UA61066C2 - A METHOD FOR OBTAINING THE FOREIGN PROTEIN IN CELLS OF à.cÄLI, A PLASMID VECTOR AND TRANSFORMED STRAIN OF E. COLI FOR EXPRESSION OF THE FOREIGN PROTEIN - Google Patents
A METHOD FOR OBTAINING THE FOREIGN PROTEIN IN CELLS OF à.cÄLI, A PLASMID VECTOR AND TRANSFORMED STRAIN OF E. COLI FOR EXPRESSION OF THE FOREIGN PROTEIN Download PDFInfo
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- UA61066C2 UA61066C2 UA98073658A UA98073658A UA61066C2 UA 61066 C2 UA61066 C2 UA 61066C2 UA 98073658 A UA98073658 A UA 98073658A UA 98073658 A UA98073658 A UA 98073658A UA 61066 C2 UA61066 C2 UA 61066C2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95119478 | 1995-12-11 | ||
| PCT/EP1996/005260 WO1997021829A1 (de) | 1995-12-11 | 1996-11-28 | Verfahren zur herstellung von rekombinanten proteinen in e. coli mittels hochzelldichte-fermentation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA61066C2 true UA61066C2 (en) | 2003-11-17 |
Family
ID=8219878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA98073658A UA61066C2 (en) | 1995-12-11 | 1996-11-28 | A METHOD FOR OBTAINING THE FOREIGN PROTEIN IN CELLS OF à.cÄLI, A PLASMID VECTOR AND TRANSFORMED STRAIN OF E. COLI FOR EXPRESSION OF THE FOREIGN PROTEIN |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6410270B1 (es) |
| EP (1) | EP0866876B1 (es) |
| JP (2) | JP4101879B2 (es) |
| KR (1) | KR100444735B1 (es) |
| CN (1) | CN1117160C (es) |
| AR (1) | AR005035A1 (es) |
| AT (1) | ATE213271T1 (es) |
| AU (1) | AU716612B2 (es) |
| BR (1) | BR9611937A (es) |
| CA (1) | CA2240097C (es) |
| CZ (1) | CZ291415B6 (es) |
| DE (1) | DE59608743D1 (es) |
| DK (1) | DK0866876T3 (es) |
| ES (1) | ES2171752T3 (es) |
| HU (1) | HU227945B1 (es) |
| NO (1) | NO319090B1 (es) |
| PL (1) | PL185665B1 (es) |
| PT (1) | PT866876E (es) |
| RU (1) | RU2201455C2 (es) |
| SI (1) | SI0866876T1 (es) |
| SK (1) | SK283169B6 (es) |
| UA (1) | UA61066C2 (es) |
| WO (1) | WO1997021829A1 (es) |
| ZA (1) | ZA9610384B (es) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9715895D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
| AU1223600A (en) | 1998-10-28 | 2000-05-15 | Genentech Inc. | Process |
| ATE426674T1 (de) | 2000-11-03 | 2009-04-15 | Genentech Inc | Stoffwechselanderungen in garungen zur produktion rekombinanter proteine |
| PT1407052E (pt) * | 2001-07-06 | 2009-03-05 | Merck Patent Gmbh | Método para a expressão melhorada de proteínas em bactérias por monitorização e modulação da dobragem das proteínas |
| EP1706490A4 (en) * | 2003-12-12 | 2008-02-27 | Conjugon Inc | STRICTLY REGULATED GENE EXPRESSION SYSTEMS |
| DE60332667D1 (de) * | 2003-12-23 | 2010-07-01 | Council Scient Ind Res | Verfahren zur herstellung von streptokinase durch kultivierung von genetisch veränderten escherichia coli |
| CA2592390A1 (en) | 2004-12-22 | 2006-06-29 | Genentech, Inc. | Methods for producing soluble multi-membrane-spanning proteins |
| CN105463045A (zh) * | 2006-07-27 | 2016-04-06 | 惠氏公司 | 用于生产重组蛋白质的高细胞密度补料-分批发酵方法 |
| US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
| SG10201510384UA (en) | 2006-09-13 | 2016-01-28 | Abbvie Inc | Cell culture improvements |
| MX2011002638A (es) | 2008-09-15 | 2011-04-05 | Genentech Inc | Composiciones y metodos para regular osmolaridad celular. |
| CN102471787B (zh) * | 2009-07-28 | 2016-01-20 | 三井化学株式会社 | 乳酸制造方法 |
| KR101858598B1 (ko) * | 2010-02-01 | 2018-05-16 | 디그나 비오테크, 에스.엘. | 인터페론 알파 5의 제조방법 |
| WO2012028522A1 (en) * | 2010-08-30 | 2012-03-08 | F. Hoffmann-La Roche Ag | Alkaline feed |
| KR101252150B1 (ko) * | 2010-11-18 | 2013-04-08 | 한국과학기술원 | 재조합 ＤＮＡ 분자 클로닝을 위한 알데히드 환원효소 ＹｑｈＤ 유전자를 포함하는 자살 벡터 |
| RU2507736C2 (ru) * | 2011-01-11 | 2014-02-27 | Федеральное государственное бюджетное учреждение науки Институт биологии гена Российской академии наук (ИБГ РАН) | Способ создания трансгенных растений с высоким уровнем экспрессии трансгенного белка |
| EP2702077A2 (en) | 2011-04-27 | 2014-03-05 | AbbVie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| RU2496877C2 (ru) * | 2011-12-15 | 2013-10-27 | Общество с ограниченной ответственностью "Лаборатория медицинской биотехнологии" (ООО "ЛМБТ") | ПЛАЗМИДНЫЙ ВЕКТОР pHYP С ПОВЫШЕННОЙ СЕГРЕГАЦИОННОЙ СТАБИЛЬНОСТЬЮ ДЛЯ ЭКСПРЕССИИ РЕКОМБИНАНТНОГО БЕЛКА, БАКТЕРИЯ - ПРОДУЦЕНТ ПРЕДШЕСТВЕННИКА РЕКОМБИНАНТНОГО БЕЛКА И СПОСОБ ПОЛУЧЕНИЯ РЕКОМБИНАНТНОГО БЕЛКА |
