UA75714C2 - 3-azabicyclo [3.1.0] hexane derivatives as opioid receptor antagonists and pharmaceutical composition based thereon - Google Patents
3-azabicyclo [3.1.0] hexane derivatives as opioid receptor antagonists and pharmaceutical composition based thereon Download PDFInfo
- Publication number
- UA75714C2 UA75714C2 UA20040402979A UA20040402979A UA75714C2 UA 75714 C2 UA75714 C2 UA 75714C2 UA 20040402979 A UA20040402979 A UA 20040402979A UA 20040402979 A UA20040402979 A UA 20040402979A UA 75714 C2 UA75714 C2 UA 75714C2
- Authority
- UA
- Ukraine
- Prior art keywords
- exo
- ethyl
- hex
- azabicyclo
- propyl
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33851101P | 2001-10-22 | 2001-10-22 | |
| PCT/IB2002/003668 WO2003035622A1 (en) | 2001-10-22 | 2002-09-09 | 3-azabicyclo (3.1.0) hexane derivatives as opioid receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA75714C2 true UA75714C2 (en) | 2006-05-15 |
Family
ID=23325099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA20040402979A UA75714C2 (en) | 2001-10-22 | 2002-09-09 | 3-azabicyclo [3.1.0] hexane derivatives as opioid receptor antagonists and pharmaceutical composition based thereon |
Country Status (42)
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0209129A (pt) | 2001-04-18 | 2005-12-20 | Euro Celtique Sa | Compostos, composições farmacêuticas, métodos para tratamento de dores, métodos para modulação de uma resposta farmacológica e usos de compostos |
| DE60226161T2 (de) * | 2001-10-22 | 2009-07-02 | Pfizer Products Inc., Groton | 3-azabicyclo[3.1.0]hexan derivative als antagonisten der opioid rezeptoren |
| MXPA05011070A (es) * | 2003-04-14 | 2005-12-12 | Pfizer Prod Inc | Derivados de 3-azabiciclo [3.2.1] octano. |
| US20050043327A1 (en) * | 2003-08-21 | 2005-02-24 | Pfizer Inc | Pharmaceutical composition for the prevention and treatment of addiction in a mammal |
| US7153976B2 (en) * | 2003-10-06 | 2006-12-26 | Pfizer Inc. | Purification process for an azabicyclo[3.1.0]hexane compound |
| ES2634841T3 (es) * | 2003-10-14 | 2017-09-29 | Pfizer Products Inc. | Derivados bicíclicos [3.1.0] como inhibidores del transportador de glicina |
| EP1675829A1 (en) * | 2003-10-16 | 2006-07-05 | Pfizer Products Inc. | Preparation of 3-azabicyclo [3.1.0] hexane derivatives |
| ATE451364T1 (de) | 2004-02-23 | 2009-12-15 | Glaxo Group Ltd | Als modulatoren des dopamin-d3-rezeptors geeignete azabicycloä3.1.0ühexanderivate |
| AU2005219785B2 (en) * | 2004-03-05 | 2010-05-27 | Msd K.K. | Cycloalkanopyridine derivative |
| EP1837022A4 (en) * | 2004-12-14 | 2009-12-16 | Toray Industries | INDOLOMORPHINANE DERIVATIVE WITH CARBOXY IN 6 'POSITION |
| GB0512099D0 (en) * | 2005-06-14 | 2005-07-20 | Glaxo Group Ltd | Compounds |
| GB0517191D0 (en) * | 2005-08-22 | 2005-09-28 | Glaxo Group Ltd | Compounds |
| US7592461B2 (en) | 2005-12-21 | 2009-09-22 | Bristol-Myers Squibb Company | Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
| MY145633A (en) | 2006-03-01 | 2012-03-15 | Theravance Inc | 8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists |
| WO2008075162A2 (en) * | 2006-12-15 | 2008-06-26 | Pfizer Limited | Selective mu opioid receptor antagonists for the treatment of female sexual dysfunction |
| TWI409067B (zh) * | 2007-02-28 | 2013-09-21 | Theravance Inc | ８-氮雜雙環〔３．２．１〕辛烷化合物之結晶型 |
| ES2390195T3 (es) * | 2007-08-27 | 2012-11-07 | Theravance, Inc. | Compuestos de amidoalquil-8-azabiciclo(3,2,1)octano, como antagonistas del receptor opioide mu |
