US20050112259A1 - Pet food composition having enhanced palatability - Google Patents

Pet food composition having enhanced palatability Download PDF

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Publication number
US20050112259A1
US20050112259A1 US10/996,713 US99671304A US2005112259A1 US 20050112259 A1 US20050112259 A1 US 20050112259A1 US 99671304 A US99671304 A US 99671304A US 2005112259 A1 US2005112259 A1 US 2005112259A1
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Prior art keywords
food composition
extract
food
oregano
composition
Prior art date
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Abandoned
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US10/996,713
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English (en)
Inventor
Fernando Qvyjt
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Hills Pet Nutrition Inc
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Hills Pet Nutrition Inc
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Application filed by Hills Pet Nutrition Inc filed Critical Hills Pet Nutrition Inc
Priority to US10/996,713 priority Critical patent/US20050112259A1/en
Assigned to HILL'S PET NUTRITION, INC. reassignment HILL'S PET NUTRITION, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: QVYJT, FERNANDO
Publication of US20050112259A1 publication Critical patent/US20050112259A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A23K50/42Dry feed
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

Definitions

  • the present invention relates to pet food compositions having enhanced palatability and to methods of enhancing palatability of a pet food.
  • Cats in particular are notoriously finicky, fastidious or otherwise excessively selective in what they will eat.
  • Enticing a companion animal to eat can be an expensive and time consuming chore. Foods with varying moisture content, supplements and treats have been developed to encourage animals to eat, however these attempts are an imperfect solution to the problem.
  • U.S. Patent Application Publication No. 2003/019343 discloses use of a mixture of natural herbs and spices as a palatability improving agent.
  • natural herbs and spices for use in such a mixture include allspice, anise, basil, bay, black pepper, caraway, cardamom, cassia, celery seed, cinnamon, clover, coriander, cumin, dill, fennel, ginger, marjoram, mustard, nutmeg, oregano, paprika, rosemary, saffron, sage, savory, tarragon, thyme, turmeric and white pepper.
  • U.S. Pat. No. 4,514,431 discloses meat-flavored products including cat and dog foods.
  • a recipe is given for a ground sausage mixture containing, inter alia, oils of black pepper, celery, cloves, coriander, cumin, ginger, mustard, nutmeg and pimenta berries, as well as oleoresin capsicum.
  • European Patent No. 1 063 897 discloses a dual texture pet or animal food that can comprise ingredients such as rosemary, clove and parsley seed oils.
  • U.S. Pat. No. 6,156,355 discloses various pet food formulations that comprise certain extracts or oils of herbs and spices, including for example rosemary extract, Yucca schidigera extract, parsley seed oil powder and ginger extract.
  • U.S. Pat. No. 6,106,838 discloses a pharmaceutical composition comprising an essential oil that comprises thymol and carvacrol, for example an essential oil of Origanum species, reportedly useful as an antimicrobial.
  • This invention is directed to animal foods having enhanced palatability and to methods for enhancing palatability of animal foods. It is contemplated that such compositions and methods can be useful in relation to a wide range of non-human animals, but more particularly companion animals such as cats and dogs.
  • a food composition for a companion animal comprising an extract of a herb or spice that comprises at least one compound having the formula as a substantial flavorant ingredient.
  • the extract is present in the food composition in an amount equivalent, in content of compounds of the above formula, to at least about 1 ppm by weight of essential oil of oregano.
  • a food composition for a companion animal comprising an extract of a herb or spice of the botanical family Verbenaceae, said extract being present in the food composition in an amount equivalent, in flavorant effect, to at least about 1 ppm by weight of essential oil of oregano.
  • a method for enhancing palatability of a food composition to a companion animal comprising adding to the composition a palatability enhancing effective amount of an extract of a herb or spice that comprises at least one compound having the formula as a substantial flavorant ingredient.
  • the extract is added to the food composition in an amount equivalent, in content of compounds of the above formula, to at least about 1 ppm by weight of essential oil of oregano.
  • a method for enhancing palatability of a food composition to a companion animal comprising adding to the composition a palatability enhancing effective amount of an extract of a herb or spice of the botanical family Verbenaceae (herein a “verbenaceous extract”).
  • the extract is added to the food composition in an amount equivalent, in flavorant effect, to at least about 1 ppm by weight of essential oil of oregano.
  • any verbenaceous extract, or any herb or spice extract that comprises thymol and/or carvacrol in a substantial flavorant amount can be substituted, including but not limited to essential oils, oleoresins, infusions, tinctures and natural extractives, including distillates.
