JP6672147B2 - 眼疾患に関連したアレルのマルチプレックス検出方法 - Google Patents

眼疾患に関連したアレルのマルチプレックス検出方法 Download PDF

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JP6672147B2
JP6672147B2 JP2016531678A JP2016531678A JP6672147B2 JP 6672147 B2 JP6672147 B2 JP 6672147B2 JP 2016531678 A JP2016531678 A JP 2016531678A JP 2016531678 A JP2016531678 A JP 2016531678A JP 6672147 B2 JP6672147 B2 JP 6672147B2
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detection
seq
probes
tgfβi gene
nucleotide sequence
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JP2017501685A (ja
JP2017501685A5 (OSRAM
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シェーン，コニー チャオ
シェーン，コニー チャオ
チョ，スンヨン
イ，ジン
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Avellino Lab USA Inc
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
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JP2016531678A 2013-11-15 2014-11-17 眼疾患に関連したアレルのマルチプレックス検出方法 Expired - Fee Related JP6672147B2 (ja)

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US201361905051P 2013-11-15 2013-11-15
US61/905,051 2013-11-15
PCT/US2014/065975 WO2015073978A2 (en) 2013-11-15 2014-11-17 Methods for multiplex detection of alleles associated with ophthalmic conditions

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JP2017501685A JP2017501685A (ja) 2017-01-19
JP2017501685A5 JP2017501685A5 (OSRAM) 2017-12-28
JP6672147B2 true JP6672147B2 (ja) 2020-03-25

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US (2) US11525160B2 (OSRAM)
EP (2) EP3872192A1 (OSRAM)
JP (2) JP6672147B2 (OSRAM)
KR (3) KR20230007558A (OSRAM)
CN (2) CN105899681B (OSRAM)
AU (2) AU2014348279B2 (OSRAM)
SG (1) SG10201804076RA (OSRAM)
TW (3) TWI755350B (OSRAM)
WO (1) WO2015073978A2 (OSRAM)

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KR102241836B1 (ko) * 2019-06-14 2021-04-21 솔젠트 (주) 듀얼 체크 올리고를 이용한 유전자 다형성 검사 방법
CN113088569A (zh) * 2020-01-09 2021-07-09 北京中因科技有限公司 一种多重荧光定量pcr试剂盒
CN113999899A (zh) * 2020-07-28 2022-02-01 首都医科大学附属北京同仁医院 一种检测tgfbi基因突变的试剂盒
CN115820837A (zh) * 2022-11-04 2023-03-21 温州谱希基因科技有限公司 一种角膜营养不良的pcr检测试剂盒及其应用
CN118222692A (zh) * 2022-12-21 2024-06-21 北京中因医学检验实验室有限公司 一种人tgfbi基因分型检测的引物探针组合物及其应用
CN117417997B (zh) * 2023-10-26 2025-07-29 上海谱希和光基因科技有限公司 一种诊断圆锥角膜的基因组生物标志物组合
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WO2015073978A9 (en) 2016-06-23
AU2014348279A9 (en) 2016-07-28
JP2017501685A (ja) 2017-01-19
WO2015073978A2 (en) 2015-05-21
TW202346604A (zh) 2023-12-01
TWI812047B (zh) 2023-08-11
AU2014348279A1 (en) 2016-06-09
US20160319357A1 (en) 2016-11-03
EP3068908B1 (en) 2021-01-06
US20230348984A1 (en) 2023-11-02
CN105899681B (zh) 2021-06-22
AU2021202884B2 (en) 2023-04-06
KR102293785B1 (ko) 2021-08-26
JP2020039339A (ja) 2020-03-19
KR102483783B1 (ko) 2022-12-30
US11525160B2 (en) 2022-12-13
TWI755350B (zh) 2022-02-21
AU2014348279B2 (en) 2021-02-18
EP3068908A4 (en) 2017-08-23
KR20160079117A (ko) 2016-07-05
EP3068908A2 (en) 2016-09-21
CN113604551A (zh) 2021-11-05
SG10201804076RA (en) 2018-06-28
KR20210099204A (ko) 2021-08-11
CN105899681A (zh) 2016-08-24
WO2015073978A3 (en) 2015-07-16
EP3872192A1 (en) 2021-09-01
TW202223098A (zh) 2022-06-16
KR20230007558A (ko) 2023-01-12
AU2021202884A1 (en) 2021-06-03
JP7077289B2 (ja) 2022-05-30
TW201610167A (zh) 2016-03-16

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