TW332814B - Morphinan derivative - Google Patents
Morphinan derivativeInfo
- Publication number
- TW332814B TW332814B TW082100590A TW82100590A TW332814B TW 332814 B TW332814 B TW 332814B TW 082100590 A TW082100590 A TW 082100590A TW 82100590 A TW82100590 A TW 82100590A TW 332814 B TW332814 B TW 332814B
- Authority
- TW
- Taiwan
- Prior art keywords
- agents
- diuretic
- analgesic
- morphinan derivative
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Fertilizers (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1011592 | 1992-01-23 | ||
JP29430892 | 1992-11-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW332814B true TW332814B (en) | 1998-06-01 |
Family
ID=26345314
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW082100590A TW332814B (en) | 1992-01-23 | 1993-01-30 | Morphinan derivative |
Country Status (15)
Country | Link |
---|---|
US (2) | US6323212B1 (zh) |
EP (2) | EP0846694A1 (zh) |
JP (1) | JP2525552B2 (zh) |
KR (1) | KR970011390B1 (zh) |
AT (1) | ATE172201T1 (zh) |
AU (2) | AU666702B2 (zh) |
CA (1) | CA2105072C (zh) |
DE (1) | DE69321525T2 (zh) |
DK (1) | DK0577847T3 (zh) |
ES (1) | ES2121988T3 (zh) |
FI (1) | FI106126B (zh) |
NO (1) | NO302755B1 (zh) |
NZ (1) | NZ246687A (zh) |
TW (1) | TW332814B (zh) |
WO (1) | WO1993015081A1 (zh) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2121988T3 (es) | 1992-01-23 | 1998-12-16 | Toray Industries | Derivado de morfinano y uso medicinal. |
AU683664B2 (en) * | 1993-06-30 | 1997-11-20 | Toray Industries, Inc. | Antitussive |
DE69414085T2 (de) * | 1993-07-19 | 1999-03-18 | Toray Industries, Inc., Tokio/Tokyo | Wirkstoff zum schutze von gehirnzellen |
WO1995003308A1 (en) * | 1993-07-23 | 1995-02-02 | Toray Industries, Inc. | Morphinan derivative and medicinal use |
SE9401727D0 (sv) * | 1994-05-18 | 1994-05-18 | Astra Ab | New compounds I |
DE19602964A1 (de) * | 1995-12-20 | 1997-07-31 | Nycomed Arzneimittel Gmbh | Neue Morphinderivate, Verfahren zu deren Herstellung und deren Verwendung |
US6239154B1 (en) | 1996-03-08 | 2001-05-29 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
US5763445A (en) | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
EP0829481A1 (en) * | 1996-09-16 | 1998-03-18 | Pfizer Inc. | Morphinan hydroxamic acid compounds |
ES2236630T3 (es) * | 1996-11-25 | 2005-07-16 | Toray Industries, Inc. | Agente antipruritico. |
DE69838662T2 (de) | 1997-03-27 | 2008-08-28 | Toray Industries, Inc. | Morphinanderivate und ihre medizinische Anwendung |
ES2217563T3 (es) | 1997-07-11 | 2004-11-01 | Toray Industries, Inc. | Compuestos medicinales estables que contienen derivados de 4,5-epoximorfinado. |
US5760023A (en) * | 1997-07-14 | 1998-06-02 | Adolor Corporation | Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith |
NZ500438A (en) * | 1997-07-14 | 2001-11-30 | Adolor Corp | Compositions containing a compound having kappa opioid agonist activity for treatment of pruritis (itchiness) |
AU6117298A (en) * | 1997-07-25 | 1999-02-16 | Toray Industries, Inc. | Hyponatremia remedies |