  • a pet food composition comprising an extract as defined herein can exhibit surprisingly high palatability to a companion animal; furthermore practice of the method as described herein can impart surprisingly high palatability to a pet food that otherwise is of inferior palatability to a companion animal.
  • Extract herein is a preparation made from any part or parts of a herb or spice that comprises, generally in concentrated form, compounds that contribute to the characteristic flavor and/or aroma of the herb or spice. Extracts include without limitation essential oils, oleoresins, infusions, tinctures and natural extractives, including distillates. Extracts do not include crude plant parts, whether whole or ground. It is contemplated that considerable advantages are obtainable by use of an extract as provided herein, rather than by use of the corresponding herb or spice in crude form as proposed, for example, in above-cited U.S. Patent Application Publication No. 2003/019343. Such advantages can include greater standardization and/or uniformity of flavorant effect, lower cost, improved cost stability, greater ease of processing, etc.
  • a “flavorant” compound or ingredient herein is a compound or ingredient that, when it occurs naturally in a plant part, contributes to the characteristic flavor and/or aroma of the plant part, and/or, when extracted from a plant or synthesized, has a distinctive flavor that it imparts to a composition comprising that compound or ingredient.
  • a “substantial flavorant ingredient” of a herb or spice or an extract thereof is a flavorant ingredient present in sufficient amount to have an organoleptically detectable effect on the flavor and/or aroma of the herb or spice or extract thereof. Typically, such an ingredient is present in an amount of at least about 1%, more typically at least about 5%, by weight of an essential oil of the herb or spice.
  • Essential oil of oregano which can contain up to 70% by weight or more of thymol and carvacrol, is the standard herein. Where essential oil of oregano is used in a food composition, the amount used should be at least about 1 ppm by weight. Where a herb or spice extract other than essential oil of oregano is used, the amount used should be an amount equivalent to 1 ppm of essential oil of oregano, in content of thymol and carvacrol or in palatant effect. An essential oil of oregano equivalent amount of any such extract can readily be determined by one of ordinary skill in the art based on the disclosure herein.
  • oregano is a general term applying to a herb having a particular flavor, rather than to a particular species of plant. See Fenaroli's Handbook of Flavor Ingredients, Vol. 1,3rd ed. (1995), CRC Press, at p. 210. Accordingly, essential oil or other extract of oregano for the purposes of the present invention can be derived from any oregano-flavored herb, including Lippia graveolens of the family Verbenaceae (also known as Mexican oregano), Origanum species including O. vulgare (also known as wild marjoram), O. viride and O. virens, Coleus ambionica and Thymus martichina of the family Labiatae.
  • the food composition comprises an oil of oregano equivalent amount of at least about 1 ppm of a herb or spice extract comprising at least one of thymol and carvacrol.
  • the extract comprises thymol. In another embodiment the extract comprises carvacrol.
  • Both thymol and carvacrol can be present, at any weight ratio, for example a weight ratio of about 1:10 to about 10:1.
  • Such an extract can be derived from an oregano-flavored herb as described above, or from any other thymol- and/or carvacrol-containing herb or spice.
  • Non-limiting examples of such herbs or spices other than those listed above include basil ( Ocimum species, particularly O. gratissimum ); dittany of Crete, also known as Spanish hops ( Origanum dictamnus ); horsemint, also known as wild bergamot ( Monarda punctata ), and other Monarda species; savory ( Satureia species including S. hortensis and S. montana ); thyme (Thymus species including T. vulgare, T. serpyllum, T. zygis and T. capitatus ); and the fruits of Schinus molle.
  • Illustrative examples of extracts useful according to this embodiment include the essential oils of oregano and thyme.
  • the food composition comprises an oil of oregano equivalent amount of at least about 1 ppm of a verbenaceous extract such as those obtained from Lippia species such as L. graveolens (Mexican oregano) or L. citriodora (lemon verbena), or from Verbena officinalis (vervain).
  • a verbenaceous extract such as those obtained from Lippia species such as L. graveolens (Mexican oregano) or L. citriodora (lemon verbena), or from Verbena officinalis (vervain).
  • the food composition comprises an extract, for example an essential oil, of a herb or spice selected from the group consisting of anise, arnica, basil, bergamot, calendula, caraway, chamomile, cinnamon, citrus (including lemon), elder, eucalyptus, fir needle, garlic, hops, juniper, lavender, lemon balm, licorice, marjoram, oregano, passionflower, peppermint, primrose, thyme and vanilla. More particularly, the extract is derived from cinnamon, citrus (including lemon), eucalyptus, lavender, oregano, peppermint, thyme or vanilla. Compositions of this embodiment, when fed to companion animals, can be beneficial in reducing odor of excreta, including stool odor and flatulence odor.
