SI1406894T1 - Derivati piperazin oksima z antagonistično aktivnostjo receptorja nk-1 - Google Patents
Derivati piperazin oksima z antagonistično aktivnostjo receptorja nk-1Info
- Publication number
- SI1406894T1 SI1406894T1 SI200230060T SI200230060T SI1406894T1 SI 1406894 T1 SI1406894 T1 SI 1406894T1 SI 200230060 T SI200230060 T SI 200230060T SI 200230060 T SI200230060 T SI 200230060T SI 1406894 T1 SI1406894 T1 SI 1406894T1
- Authority
- SI
- Slovenia
- Prior art keywords
- antagonistic activity
- receptor antagonistic
- oxime derivatives
- piperazine
- piperazine oxime
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01202631 | 2001-07-09 | ||
EP02784838A EP1406894B1 (en) | 2001-07-09 | 2002-07-03 | Piperazine oxime derivatives having nk-1 receptor antagonistic activity |
PCT/EP2002/007472 WO2003006459A1 (en) | 2001-07-09 | 2002-07-03 | Piperazine oxime derivatives having nk-1 receptor antagonistic activity |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1406894T1 true SI1406894T1 (sl) | 2005-06-30 |
Family
ID=8180620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200230060T SI1406894T1 (sl) | 2001-07-09 | 2002-07-03 | Derivati piperazin oksima z antagonistično aktivnostjo receptorja nk-1 |
Country Status (26)
Country | Link |
---|---|
US (1) | US7094779B2 (sl) |
EP (1) | EP1406894B1 (sl) |
JP (1) | JP3765543B2 (sl) |
KR (1) | KR100900889B1 (sl) |
CN (1) | CN1223591C (sl) |
AR (1) | AR034722A1 (sl) |
AT (1) | ATE285407T1 (sl) |
AU (1) | AU2002333229B2 (sl) |
BR (1) | BR0210080A (sl) |
CA (1) | CA2446726A1 (sl) |
DE (1) | DE60202371T2 (sl) |
DK (1) | DK1406894T3 (sl) |
ES (1) | ES2230521T3 (sl) |
HK (1) | HK1067364A1 (sl) |
HR (1) | HRP20030912A2 (sl) |
HU (1) | HUP0401093A3 (sl) |
IL (2) | IL158728A0 (sl) |
MX (1) | MXPA04000230A (sl) |
NO (1) | NO20040065L (sl) |
PL (1) | PL366841A1 (sl) |
PT (1) | PT1406894E (sl) |
RU (1) | RU2273639C2 (sl) |
SI (1) | SI1406894T1 (sl) |
UA (1) | UA75425C2 (sl) |
WO (1) | WO2003006459A1 (sl) |
ZA (1) | ZA200308782B (sl) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2550361C (en) | 2003-12-19 | 2014-04-29 | Prabha Ibrahim | Compounds and methods for development of ret modulators |
US7498342B2 (en) | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
KR100616099B1 (ko) * | 2004-09-20 | 2006-08-28 | 한국과학기술연구원 | T-타입 칼슘채널 길항제로 유효한 신규 피페라지닐알킬이소옥사졸 유도체 |
MX2007014377A (es) | 2005-05-17 | 2008-02-06 | Plexxikon Inc | Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina. |
BRPI0611863B1 (pt) | 2005-06-22 | 2021-11-23 | Plexxikon, Inc | Composto, bem como composição e kit compreendendo o mesmo, composto intermediário na preparação do mesmo, método para tratamento e uso do mesmo |
WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
US20100168197A1 (en) * | 2007-02-28 | 2010-07-01 | Naresh Kumar | Muscarinic receptor antagonists |
EP2170830B1 (en) | 2007-07-17 | 2014-10-15 | Plexxikon, Inc. | 2-FLUORO-BENZENESULFONAMIDE COMPOUNDS AS Raf KINASE MODULATORS |
MY172424A (en) | 2009-04-03 | 2019-11-25 | Hoffmann La Roche | Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof |
BR112012012156A2 (pt) | 2009-11-06 | 2015-09-08 | Plexxikon Inc | compostos e métodos para modulação de cinase, e indicações para esta |
TR201816421T4 (tr) | 2011-02-07 | 2018-11-21 | Plexxikon Inc | Kinaz modülasyonu için bileşikler ve metotlar ve bunların endikasyonları. |
AR085279A1 (es) | 2011-02-21 | 2013-09-18 | Plexxikon Inc | Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico |
US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
CN104958297A (zh) * | 2015-06-03 | 2015-10-07 | 周玉梅 | 一种用于麻醉镇静催眠的药物组合物及其应用 |
