UA83200C2 - 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES - Google Patents

2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES

Info

Publication number
UA83200C2
UA83200C2 UAA200504391A UA2005004391A UA83200C2 UA 83200 C2 UA83200 C2 UA 83200C2 UA A200504391 A UAA200504391 A UA A200504391A UA 2005004391 A UA2005004391 A UA 2005004391A UA 83200 C2 UA83200 C2 UA 83200C2
Authority
UA
Ukraine
Prior art keywords
ris
nitroimidazo
dihydro
oxazoles
calkyl
Prior art date
Application number
UAA200504391A
Other languages
English (en)
Russian (ru)
Inventor
Хидецугу Цубоучи
Хирофуми Сасаки
Хидеаки Курода
Мотохиро ИТОТАНИ
Такеси ХАСЕГАВА
Йосикадзу Харагути
Такеси КУРОДА
Такаюки Мацудзаки
Кунинори Таи
Макото Коматсу
Макото МАЦУМОТО
Хироюки ХАСИЗУМЕ
Тацуо ТОМИСИГЕ
Юдзи Сейке
Масанори КАВАСАКИ
Такуми Сумида
Син МИЯМУРА
Original Assignee
Оцука Фармасьютикел Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Оцука Фармасьютикел Ко., Лтд. filed Critical Оцука Фармасьютикел Ко., Лтд.
Publication of UA83200C2 publication Critical patent/UA83200C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
UAA200504391A 2002-10-11 2003-10-10 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES UA83200C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002298259 2002-10-11
PCT/JP2003/013070 WO2004033463A1 (ja) 2002-10-11 2003-10-10 ２，３−ジヒドロ−６−ニトロイミダゾ[２，１−ｂ]オキサゾール化合物

Publications (1)

Publication Number Publication Date
UA83200C2 true UA83200C2 (en) 2008-06-25

Family

ID=32089299

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200504391A UA83200C2 (en) 2002-10-11 2003-10-10 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES

Country Status (26)

