |
EP3132773B1 (de) | 2008-05-01 | 2017-11-22 | Edwards Lifesciences Corporation | Vorrichtung zum austausch einer mitralklappe |
US10226334B2 (en) | 2008-05-01 | 2019-03-12 | Edwards Lifesciences Corporation | Method for replacing mitral valve |
WO2009134701A3 (en) * | 2008-05-01 | 2010-02-11 | Edwards Lifesciences Corporation | Device and method for replacing mitral valve |
EP3050541B1 (de) | 2008-05-01 | 2019-08-14 | Edwards Lifesciences Corporation | Künstliche mitralklappenanordnung |
EP2676640A1 (de) * | 2008-05-01 | 2013-12-25 | Edwards Lifesciences Corporation | Vorrichtung für Mitralklappenersatz |
US10952846B2 (en) | 2008-05-01 | 2021-03-23 | Edwards Lifesciences Corporation | Method of replacing mitral valve |
US10413407B2 (en) | 2008-06-06 | 2019-09-17 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US10292817B2 (en) | 2008-06-06 | 2019-05-21 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US11648111B2 (en) | 2008-06-06 | 2023-05-16 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US9662204B2 (en) | 2008-06-06 | 2017-05-30 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US10426611B2 (en) | 2008-06-06 | 2019-10-01 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US10492905B2 (en) | 2008-06-06 | 2019-12-03 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US11213388B2 (en) | 2008-06-06 | 2022-01-04 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US11696826B2 (en) | 2008-06-06 | 2023-07-11 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US11744701B2 (en) | 2008-06-06 | 2023-09-05 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US9993338B2 (en) | 2008-06-20 | 2018-06-12 | Edwards Lifesciences Corporation | Methods for retaining a prosthetic heart valve |
US10722355B2 (en) | 2008-06-20 | 2020-07-28 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US10966827B2 (en) | 2008-06-20 | 2021-04-06 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US9561101B2 (en) | 2008-06-20 | 2017-02-07 | Edwards Lifesciences Corporation | Two-part prosthetic valve system |
US11141270B2 (en) | 2008-08-22 | 2021-10-12 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11957582B2 (en) | 2008-08-22 | 2024-04-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11116632B2 (en) | 2008-08-22 | 2021-09-14 | Edwards Lifesciences Corporation | Transvascular delivery systems |
US9364325B2 (en) | 2008-08-22 | 2016-06-14 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery system and method |
US11540918B2 (en) | 2008-08-22 | 2023-01-03 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11116631B2 (en) | 2008-08-22 | 2021-09-14 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery methods |
US10238487B2 (en) | 2008-08-22 | 2019-03-26 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11730597B2 (en) | 2008-08-22 | 2023-08-22 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11109970B2 (en) | 2008-08-22 | 2021-09-07 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11690718B2 (en) | 2008-08-22 | 2023-07-04 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10820994B2 (en) | 2008-08-22 | 2020-11-03 | Edwards Lifesciences Corporation | Methods for delivering a prosthetic valve |
US10945839B2 (en) | 2008-08-22 | 2021-03-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10952848B2 (en) | 2008-08-22 | 2021-03-23 | Edwards Lifesciences Corporation | Methods of loading a prosthetic valve in a delivery apparatus |
US10932906B2 (en) | 2008-08-22 | 2021-03-02 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10149756B2 (en) | 2008-09-29 | 2018-12-11 | Edwards Lifesciences Cardiaq Llc | Heart valve |
US9456896B2 (en) | 2008-09-29 | 2016-10-04 | Edwards Lifesciences Cardiaq Llc | Body cavity prosthesis |
US11819404B2 (en) | 2008-09-29 | 2023-11-21 | Edwards Lifesciences Cardiaq Llc | Heart valve |
US11589983B2 (en) | 2008-09-29 | 2023-02-28 | Edwards Lifesciences Cardiaq Llc | Heart valve |
US10646334B2 (en) | 2008-09-29 | 2020-05-12 | Edwards Lifesciences Cardiaq Llc | Heart valve |
US9597183B2 (en) | 2008-10-01 | 2017-03-21 | Edwards Lifesciences Cardiaq Llc | Delivery system for vascular implant |
US11957576B2 (en) | 2008-10-10 | 2024-04-16 | Edwards Lifesciences Corporation | Expandable sheath for introducing an endovascular delivery device into a body |
US9333073B2 (en) | 2009-04-15 | 2016-05-10 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery method |
US11376119B2 (en) | 2009-04-15 | 2022-07-05 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US10441412B2 (en) | 2009-04-15 | 2019-10-15 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US9333074B2 (en) | 2009-04-15 | 2016-05-10 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US9339380B2 (en) | 2009-04-15 | 2016-05-17 | Edwards Lifesciences Cardiaq Llc | Vascular implant |
US9585747B2 (en) | 2009-04-15 | 2017-03-07 | Edwards Lifesciences Cardiaq Llc | Vascular implant |
US9339378B2 (en) | 2009-04-15 | 2016-05-17 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US9339379B2 (en) | 2009-04-15 | 2016-05-17 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US11766323B2 (en) | 2009-07-02 | 2023-09-26 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US10568732B2 (en) | 2009-07-02 | 2020-02-25 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US10500044B2 (en) | 2009-07-14 | 2019-12-10 | Edwards Lifesciences Corporation | Systems of heart valve delivery on a beating heart |