| WO2013124474A2 (en) | 2012-02-23 | 2013-08-29 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| WO2013137622A1 (en) * | 2012-03-12 | 2013-09-19 | Hanmi Science Co., Ltd. | Method of culturing e. coli cells for high density |
| CN102604904B (zh) * | 2012-03-14 | 2013-09-18 | 苏州汉酶生物技术有限公司 | 一种葡萄糖脱氢酶的生产方法 |
| WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| US9150645B2 (en) | 2012-04-20 | 2015-10-06 | Abbvie, Inc. | Cell culture methods to reduce acidic species |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| US9206390B2 (en) | 2012-09-02 | 2015-12-08 | Abbvie, Inc. | Methods to control protein heterogeneity |
| US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
| SG10201709131UA (en) | 2013-03-08 | 2017-12-28 | Genzyme Corp | Continuous purification of therapeutic proteins |
| CA2905010A1 (en) | 2013-03-12 | 2014-09-18 | Abbvie Inc. | Human antibodies that bind human tnf-alpha and methods of preparing the same |
| US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
| WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
| WO2014159579A1 (en) | 2013-03-14 | 2014-10-02 | Abbvie Inc. | MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE |
| EP3052640A2 (en) | 2013-10-04 | 2016-08-10 | AbbVie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
| US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
| WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
| TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
| TWI671312B (zh) | 2014-01-17 | 2019-09-11 | 美商健臻公司 | 無菌層析法及製法 |
| US9714273B2 (en) * | 2014-10-08 | 2017-07-25 | Utah State University | Expression systems and associated methods |
| MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
| CN111032850B (zh) | 2017-04-27 | 2024-08-13 | 朱诺治疗学有限公司 | 寡聚粒子试剂及其使用方法 |
| AU2019332764A1 (en) | 2018-08-31 | 2021-05-06 | Genzyme Corporation | Sterile chromatography resin and use thereof in manufacturing processes |
| CN110684101A (zh) * | 2019-11-15 | 2020-01-14 | 上海松皓生物科技有限公司 | 一种重组水蛭素的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3854306B2 (ja) | 1991-03-06 | 2006-12-06 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | ヒト化及びキメラモノクローナル抗体 |
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1996
- 1996-11-12 AR ARP960105609A patent/AR005035A1/es unknown
- 1996-11-28 RU RU98113062/13A patent/RU2201455C2/ru not_active IP Right Cessation
- 1996-11-28 BR BR9611937A patent/BR9611937A/pt not_active Application Discontinuation
- 1996-11-28 WO PCT/EP1996/005260 patent/WO1997021829A1/de active IP Right Grant
- 1996-11-28 ES ES96941047T patent/ES2171752T3/es not_active Expired - Lifetime
- 1996-11-28 SK SK740-98A patent/SK283169B6/sk not_active IP Right Cessation
- 1996-11-28 DE DE59608743T patent/DE59608743D1/de not_active Expired - Lifetime
- 1996-11-28 HU HU0000317A patent/HU227945B1/hu not_active IP Right Cessation
- 1996-11-28 AU AU10325/97A patent/AU716612B2/en not_active Ceased
- 1996-11-28 CA CA002240097A patent/CA2240097C/en not_active Expired - Fee Related
- 1996-11-28 EP EP96941047A patent/EP0866876B1/de not_active Expired - Lifetime
- 1996-11-28 CN CN96198949A patent/CN1117160C/zh not_active Expired - Fee Related
- 1996-11-28 AT AT96941047T patent/ATE213271T1/de active
- 1996-11-28 UA UA98073658A patent/UA61066C2/uk unknown
- 1996-11-28 PL PL96327188A patent/PL185665B1/pl not_active IP Right Cessation
- 1996-11-28 CZ CZ19981652A patent/CZ291415B6/cs not_active IP Right Cessation
- 1996-11-28 JP JP52166297A patent/JP4101879B2/ja not_active Expired - Fee Related
- 1996-11-28 SI SI9630466T patent/SI0866876T1/xx unknown
- 1996-11-28 PT PT96941047T patent/PT866876E/pt unknown
- 1996-11-28 US US09/077,549 patent/US6410270B1/en not_active Expired - Lifetime
- 1996-11-28 DK DK96941047T patent/DK0866876T3/da active
- 1996-11-28 KR KR10-1998-0704331A patent/KR100444735B1/ko not_active IP Right Cessation
- 1996-12-10 ZA ZA9610384A patent/ZA9610384B/xx unknown
-
1998
- 1998-06-10 NO NO19982672A patent/NO319090B1/no not_active IP Right Cessation
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2007
- 2007-04-18 JP JP2007109443A patent/JP4102422B2/ja not_active Expired - Fee Related
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