| US7947710B2 (en) * | 2007-08-27 | 2011-05-24 | Theravance, Inc. | Disubstituted alkyl-8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists |
| TWI423801B (zh) * | 2007-08-27 | 2014-01-21 | Theravance Inc | 作為μ類鴉片受體拮抗劑之８－氮雜雙環〔３．２．１〕辛基－２－羥基苯甲醯胺化合物 |
| WO2009029253A1 (en) * | 2007-08-27 | 2009-03-05 | Theravance, Inc. | Heteroarylalkyl-8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists |
| BR112013007566A2 (pt) | 2010-09-28 | 2016-08-02 | Panacea Biotec Ltd | novos compostos bicíclicos |
| CA2927527C (en) * | 2013-11-20 | 2021-06-01 | Sanwa Kagaku Kenkyusho Co., Ltd. | Novel 3-azabicyclo[3.1.0]hexane derivative and use thereof as u-opioid receptor antagonist |
| HK1246778A1 (zh) * | 2015-05-20 | 2018-09-14 | 株式会社三和化学研究所 | 一种新型的3-氮杂双环[3.1.0]己烷衍生物的盐的晶体以及其医药应用 |
| EP3590511A4 (en) | 2017-03-02 | 2020-09-02 | Sanwa Kagaku Kenkyusho Co., Ltd | THERAPEUTIC AGENT FOR DISORDERS RELATED TO THE CONSUMPTION OF ALCOHOL |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2099214A (en) * | 1937-11-16 | Process fob forming the sulphuric | ||
| US2099216A (en) * | 1934-05-04 | 1937-11-16 | Frederick H Nass | Metal testing machine |
| US3004340A (en) * | 1959-09-24 | 1961-10-17 | Bernice L Collins | Kitchen utensil |
| US3078282A (en) * | 1960-01-02 | 1963-02-19 | Bayer Ag | Anthraquinone dyestuffs |
| ATE110057T1 (de) | 1987-04-16 | 1994-09-15 | Lilly Co Eli | Piperidine als opioid-antagoniste. |
| JPH04155522A (ja) * | 1990-10-19 | 1992-05-28 | Nec Corp | ファースト・イン・ランダム・アウト回路 |
| ZA922180B (en) | 1991-03-29 | 1993-09-27 | Lilly Co Eli | Piperidine derivatives |
| US5159081A (en) | 1991-03-29 | 1992-10-27 | Eli Lilly And Company | Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists |
| GB9725114D0 (en) * | 1997-11-28 | 1998-01-28 | Pfizer Ltd | Treatment of pruritus |
| GB9810671D0 (en) * | 1998-05-18 | 1998-07-15 | Pfizer Ltd | Anti-pruritic agents |
| TWI244481B (en) * | 1998-12-23 | 2005-12-01 | Pfizer | 3-azabicyclo[3.1.0]hexane derivatives useful in therapy |
| GB9912415D0 (en) * | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
| GB9912413D0 (en) * | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
| GB9912410D0 (en) * | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
| GB9912411D0 (en) * | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
| US20020064825A1 (en) * | 2000-05-19 | 2002-05-30 | Lewis Marilyn Evelyn | Novel polypeptide |
| US20030207876A1 (en) * | 2000-06-23 | 2003-11-06 | Banks Bernard Joseph | 3-Azabicyclo[3.1.0]hexane derivatives useful in therapy |
| GB0015562D0 (en) * | 2000-06-23 | 2000-08-16 | Pfizer Ltd | Heterocycles |
| US20020025948A1 (en) * | 2000-06-23 | 2002-02-28 | Banks Bernard Joseph | 3-azabicyclo[3.1.0]hexane derivatives useful in therapy |
| DE10042885A1 (de) * | 2000-08-31 | 2002-03-14 | Heidelberger Druckmasch Ag | Bogentransportzylinder |
| DE60226161T2 (de) | 2001-10-22 | 2009-07-02 | Pfizer Products Inc., Groton | 3-azabicyclo[3.1.0]hexan derivative als antagonisten der opioid rezeptoren |
| AU2003239389A1 (en) | 2002-05-30 | 2003-12-19 | Eli Lilly And Company | Opioid receptor antagonists |
| US7056930B2 (en) * | 2003-04-14 | 2006-06-06 | Pfizer Inc. | 2-Azabicyclo[3.3.1]nonane derivatives |
| US20040204453A1 (en) * | 2003-04-14 | 2004-10-14 | Pfizer Inc | 4-Phenyl-piperidine compounds and their use as modulators of opioid receptors |
| US20050043327A1 (en) * | 2003-08-21 | 2005-02-24 | Pfizer Inc | Pharmaceutical composition for the prevention and treatment of addiction in a mammal |