US9717594B2 (en) | 2009-07-14 | 2017-08-01 | Edwards Lifesciences Corporation | Methods of valve delivery on a beating heart |
US11458014B2 (en) | 2009-07-14 | 2022-10-04 | Edwards Lifesciences Corporation | Methods of heart valve delivery on a beating heart |
US9949827B2 (en) | 2009-09-29 | 2018-04-24 | Edwards Lifesciences Cardiaq Llc | Replacement heart valves, delivery devices and methods |
US9730790B2 (en) | 2009-09-29 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Replacement valve and method |
US9480560B2 (en) | 2009-09-29 | 2016-11-01 | Edwards Lifesciences Cardiaq Llc | Method of securing an intralumenal frame assembly |
US10524901B2 (en) | 2009-09-29 | 2020-01-07 | Edwards Lifesciences Cardiaq Llc | Replacement heart valve |
US10166097B2 (en) | 2009-09-29 | 2019-01-01 | Edwards Lifesciences Cardiaq Llc | Replacement heart valve and method |
US11839541B2 (en) | 2009-12-08 | 2023-12-12 | Cardiovalve Ltd. | Prosthetic heart valve with upper skirt |
US10231831B2 (en) | 2009-12-08 | 2019-03-19 | Cardiovalve Ltd. | Folding ring implant for heart valve |
US8870950B2 (en) | 2009-12-08 | 2014-10-28 | Mitral Tech Ltd. | Rotation-based anchoring of an implant |
US11351026B2 (en) | 2009-12-08 | 2022-06-07 | Cardiovalve Ltd. | Rotation-based anchoring of an implant |
US10548726B2 (en) | 2009-12-08 | 2020-02-04 | Cardiovalve Ltd. | Rotation-based anchoring of an implant |
US11141268B2 (en) | 2009-12-08 | 2021-10-12 | Cardiovalve Ltd. | Prosthetic heart valve with upper and lower skirts |
US10660751B2 (en) | 2009-12-08 | 2020-05-26 | Cardiovalve Ltd. | Prosthetic heart valve with upper skirt |
US10398546B2 (en) | 2010-02-24 | 2019-09-03 | Medtronic Ventor Technologies Ltd. | Mitral prosthesis and methods for implantation |
US9522062B2 (en) | 2010-02-24 | 2016-12-20 | Medtronic Ventor Technologies, Ltd. | Mitral prosthesis and methods for implantation |
WO2011106137A1 (en) * | 2010-02-24 | 2011-09-01 | Medtronic Inc. | Mitral prosthesis |
US11730589B2 (en) | 2010-03-05 | 2023-08-22 | Edwards Lifesciences Corporation | Prosthetic heart valve having an inner frame and an outer frame |
US11109964B2 (en) | 2010-03-10 | 2021-09-07 | Cardiovalve Ltd. | Axially-shortening prosthetic valve |
US11419720B2 (en) | 2010-05-05 | 2022-08-23 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
US11432924B2 (en) | 2010-05-05 | 2022-09-06 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US10449042B2 (en) | 2010-05-05 | 2019-10-22 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US9241790B2 (en) | 2010-05-05 | 2016-01-26 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US9248014B2 (en) | 2010-05-05 | 2016-02-02 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US9770329B2 (en) | 2010-05-05 | 2017-09-26 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US10485660B2 (en) | 2010-06-21 | 2019-11-26 | Edwards Lifesciences Cardiaq Llc | Replacement heart valve |
US11452597B2 (en) | 2010-06-21 | 2022-09-27 | Edwards Lifesciences Cardiaq Llc | Replacement heart valve |
US10639146B2 (en) | 2010-06-21 | 2020-05-05 | Edwards Lifesciences Cardiaq Llc | Replacement heart valve |
US11259921B2 (en) | 2010-07-09 | 2022-03-01 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11259922B2 (en) | 2010-07-09 | 2022-03-01 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9375312B2 (en) | 2010-07-09 | 2016-06-28 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11883283B2 (en) | 2010-07-09 | 2024-01-30 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9931206B2 (en) | 2010-07-09 | 2018-04-03 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11311377B2 (en) | 2010-07-09 | 2022-04-26 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11446140B2 (en) | 2010-07-09 | 2022-09-20 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9763657B2 (en) | 2010-07-21 | 2017-09-19 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US10512456B2 (en) | 2010-07-21 | 2019-12-24 | Cardiovalve Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US8992604B2 (en) | 2010-07-21 | 2015-03-31 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US11969163B2 (en) | 2010-07-21 | 2024-04-30 | Cardiovalve Ltd. | Valve prosthesis configured for deployment in annular spacer |
US9017399B2 (en) | 2010-07-21 | 2015-04-28 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US9132009B2 (en) | 2010-07-21 | 2015-09-15 | Mitraltech Ltd. | Guide wires with commissural anchors to advance a prosthetic valve |
US11653910B2 (en) | 2010-07-21 | 2023-05-23 | Cardiovalve Ltd. | Helical anchor implantation |
US10925595B2 (en) | 2010-07-21 | 2021-02-23 | Cardiovalve Ltd. | Valve prosthesis configured for deployment in annular spacer |
US10531872B2 (en) | 2010-07-21 | 2020-01-14 | Cardiovalve Ltd. | Valve prosthesis configured for deployment in annular spacer |
US11426155B2 (en) | 2010-07-21 | 2022-08-30 | Cardiovalve Ltd. | Helical anchor implantation |
US10500047B2 (en) | 2010-07-23 | 2019-12-10 | Edwards Lifesciences Corporation | Methods for delivering prosthetic valves to native heart valves |
