ATE426674T1 - Stoffwechselanderungen in garungen zur produktion rekombinanter proteine - Google Patents

Stoffwechselanderungen in garungen zur produktion rekombinanter proteine

Info

Publication number
ATE426674T1
ATE426674T1 AT01987201T AT01987201T ATE426674T1 AT E426674 T1 ATE426674 T1 AT E426674T1 AT 01987201 T AT01987201 T AT 01987201T AT 01987201 T AT01987201 T AT 01987201T AT E426674 T1 ATE426674 T1 AT E426674T1
Authority
AT
Austria
Prior art keywords
host cells
recombinant host
polypeptide
cookings
production
Prior art date
Application number
AT01987201T
Other languages
English (en)
Inventor
Dana Andersen
John Joly
Bradley Snedecor
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22928808&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE426674(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE426674T1 publication Critical patent/ATE426674T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fertilizers (AREA)
AT01987201T 2000-11-03 2001-11-01 Stoffwechselanderungen in garungen zur produktion rekombinanter proteine ATE426674T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24596200P 2000-11-03 2000-11-03

Publications (1)

Publication Number Publication Date
ATE426674T1 true ATE426674T1 (de) 2009-04-15

Family

ID=22928808

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01987201T ATE426674T1 (de) 2000-11-03 2001-11-01 Stoffwechselanderungen in garungen zur produktion rekombinanter proteine

Country Status (14)

