TWI755350B - 用於多工偵測與眼科病況有關的對偶基因之方法 - Google Patents

用於多工偵測與眼科病況有關的對偶基因之方法 Download PDF

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TWI755350B
TWI755350B TW103139861A TW103139861A TWI755350B TW I755350 B TWI755350 B TW I755350B TW 103139861 A TW103139861 A TW 103139861A TW 103139861 A TW103139861 A TW 103139861A TW I755350 B TWI755350 B TW I755350B
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detection
sequence
nucleotide
probes
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TW201610167A (zh
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蕾 趙
趙善英
李津
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美商阿韋利諾美國實驗有限公司
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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TW103139861A 2013-11-15 2014-11-17 用於多工偵測與眼科病況有關的對偶基因之方法 TWI755350B (zh)

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US201361905051P 2013-11-15 2013-11-15
US61/905,051 2013-11-15

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TW103139861A TWI755350B (zh) 2013-11-15 2014-11-17 用於多工偵測與眼科病況有關的對偶基因之方法
TW111108208A TWI812047B (zh) 2013-11-15 2014-11-17 用於多工偵測與眼科病況有關的對偶基因之方法
TW112128794A TW202346604A (zh) 2013-11-15 2014-11-17 用於多工偵測與眼科病況有關的對偶基因之方法

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TW112128794A TW202346604A (zh) 2013-11-15 2014-11-17 用於多工偵測與眼科病況有關的對偶基因之方法

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US (2) US11525160B2 (OSRAM)
EP (2) EP3872192A1 (OSRAM)
JP (2) JP6672147B2 (OSRAM)
KR (3) KR20230007558A (OSRAM)
CN (2) CN105899681B (OSRAM)
AU (2) AU2014348279B2 (OSRAM)
SG (1) SG10201804076RA (OSRAM)
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JP6412101B2 (ja) * 2013-03-15 2018-10-24 アベリノ ラボ ユーエスエー インコーポレイテッドＡｖｅｌｌｉｎｏ Ｌａｂ ＵＳＡ， Ｉｎｃ． アレル検出用ゲノムｄｎａテンプレートの改良された単離方法
US10889850B2 (en) 2013-03-15 2021-01-12 Avellino Lab Usa, Inc. Methods for improved isolation of genomic DNA templates for allele detection
CN105899681B (zh) 2013-11-15 2021-06-22 阿维利诺美国实验室股份有限公司 用于与眼科状况有关的等位基因的多重检测的方法
ES2905558T3 (es) 2015-11-13 2022-04-11 Avellino Lab Usa Inc Procedimientos para el tratamiento de las distrofias corneales
CN106480200A (zh) * 2016-10-25 2017-03-08 北京亿昊基因技术有限公司 一种快速高效的与角膜营养不良相关基因突变位点的检测方法
CN108085375B (zh) * 2016-11-07 2020-10-16 北京华大通瀛科技有限公司 检测角膜营养不良基因多态性位点的基因型的方法及其试剂盒
AU2018250570A1 (en) 2017-04-10 2019-11-21 Avellino Lab Usa, Inc. Methods for multiplex detection of alleles associated with corneal dystrophy
CN107523635A (zh) * 2017-10-09 2017-12-29 湖南大地同年生物科技有限公司 一种tgfbi基因多态性快速检测试剂盒及其检测方法
CN107858420A (zh) * 2017-11-17 2018-03-30 奥斯汀生命科学技术公司 用于诊断人TGFβI基因124位点变异引起角膜营养不良的引物探针及检测方法
KR200487603Y1 (ko) 2018-02-01 2018-12-05 백병하 선풍기용 공기정화기구
CN108796062A (zh) * 2018-06-06 2018-11-13 无锡正则精准医学检验有限公司 一种检测tgfbi基因多态性的试剂盒
CN109406469B (zh) * 2018-10-24 2021-04-09 中国医科大学 基于蛋白结合诱导dna双链变构的检测色氨酸的方法
KR102241836B1 (ko) * 2019-06-14 2021-04-21 솔젠트 (주) 듀얼 체크 올리고를 이용한 유전자 다형성 검사 방법
CN113088569A (zh) * 2020-01-09 2021-07-09 北京中因科技有限公司 一种多重荧光定量pcr试剂盒
CN113999899A (zh) * 2020-07-28 2022-02-01 首都医科大学附属北京同仁医院 一种检测tgfbi基因突变的试剂盒
CN115820837A (zh) * 2022-11-04 2023-03-21 温州谱希基因科技有限公司 一种角膜营养不良的pcr检测试剂盒及其应用
CN118222692A (zh) * 2022-12-21 2024-06-21 北京中因医学检验实验室有限公司 一种人tgfbi基因分型检测的引物探针组合物及其应用
CN117417997B (zh) * 2023-10-26 2025-07-29 上海谱希和光基因科技有限公司 一种诊断圆锥角膜的基因组生物标志物组合
TWI879353B (zh) * 2023-12-27 2025-04-01 台南應用科技大學 兩對交叉引子的多目標設計方法

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WO2015073978A9 (en) 2016-06-23
AU2014348279A9 (en) 2016-07-28
JP2017501685A (ja) 2017-01-19
WO2015073978A2 (en) 2015-05-21
TW202346604A (zh) 2023-12-01
TWI812047B (zh) 2023-08-11
AU2014348279A1 (en) 2016-06-09
US20160319357A1 (en) 2016-11-03
EP3068908B1 (en) 2021-01-06
US20230348984A1 (en) 2023-11-02
CN105899681B (zh) 2021-06-22
JP6672147B2 (ja) 2020-03-25
AU2021202884B2 (en) 2023-04-06
KR102293785B1 (ko) 2021-08-26
JP2020039339A (ja) 2020-03-19
KR102483783B1 (ko) 2022-12-30
US11525160B2 (en) 2022-12-13
AU2014348279B2 (en) 2021-02-18
EP3068908A4 (en) 2017-08-23
KR20160079117A (ko) 2016-07-05
EP3068908A2 (en) 2016-09-21
CN113604551A (zh) 2021-11-05
SG10201804076RA (en) 2018-06-28
KR20210099204A (ko) 2021-08-11
CN105899681A (zh) 2016-08-24
WO2015073978A3 (en) 2015-07-16
EP3872192A1 (en) 2021-09-01
TW202223098A (zh) 2022-06-16
KR20230007558A (ko) 2023-01-12
AU2021202884A1 (en) 2021-06-03
JP7077289B2 (ja) 2022-05-30
TW201610167A (zh) 2016-03-16

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