UA75425C2 - Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds - Google Patents
Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds Download PDFInfo
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- UA75425C2 UA75425C2 UA2004020930A UA2004020930A UA75425C2 UA 75425 C2 UA75425 C2 UA 75425C2 UA 2004020930 A UA2004020930 A UA 2004020930A UA 2004020930 A UA2004020930 A UA 2004020930A UA 75425 C2 UA75425 C2 UA 75425C2
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- ylmethyl
- disorders
- indol
- compounds
- bis
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202631 | 2001-07-09 | ||
| PCT/EP2002/007472 WO2003006459A1 (en) | 2001-07-09 | 2002-07-03 | Piperazine oxime derivatives having nk-1 receptor antagonistic activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA75425C2 true UA75425C2 (en) | 2006-04-17 |
Family
ID=8180620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| UA2004020930A UA75425C2 (en) | 2001-07-09 | 2002-03-07 | Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds |
Country Status (26)
| Country | Link |
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| US (1) | US7094779B2 (sl) |
| EP (1) | EP1406894B1 (sl) |
| JP (1) | JP3765543B2 (sl) |
| KR (1) | KR100900889B1 (sl) |
| CN (1) | CN1223591C (sl) |
| AR (1) | AR034722A1 (sl) |
| AT (1) | ATE285407T1 (sl) |
| AU (1) | AU2002333229B2 (sl) |
| BR (1) | BR0210080A (sl) |
| CA (1) | CA2446726A1 (sl) |
| DE (1) | DE60202371T2 (sl) |
| DK (1) | DK1406894T3 (sl) |
| ES (1) | ES2230521T3 (sl) |
| HK (1) | HK1067364A1 (sl) |
| HR (1) | HRP20030912A2 (sl) |
| HU (1) | HUP0401093A3 (sl) |
| IL (2) | IL158728A0 (sl) |
| MX (1) | MXPA04000230A (sl) |
| NO (1) | NO20040065L (sl) |
| PL (1) | PL366841A1 (sl) |
| PT (1) | PT1406894E (sl) |
| RU (1) | RU2273639C2 (sl) |
| SI (1) | SI1406894T1 (sl) |
| UA (1) | UA75425C2 (sl) |
| WO (1) | WO2003006459A1 (sl) |
| ZA (1) | ZA200308782B (sl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005062795A2 (en) | 2003-12-19 | 2005-07-14 | Plexxikon, Inc. | Compounds and methods for development of ret modulators |
| US7498342B2 (en) | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
| KR100616099B1 (ko) * | 2004-09-20 | 2006-08-28 | 한국과학기술연구원 | Ｔ-타입 칼슘채널 길항제로 유효한 신규 피페라지닐알킬이소옥사졸 유도체 |
| AU2006272951A1 (en) | 2005-05-17 | 2007-02-01 | Plexxikon, Inc. | Pyrrol (2,3-b) pyridine derivatives protein kinase inhibitors |
| EP1893612B1 (en) | 2005-06-22 | 2011-08-03 | Plexxikon, Inc. | Pyrrolo [2, 3-b]pyridine derivatives as protein kinase inhibitors |
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| US20100168197A1 (en) * | 2007-02-28 | 2010-07-01 | Naresh Kumar | Muscarinic receptor antagonists |
| WO2009012283A1 (en) | 2007-07-17 | 2009-01-22 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| SG173178A1 (en) | 2009-04-03 | 2011-09-29 | Hoffmann La Roche | Propane- i-sulfonic acid {3- [5- (4 -chloro-phenyl) -1h-pyrrolo [2, 3-b] pyridine-3-carbonyl] -2, 4-difluoro-pheny l } -amide compositions and uses thereof |
| NZ629615A (en) | 2009-11-06 | 2016-01-29 | Plexxikon Inc | Compounds and methods for kinase modulation, and indications therefor |
| EA028821B9 (ru) | 2011-02-07 | 2018-10-31 | Плексксикон, Инк. | Соединения и способы для модуляции киназ, а также показания к их применению |
| TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
| US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
| CN104958297A (zh) * | 2015-06-03 | 2015-10-07 | 周玉梅 | 一种用于麻醉镇静催眠的药物组合物及其应用 |
| CN110615774B (zh) * | 2019-09-19 | 2022-11-11 | 安徽中医药大学 | 具有抗炎活性的苄基哌嗪类化合物、制法及医药用途 |
| JP2022090346A (ja) | 2020-12-07 | 2022-06-17 | 三星電子株式会社 | 共重合体、ならびに当該共重合体を用いるエレクトロルミネッセンス素子材料およびエレクトロルミネッセンス素子 |
Family Cites Families (10)
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| IL111730A (en) * | 1993-11-29 | 1998-12-06 | Fujisawa Pharmaceutical Co | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them |
| US5696267A (en) * | 1995-05-02 | 1997-12-09 | Schering Corporation | Substituted oximes, hydrazones and olefins as neurokinin antagonists |
| ATE244712T1 (de) * | 1995-05-02 | 2003-07-15 | Schering Corp | Piperazino-derivative als neurokininantagonisten |
| CN1072220C (zh) * | 1995-05-25 | 2001-10-03 | 藤泽药品工业株式会社 | 作为神经激肽受体拮抗剂的1－苯甲酰基－2－(吲哚基－3－烷基)－哌嗪衍生物 |
| JP2000502100A (ja) | 1995-12-18 | 2000-02-22 | 藤沢薬品工業株式会社 | タキキニン拮抗薬としてのピペラジン誘導体 |
| JP4189043B2 (ja) * | 1996-09-30 | 2008-12-03 | 株式会社資生堂 | Ｎ−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤 |
| AUPO735997A0 (en) * | 1997-06-17 | 1997-07-10 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives |
| DE59814233D1 (de) * | 1997-08-27 | 2008-07-03 | Solvay Pharm Gmbh | Indolmethyl-N,N'-bisacylpiperazine als Neurokininrezeptorantagonisten |
| DE19824865A1 (de) * | 1997-08-27 | 1999-03-04 | Solvay Pharm Gmbh | Neue Harnstoffderivate |
| TW533210B (en) * | 1998-12-23 | 2003-05-21 | Schering Corp | Substituted oximes and hydrazones as neurokinin antagonists |
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2002
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- 2002-07-03 DK DK02784838T patent/DK1406894T3/da active
- 2002-07-03 EP EP02784838A patent/EP1406894B1/en not_active Expired - Lifetime
- 2002-07-03 ES ES02784838T patent/ES2230521T3/es not_active Expired - Lifetime
- 2002-07-03 DE DE60202371T patent/DE60202371T2/de not_active Expired - Fee Related
- 2002-07-03 WO PCT/EP2002/007472 patent/WO2003006459A1/en active IP Right Grant
- 2002-07-03 CA CA002446726A patent/CA2446726A1/en not_active Abandoned
- 2002-07-03 JP JP2003512231A patent/JP3765543B2/ja not_active Expired - Fee Related
- 2002-07-03 KR KR1020047000273A patent/KR100900889B1/ko not_active IP Right Cessation
- 2002-07-03 BR BR0210080-0A patent/BR0210080A/pt not_active IP Right Cessation
- 2002-07-03 AT AT02784838T patent/ATE285407T1/de not_active IP Right Cessation
- 2002-07-03 MX MXPA04000230A patent/MXPA04000230A/es active IP Right Grant
- 2002-07-03 IL IL15872802A patent/IL158728A0/xx unknown
- 2002-07-03 HU HU0401093A patent/HUP0401093A3/hu unknown
- 2002-07-03 CN CNB028127307A patent/CN1223591C/zh not_active Expired - Fee Related
- 2002-07-03 PT PT02784838T patent/PT1406894E/pt unknown
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- 2002-07-04 AR ARP020102505A patent/AR034722A1/es unknown
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2003
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- 2003-11-10 HR HR20030912A patent/HRP20030912A2/xx not_active Application Discontinuation
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2004
- 2004-01-08 NO NO20040065A patent/NO20040065L/no not_active Application Discontinuation
- 2004-12-14 HK HK04109874A patent/HK1067364A1/xx not_active IP Right Cessation
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