Country Link
US (1) US6716602B2 (de)
EP (1) EP1332222B1 (de)
JP (1) JP4878724B2 (de)
AT (1) ATE426674T1 (de)
AU (1) AU3944002A (de)
CA (1) CA2426100A1 (de)
CY (1) CY1110494T1 (de)
DE (1) DE60138127D1 (de)
DK (1) DK1332222T3 (de)
ES (1) ES2324645T3 (de)
HK (1) HK1054765A1 (de)
IL (2) IL155482A0 (de)
PT (1) PT1332222E (de)
WO (1) WO2002040697A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7294481B1 (en) 1999-01-05 2007-11-13 Immunex Corporation Method for producing recombinant proteins
ATE367436T1 (de) * 2002-05-30 2007-08-15 Natureworks Llc Verfahren und materialien zur produktion von d- milchsäure in hefe
GB0321100D0 (en) * 2003-09-09 2003-10-08 Celltech R&D Ltd Biological products
US20110269233A1 (en) 2008-09-15 2011-11-03 Laetitia Malphettes Compositions and methods for regulating cell osmolarity
US20110117087A1 (en) 2009-10-26 2011-05-19 Reinhard Franze Method for the production of a glycosylated immunoglobulin
GB2482536B (en) * 2010-08-05 2013-07-24 Hera Pharmaceuticals Inc Expression of antibody or a fragment thereof in lactobacillus
EP2898086B1 (de) 2012-09-19 2018-11-14 F.Hoffmann-La Roche Ag Verfahren und zusammensetzungen zur verhinderung von norleucin-fehlinkorporation in proteine
BR112016002494A2 (pt) 2013-08-05 2017-09-05 Greenlight Biosciences Inc Proteí-nas construídas com um sítio de clivagem de protease, ácido nucléico, vetor, célula e processo de engenharia de uma proteína recombinante e de um grande número de variantes de ácidos nucleicos que codificam proteínas recombinantes
JPWO2015178466A1 (ja) * 2014-05-21 2017-04-20 味の素株式会社 フィブロイン様タンパク質の製造法
CN104164465B (zh) * 2014-07-14 2017-07-04 北京泰德制药股份有限公司 一种表达重组蛋白的发酵工艺
MX2017005930A (es) * 2014-11-05 2017-06-30 Genentech Inc Metodo de produccion de proteinas de cadena doble en bacterias.
WO2016073794A1 (en) 2014-11-05 2016-05-12 Genentech, Inc. Methods of producing two chain proteins in bacteria
JP2018516081A (ja) 2015-05-29 2018-06-21 カーギル・インコーポレイテッド 配糖体を産生するための熱処理
US10815513B2 (en) 2015-05-29 2020-10-27 Cargill, Incorporated Fermentation methods for producing steviol glycosides using high pH and compositions obtained therefrom
CA2987630A1 (en) * 2015-05-29 2016-12-08 Cargill, Incorporated Fermentation methods for producing steviol glycosides with multi-phase feeding
JP2018521680A (ja) 2015-08-06 2018-08-09 カーギル・インコーポレイテッド ステビオール配糖体を生成するための発酵法
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
US11261462B2 (en) 2016-01-27 2022-03-01 Just-Evotec Biologics, Inc. Inducible expression from transposon-based vectors and uses
US11098310B2 (en) 2016-01-27 2021-08-24 Just-Evotec Biologics, Inc. Expression from transposon-based vectors and uses
WO2017132376A1 (en) 2016-01-27 2017-08-03 Just Biotherapeutics, Inc. Hybrid promoter and uses thereof
CN111032850A (zh) 2017-04-27 2020-04-17 朱诺治疗学有限公司 寡聚粒子试剂及其使用方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565785A (en) 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
US4673641A (en) 1982-12-16 1987-06-16 Molecular Genetics Research And Development Limited Partnership Co-aggregate purification of proteins
US4710473A (en) 1983-08-10 1987-12-01 Amgen, Inc. DNA plasmids
US4738921A (en) 1984-09-27 1988-04-19 Eli Lilly And Company Derivative of the tryptophan operon for expression of fused gene products
US4795706A (en) 1985-01-31 1989-01-03 Eli Lilly And Company Novel expression control sequences
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5342763A (en) 1992-11-23 1994-08-30 Genentech, Inc. Method for producing polypeptide via bacterial fermentation
CA2153445C (en) * 1994-09-08 2002-05-21 Ashok Raj Saxena Video optimized media streamer user interface
US5789199A (en) * 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5639635A (en) 1994-11-03 1997-06-17 Genentech, Inc. Process for bacterial production of polypeptides
US5790423A (en) * 1995-06-14 1998-08-04 Audible, Inc. Interactive audio transmission receiving and playback system
AR005035A1 (es) 1995-12-11 1999-04-07 Merck Patent Ges Mit Beschränkter Haftung Procedimiento para preparar proteinas recombinantes en e. coli, mediante fermentacion con gran concentracion de celulas.
US6615192B1 (en) * 1999-03-12 2003-09-02 Matsushita Electric Industrial Co., Ltd. Contents copying system, copying method, computer-readable recording medium and disc drive copying contents but not a cipher key via a host computer
BR0006882B1 (pt) * 1999-05-28 2014-03-18 Panasonic Corp Cartão de memória semicondutora, aparelho de execução, aparelho de gravação, método de execução, método de gravação e meio de gravação que pode ser lido por computador
DE19943919B4 (de) * 1999-09-14 2004-05-27 Pharmacia Ab Verfahren zur Steigerung der Ausbeute von rekombinanten Proteinen in mikrobiellen Fermentationsprozessen

Also Published As

Publication number Publication date
DE60138127D1 (de) 2009-05-07
EP1332222B1 (de) 2009-03-25
AU3944002A (en) 2002-05-27
CA2426100A1 (en) 2002-05-23
PT1332222E (pt) 2009-06-30
IL155482A0 (en) 2003-11-23
WO2002040697A2 (en) 2002-05-23
JP4878724B2 (ja) 2012-02-15
CY1110494T1 (el) 2015-04-29
ES2324645T3 (es) 2009-08-12
IL155482A (en) 2010-12-30
WO2002040697A3 (en) 2003-03-13
US6716602B2 (en) 2004-04-06
JP2004517614A (ja) 2004-06-17
DK1332222T3 (da) 2009-07-06
HK1054765A1 (en) 2003-12-12
US20020164700A1 (en) 2002-11-07
EP1332222A2 (de) 2003-08-06

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