US11696827B2 (en) | 2010-07-23 | 2023-07-11 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US11969344B2 (en) | 2010-07-23 | 2024-04-30 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US10881510B2 (en) | 2010-09-23 | 2021-01-05 | Edwards Lifesciences Cardiaq Llc | Replacement heart valves, delivery devices and methods |
US10610362B2 (en) | 2010-09-23 | 2020-04-07 | Edwards Lifesciences Cardiaq Llc | Replacement heart valves, delivery devices and methods |
US10433959B2 (en) | 2010-10-05 | 2019-10-08 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10478292B2 (en) | 2010-10-05 | 2019-11-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10537423B2 (en) | 2010-10-05 | 2020-01-21 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10433958B2 (en) | 2010-10-05 | 2019-10-08 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11540911B2 (en) | 2010-12-29 | 2023-01-03 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US11903825B2 (en) | 2011-02-23 | 2024-02-20 | Edwards Lifesciences Cardiaq Llc | Replacement heart valve and method |
US10779938B2 (en) | 2011-02-23 | 2020-09-22 | Edwards Lifesciences Cardiaq Llc | Replacement heart valve and method |
US11801132B2 (en) | 2011-02-25 | 2023-10-31 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11737871B2 (en) | 2011-02-25 | 2023-08-29 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10561494B2 (en) | 2011-02-25 | 2020-02-18 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US11737868B2 (en) | 2011-02-25 | 2023-08-29 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US11399934B2 (en) | 2011-02-25 | 2022-08-02 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11129713B2 (en) | 2011-02-25 | 2021-09-28 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US9713529B2 (en) | 2011-04-28 | 2017-07-25 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US11291542B2 (en) | 2011-07-27 | 2022-04-05 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US10856977B2 (en) | 2011-07-27 | 2020-12-08 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US10179047B2 (en) | 2011-07-27 | 2019-01-15 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US11554013B2 (en) | 2011-07-27 | 2023-01-17 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US11864997B2 (en) | 2011-07-27 | 2024-01-09 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US11877929B2 (en) | 2011-07-27 | 2024-01-23 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US11517436B2 (en) | 2011-08-05 | 2022-12-06 | Cardiovalve Ltd. | Implant for heart valve |
US11690712B2 (en) | 2011-08-05 | 2023-07-04 | Cardiovalve Ltd. | Clip-secured implant for heart valve |
US11517429B2 (en) | 2011-08-05 | 2022-12-06 | Cardiovalve Ltd. | Apparatus for use at a heart valve |
US10226341B2 (en) | 2011-08-05 | 2019-03-12 | Cardiovalve Ltd. | Implant for heart valve |
US11369469B2 (en) | 2011-08-05 | 2022-06-28 | Cardiovalve Ltd. | Method for use at a heart valve |
US10376361B2 (en) | 2011-08-05 | 2019-08-13 | Cardiovalve Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US11344410B2 (en) | 2011-08-05 | 2022-05-31 | Cardiovalve Ltd. | Implant for heart valve |
US8852272B2 (en) | 2011-08-05 | 2014-10-07 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US9387078B2 (en) | 2011-08-05 | 2016-07-12 | Mitraltech Ltd. | Percutaneous mitral valve replacement and sealing |
US10245143B2 (en) | 2011-08-05 | 2019-04-02 | Cardiovalve Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US11291546B2 (en) | 2011-08-05 | 2022-04-05 | Cardiovalve Ltd. | Leaflet clip with collars |
US11864995B2 (en) | 2011-08-05 | 2024-01-09 | Cardiovalve Ltd. | Implant for heart valve |
US11291547B2 (en) | 2011-08-05 | 2022-04-05 | Cardiovalve Ltd. | Leaflet clip with collars |
US11291545B2 (en) | 2011-08-05 | 2022-04-05 | Cardiovalve Ltd. | Implant for heart valve |
US11951005B2 (en) | 2011-08-05 | 2024-04-09 | Cardiovalve Ltd. | Implant for heart valve |
US10702385B2 (en) | 2011-08-05 | 2020-07-07 | Cardiovalve Ltd. | Implant for heart valve |
US10695173B2 (en) | 2011-08-05 | 2020-06-30 | Cardiovalve Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US10980650B2 (en) | 2011-10-21 | 2021-04-20 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10238514B2 (en) | 2011-10-21 | 2019-03-26 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10478295B2 (en) | 2011-10-21 | 2019-11-19 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10874508B2 (en) | 2011-10-21 | 2020-12-29 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US11707356B2 (en) | 2011-10-21 | 2023-07-25 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10537422B2 (en) | 2011-11-23 | 2020-01-21 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US11413139B2 (en) | 2011-11-23 | 2022-08-16 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US10363132B2 (en) | 2011-12-09 | 2019-07-30 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US11207175B2 (en) | 2011-12-09 | 2021-12-28 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US9757229B2 (en) | 2011-12-09 | 2017-09-12 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US11690710B2 (en) | 2011-12-09 | 2023-07-04 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US11666434B2 (en) | 2011-12-09 | 2023-06-06 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US11129710B2 (en) | 2011-12-09 | 2021-09-28 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US10307250B2 (en) | 2011-12-14 | 2019-06-04 | Edwards Lifesciences Corporation | System and method for crimping a prosthetic heart valve |
