ES2400179T3 - 2-3-dihidro-6-nitroimidazol[2,1-b]oxazoles - Google Patents

2-3-dihidro-6-nitroimidazol[2,1-b]oxazoles Download PDF

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Publication number
ES2400179T3
ES2400179T3 ES03754085T ES03754085T ES2400179T3 ES 2400179 T3 ES2400179 T3 ES 2400179T3 ES 03754085 T ES03754085 T ES 03754085T ES 03754085 T ES03754085 T ES 03754085T ES 2400179 T3 ES2400179 T3 ES 2400179T3
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Spain
Prior art keywords
group
substituted
halogen
unsubstituted
methyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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ES03754085T
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English (en)
Spanish (es)
Inventor
Hidetsugu Tsubouchi
Hirofumi Sasaki
Hideaki Kuroda
Motohiro Itotani
Takeshi Hasegawa
Yoshikazu Haraguchi
Takeshi Kuroda
Takayuki Matsuzaki
Kuninori Tai
Makoto Komatsu
Makoto Matsumoto
Hiroyuki Hashizume
Tatsuo Tomishige
Yuji Seike
Masanori Kawasaki
Takumi Sumida
Shin Miyamura
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Otsuka Pharmaceutical Co Ltd
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Otsuka Pharmaceutical Co Ltd
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Application granted granted Critical
Publication of ES2400179T3 publication Critical patent/ES2400179T3/es
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ES03754085T 2002-10-11 2003-10-10 2-3-dihidro-6-nitroimidazol[2,1-b]oxazoles Expired - Lifetime ES2400179T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002298259 2002-10-11
JP2002298259 2002-10-11
PCT/JP2003/013070 WO2004033463A1 (ja) 2002-10-11 2003-10-10 ２，３−ジヒドロ−６−ニトロイミダゾ[２，１−ｂ]オキサゾール化合物

Publications (1)

Publication Number Publication Date
ES2400179T3 true ES2400179T3 (es) 2013-04-08

Family

ID=32089299

Family Applications (1)

Application Number Title Priority Date Filing Date
ES03754085T Expired - Lifetime ES2400179T3 (es) 2002-10-11 2003-10-10 2-3-dihidro-6-nitroimidazol[2,1-b]oxazoles

Country Status (26)

Country Link
US (1) US7262212B2 (Direct)
EP (2) EP1555267B1 (Direct)
JP (1) JP4186065B2 (Direct)
KR (1) KR100723847B1 (Direct)
CN (4) CN101172981A (Direct)
AR (4) AR041198A1 (Direct)
AU (1) AU2003272979B2 (Direct)
BE (1) BE2014C053I2 (Direct)
BR (1) BRPI0314344B8 (Direct)
CA (1) CA2497569C (Direct)
CY (2) CY1113578T1 (Direct)
DK (1) DK1555267T3 (Direct)
ES (1) ES2400179T3 (Direct)
FR (1) FR14C0066I2 (Direct)
HU (1) HUS1400046I1 (Direct)
LU (1) LU92517I2 (Direct)
MX (1) MXPA05003674A (Direct)
MY (1) MY139244A (Direct)
PL (3) PL217919B1 (Direct)
PT (1) PT1555267E (Direct)
RU (1) RU2326121C3 (Direct)
SI (1) SI1555267T1 (Direct)
TW (1) TWI347946B (Direct)
UA (1) UA83200C2 (Direct)
WO (1) WO2004033463A1 (Direct)
ZA (1) ZA200501033B (Direct)

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CN110483549B (zh) * 2019-08-30 2021-03-05 沈阳药科大学 一种硝基咪唑吡喃类抗结核药物的制备方法
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CN112156088B (zh) * 2020-10-30 2021-08-31 健民药业集团股份有限公司 一种化合物在制备结核分枝杆菌抑制剂中的用途
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EP1555267A4 (en) 2010-08-18
ZA200501033B (en) 2006-06-28
CY1113578T1 (el) 2016-06-22
LU92517I2 (fr) 2014-10-13
HUS1400046I1 (hu) 2017-04-28
CN101255170A (zh) 2008-09-03
EP2570418A3 (en) 2013-07-03
RU2005114017A (ru) 2006-01-20
AU2003272979B2 (en) 2009-07-23
PL404913A1 (pl) 2013-09-30
KR100723847B1 (ko) 2007-05-31
US7262212B2 (en) 2007-08-28
AR086485A2 (es) 2013-12-18
KR20050061473A (ko) 2005-06-22
CN102532162A (zh) 2012-07-04
SI1555267T1 (sl) 2013-05-31
UA83200C2 (en) 2008-06-25
AR041198A1 (es) 2005-05-04
HK1085463A1 (zh) 2006-08-25
BRPI0314344B1 (pt) 2019-11-26
PL409525A1 (pl) 2014-11-10
BR0314344A (pt) 2005-07-12
PL376157A1 (en) 2005-12-27
CN100366624C (zh) 2008-02-06
US20060094767A1 (en) 2006-05-04
DK1555267T3 (da) 2013-02-11
EP1555267A1 (en) 2005-07-20
CY2014041I2 (el) 2016-07-27
EP2570418A2 (en) 2013-03-20
AR089950A2 (es) 2014-10-01
CN1705670A (zh) 2005-12-07
AR091771A2 (es) 2015-02-25
EP1555267B1 (en) 2013-01-16
MXPA05003674A (es) 2005-06-08
AU2003272979A1 (en) 2004-05-04
PT1555267E (pt) 2013-01-29
TW200420568A (en) 2004-10-16
WO2004033463A1 (ja) 2004-04-22
JP2004149527A (ja) 2004-05-27
RU2326121C2 (ru) 2008-06-10
CA2497569A1 (en) 2004-04-22
JP4186065B2 (ja) 2008-11-26
CY2014041I1 (el) 2016-07-27
HK1171018A1 (en) 2013-03-15
PL217919B1 (pl) 2014-09-30
TWI347946B (en) 2011-09-01
BRPI0314344B8 (pt) 2021-05-25
BE2014C053I2 (Direct) 2022-08-30
RU2326121C3 (ru) 2021-09-17
MY139244A (en) 2009-09-30
CA2497569C (en) 2011-05-24
CN102532162B (zh) 2015-05-27
FR14C0066I2 (fr) 2015-05-22
CN101172981A (zh) 2008-05-07
FR14C0066I1 (Direct) 2014-10-17

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