  • an extract for example an essential oil, of a herb or spice selected from the group consisting of anise, arnica, basil, bergamot, calendula, caraway, chamomile, cinnamon, citrus (
  • Contemplated food compositions include, for example, canned moist pet foods, extruded dry pet foods, supplements and treats. All are adapted for consumption by a companion animal such as a dog or cat, but are not necessarily suitable for human consumption. In one embodiment the food composition, by virtue of the quality or origin of the ingredients or means of processing, is not adapted for human consumption. Any pet food can benefit from inclusion of a herb or spice extract as defined herein, but in one embodiment the pet food is one having a major (at least about 25%, for example at least about 50%, by weight) component derived from animal (e.g., mammal, bird or fish) proteinaceous tissues including muscle tissues and offal, optionally with a carbohydrate source such as cereal grains.
  • animal e.g., mammal, bird or fish
  • the herb or spice extract can be distributed more or less homogeneously through the food composition.
  • the herb or spice extract can be present in whole or in part on surfaces of food pieces such as meat chunks, dry kibbles or individual treats such as dog biscuits.
  • the herb or spice extract should be present in an amount that is not toxic or otherwise deleterious to the health of a companion animal consuming a normal quantity of the food composition.
  • the extract should be present at a concentration that does not cause undesirable effects on digestion, particularly long-term effects lasting several days or longer. Undesirable effects on digestion can include, for example, constipation or diarrhea.
  • Suitable amounts of a herb or spice extract as provided herein will normally be found in a range of about 1 to about 1000 ppm, for example about 5 to about 100 ppm, or about 10 to about 50 ppm, expressed as essential oil of oregano equivalent. Where the extract is localized on surfaces of food pieces, local concentrations can exceed those suggested here, but the overall concentration in the food composition as a whole will generally be in a range as stated above.
  • the components of the food composition are adjusted so that the herb or spice extract is present in the composition at a desired concentration.
  • the herb or spice extract can, for example, be incorporated into the food composition during formulation, such as during and/or after mixing of other components of the composition. Distribution of these components into the composition can be accomplished by any conventional method including standard mixing procedures.
  • Food compositions of the present invention can be prepared in a wet or containerized (e.g., canned) form using conventional pet food processes.
  • ground animal e.g., mammal, poultry and/or fish
  • proteinaceous tissues are mixed with other ingredients, including for example animal fats and vegetable oils, cereal grains, other nutritionally balancing ingredients, special purpose additives (e.g., vitamin and mineral mixtures, inorganic salts, cellulose and beet pulp, bulking agents, and the like); and water sufficient for processing is also added.
  • These ingredients typically are mixed in a vessel suitable for heating while blending the components. Heating of the mixture can be effected in any suitable manner, such as, for example, by direct steam injection or by using a vessel fitted with a heat exchanger.
  • the mixture is heated in a pre-cooking step to a temperature of up to about 100° C. Higher temperatures can be acceptable, but can be commercially impractical without use of other processing aids.
  • the material is typically in the form of a thick liquid.
  • the thick liquid is filled into suitable containers such as cans, jars, pouches or the like.
  • a lid is applied, and the container is hermetically sealed.
  • the sealed containers are then placed into conventional equipment designed to sterilize the contents. This is usually accomplished by heating to a temperature of at least about 110° C. for an appropriate time, which is dependent on, for example, the temperature used and the composition.
  • Products can also be prepared by an aseptic process wherein the contents are heated to commercial sterility before being packaged in sterilized containers.
  • the herb or spice extract can be added to containerized pet food products before, during or after the pre-cooking step.
  • Food compositions of the present invention can be prepared in a dry form using conventional processes.
  • dry ingredients including, for example, animal protein sources, plant protein sources, grains, etc.
  • Moist or liquid ingredients including fats, oils, animal protein sources, water, etc.
  • the mixture is then processed into kibbles or similar dry pieces. Kibble is often formed using an extrusion process in which the mixture of dry and wet ingredients is subjected to mechanical work at a high pressure and temperature, and forced through small openings and cut off into kibble by a rotating knife.
  • Kibble also can be made from the dough using a baking process, rather than extrusion, wherein the dough is placed into a mold before dry-heat processing. Kibble also can be made from a food matrix undergoing pelletization.
  • the herb or spice extract can be incorporated into the food composition by addition to the above-described mixtures before extrusion or by coating extruded kibble or pellets with the herb or spice extract as an ingredient of a topical coating.
  • an essential oil can be added to liquids in a dry processing line, to a pre-conditioner composition or to a coating composition.