Country Link
US (1) US7262212B2 (Direct)
EP (2) EP1555267B1 (Direct)
JP (1) JP4186065B2 (Direct)
KR (1) KR100723847B1 (Direct)
CN (4) CN101172981A (Direct)
AR (4) AR041198A1 (Direct)
AU (1) AU2003272979B2 (Direct)
BE (1) BE2014C053I2 (Direct)
BR (1) BRPI0314344B8 (Direct)
CA (1) CA2497569C (Direct)
CY (2) CY1113578T1 (Direct)
DK (1) DK1555267T3 (Direct)
ES (1) ES2400179T3 (Direct)
FR (1) FR14C0066I2 (Direct)
HU (1) HUS1400046I1 (Direct)
LU (1) LU92517I2 (Direct)
MX (1) MXPA05003674A (Direct)
MY (1) MY139244A (Direct)
PL (3) PL217919B1 (Direct)
PT (1) PT1555267E (Direct)
RU (1) RU2326121C3 (Direct)
SI (1) SI1555267T1 (Direct)
TW (1) TWI347946B (Direct)
UA (1) UA83200C2 (Direct)
WO (1) WO2004033463A1 (Direct)
ZA (1) ZA200501033B (Direct)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4564713B2 (ja) 2000-11-01 2010-10-20 ミレニアム・ファーマシューティカルズ・インコーポレイテッド 窒素性複素環式化合物、ならびに窒素性複素環式化合物およびその中間体を作製するための方法
MY145079A (en) 2002-10-15 2011-12-15 Otsuka Pharma Co Ltd 1-substituted-4-nitroimidazole compound and method for preparing the same
JP4761756B2 (ja) * 2003-10-31 2011-08-31 大塚製薬株式会社 ２，３−ジヒドロイミダゾ［２，１−ｂ］オキサゾ−ル化合物
TWI335331B (en) * 2003-10-31 2011-01-01 Otsuka Pharma Co Ltd 2,3-dihydro-6-nitroimidazo [2,1-b] oxazole compound
TWI300409B (en) 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound
EP1731518B1 (en) 2004-03-31 2014-06-25 Nippon Soda Co., Ltd. Cyclic amine compound and pest control agent
JP4787529B2 (ja) * 2004-04-09 2011-10-05 大塚製薬株式会社 医薬組成物
JP4789966B2 (ja) * 2004-04-09 2011-10-12 大塚製薬株式会社 医薬組成物
MX2007016523A (es) * 2005-06-20 2008-03-06 Schering Corp Piperidinas sustituidas ligadas a carbono y derivados de las mismas utiles como antagonistas de hsitamina h3.
UA95251C2 (ru) * 2005-07-28 2011-07-25 Оцука Фармасьютикал Ко., Лтд. ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ПРОИЗВОДНЫЕ 2,3-ДИГИДРО-6-НИТРОИМИДАЗО[2,1-b]ОКСАЗОЛА
JP5105818B2 (ja) * 2005-10-05 2012-12-26 大塚製薬株式会社 医薬組成物
TW201434467A (zh) * 2005-10-05 2014-09-16 Otsuka Pharma Co Ltd 抗結核治療藥物及含彼之套組
WO2007040280A1 (ja) * 2005-10-06 2007-04-12 Nippon Soda Co., Ltd. 環状アミン化合物および有害生物防除剤
TW200800268A (en) * 2005-11-04 2008-01-01 Otsuka Pharma Co Ltd Medicinal composition showing improved drug absorbability
US7750012B2 (en) 2005-12-21 2010-07-06 Decode Genetics Ehf Biaryl nitrogen-heterocycle inhibitors of LTA4H for treating inflammation
EP1986637A1 (en) * 2006-02-13 2008-11-05 Laboratoires Serono SA Sulfonamide derivatives for the treatment of bacterial infections
JP2007297305A (ja) * 2006-04-28 2007-11-15 Daiso Co Ltd Ｎ−（２，３−エポキシ−２−メチルプロピル）フタルイミドの製造法
WO2008106128A2 (en) * 2007-02-26 2008-09-04 Vitae Pharmaceuticals, Inc. CYCLIC UREA AND CARBAMATE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1
AR070301A1 (es) 2007-05-08 2010-03-31 Otsuka Pharma Co Ltd Compuesto epoxi y metodo para producir el mismo
CA2697168A1 (en) * 2007-07-26 2009-02-05 Vitae Pharmaceuticals, Inc. Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