US11666436B2 (en) | 2011-12-14 | 2023-06-06 | Edwards Lifesciences Corporation | System and method for crimping a prosthetic valve |
US11497602B2 (en) | 2012-02-14 | 2022-11-15 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US10363133B2 (en) | 2012-02-14 | 2019-07-30 | Neovac Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US10016275B2 (en) | 2012-05-30 | 2018-07-10 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US11389294B2 (en) | 2012-05-30 | 2022-07-19 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US10314705B2 (en) | 2012-05-30 | 2019-06-11 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US11617650B2 (en) | 2012-05-30 | 2023-04-04 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US10940001B2 (en) | 2012-05-30 | 2021-03-09 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
EP2861186B1 (de) | 2012-06-19 | 2019-07-24 | Boston Scientific Scimed, Inc. | Herzklappenersatz |
US11622855B2 (en) | 2012-10-31 | 2023-04-11 | Medtronic Vascular Galway | Prosthetic mitral valve and delivery method |
US10537429B2 (en) | 2012-10-31 | 2020-01-21 | Medtronic Vascular Galway | Prosthetic mitral valve and delivery method |
US9744036B2 (en) | 2012-10-31 | 2017-08-29 | Medtronic Vascular Galway | Prosthetic mitral valve and delivery method |
US9023099B2 (en) | 2012-10-31 | 2015-05-05 | Medtronic Vascular Galway Limited | Prosthetic mitral valve and delivery method |
US11234819B2 (en) | 2012-11-21 | 2022-02-01 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic heart valves |
US10016276B2 (en) | 2012-11-21 | 2018-07-10 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic heart valves |
WO2014095761A1 (en) * | 2012-12-17 | 2014-06-26 | Hans Rainer Figulla | Valve prosthesis for the replacement of an atrioventicular valve |
US10034746B2 (en) | 2012-12-17 | 2018-07-31 | Hans Rainer Figulla | Valve prosthesis for the replacement of an atrioventicular valve |
EP2742911A1 (de) * | 2012-12-17 | 2014-06-18 | Hans Reiner Figulla | Klappenprothese zum Ersatz einer Atrioventricularklappe |
US10835377B2 (en) | 2013-01-24 | 2020-11-17 | Cardiovalve Ltd. | Rolled prosthetic valve support |
US10631982B2 (en) | 2013-01-24 | 2020-04-28 | Cardiovale Ltd. | Prosthetic valve and upstream support therefor |
US11844691B2 (en) | 2013-01-24 | 2023-12-19 | Cardiovalve Ltd. | Partially-covered prosthetic valves |
US9681952B2 (en) | 2013-01-24 | 2017-06-20 | Mitraltech Ltd. | Anchoring of prosthetic valve supports |
US9675452B2 (en) | 2013-02-12 | 2017-06-13 | Edwards Lifesciences Corporation | Artificial heart valve with scalloped frame design |
US9168129B2 (en) | 2013-02-12 | 2015-10-27 | Edwards Lifesciences Corporation | Artificial heart valve with scalloped frame design |
US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
US10583000B2 (en) | 2013-03-14 | 2020-03-10 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US11324591B2 (en) | 2013-03-14 | 2022-05-10 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US10716664B2 (en) | 2013-03-14 | 2020-07-21 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US9730791B2 (en) | 2013-03-14 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US11951001B2 (en) | 2013-03-14 | 2024-04-09 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grapsing intralumenal tissue and methods of delivery |
US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US11389291B2 (en) | 2013-04-04 | 2022-07-19 | Neovase Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US10383728B2 (en) | 2013-04-04 | 2019-08-20 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
EP4176841A1 (de) * | 2013-05-03 | 2023-05-10 | Cormatrix Cardiovascular, Inc. | Prothesengewebeklappen |
EP2991588A4 (de) * | 2013-05-03 | 2016-10-26 | Cormatrix Cardiovascular Inc | Prothesengewebeklappen und verfahren zur verankerung davon an kardiovaskulären strukturen |
US9867700B2 (en) | 2013-05-20 | 2018-01-16 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US10588742B2 (en) | 2013-08-14 | 2020-03-17 | Mitral Valve Technologies Sarl | Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device |
US11523899B2 (en) | 2013-08-14 | 2022-12-13 | Mitral Valve Technologies Sarl | Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device |
US11234811B2 (en) | 2013-08-14 | 2022-02-01 | Mitral Valve Technologies Sarl | Replacement heart valve systems and methods |
US10052198B2 (en) | 2013-08-14 | 2018-08-21 | Mitral Valve Technologies Sarl | Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device |
US11229515B2 (en) | 2013-08-14 | 2022-01-25 | Mitral Valve Technologies Sarl | Replacement heart valve systems and methods |
US10226330B2 (en) | 2013-08-14 | 2019-03-12 | Mitral Valve Technologies Sarl | Replacement heart valve apparatus and methods |
US11304797B2 (en) | 2013-08-14 | 2022-04-19 | Mitral Valve Technologies Sarl | Replacement heart valve methods |
US11395751B2 (en) | 2013-11-11 | 2022-07-26 | Edwards Lifesciences Cardiaq Llc | Systems and methods for manufacturing a stent frame |
US11337810B2 (en) | 2013-11-22 | 2022-05-24 | Edwards Lifesciences Corporation | Valvular insufficiency repair device and method |