CA2270955C (en) * | 1997-09-02 | 2007-08-07 | Toray Industries Inc. | Pharmaceutical composition containing morphinan derivative for treating drug dependence |
US6083944A (en) * | 1997-10-07 | 2000-07-04 | Cephalon, Inc. | Quinoline-containing α-ketoamide cysteine and serine protease inhibitors |
TW570920B (en) * | 1998-12-22 | 2004-01-11 | Janssen Pharmaceutica Nv | 4-(aminomethyl)-piperidine benzamides for treating gastrointestinal disorders |
CN1204139C (zh) * | 1999-08-24 | 2005-06-01 | 东丽株式会社 | 神经性疼痛治疗剂 |
US6688746B2 (en) * | 1999-12-03 | 2004-02-10 | Iouri Malov | Field testing using spread spectrum technique |
WO2001074819A1 (fr) * | 2000-04-03 | 2001-10-11 | Toray Industries, Inc. | Agents analgesiques contenant des derives de n-oxyde de morphinane en tant que principe actif |
CN100398154C (zh) | 2001-03-30 | 2008-07-02 | 东丽株式会社 | 精神神经疾病治疗药 |
WO2002080918A1 (fr) * | 2001-04-02 | 2002-10-17 | Toray Industries, Inc. | Agent therapeutique ou prophylactique en cas de miction frequente ou d'incontinence urinaire |
DE10161963A1 (de) * | 2001-12-17 | 2003-07-03 | Johannes Schuetz | 6-Aminomorphinanderivate, Herstellungsverfahren dafür und deren Verwendung |
EP1506174B1 (en) | 2002-05-17 | 2015-09-30 | Taiwanj Pharmaceuticals Co., Ltd. | Use of naltrexone for treating kidney and liver damage |
US7501433B2 (en) * | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
JP4016986B2 (ja) | 2002-10-09 | 2007-12-05 | 東レ株式会社 | 頻尿もしくは尿失禁の治療または予防剤および含窒素環状置換基を有するモルヒナン誘導体 |
US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
CA2527693C (en) * | 2003-06-04 | 2018-09-18 | Harry G. Brittain | Polymorphic forms of naltrexone |
DK1758452T3 (en) * | 2004-05-28 | 2017-05-01 | Human Biomolecular Res Inst | METABOLIC STABLE ANALGETICS AND Painkillers |
TW200621785A (en) * | 2004-11-04 | 2006-07-01 | Toray Industries | Analgesic |
NZ563133A (en) * | 2005-04-06 | 2010-07-30 | Toray Industries | Crystals of morphinan derivative and process for producing the same |
ES2307352B1 (es) * | 2005-04-12 | 2009-09-18 | Bti, I+D, S.L. | Implante dental y piezas destinadas a ser conectadas a un implante dental, y la conexion interna entre el implante dental y cada pieza. |
EP2010539B1 (en) * | 2006-04-21 | 2017-06-14 | Nektar Therapeutics | Stereoselective reduction of a morphinone |
EP2151240B1 (en) | 2007-04-24 | 2013-06-12 | Toray Industries, Inc. | Therapeutic or prophylactic agent for dyskinesia |
CN101686976B (zh) | 2007-04-26 | 2013-04-24 | 东丽株式会社 | 含有4,5-环氧基吗啡喃衍生物的稳定的固体制剂 |
CN101778632B (zh) | 2007-06-22 | 2012-02-29 | 东丽株式会社 | 综合失调症的治疗或预防药 |
BRPI0817804A8 (pt) | 2007-10-05 | 2017-04-18 | Toray Industries | Agente terapêutico para melhorar as propriedades da pele compreendendo um derivado de morfinano ou qualquer um de seus sais de adição de ácido farmacologicamente permissíveis como um ingrediente ativo |
ES2671897T3 (es) * | 2008-02-14 | 2018-06-11 | Alkermes, Inc. | Compuestos opioides selectivos |
WO2010006299A1 (en) * | 2008-07-11 | 2010-01-14 | Regents Of The University Of Minnesota | Analgesic agents |