  • the food composition is a nutritional supplement comprising a herb or spice extract as defined herein.
  • Supplements include, for example, a pet food used with another pet food to improve the nutritive balance or performance of the total.
  • Contemplated supplements include compositions that are fed undiluted as a supplement to other pet foods, offered free choice with other parts of an animal's ration that are separately available, or diluted and mixed with an animal's regular food to produce a complete diet.
  • the AAFCO for example, provides a discussion relating to supplements in the American Feed Control Officials, Inc. Official Publication (2003), at p. 220.
  • Supplements can be in various forms including, for example, powders, liquids, syrups, pills, encapsulated compositions, etc.
  • the composition is a dog or cat treat comprising the herb or spice extract.
  • Treats include, for example, compositions that are given to an animal to entice the animal to eat during a non-meal time.
  • Contemplated treats for canines include dog biscuits, for example in the shape of dog bones.
  • Treats can be nutritional, wherein the composition comprises one or more nutrients, and can, for example, have a composition as described above for a pet food.
  • Non-nutritional treats encompass any other treats that are non-toxic.
  • the herb or spice extract can be present in a coating on the surface of the treat, or incorporated into the treat, or both.
  • a herb or spice extract can, if desired, be encapsulated in pet food systems.
  • a herb or spice extract can be added to a palatant (such as a digest or broth) at any time during processing of the palatant.
  • a further embodiment of the invention is a method for enhancing the palatability to a companion animal of a food composition, the method comprising adding to the food composition a palatability enhancing effective amount of a herb or spice extract as described hereinabove.
  • Palatability enhancement can be measured by any procedure known in the art, but in an illustrative procedure enhanced palatability can be quantified by determining an intake ratio in a palatability test.
  • a test formulation for example a food composition of the present invention
  • a control or comparator formulation for example a food composition lacking a herb or spice extract as described herein
  • a suitable duration is about 45 minutes for a dog or 24 hours for a cat, but this can be varied if desired.
  • the weight ratio of test food consumed to total food (test food plus control food) consumed during that period is a measure of intake ratio and of relative palatability of the two foods.
  • An intake ratio substantially greater than about 0.5 is indicative of enhanced palatability.
  • the herb or spice extract can be added during manufacturing of the food composition, for example by a process of mixing or coating as indicated above.
  • the herb or spice extract is added to a companion animal's food by the person responsible for feeding the companion animal.
  • the herb or spice extract can be used as such, for example as an undiluted essential oil.
  • a suitable carrier such as vegetable oil or edible powder.
  • a powder comprising the herb or spice extract can be sprinkled on an animal's food immediately before feeding.
  • a liquid comprising the herb or spice extract can be sprayed on the food.
  • Such powder or liquid compositions are described herein as “palatability enhancer compositions” and can be thought of as “seasonings”. They can be applied to the top of a serving of pet food and/or can, if desired, be mixed into the food.
  • the use of palatability enhancer compositions or seasonings comprising a herb or spice extract as specified herein to enhance palatability of a pet food composition is an embodiment of the present invention.
  • a palatability enhancer composition or seasoning as described above can be purchased by a pet owner independently of the pet food to which it is to be added; alternatively, such a palatability enhancer composition or seasoning can be purchased together with the pet food in the form of a kit, for example a co-packaged kit.
  • a kit can further include a label or package insert providing guidance or instructions as to suitable amounts of the seasoning to be added to the food composition.
  • a palatability enhancing effective amount of the herb or spice extract will generally be found in a range as provided above, for example about 1 to about 1000 ppm, or about 5 to about 100 ppm, or about 10 to about 50 ppm, by weight of the food composition to which the herb or spice extract is to be added.
  • a method for enhancing palatability of a food composition to a companion animal comprising adding to the composition a palatability enhancing effective amount of at least one compound having the formula
  • the at least one compound of the above formula can be thymol or carvacrol.
  • both thymol and carvacrol can be added according to the method of the invention.
  • the compound of the above formula can be of natural or synthetic origin.
  • the at least one compound of the above formula can be added to the food composition in any palatability enhancing effective amount that is not toxic or otherwise deleterious to the health of the animal, for example an amount of about 1 to about 1000 ppm, or about 5 to about 100 ppm, or about 10 to about 50 ppm, by weight of the food composition.
  • non-human animals such as non-human primates (e.g., monkeys, chimpanzees, etc.), companion animals (e.g., dogs, cats, horses, etc.), farm animals (e.g., goats, sheep, swine, cattle, etc.), laboratory animals (e.g., mice, rats, etc.), birds (e.g., domestic birds such as canaries, parrots, etc.