US9622863B2 (en) | 2013-11-22 | 2017-04-18 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
US10507106B2 (en) | 2013-11-22 | 2019-12-17 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
US11589988B2 (en) | 2013-11-22 | 2023-02-28 | Edwards Lifesciences Corporation | Valvular insufficiency repair device and method |
US10098734B2 (en) | 2013-12-05 | 2018-10-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10595993B2 (en) | 2013-12-05 | 2020-03-24 | Edwards Lifesciences Corporation | Method of making an introducer sheath with an inner liner |
US9901444B2 (en) | 2013-12-17 | 2018-02-27 | Edwards Lifesciences Corporation | Inverted valve structure |
US11969340B2 (en) | 2014-02-18 | 2024-04-30 | Edwards Lifesciences Corporation | Flexible commissure frame |
US11432923B2 (en) | 2014-02-18 | 2022-09-06 | Edwards Lifesciences Corporation | Flexible commissure frame |
US11957574B2 (en) | 2014-02-18 | 2024-04-16 | Edwards Lifesciences Corporation | Flexible commissure frame |
US10058420B2 (en) | 2014-02-18 | 2018-08-28 | Edwards Lifesciences Corporation | Flexible commissure frame |
US10052199B2 (en) | 2014-02-21 | 2018-08-21 | Mitral Valve Technologies Sarl | Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device |
US11974914B2 (en) | 2014-02-21 | 2024-05-07 | Mitral Valve Technologies Sarl | Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device |
US10898320B2 (en) | 2014-02-21 | 2021-01-26 | Mitral Valve Technologies Sarl | Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device |
US11103345B2 (en) | 2014-05-12 | 2021-08-31 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10195025B2 (en) | 2014-05-12 | 2019-02-05 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11684471B2 (en) | 2014-06-06 | 2023-06-27 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a native mitral or tricuspid valve |
US10687939B2 (en) | 2014-06-06 | 2020-06-23 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US10010414B2 (en) | 2014-06-06 | 2018-07-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US11701225B2 (en) | 2014-07-30 | 2023-07-18 | Cardiovalve Ltd. | Delivery of a prosthetic valve |
US11872130B2 (en) | 2014-07-30 | 2024-01-16 | Cardiovalve Ltd. | Prosthetic heart valve implant |
US10492908B2 (en) | 2014-07-30 | 2019-12-03 | Cardiovalve Ltd. | Anchoring of a prosthetic valve |
US11951000B2 (en) | 2014-09-12 | 2024-04-09 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
US11406493B2 (en) | 2014-09-12 | 2022-08-09 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
US11801135B2 (en) | 2015-02-05 | 2023-10-31 | Cardiovalve Ltd. | Techniques for deployment of a prosthetic valve |
US10695177B2 (en) | 2015-02-05 | 2020-06-30 | Cardiovalve Ltd. | Prosthetic valve with aligned inner and outer frames |
US10682227B2 (en) | 2015-02-05 | 2020-06-16 | Cardiovalve Ltd. | Prosthetic valve with pivoting tissue anchor portions |
US11793638B2 (en) | 2015-02-05 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic valve with pivoting tissue anchor portions |
US11672658B2 (en) | 2015-02-05 | 2023-06-13 | Cardiovalve Ltd. | Prosthetic valve with aligned inner and outer frames |
US10390952B2 (en) | 2015-02-05 | 2019-08-27 | Cardiovalve Ltd. | Prosthetic valve with flexible tissue anchor portions |
US10888422B2 (en) | 2015-02-05 | 2021-01-12 | Cardiovalve Ltd. | Prosthetic valve with flexible tissue anchor portions |
US10426610B2 (en) | 2015-02-05 | 2019-10-01 | Cardiovalve Ltd. | Prosthetic valve with radially-deflectable tissue anchors |
US10524903B2 (en) | 2015-02-05 | 2020-01-07 | Cardiovalve Ltd. | Prosthetic valve with aligned inner and outer frames |
US11793635B2 (en) | 2015-02-05 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic valve with angularly offset frames |
US10507105B2 (en) | 2015-02-05 | 2019-12-17 | Cardiovalve Ltd. | Prosthetic valve with tissue anchors free from lateral interconnections |
US10449047B2 (en) | 2015-02-05 | 2019-10-22 | Cardiovalve Ltd. | Prosthetic heart valve with compressible frames |
US9974651B2 (en) | 2015-02-05 | 2018-05-22 | Mitral Tech Ltd. | Prosthetic valve with axially-sliding frames |
US10973636B2 (en) | 2015-02-05 | 2021-04-13 | Cardiovalve Ltd. | Prosthetic valve with tissue anchors free from lateral interconnections |
US11534298B2 (en) | 2015-02-05 | 2022-12-27 | Cardiovalve Ltd. | Prosthetic valve with s-shaped tissue anchors |
US10864078B2 (en) | 2015-02-05 | 2020-12-15 | Cardiovalve Ltd. | Prosthetic valve with separably-deployable valve body and tissue anchors |
US10667908B2 (en) | 2015-02-05 | 2020-06-02 | Cardiovalve Ltd. | Prosthetic valve with S-shaped tissue anchors |
US10722360B2 (en) | 2015-02-05 | 2020-07-28 | Cardiovalve Ltd. | Prosthetic valve with radially-deflectable tissue anchors |
US10849748B2 (en) | 2015-02-05 | 2020-12-01 | Cardiovalve Ltd. | Prosthetic valve delivery system with independently-movable capsule portions |
US10463487B2 (en) | 2015-02-05 | 2019-11-05 | Cardiovalve Ltd. | Prosthetic valve delivery system with independently-movable capsule portions |
US10918481B2 (en) | 2015-02-05 | 2021-02-16 | Cardiovalve Ltd. | Techniques for deployment of a prosthetic valve |
US10736742B2 (en) | 2015-02-05 | 2020-08-11 | Cardiovalve Ltd. | Prosthetic valve with atrial arms |