JP5648480B2 (ja) | 2008-10-24 | 2015-01-07 | 東レ株式会社 | 4,5−エポキシモルヒナン誘導体を含有する安定な錠剤 |
EP2398805A1 (en) * | 2009-02-23 | 2011-12-28 | Mallinckrodt LLC | (+)-morphinanium quaternary salts and processes for their production |
US8946419B2 (en) | 2009-02-23 | 2015-02-03 | Mallinckrodt Llc | (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives |
US8563727B2 (en) * | 2009-02-23 | 2013-10-22 | Mallinckrodt Llc | (+)-morphinanium N-oxides and processes for their production |
WO2010096791A1 (en) * | 2009-02-23 | 2010-08-26 | Mallinckrodt Inc. | (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives |
WO2010144641A1 (en) * | 2009-06-11 | 2010-12-16 | Mallinckrodt Inc. | Preparation of 6-alpha-amino n-substituted morphinans by catalytic hydrogen transfer |
EP2440561B1 (en) * | 2009-06-11 | 2014-04-30 | Mallinckrodt LLC | Reductive amination of 6-keto normorphinans by catalytic hydrogen transfer |
WO2011009020A2 (en) | 2009-07-16 | 2011-01-20 | Mallinckrodt Inc. | Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers |
US10363251B2 (en) | 2009-07-16 | 2019-07-30 | Mallinckrodt Llc | (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof |
MX362830B (es) | 2010-01-29 | 2019-02-14 | Toray Industries | Agente terapeutico o profilactico para enfermedades del tracto biliar. |
ES2645725T3 (es) | 2010-06-11 | 2017-12-07 | Rhodes Technologies | Procesos catalizados por metales de transición para la preparación de compuestos de N-alilo y uso de los mismos |
EP2580218B1 (en) | 2010-06-11 | 2015-02-25 | Rhodes Technologies | Process for n-dealkylation of tertiary amines |
CA2768199C (en) | 2010-07-16 | 2018-08-28 | Mallinckrodt Llc | (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof |
JP6013345B2 (ja) * | 2010-10-19 | 2016-10-25 | メモリアル スローン−ケタリング キャンサー センター | 痛み治療用の4,5a−エポキシモルフィナンの6−アミド誘導体 |
CN103327977B (zh) | 2011-01-31 | 2016-05-04 | 东丽株式会社 | 恶液质的治疗或预防剂 |
MX2013013634A (es) | 2011-06-09 | 2013-12-12 | Mallinckrodt Llc | Aminacion reductiva de 6-ceto-morfinanos por transfrencia catalitica de hidrogeno. |
ES2566620T3 (es) | 2011-09-08 | 2016-04-14 | Mallinckrodt Llc | Procesamiento de alcaloides sin el aislamiento de intermedios |
DK2884978T3 (da) | 2012-08-16 | 2019-09-30 | Scripps Research Inst | Nye Kappa-opioidligander |
TWI449704B (zh) * | 2013-04-26 | 2014-08-21 | Everlight Chem Ind Corp | 嗎啡喃衍生物之結晶、其製造方法、及使用其之醫藥組成物 |
WO2015082932A1 (en) | 2013-12-05 | 2015-06-11 | The University Of Bath | Novel opioid compounds and their uses |
JP2015166331A (ja) * | 2014-05-14 | 2015-09-24 | 遼東化学工業株式会社 | ナルフラフィンの結晶およびその製造方法 |
WO2016152953A1 (ja) * | 2015-03-24 | 2016-09-29 | 東レ株式会社 | モルヒナン誘導体及びその医薬用途 |
EP4212532A3 (en) | 2015-04-30 | 2023-09-27 | Memorial Sloan Kettering Cancer Center | Mitragynine analogs and uses thereof |
AU2016346558A1 (en) | 2015-10-29 | 2018-04-26 | University Of Tsukuba | Morphinan derivative and medical usage thereof |
JP2019509321A (ja) | 2016-03-22 | 2019-04-04 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 疼痛を処置するための組み合わせ |