AR067927A1 (es) * 2007-08-15 2009-10-28 Glaxo Group Ltd Quinolinas sustituidas, composiciones y combinaciones que las comprenden y el uso de las mismas en la preparacion de un medicamento para tratamiento de enfermedades inflamatorias y/o alergicas del tracto respiratorio.
US20100222349A1 (en) * 2007-10-16 2010-09-02 Glaxo Group Limited Quinoline derivatives used to treat inflammatory and allergic diseases
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
EP2252601B1 (en) 2008-01-24 2012-12-19 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2714532A1 (en) * 2008-02-11 2009-08-20 Vitae Pharmaceuticals, Inc. 1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
CA2715290A1 (en) * 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2274287B1 (en) * 2008-03-18 2016-03-09 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
CN101965353B (zh) * 2008-03-26 2014-12-17 丹诺医药(苏州）有限公司 共价连接到取代苯基噁唑烷酮的双环硝基咪唑类
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134400A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134384A1 (en) * 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8114868B2 (en) 2008-07-25 2012-02-14 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2010127237A2 (en) * 2009-04-30 2010-11-04 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US9643922B2 (en) 2008-08-18 2017-05-09 Yale University MIF modulators
MX2011001872A (es) * 2008-08-18 2011-05-23 Univ Yale Moduladores de mif.
US9540322B2 (en) 2008-08-18 2017-01-10 Yale University MIF modulators
WO2010143007A1 (en) * 2009-06-10 2010-12-16 Dynamit Nobel Gmbh Explosivstoff-Und Systemtechnik Method for the production of 2-halogeno-4-nitroimidazole
EP2323990B1 (en) 2008-08-21 2014-06-18 Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Methods for the production of 2-halo-4-nitroimidazole and intermediates thereof
WO2010089303A1 (en) 2009-02-04 2010-08-12 Boehringer Ingelheim International Gmbh CYCLIC INHIBITORS OF 11 β-HYDROXYSTEROID DEHYDROGENASE 1
TW201039034A (en) * 2009-04-27 2010-11-01 Chunghwa Picture Tubes Ltd Pixel structure and the method of forming the same
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
US8883778B2 (en) 2009-07-01 2014-11-11 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
JP5781072B2 (ja) * 2009-07-31 2015-09-16 グローバル、アライアンス、フォア、ティービー、ドラッグ、ディベロップメント ニトロイミダゾオキサジンおよび抗−結核療法におけるその使用
US9198913B2 (en) 2009-07-31 2015-12-01 Global Alliance For Tb Drug Development Nitroimidazooxazines and their uses in anti-tubercular therapy
NZ598165A (en) * 2009-07-31 2013-05-31 Global Alliance For Tb Drug Dev Nitroimidazooxazine and nitroimidazooxazole analogues and their uses
US20120219500A1 (en) 2009-10-26 2012-08-30 Fujifilm Ri Pharma Co., Ltd. Diagnostic agent for infectious diseases
TW201200523A (en) 2010-01-29 2012-01-01 Otsuka Pharma Co Ltd Synthetic intermediate of oxazole compound and method for producing the same
GB201012209D0 (en) * 2010-05-31 2010-09-08 Ge Healthcare Ltd In vivo imaging agent
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
JP5813106B2 (ja) 2010-06-25 2015-11-17 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 代謝障害の処置のための１１−β−ＨＳＤ１のインヒビターとしてのアザスピロヘキサノン