US10463488B2 (en) | 2015-02-05 | 2019-11-05 | Cardiovalve Ltd. | Prosthetic valve with separably-deployable valve body and tissue anchors |
US10357360B2 (en) | 2015-02-05 | 2019-07-23 | Cardiovalve Ltd. | Prosthetic valve with aligned inner and outer frames |
US10758344B2 (en) | 2015-02-05 | 2020-09-01 | Cardiovalve Ltd. | Prosthetic valve with angularly offset frames |
US10231834B2 (en) | 2015-02-09 | 2019-03-19 | Edwards Lifesciences Corporation | Low profile transseptal catheter and implant system for minimally invasive valve procedure |
US11963870B2 (en) | 2015-02-09 | 2024-04-23 | Edwards Lifesciences Corporation | Low profile transseptal catheter and implant system for minimally invasive valve procedure |
US11033386B2 (en) | 2015-02-09 | 2021-06-15 | Edwards Lifesciences Corporation | Low profile transseptal catheter and implant system for minimally invasive valve procedure |
US11786364B2 (en) | 2015-02-11 | 2023-10-17 | Edwards Lifesciences Corporation | Delivery apparatuses for medical device implants |
US10758341B2 (en) | 2015-02-11 | 2020-09-01 | Edwards Lifesciences Corporation | Heart valve docking devices and implanting methods |
US10039637B2 (en) | 2015-02-11 | 2018-08-07 | Edwards Lifesciences Corporation | Heart valve docking devices and implanting methods |
CN107157622A (zh) * | 2015-03-26 | 2017-09-15 | 杭州启明医疗器械有限公司 | 使用安全的瓣膜支架以及具有该瓣膜支架的瓣膜置换装置 |
EP3275404A4 (de) * | 2015-03-26 | 2018-10-31 | Venus MedTech (HangZhou), Inc. | Verwendung eines sicheren herzklappengerüsts und klappenersatzvorrichtung mit dem herzklappengerüst |
RU2703649C2 (ru) * | 2015-03-26 | 2019-10-21 | Венус Медтех (Ханчжоу), Инк. | Стент клапана и устройство для замены клапана с таким стентом |
US11406796B2 (en) | 2015-04-10 | 2022-08-09 | Edwards Lifesciences Corporation | Expandable sheath |
US10327896B2 (en) | 2015-04-10 | 2019-06-25 | Edwards Lifesciences Corporation | Expandable sheath with elastomeric cross sectional portions |
US10792471B2 (en) | 2015-04-10 | 2020-10-06 | Edwards Lifesciences Corporation | Expandable sheath |
US11850147B2 (en) | 2015-04-21 | 2023-12-26 | Edwards Lifesciences Corporation | Percutaneous mitral valve replacement device |
US10441416B2 (en) | 2015-04-21 | 2019-10-15 | Edwards Lifesciences Corporation | Percutaneous mitral valve replacement device |
US11298889B2 (en) | 2015-04-29 | 2022-04-12 | Edwards Lifesciences Corporation | Laminated sealing member for prosthetic heart valve |
US10232564B2 (en) | 2015-04-29 | 2019-03-19 | Edwards Lifesciences Corporation | Laminated sealing member for prosthetic heart valve |
US10376363B2 (en) | 2015-04-30 | 2019-08-13 | Edwards Lifesciences Cardiaq Llc | Replacement mitral valve, delivery system for replacement mitral valve and methods of use |
US11389292B2 (en) | 2015-04-30 | 2022-07-19 | Edwards Lifesciences Cardiaq Llc | Replacement mitral valve, delivery system for replacement mitral valve and methods of use |
US11083576B2 (en) | 2015-06-22 | 2021-08-10 | Edwards Lifesciences Cardiaq Llc | Actively controllable heart valve implant and method of controlling same |
US10226335B2 (en) | 2015-06-22 | 2019-03-12 | Edwards Lifesciences Cardiaq Llc | Actively controllable heart valve implant and method of controlling same |
US10842620B2 (en) | 2015-06-23 | 2020-11-24 | Edwards Lifesciences Cardiaq Llc | Systems and methods for anchoring and sealing a prosthetic heart valve |
US10092400B2 (en) | 2015-06-23 | 2018-10-09 | Edwards Lifesciences Cardiaq Llc | Systems and methods for anchoring and sealing a prosthetic heart valve |
US11844690B2 (en) | 2015-06-23 | 2023-12-19 | Edwards Lifesciences Cardiaq Llc | Systems and methods for anchoring and sealing a prosthetic heart valve |
US11051937B2 (en) | 2015-07-14 | 2021-07-06 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9974650B2 (en) | 2015-07-14 | 2018-05-22 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10758345B2 (en) | 2015-08-26 | 2020-09-01 | Edwards Lifesciences Cardiaq Llc | Replacement heart valves and methods of delivery |
US10117744B2 (en) | 2015-08-26 | 2018-11-06 | Edwards Lifesciences Cardiaq Llc | Replacement heart valves and methods of delivery |
US11253364B2 (en) | 2015-08-28 | 2022-02-22 | Edwards Lifesciences Cardiaq Llc | Steerable delivery system for replacement mitral valve and methods of use |
US10350066B2 (en) | 2015-08-28 | 2019-07-16 | Edwards Lifesciences Cardiaq Llc | Steerable delivery system for replacement mitral valve and methods of use |
US11273036B2 (en) | 2015-09-21 | 2022-03-15 | Edwards Lifesciences Corporation | Cylindrical implant and balloon |
US10314703B2 (en) | 2015-09-21 | 2019-06-11 | Edwards Lifesciences Corporation | Cylindrical implant and balloon |
US11259920B2 (en) | 2015-11-03 | 2022-03-01 | Edwards Lifesciences Corporation | Adapter for prosthesis delivery device and methods of use |
US10722354B2 (en) | 2016-02-12 | 2020-07-28 | Edwards Lifesciences Corporation | Prosthetic heart valve having multi-level sealing member |
US10179043B2 (en) | 2016-02-12 | 2019-01-15 | Edwards Lifesciences Corporation | Prosthetic heart valve having multi-level sealing member |
US11744700B2 (en) | 2016-02-12 | 2023-09-05 | Edwards Lifesciences Corporation | Prosthetic heart valve having multi-level sealing member |