CN110615774B (zh) * | 2019-09-19 | 2022-11-11 | 安徽中医药大学 | 具有抗炎活性的苄基哌嗪类化合物、制法及医药用途 |
JP2022090346A (ja) | 2020-12-07 | 2022-06-17 | 三星電子株式会社 | 共重合体、ならびに当該共重合体を用いるエレクトロルミネッセンス素子材料およびエレクトロルミネッセンス素子 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL111730A (en) * | 1993-11-29 | 1998-12-06 | Fujisawa Pharmaceutical Co | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them |
DE69629023T2 (de) | 1995-05-02 | 2004-04-22 | Schering Corp. | Piperazino-derivative als neurokininantagonisten |
US5696267A (en) * | 1995-05-02 | 1997-12-09 | Schering Corporation | Substituted oximes, hydrazones and olefins as neurokinin antagonists |
AU706021B2 (en) | 1995-05-25 | 1999-06-03 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives |
US6087357A (en) | 1995-12-18 | 2000-07-11 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives as tachykinin antagonists |
JP4189043B2 (ja) | 1996-09-30 | 2008-12-03 | 株式会社資生堂 | N−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤 |
AUPO735997A0 (en) * | 1997-06-17 | 1997-07-10 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives |
DE59814233D1 (de) * | 1997-08-27 | 2008-07-03 | Solvay Pharm Gmbh | Indolmethyl-N,N'-bisacylpiperazine als Neurokininrezeptorantagonisten |
DE19824865A1 (de) * | 1997-08-27 | 1999-03-04 | Solvay Pharm Gmbh | Neue Harnstoffderivate |
JP4370059B2 (ja) | 1998-12-23 | 2009-11-25 | シェーリング コーポレイション | ニューロキニンアンタゴニストとしての置換オキシムおよびヒドラゾン |
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2002
- 2002-03-07 UA UA2004020930A patent/UA75425C2/uk unknown
- 2002-07-03 CN CNB028127307A patent/CN1223591C/zh not_active Expired - Fee Related
- 2002-07-03 MX MXPA04000230A patent/MXPA04000230A/es active IP Right Grant
- 2002-07-03 KR KR1020047000273A patent/KR100900889B1/ko not_active IP Right Cessation
- 2002-07-03 PL PL02366841A patent/PL366841A1/xx not_active Application Discontinuation
- 2002-07-03 RU RU2003136264/04A patent/RU2273639C2/ru not_active IP Right Cessation
- 2002-07-03 IL IL15872802A patent/IL158728A0/xx unknown
- 2002-07-03 DE DE60202371T patent/DE60202371T2/de not_active Expired - Fee Related
- 2002-07-03 WO PCT/EP2002/007472 patent/WO2003006459A1/en active IP Right Grant
- 2002-07-03 US US10/480,542 patent/US7094779B2/en not_active Expired - Fee Related
- 2002-07-03 DK DK02784838T patent/DK1406894T3/da active
- 2002-07-03 SI SI200230060T patent/SI1406894T1/sl unknown
- 2002-07-03 EP EP02784838A patent/EP1406894B1/en not_active Expired - Lifetime
- 2002-07-03 AT AT02784838T patent/ATE285407T1/de not_active IP Right Cessation
- 2002-07-03 JP JP2003512231A patent/JP3765543B2/ja not_active Expired - Fee Related
- 2002-07-03 AU AU2002333229A patent/AU2002333229B2/en not_active Ceased
- 2002-07-03 ES ES02784838T patent/ES2230521T3/es not_active Expired - Lifetime
- 2002-07-03 PT PT02784838T patent/PT1406894E/pt unknown
- 2002-07-03 HU HU0401093A patent/HUP0401093A3/hu unknown
- 2002-07-03 BR BR0210080-0A patent/BR0210080A/pt not_active IP Right Cessation
- 2002-07-03 CA CA002446726A patent/CA2446726A1/en not_active Abandoned
- 2002-07-04 AR ARP020102505A patent/AR034722A1/es unknown
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2003
- 2003-11-03 IL IL158728A patent/IL158728A/en active IP Right Grant
- 2003-11-10 HR HR20030912A patent/HRP20030912A2/xx not_active Application Discontinuation
- 2003-11-11 ZA ZA200308782A patent/ZA200308782B/en unknown
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2004
- 2004-01-08 NO NO20040065A patent/NO20040065L/no not_active Application Discontinuation
- 2004-12-14 HK HK04109874A patent/HK1067364A1/xx not_active IP Right Cessation
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