| US7153976B2 (en) * | 2003-10-06 | 2006-12-26 | Pfizer Inc. | Purification process for an azabicyclo[3.1.0]hexane compound |
-
2002
- 2002-09-09 DE DE60226161T patent/DE60226161T2/de not_active Expired - Lifetime
- 2002-09-09 ES ES02765197T patent/ES2302839T3/es not_active Expired - Lifetime
- 2002-09-09 NZ NZ531807A patent/NZ531807A/xx unknown
- 2002-09-09 KR KR1020047006011A patent/KR100621292B1/ko not_active Expired - Fee Related
- 2002-09-09 WO PCT/IB2002/003668 patent/WO2003035622A1/en not_active Ceased
- 2002-09-09 GE GEAP20028173A patent/GEP20084300B/en unknown
- 2002-09-09 HU HU0401884A patent/HUP0401884A2/hu unknown
- 2002-09-09 JP JP2003538138A patent/JP4155522B2/ja not_active Expired - Fee Related
- 2002-09-09 OA OA1200400109A patent/OA12711A/en unknown
- 2002-09-09 DK DK02765197T patent/DK1440059T3/da active
- 2002-09-09 SI SI200230688T patent/SI1440059T1/sl unknown
- 2002-09-09 AP APAP/P/2004/003007A patent/AP1816A/en active
- 2002-09-09 PT PT02765197T patent/PT1440059E/pt unknown
- 2002-09-09 EA EA200400467A patent/EA006708B1/ru not_active IP Right Cessation
- 2002-09-09 MX MXPA04003730A patent/MXPA04003730A/es active IP Right Grant
- 2002-09-09 EP EP02765197A patent/EP1440059B1/en not_active Expired - Lifetime
- 2002-09-09 AU AU2002329557A patent/AU2002329557B2/en not_active Ceased
- 2002-09-09 RS YUP-251/04A patent/RS25104A/sr unknown
- 2002-09-09 CA CA002463264A patent/CA2463264C/en not_active Expired - Fee Related
- 2002-09-09 UA UA20040402979A patent/UA75714C2/uk unknown
- 2002-09-09 HR HRP20040288 patent/HRP20040288A2/hr not_active Application Discontinuation
- 2002-09-09 IL IL16115702A patent/IL161157A0/xx unknown
- 2002-09-09 BR BR0213464-0A patent/BR0213464A/pt not_active IP Right Cessation
- 2002-09-09 AT AT02765197T patent/ATE392415T1/de not_active IP Right Cessation
- 2002-09-09 PL PL02368919A patent/PL368919A1/xx not_active Application Discontinuation
- 2002-09-09 CN CNB028208854A patent/CN100368398C/zh not_active Expired - Fee Related
- 2002-10-16 PY PY200200225353A patent/PY0225353A/es unknown
- 2002-10-17 MY MYPI20023878A patent/MY136580A/en unknown
- 2002-10-17 PA PA20028556701A patent/PA8556701A1/es unknown
- 2002-10-18 PE PE2002001032A patent/PE20030610A1/es not_active Application Discontinuation
- 2002-10-18 HN HN2002000299A patent/HN2002000299A/es unknown
- 2002-10-21 SV SV2002001363A patent/SV2004001363A/es not_active Application Discontinuation
- 2002-10-21 AR ARP020103960A patent/AR036905A1/es unknown
- 2002-10-22 US US10/278,142 patent/US7049335B2/en not_active Expired - Fee Related
- 2002-10-22 GT GT200200216A patent/GT200200216A/es unknown
-
2004
- 2004-03-18 IS IS7187A patent/IS7187A/is unknown
- 2004-03-18 ZA ZA200402172A patent/ZA200402172B/en unknown
- 2004-03-29 IL IL161157A patent/IL161157A/en not_active IP Right Cessation
- 2004-04-15 MA MA27630A patent/MA27141A1/fr unknown
- 2004-04-20 CR CR7317A patent/CR7317A/es unknown
- 2004-04-21 NO NO20041626A patent/NO329092B1/no not_active IP Right Cessation
- 2004-04-21 TN TNP2004000071A patent/TNSN04071A1/fr unknown
- 2004-04-22 EC EC2004005077A patent/ECSP045077A/es unknown
-
2005
- 2005-02-24 US US11/066,095 patent/US20050171178A1/en not_active Abandoned
-
2006
- 2006-03-01 US US11/366,903 patent/US20070054950A1/en not_active Abandoned
-
2007
- 2007-10-19 JP JP2007272602A patent/JP2008069169A/ja active Pending
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