CA2813671A1 (en) 2010-11-02 2012-05-10 Boehringer Ingelheim International Gmbh Pharmaceutical combinations for the treatment of metabolic disorders
EP2697232B1 (en) 2011-04-15 2016-05-18 Otsuka Pharmaceutical Co., Ltd. 6,7-dihydroimidazo[2,1-b][1,3]oxazine bactericides
JP2015006994A (ja) * 2011-10-28 2015-01-15 大正製薬株式会社 ジヒドロイミダゾオキサゾール誘導体
WO2014014845A1 (en) 2012-07-18 2014-01-23 Vertex Pharmaceuticals Incorporated Combination therapy comprising|1 -ethyl-3-[5-[2-{1 -hydroxy-1 -methyl-ethyl}pyrimidin-5-yl]-7-(tetra hydrofuran-2-|yl}-1 h-benzimidazol-2-yl]urea and derivatives thereof to treat mycobacterium|diseases
FR3000064A1 (fr) 2012-12-21 2014-06-27 Univ Lille Ii Droit & Sante Composes de type spiroisoxazoline ayant une activite potentialisatrice de l'activite d'un antibiotique-composition et produit pharmaceutiques comprenant de tels composes
EP3052503B1 (en) * 2013-10-04 2018-10-24 Council of Scientific & Industrial Research 6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles and a process for the preparation thereof
CN103524492A (zh) * 2013-10-23 2014-01-22 中国药科大学 侧链含硝基咪唑基团取代的喹诺酮类化合物、其制备及用途
AR101704A1 (es) 2014-08-28 2017-01-04 Otsuka Pharma Co Ltd Compuestos heterocíclicos fusionados
CN107108650B (zh) * 2014-10-21 2019-10-18 印度科学工业研究所 抗分枝杆菌剂取代的1,2,3-三唑-1-基-甲基-2,3-二氢-2-甲基-6-硝基咪唑并[2,1-b]噁唑及其制备方法
CN105732659B (zh) * 2014-12-12 2019-07-16 上海阳帆医药科技有限公司 硝基咪唑类化合物及其制备方法和在制药中的用途
TW201632533A (zh) * 2015-01-29 2016-09-16 南京明德新藥研發股份有限公司 抗肺結核病的硝基咪唑衍生物
EP3275862B1 (en) 2015-03-27 2020-08-12 Otsuka Pharmaceutical Co., Ltd. Method for producing 1-(4-hydroxyphenyl)-4-(4-trifluoromethoxyphenoxy)piperidine or salt thereof
CN106317072B (zh) * 2015-06-17 2020-03-17 盟科医药技术(上海)有限公司 用于分枝杆菌感染治疗的杂环化合物及其应用
CN108884044B (zh) 2016-02-26 2023-01-31 大塚制药株式会社 哌啶衍生物
CN105859628B (zh) * 2016-04-19 2018-08-07 清远职业技术学院 一种抗菌化合物对n咪唑苯甲醛缩邻甲苯胺希夫碱及其制备方法和应用
BR112019001163A2 (pt) * 2016-07-22 2019-04-30 Medshine Discovery Inc. cristal e sal de nitroimidazol e método de fabricação do mesmo
SG11202000988RA (en) 2017-08-16 2020-03-30 Glaxosmithkline Ip Dev Ltd Novel compounds
SG11202011908YA (en) 2018-06-11 2020-12-30 Otsuka Pharma Co Ltd Delamanid-containing composition
CN109705022A (zh) * 2018-12-28 2019-05-03 上海彩迩文生化科技有限公司 一种芳香胺中间体的制备方法
CN112300192B (zh) * 2019-08-02 2023-08-11 南京长澳医药科技有限公司 硝基咪唑类化合物及其制备方法和用途
CN110483549B (zh) * 2019-08-30 2021-03-05 沈阳药科大学 一种硝基咪唑吡喃类抗结核药物的制备方法
CN110615800A (zh) * 2019-10-16 2019-12-27 李丽丽 硝基咪唑类化合物及其制备方法和用途
CN112156088B (zh) * 2020-10-30 2021-08-31 健民药业集团股份有限公司 一种化合物在制备结核分枝杆菌抑制剂中的用途
CN113603706A (zh) * 2021-08-04 2021-11-05 深圳市泰力生物医药有限公司 德拉马尼的晶型、含有该晶型的活性药物和药物组合物
JPWO2024024938A1 (Direct) 2022-07-29 2024-02-01
CN115368252B (zh) * 2022-09-19 2024-01-12 西北农林科技大学 一种4-胺基酚类衍生物及应用
CN116640106B (zh) * 2023-05-11 2024-03-08 郑州大学 一种苯基哌嗪类化合物及其制备方法、应用
CN119059990B (zh) * 2024-11-01 2025-02-07 安徽昊帆生物有限公司 1-氨基甲酸叔丁酯哌嗪的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668127A (en) 1995-06-26 1997-09-16 Pathogenesis Corporation Nitroimidazole antibacterial compounds and methods of use thereof