  • non-human primates e.g., monkeys, chimpanzees, etc.
  • companion animals e.g., dogs, cats, horses, etc.
  • farm animals e.g., goats, sheep, swine, cattle, etc.
  • laboratory animals e.g., mice, rats, etc.
  • birds e.g., domestic birds such as canaries, parrots, etc.
  • rodents e.g., hamsters, guinea pigs, gerbils, rabbits, hedgehogs, ferrets, chinchillas, etc.
  • wild, exotic and zoo animals e.g., wolves, bears, deer, etc.
  • the animal is a cat.
  • the animal is a dog.
  • the method of the invention will be found especially beneficial in cases where the animal is, or has become, finicky, has poor appetite, or is in ill health, all of which can occur in animals of all ages but especially in aged animals.
  • the method will also be found especially beneficial where the food composition is one to which the animal is unaccustomed, or contains ingredients or a balance of ingredients designed to improve health or wellness with less emphasis on palatability.
  • Dry pet food and containerized pet food products were prepared from existing formulas with the additional inclusion of essential oil of oregano.
  • Table 1 shows results of a palatability study in 25 cats offered test foods that were dry cat foods prepared with and without addition of essential oil of oregano to the pre-conditioner composition during preparation of the foods. Two control foods were provided.
  • An intake ratio defined as the average ratio of test food ingested to total food ingested, was determined for each test food in comparison with each of the two control foods.
  • Each animal received a pre-weighed food dish containing the test food and, simultaneously, a pre-weighed food dish containing the control food.

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Inorganic Chemistry (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Housing For Livestock And Birds (AREA)
  • Medicinal Preparation (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Feeding And Watering For Cattle Raising And Animal Husbandry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Processing Of Solid Wastes (AREA)
US10/996,713 2003-11-26 2004-11-24 Pet food composition having enhanced palatability Abandoned US20050112259A1 (en)

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EP (2) EP1694137B1 (ru)
JP (3) JP5506138B2 (ru)
CN (3) CN1886061B (ru)
AT (2) ATE418271T1 (ru)
AU (2) AU2004294958B2 (ru)
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DE (1) DE602004018680D1 (ru)
DK (2) DK1694137T3 (ru)
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Cited By (30)

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US20050249837A1 (en) * 2004-05-10 2005-11-10 The Procter & Gamble Company Processes for preparing plant matter extracts and pet food compositions
US20050249841A1 (en) * 2001-09-12 2005-11-10 The Procter & Gamble Company Pet food compositions
US20080032021A1 (en) * 2006-05-19 2008-02-07 Faltys Gary L Feed supplements for ruminants including essential oil compounds and organic acids
FR2911251A1 (fr) * 2007-01-12 2008-07-18 Pancosma Sa Pour L Ind Des Pro Aliment tracable par molecules aromatiques
US20080214479A1 (en) * 1997-07-08 2008-09-04 The Lams Company Methods of mimicking the metabolic effects of caloric restriction by administration of mannoheptulose
US20080260696A1 (en) * 2007-02-01 2008-10-23 Stefan Patrick Massimino Method for decreasing inflammation and oxidative stress in mammals
US20080260866A1 (en) * 2004-05-10 2008-10-23 Stefan Patrick Massimino Method for decreasing inflammation and stress in a mammal
US20090042984A1 (en) * 2007-08-06 2009-02-12 Tien Linsheng W Cool-Pet System
US20090252834A1 (en) * 2004-05-10 2009-10-08 Michael Griffin Hayek Compositions comprising glucose anti-metabolites
US20090253642A1 (en) * 1997-07-08 2009-10-08 Josef Pitha Mimicking the metabolic effects of caloric restriction by administration of glucose anti-metabolites
US20090263542A1 (en) * 2005-05-13 2009-10-22 Charlie Hungwei Lin Dry Food Compositions Having Enhanced Palatability
US20110206809A1 (en) * 2010-02-22 2011-08-25 Jeff Tate Compositions and methods for making animal feeds having shapes of natural food sources
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BRPI0416881A (pt) 2007-02-06
EP1694136B1 (en) 2011-12-21
EP1694136A2 (en) 2006-08-30
AU2004294986B2 (en) 2010-09-09
US20050112217A1 (en) 2005-05-26
CA2546286A1 (en) 2005-06-16
WO2005053420A3 (en) 2005-08-04
ATE418271T1 (de) 2009-01-15
JP2012095661A (ja) 2012-05-24
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CN1886061A (zh) 2006-12-27
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CA2546283A1 (en) 2005-06-16
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