US10531866B2 (en) | 2016-02-16 | 2020-01-14 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
US11937795B2 (en) | 2016-02-16 | 2024-03-26 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
US11298117B2 (en) | 2016-02-16 | 2022-04-12 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
US10517722B2 (en) | 2016-03-24 | 2019-12-31 | Edwards Lifesciences Corporation | Delivery system for prosthetic heart valve |
US11116629B2 (en) | 2016-03-24 | 2021-09-14 | Edwards Lifesciences Corporation | Delivery system for prosthetic heart valve |
USD815744S1 (en) | 2016-04-28 | 2018-04-17 | Edwards Lifesciences Cardiaq Llc | Valve frame for a delivery system |
US11224507B2 (en) | 2016-07-21 | 2022-01-18 | Edwards Lifesciences Corporation | Replacement heart valve prosthesis |
US10350062B2 (en) | 2016-07-21 | 2019-07-16 | Edwards Lifesciences Corporation | Replacement heart valve prosthesis |
US11806234B2 (en) | 2016-08-01 | 2023-11-07 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11096781B2 (en) | 2016-08-01 | 2021-08-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11872125B2 (en) | 2016-08-01 | 2024-01-16 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10856975B2 (en) | 2016-08-10 | 2020-12-08 | Cardiovalve Ltd. | Prosthetic valve with concentric frames |
USD800908S1 (en) | 2016-08-10 | 2017-10-24 | Mitraltech Ltd. | Prosthetic valve element |
US11779458B2 (en) | 2016-08-10 | 2023-10-10 | Cardiovalve Ltd. | Prosthetic valve with leaflet connectors |
US10646340B2 (en) | 2016-08-19 | 2020-05-12 | Edwards Lifesciences Corporation | Steerable delivery system for replacement mitral valve |
US11931258B2 (en) | 2016-08-19 | 2024-03-19 | Edwards Lifesciences Corporation | Steerable delivery system for replacement mitral valve and methods of use |
US11504229B2 (en) | 2016-08-26 | 2022-11-22 | Edwards Lifesciences Corporation | Multi-portion replacement heart valve prosthesis |
US10639143B2 (en) | 2016-08-26 | 2020-05-05 | Edwards Lifesciences Corporation | Multi-portion replacement heart valve prosthesis |
US10575944B2 (en) | 2016-09-22 | 2020-03-03 | Edwards Lifesciences Corporation | Prosthetic heart valve with reduced stitching |
US11273031B2 (en) | 2016-09-22 | 2022-03-15 | Edwards Lifesciences Corporation | Prosthetic heart valve with reduced stitching |
US11925550B2 (en) | 2016-09-22 | 2024-03-12 | Edwards Lifesciences Corporation | Prosthetic heart valve with reduced stitching |
US10758348B2 (en) | 2016-11-02 | 2020-09-01 | Edwards Lifesciences Corporation | Supra and sub-annular mitral valve delivery system |
US11510778B2 (en) | 2016-11-02 | 2022-11-29 | Edwards Lifesciences Corporation | Supra and sub-annular mitral valve delivery system |
US10463484B2 (en) | 2016-11-17 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic heart valve having leaflet inflow below frame |
US10973631B2 (en) | 2016-11-17 | 2021-04-13 | Edwards Lifesciences Corporation | Crimping accessory device for a prosthetic valve |
US11484406B2 (en) | 2016-11-17 | 2022-11-01 | Edwards Lifesciences Corporation | Prosthetic heart valve having leaflet inflow below frame |
US10603165B2 (en) | 2016-12-06 | 2020-03-31 | Edwards Lifesciences Corporation | Mechanically expanding heart valve and delivery apparatus therefor |
US11344408B2 (en) | 2016-12-06 | 2022-05-31 | Edwards Lifesciences Corporation | Mechanically expanding heart valve and delivery apparatus therefor |
US11654023B2 (en) | 2017-01-23 | 2023-05-23 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11938021B2 (en) | 2017-01-23 | 2024-03-26 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11185406B2 (en) | 2017-01-23 | 2021-11-30 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11013600B2 (en) | 2017-01-23 | 2021-05-25 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11135056B2 (en) | 2017-05-15 | 2021-10-05 | Edwards Lifesciences Corporation | Devices and methods of commissure formation for prosthetic heart valve |
US11026781B2 (en) | 2017-05-22 | 2021-06-08 | Edwards Lifesciences Corporation | Valve anchor and installation method |
US11883281B2 (en) | 2017-05-31 | 2024-01-30 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11717400B2 (en) | 2017-06-05 | 2023-08-08 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US10869759B2 (en) | 2017-06-05 | 2020-12-22 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US11951003B2 (en) | 2017-06-05 | 2024-04-09 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US11026785B2 (en) | 2017-06-05 | 2021-06-08 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US11883287B2 (en) | 2017-07-06 | 2024-01-30 | Edwards Lifesciences Corporation | Steerable rail delivery system |
US10813757B2 (en) | 2017-07-06 | 2020-10-27 | Edwards Lifesciences Corporation | Steerable rail delivery system |
US11123186B2 (en) | 2017-07-06 | 2021-09-21 | Edwards Lifesciences Corporation | Steerable delivery system and components |
US10918473B2 (en) | 2017-07-18 | 2021-02-16 | Edwards Lifesciences Corporation | Transcatheter heart valve storage container and crimping mechanism |
US11547544B2 (en) | 2017-07-18 | 2023-01-10 | Edwards Lifesciences Corporation | Transcatheter heart valve storage container and crimping mechanism |
