UA75365C2 - Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon - Google Patents

Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon Download PDF

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Publication number
UA75365C2
UA75365C2 UA2003032259A UA2003032259A UA75365C2 UA 75365 C2 UA75365 C2 UA 75365C2 UA 2003032259 A UA2003032259 A UA 2003032259A UA 2003032259 A UA2003032259 A UA 2003032259A UA 75365 C2 UA75365 C2 UA 75365C2
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UA
Ukraine
Prior art keywords
temperature
hours
specified
mixture
crystalline
Prior art date
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UA2003032259A
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English (en)
Ukrainian (uk)
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Bristol Myers Squibb Co
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22845469&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA75365(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of UA75365C2 publication Critical patent/UA75365C2/uk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
UA2003032259A 2000-08-16 2001-01-08 Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon UA75365C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22559000P 2000-08-16 2000-08-16
PCT/US2001/024540 WO2002014323A2 (en) 2000-08-16 2001-08-01 Polymorphs of an epothilone analog

Publications (1)

Publication Number Publication Date
UA75365C2 true UA75365C2 (en) 2006-04-17

Family

ID=22845469

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2003032259A UA75365C2 (en) 2000-08-16 2001-01-08 Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon

Country Status (42)

Country Link
US (4) US6689802B2 (sl)
EP (1) EP1309597B1 (sl)
JP (1) JP5046467B2 (sl)
KR (1) KR100810342B1 (sl)
CN (1) CN1269821C (sl)
AR (1) AR034259A1 (sl)
AT (1) ATE366735T1 (sl)
AU (2) AU2001281082B2 (sl)
BG (1) BG66132B1 (sl)
BR (1) BR0113234A (sl)
CA (1) CA2418109C (sl)
CY (1) CY1107758T1 (sl)
CZ (1) CZ305523B6 (sl)
DE (1) DE60129334T2 (sl)
DK (1) DK1309597T3 (sl)
EE (1) EE05273B1 (sl)
ES (1) ES2288518T3 (sl)
GE (1) GEP20053495B (sl)
HK (1) HK1052010A1 (sl)
HR (1) HRP20030190B1 (sl)
HU (1) HU229314B1 (sl)
IL (2) IL153993A0 (sl)
IS (1) IS2845B (sl)
LT (1) LT5138B (sl)
LV (1) LV13032B (sl)
MX (1) MXPA03001431A (sl)
MY (1) MY134129A (sl)
NO (1) NO328500B1 (sl)
NZ (1) NZ523722A (sl)
PE (1) PE20020290A1 (sl)
PL (1) PL205628B1 (sl)
PT (1) PT1309597E (sl)
RO (1) RO123296B1 (sl)
RU (1) RU2272039C2 (sl)
SI (1) SI21100B (sl)
SK (1) SK287876B6 (sl)
TW (1) TWI320040B (sl)
UA (1) UA75365C2 (sl)
UY (1) UY26886A1 (sl)
WO (1) WO2002014323A2 (sl)
YU (1) YU12103A (sl)
ZA (1) ZA200300522B (sl)

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EP3564259A3 (en) 2012-11-09 2020-02-12 Innate Pharma Recognition tags for tgase-mediated conjugation
CN103183681B (zh) * 2013-03-06 2016-01-13 浙江海正药业股份有限公司 伊沙匹隆的新晶型及其制备方法
US10611824B2 (en) 2013-03-15 2020-04-07 Innate Pharma Solid phase TGase-mediated conjugation of antibodies
EP3010547B1 (en) 2013-06-20 2021-04-21 Innate Pharma Enzymatic conjugation of polypeptides
WO2014202775A1 (en) 2013-06-21 2014-12-24 Innate Pharma Enzymatic conjugation of polypeptides
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CN112409366A (zh) * 2020-11-30 2021-02-26 湖北宏中药业股份有限公司 一种伊沙匹隆二聚体的高收率制备方法
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Also Published As

Publication number Publication date
PE20020290A1 (es) 2002-04-03
US20020188014A1 (en) 2002-12-12
EE05273B1 (et) 2010-02-15
LT2003017A (en) 2004-03-25
TWI320040B (en) 2010-02-01
EP1309597B1 (en) 2007-07-11
HK1052010A1 (en) 2003-08-29
BG107467A (bg) 2003-09-30
NO20030707D0 (no) 2003-02-14
US7153879B2 (en) 2006-12-26
SK1342003A3 (en) 2003-09-11
KR20030022411A (ko) 2003-03-15
PT1309597E (pt) 2007-08-22
JP2004506638A (ja) 2004-03-04
HUP0300826A2 (hu) 2003-09-29
AU2001281082B2 (en) 2007-01-04
RO123296B1 (ro) 2011-06-30
ATE366735T1 (de) 2007-08-15
LV13032B (en) 2003-12-20
MXPA03001431A (es) 2004-05-04
CA2418109C (en) 2011-09-27
IS6714A (is) 2003-02-11
ES2288518T3 (es) 2008-01-16
IL153993A0 (en) 2003-07-31
PL365610A1 (en) 2005-01-10
CN1468243A (zh) 2004-01-14
IS2845B (is) 2013-08-15
SI21100B (sl) 2009-12-31
KR100810342B1 (ko) 2008-03-07
EE200300063A (et) 2004-12-15
CZ305523B6 (cs) 2015-11-18
BR0113234A (pt) 2004-02-25
BG66132B1 (bg) 2011-06-30
NO328500B1 (no) 2010-03-01
US6689802B2 (en) 2004-02-10
HUP0300826A3 (en) 2005-05-30
IL153993A (en) 2009-07-20
ZA200300522B (en) 2004-04-20
US6982276B2 (en) 2006-01-03
HRP20030190A2 (en) 2003-04-30
EP1309597A2 (en) 2003-05-14
JP5046467B2 (ja) 2012-10-10
DE60129334T2 (de) 2008-04-03
WO2002014323A2 (en) 2002-02-21
HRP20030190B1 (en) 2011-07-31
HU229314B1 (en) 2013-10-28
AR034259A1 (es) 2004-02-18
DE60129334D1 (en) 2007-08-23
US20060063815A1 (en) 2006-03-23
PL205628B1 (pl) 2010-05-31
YU12103A (sh) 2006-08-17
AU8108201A (en) 2002-02-25
CN1269821C (zh) 2006-08-16
GEP20053495B (en) 2005-04-25
UY26886A1 (es) 2002-03-22
US20040157897A1 (en) 2004-08-12
CZ2003418A3 (cs) 2004-01-14
CY1107758T1 (el) 2013-06-19
LT5138B (lt) 2004-06-25
NO20030707L (no) 2003-04-15
WO2002014323A3 (en) 2002-05-02
CA2418109A1 (en) 2002-02-21
SI21100A (sl) 2003-06-30
MY134129A (en) 2007-11-30
NZ523722A (en) 2005-04-29
SK287876B6 (sk) 2012-02-03
USRE39251E1 (en) 2006-08-29
DK1309597T3 (da) 2007-10-22
RU2272039C2 (ru) 2006-03-20

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