UY27904A1 - Monoetanosulfonato de 3-z-(1-(4-(n-((4-metil-piperazina-1-il)-metilcarbonil)-n-metil-amino)-anilino)-1-fenil-metilen)-6-metoxicarbonil-2-indolinona y su utilización como medicamento - Google Patents

Monoetanosulfonato de 3-z-(1-(4-(n-((4-metil-piperazina-1-il)-metilcarbonil)-n-metil-amino)-anilino)-1-fenil-metilen)-6-metoxicarbonil-2-indolinona y su utilización como medicamento

Info

Publication number
UY27904A1
UY27904A1 UY27904A UY27904A UY27904A1 UY 27904 A1 UY27904 A1 UY 27904A1 UY 27904 A UY27904 A UY 27904A UY 27904 A UY27904 A UY 27904A UY 27904 A1 UY27904 A1 UY 27904A1
Authority
UY
Uruguay
Prior art keywords
methyl
indolinone
phenyl
amino
monoethanosulfonate
Prior art date
Application number
UY27904A
Other languages
English (en)
Inventor
Dr Gerald Jurgen Roth
Dr Gunter Linz
Dr Peter Sieger
Werner Rall
Dr Frank Hilberg
Dr Thomas Bock
Original Assignee
Boehringer Ingelheim Pharma
Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30469050&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY27904(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma, Co Kg filed Critical Boehringer Ingelheim Pharma
Publication of UY27904A1 publication Critical patent/UY27904A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Objeto del presente invento es el compuesto monoetanosulfonato de 3-Z-(1-(4-(N-((4-metil-piperazina-1-il)-metilcarbonil)-N-metil-amino)-1-fenil-metilen)-6-metoxicarbonil-2-indolinona de la fórmula I y su utilización como medicamento.
UY27904A 2002-07-24 2003-07-23 Monoetanosulfonato de 3-z-(1-(4-(n-((4-metil-piperazina-1-il)-metilcarbonil)-n-metil-amino)-anilino)-1-fenil-metilen)-6-metoxicarbonil-2-indolinona y su utilización como medicamento UY27904A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10233500A DE10233500A1 (de) 2002-07-24 2002-07-24 3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
UY27904A1 true UY27904A1 (es) 2004-02-27

Family

ID=30469050

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27904A UY27904A1 (es) 2002-07-24 2003-07-23 Monoetanosulfonato de 3-z-(1-(4-(n-((4-metil-piperazina-1-il)-metilcarbonil)-n-metil-amino)-anilino)-1-fenil-metilen)-6-metoxicarbonil-2-indolinona y su utilización como medicamento

Country Status (36)

Country Link
US (2) US7119093B2 (es)
EP (2) EP2386543A1 (es)
JP (1) JP5039279B2 (es)
KR (1) KR101145691B1 (es)
CN (1) CN100351235C (es)
AR (2) AR040662A1 (es)
AT (1) ATE551322T1 (es)
AU (1) AU2003254376B2 (es)
BR (1) BRPI0312811B8 (es)
CA (1) CA2493310C (es)
CY (1) CY1112916T1 (es)
DE (1) DE10233500A1 (es)
DK (1) DK1527047T3 (es)
EA (1) EA008684B1 (es)
EC (1) ECSP055571A (es)
EG (1) EG24562A (es)
ES (1) ES2384968T3 (es)
HK (1) HK1078851A1 (es)
HR (1) HRP20050070B1 (es)
IL (2) IL166405A0 (es)
ME (1) ME00353B (es)
MX (1) MXPA04012785A (es)
MY (1) MY136883A (es)
NO (1) NO330486B1 (es)
NZ (1) NZ538367A (es)
PE (1) PE20040704A1 (es)
PL (1) PL223758B1 (es)
PT (1) PT1527047E (es)
RS (1) RS52283B (es)
SA (1) SA03240446B1 (es)
SI (1) SI1527047T1 (es)
TW (1) TWI285635B (es)
UA (1) UA78352C2 (es)
UY (1) UY27904A1 (es)
WO (1) WO2004013099A1 (es)
ZA (1) ZA200409814B (es)

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Publication number Publication date
PE20040704A1 (es) 2004-11-29
ATE551322T1 (de) 2012-04-15
NO330486B1 (no) 2011-04-26
DE10233500A1 (de) 2004-02-19
AU2003254376B2 (en) 2010-06-17
CA2493310C (en) 2011-01-18
PT1527047E (pt) 2012-06-28
CY1112916T1 (el) 2016-04-13
NZ538367A (en) 2008-01-31
KR20050042139A (ko) 2005-05-04
US7119093B2 (en) 2006-10-10
KR101145691B1 (ko) 2012-05-25
RS52283B (sr) 2012-10-31
HRP20050070A2 (en) 2005-12-31
EP1527047B1 (en) 2012-03-28
JP2005535684A (ja) 2005-11-24
DK1527047T3 (da) 2012-07-16
SA03240446B1 (ar) 2007-07-31
EG24562A (en) 2009-10-25
NO20050985L (no) 2005-02-23
BRPI0312811B1 (pt) 2019-03-12
AR094217A2 (es) 2015-07-15
IL166405A0 (en) 2006-01-15
BR0312811A (pt) 2005-04-19
CA2493310A1 (en) 2004-02-12
PL372996A1 (en) 2005-08-08
MY136883A (en) 2008-11-28
EA200500146A1 (ru) 2005-08-25
ZA200409814B (en) 2006-02-22
AR040662A1 (es) 2005-04-13
MXPA04012785A (es) 2005-06-08
BRPI0312811B8 (pt) 2021-05-25
PL223758B1 (pl) 2016-10-31
ME00353B (me) 2011-10-10
WO2004013099A1 (en) 2004-02-12
TWI285635B (en) 2007-08-21
MEP53708A (en) 2011-05-10
US20040176392A1 (en) 2004-09-09
JP5039279B2 (ja) 2012-10-03
EA008684B1 (ru) 2007-06-29
RS20050046A (en) 2007-09-21
HRP20050070B1 (hr) 2013-09-30
EP1527047A1 (en) 2005-05-04
CN1671660A (zh) 2005-09-21
ES2384968T3 (es) 2012-07-16
HK1078851A1 (en) 2006-03-24
SI1527047T1 (sl) 2012-07-31
IL166405A (en) 2009-11-18
AU2003254376A1 (en) 2004-02-23
ECSP055571A (es) 2005-04-18
CN100351235C (zh) 2007-11-28
TW200409754A (en) 2004-06-16
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