US11793633B2 (en) | 2017-08-03 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic heart valve |
US11571298B2 (en) | 2017-08-03 | 2023-02-07 | Cardiovalve Ltd. | Prosthetic valve with appendages |
USD841813S1 (en) | 2017-08-03 | 2019-02-26 | Cardiovalve Ltd. | Prosthetic heart valve element |
US11246704B2 (en) | 2017-08-03 | 2022-02-15 | Cardiovalve Ltd. | Prosthetic heart valve |
USD841812S1 (en) | 2017-08-03 | 2019-02-26 | Cardiovalve Ltd. | Prosthetic heart valve element |
US10537426B2 (en) | 2017-08-03 | 2020-01-21 | Cardiovalve Ltd. | Prosthetic heart valve |
US10575948B2 (en) | 2017-08-03 | 2020-03-03 | Cardiovalve Ltd. | Prosthetic heart valve |
US11013595B2 (en) | 2017-08-11 | 2021-05-25 | Edwards Lifesciences Corporation | Sealing element for prosthetic heart valve |
US11083575B2 (en) | 2017-08-14 | 2021-08-10 | Edwards Lifesciences Corporation | Heart valve frame design with non-uniform struts |
US10932903B2 (en) | 2017-08-15 | 2021-03-02 | Edwards Lifesciences Corporation | Skirt assembly for implantable prosthetic valve |
US10898319B2 (en) | 2017-08-17 | 2021-01-26 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11969338B2 (en) | 2017-08-18 | 2024-04-30 | Edwards Lifesciences Corporation | Pericardial sealing member for prosthetic heart valve |
US11857411B2 (en) | 2017-08-18 | 2024-01-02 | Edwards Lifesciences Corporation | Pericardial sealing member for prosthetic heart valve |
US10973628B2 (en) | 2017-08-18 | 2021-04-13 | Edwards Lifesciences Corporation | Pericardial sealing member for prosthetic heart valve |
US10722353B2 (en) | 2017-08-21 | 2020-07-28 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11850148B2 (en) | 2017-08-21 | 2023-12-26 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10973629B2 (en) | 2017-09-06 | 2021-04-13 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11147667B2 (en) | 2017-09-08 | 2021-10-19 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10888421B2 (en) | 2017-09-19 | 2021-01-12 | Cardiovalve Ltd. | Prosthetic heart valve with pouch |
US11872131B2 (en) | 2017-12-13 | 2024-01-16 | Cardiovalve Ltd. | Prosthetic valve and delivery tool therefor |
US11382746B2 (en) | 2017-12-13 | 2022-07-12 | Cardiovalve Ltd. | Prosthetic valve and delivery tool therefor |
US11872124B2 (en) | 2018-01-10 | 2024-01-16 | Cardiovalve Ltd. | Temperature-control during crimping of an implant |
US11633277B2 (en) | 2018-01-10 | 2023-04-25 | Cardiovalve Ltd. | Temperature-control during crimping of an implant |
US11051934B2 (en) | 2018-02-28 | 2021-07-06 | Edwards Lifesciences Corporation | Prosthetic mitral valve with improved anchors and seal |
US11318011B2 (en) | 2018-04-27 | 2022-05-03 | Edwards Lifesciences Corporation | Mechanically expandable heart valve with leaflet clamps |
US11446141B2 (en) | 2018-10-19 | 2022-09-20 | Edwards Lifesciences Corporation | Prosthetic heart valve having non-cylindrical frame |
US11723783B2 (en) | 2019-01-23 | 2023-08-15 | Neovasc Medical Ltd. | Covered flow modifying apparatus |
US11399932B2 (en) | 2019-03-26 | 2022-08-02 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11779742B2 (en) | 2019-05-20 | 2023-10-10 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
US11963871B2 (en) | 2020-06-18 | 2024-04-23 | Edwards Lifesciences Corporation | Crimping devices and methods |
Also Published As
Publication number | Publication date |
---|---|
US10456248B2 (en) | 2019-10-29 |
ES2445589T3 (es) | 2014-03-04 |
DE202008018458U1 (de) | 2014-02-28 |
US20120035703A1 (en) | 2012-02-09 |
DE102007043830A1 (de) | 2009-04-02 |
US20140364944A1 (en) | 2014-12-11 |
US20120035713A1 (en) | 2012-02-09 |
US9254192B2 (en) | 2016-02-09 |
DE202008018461U1 (de) | 2014-02-12 |
US9078749B2 (en) | 2015-07-14 |
DE202008018459U1 (de) | 2014-02-07 |
EP2194925A1 (de) | 2010-06-16 |
US20150305868A1 (en) | 2015-10-29 |
US20170312076A1 (en) | 2017-11-02 |
US9730792B2 (en) | 2017-08-15 |
US20200000583A1 (en) | 2020-01-02 |
US11213387B2 (en) | 2022-01-04 |
US20160151155A1 (en) | 2016-06-02 |
US20120283824A1 (en) | 2012-11-08 |
US9095433B2 (en) | 2015-08-04 |
US20110004296A1 (en) | 2011-01-06 |
DE202008018470U1 (de) | 2014-02-27 |
US20220039947A1 (en) | 2022-02-10 |
EP2194925B1 (de) | 2013-11-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2194925B1 (de) | Herzklappenstent | |
DE102006052564B3 (de) | Mitralklappenstent | |
DE102018100321B9 (de) | Herzklappenreparatursystem | |
DE102018010279B9 (de) | Klappenreparaturvorrichtung | |
DE102018100319B4 (de) | Reparaturvorrichtungen und -verfahren für körpereigene Klappen | |
DE102018100350B9 (de) | Reparaturvorrichtungen und -verfahren für körpereigene klappen | |
DE102018100325B4 (de) | Reparaturvorrichtungen und -verfahren für körpereigene Klappen | |
DE102018100322B4 (de) | Reparaturvorrichtungen und -systeme für körpereigene Klappen | |
DE102018100323B9 (de) | Klappenreparatursystem | |
DE102018100347B4 (de) | Reparaturvorrichtungen und -verfahren für körpereigene klappen | |
DE102018100352B9 (de) | Klappenreparatursystem |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 08801319 Country of ref document: EP Kind code of ref document: A1 |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2008801319 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 12677958 Country of ref document: US |