Also Published As

Publication number Publication date
EP1555267A4 (en) 2010-08-18
ZA200501033B (en) 2006-06-28
CY1113578T1 (el) 2016-06-22
LU92517I2 (fr) 2014-10-13
HUS1400046I1 (hu) 2017-04-28
CN101255170A (zh) 2008-09-03
EP2570418A3 (en) 2013-07-03
RU2005114017A (ru) 2006-01-20
AU2003272979B2 (en) 2009-07-23
PL404913A1 (pl) 2013-09-30
KR100723847B1 (ko) 2007-05-31
US7262212B2 (en) 2007-08-28
AR086485A2 (es) 2013-12-18
KR20050061473A (ko) 2005-06-22
CN102532162A (zh) 2012-07-04
SI1555267T1 (sl) 2013-05-31
AR041198A1 (es) 2005-05-04
HK1085463A1 (zh) 2006-08-25
BRPI0314344B1 (pt) 2019-11-26
ES2400179T3 (es) 2013-04-08
PL409525A1 (pl) 2014-11-10
BR0314344A (pt) 2005-07-12
PL376157A1 (en) 2005-12-27
CN100366624C (zh) 2008-02-06
US20060094767A1 (en) 2006-05-04
DK1555267T3 (da) 2013-02-11
EP1555267A1 (en) 2005-07-20
CY2014041I2 (el) 2016-07-27
EP2570418A2 (en) 2013-03-20
AR089950A2 (es) 2014-10-01
CN1705670A (zh) 2005-12-07
AR091771A2 (es) 2015-02-25
EP1555267B1 (en) 2013-01-16
MXPA05003674A (es) 2005-06-08
AU2003272979A1 (en) 2004-05-04
PT1555267E (pt) 2013-01-29
TW200420568A (en) 2004-10-16
WO2004033463A1 (ja) 2004-04-22
JP2004149527A (ja) 2004-05-27
RU2326121C2 (ru) 2008-06-10
CA2497569A1 (en) 2004-04-22
JP4186065B2 (ja) 2008-11-26
CY2014041I1 (el) 2016-07-27
HK1171018A1 (en) 2013-03-15
PL217919B1 (pl) 2014-09-30
TWI347946B (en) 2011-09-01
BRPI0314344B8 (pt) 2021-05-25
BE2014C053I2 (Direct) 2022-08-30
RU2326121C3 (ru) 2021-09-17
MY139244A (en) 2009-09-30
CA2497569C (en) 2011-05-24
CN102532162B (zh) 2015-05-27
FR14C0066I2 (fr) 2015-05-22
CN101172981A (zh) 2008-05-07
FR14C0066I1 (Direct) 2014-10-17

Similar Documents

Publication Publication Date Title
UA83200C2 (en) 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES
MX2009003073A (es) Derivado de 2-piridincarboxamida que tiene efecto activador de gk.
MY146646A (en) 2,3-dihydro-6-nitroimidazo [2,1-b] oxazole compounds for the treatment of tuberculosis
MXPA05009059A (es) Derivados de heteroarilcarbamoilbenceno.
PH12012501711A1 (en) [5,6] heterocyclic compound
TW200736363A (en) Material for organic electroluminescent device and organic electroluminescent device
MY155655A (en) Cephalosporin having catechol group
UA83243C2 (ru) Соединения, которые ингибируют натриезависимый переносчик глюкозы
GEP20074210B (en) Tropane derivatives as ccr5 modulators
MXPA05008619A (es) Derivados novedosos de 2-piridincarboxamida.
DE60214591D1 (en) Pyrazolpyrimidinfungizide
MXPA06001273A (es) Compuestos novedosos.
EP1527049B8 (en) Fused heterocyclic compounds as peptidase inhibitors
IL186815A (en) A 3-amino-3-alkyl-4-quinolone compound mono or 3-amino-3-alkyl-4, 4-substituted by pyrrolidinyl
PH12009500610A1 (en) 4-imidazolin-2-one compounds
TW200745034A (en) New compounds
TW200503712A (en) (2-carboxamido)(3-amino)thiophene compounds
WO2005065050A3 (ja) ２環化合物
MY140749A (en) Novel piperidine compound
TNSN07357A1 (en) Indanyl-piperazine derivatives, method for preparing same and pharmaceutical compositions containing same
TW200616969A (en) Imidazole compound
MX2009007058A (es) Compuesto triciclico y uso farmaceutico del mismo.
TW200609218A (en) Bicyclic compounds
WO2007033039A3 (en) Proteasome inhibiting beta lactam compounds
EP1325912A4 (en) 2,2-DIPHENYLBUTANAMIDE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS