ZA200308782B - Piperazine oxime derivatives having NK-1 receptor antagonistic activity. - Google Patents
Piperazine oxime derivatives having NK-1 receptor antagonistic activity. Download PDFInfo
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- ZA200308782B ZA200308782B ZA200308782A ZA200308782A ZA200308782B ZA 200308782 B ZA200308782 B ZA 200308782B ZA 200308782 A ZA200308782 A ZA 200308782A ZA 200308782 A ZA200308782 A ZA 200308782A ZA 200308782 B ZA200308782 B ZA 200308782B
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| US7504509B2 (en) | 2003-12-19 | 2009-03-17 | Plexxikon, Inc. | Compounds and methods for development of Ret modulators |
| US7498342B2 (en) | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
| KR100616099B1 (ko) * | 2004-09-20 | 2006-08-28 | 한국과학기술연구원 | Ｔ-타입 칼슘채널 길항제로 유효한 신규 피페라지닐알킬이소옥사졸 유도체 |
| AU2006272951A1 (en) | 2005-05-17 | 2007-02-01 | Plexxikon, Inc. | Pyrrol (2,3-b) pyridine derivatives protein kinase inhibitors |
| AU2006261993B2 (en) | 2005-06-22 | 2011-11-17 | Plexxikon, Inc. | Pyrrolo (2, 3-B) pyridine derivatives as protein kinase inhibitors |
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| US20100168197A1 (en) * | 2007-02-28 | 2010-07-01 | Naresh Kumar | Muscarinic receptor antagonists |
| EP2170830B1 (en) | 2007-07-17 | 2014-10-15 | Plexxikon, Inc. | 2-FLUORO-BENZENESULFONAMIDE COMPOUNDS AS Raf KINASE MODULATORS |
| AU2010232670B2 (en) | 2009-04-03 | 2015-07-09 | F. Hoffmann-La Roche Ag | Propane- I-sulfonic acid {3- [5- (4 -chloro-phenyl) -1H-pyrrolo [2, 3-b] pyridine-3-carbonyl] -2, 4-difluoro-pheny l } -amide compositions and uses thereof |
| PE20121327A1 (es) | 2009-11-06 | 2012-10-18 | Plexxikon Inc | Compuestos y metodos para la modulacion de cinasas, e indicaciones para ello |
| PL2672967T3 (pl) | 2011-02-07 | 2019-04-30 | Plexxikon Inc | Związki i sposoby modulacji kinaz i wskazania ku temu |
| TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
| US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
| CN104958297A (zh) * | 2015-06-03 | 2015-10-07 | 周玉梅 | 一种用于麻醉镇静催眠的药物组合物及其应用 |
| CN110615774B (zh) * | 2019-09-19 | 2022-11-11 | 安徽中医药大学 | 具有抗炎活性的苄基哌嗪类化合物、制法及医药用途 |
| JP2022090346A (ja) | 2020-12-07 | 2022-06-17 | 三星電子株式会社 | 共重合体、ならびに当該共重合体を用いるエレクトロルミネッセンス素子材料およびエレクトロルミネッセンス素子 |
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| IL111730A (en) | 1993-11-29 | 1998-12-06 | Fujisawa Pharmaceutical Co | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them |
| JP4173912B2 (ja) * | 1995-05-02 | 2008-10-29 | シェーリング コーポレイション | ニューロキニンアンタゴニストとしてのピペラジノ誘導体 |
| US5696267A (en) | 1995-05-02 | 1997-12-09 | Schering Corporation | Substituted oximes, hydrazones and olefins as neurokinin antagonists |
| CN1072220C (zh) * | 1995-05-25 | 2001-10-03 | 藤泽药品工业株式会社 | 作为神经激肽受体拮抗剂的1－苯甲酰基－2－(吲哚基－3－烷基)－哌嗪衍生物 |
| JP2000502100A (ja) * | 1995-12-18 | 2000-02-22 | 藤沢薬品工業株式会社 | タキキニン拮抗薬としてのピペラジン誘導体 |
| JP4189043B2 (ja) | 1996-09-30 | 2008-12-03 | 株式会社資生堂 | Ｎ−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤 |
| AUPO735997A0 (en) * | 1997-06-17 | 1997-07-10 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives |
| DE19824865A1 (de) * | 1997-08-27 | 1999-03-04 | Solvay Pharm Gmbh | Neue Harnstoffderivate |
| ATE396187T1 (de) | 1997-08-27 | 2008-06-15 | Solvay Pharm Gmbh | Indolmethyl-n,n'-bisacylpiperazine als neurokininrezeptorantagonisten |
| ES2226493T3 (es) * | 1998-12-23 | 2005-03-16 | Schering Corporation | Oximas e hidrazonas sustituidas como antagonistas de neroquinina. |
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