EP3458061B1 (en) * | 2016-05-19 | 2023-01-18 | Virginia Commonwealth University | Potent and selective mu opioid receptor modulators |
JP6814470B2 (ja) | 2017-02-10 | 2021-01-20 | 国立大学法人 筑波大学 | モルヒナン誘導体 |
WO2019168985A1 (en) * | 2018-02-27 | 2019-09-06 | Delpor, Inc. | Compositions for small molecule therapeutic agent compounds |
EP3761982B1 (en) | 2018-03-08 | 2024-10-09 | Victoria Link Ltd | Use of nalfurafine for the treatment of demyelinating diseases |
US11214577B2 (en) * | 2019-03-29 | 2022-01-04 | Humanwell Pharmaceutical US | Morphinans useful for treating medical disorders |
CA3146163A1 (en) * | 2019-07-08 | 2021-01-14 | University Of Health Sciences & Pharmacy In St. Louis | G-protein biased opioid receptor agonist/analgesics with reduced arrestin recruitment |
KR20220071223A (ko) | 2019-09-30 | 2022-05-31 | 닛뽕 케미파 가부시키가이샤 | 아제판 유도체 |
EP4049658A4 (en) | 2019-10-24 | 2023-11-22 | Toray Industries, Inc. | THERAPEUTIC OR PROPHYLACTIC AGENT AGAINST CACHEXIA |
TW202216145A (zh) | 2020-06-30 | 2022-05-01 | 日商東麗股份有限公司 | 伴隨代謝異常之疾病或症候群中的肌力低下症狀之改善劑或預防劑 |
CN115181109B (zh) * | 2021-04-02 | 2024-06-04 | 南京正大天晴制药有限公司 | 吗啡喃衍生物的晶体及其制备方法 |
AU2022260191A1 (en) | 2021-04-23 | 2023-10-26 | Toray Industries, Inc. | Therapeutic or prophylactic agent for cachexia accompanied by ghrelin resistance |
IL309232A (en) | 2021-06-14 | 2024-02-01 | Scorpion Therapeutics Inc | History of urea which can be used to treat cancer |
WO2023190665A1 (ja) * | 2022-03-29 | 2023-10-05 | 東レ株式会社 | モルヒナン誘導体及びその医薬用途 |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL290054A (zh) * | ||||
US3236851A (en) * | 1966-02-22 | Unsaturated morphinan derivatives | ||
DE622231C (de) * | 1934-03-09 | 1935-11-23 | Hermann Fischer Dr | Verfahren zur Herstellung von Diacetylmorphin |
GB864107A (en) | 1958-09-10 | 1961-03-29 | Albert Boehringer | Morphine derivatives |
GB919311A (en) * | 1958-10-29 | 1963-02-20 | T & H Smith Ltd | Derivatives of 14-hydroxycodeine and their preparation |
DE2254298A1 (de) * | 1972-11-06 | 1974-05-16 | Boehringer Sohn Ingelheim | Neue (heteroarylmethyl)-normorphine, deren saeureadditionssalze, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
GB1587831A (en) * | 1977-03-23 | 1981-04-08 | Reckitt & Colmann Prod Ltd | Morphine derivatives |
GB1593191A (en) | 1977-03-23 | 1981-07-15 | Reckitt & Colmann Prod Ltd | Derivatives of morphine |
US4362870A (en) * | 1980-01-16 | 1982-12-07 | Regents Of The University Of Minnesota | Selective opioid receptor alkylating agents |
JPS574991A (en) | 1980-06-10 | 1982-01-11 | Sankyo Co Ltd | Cyclopropylmethylnormorphine-6-sulfuric ester |
US4401672A (en) | 1981-10-13 | 1983-08-30 | Regents Of The University Of Minnesota | Non-addictive narcotic antitussive preparation |
US4668685A (en) * | 1984-07-05 | 1987-05-26 | E.I. Du Pont De Nemours And Company | Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans, which are analgesics or narcotic antagonists |
US4767718A (en) * | 1984-06-18 | 1988-08-30 | Southern Illinois University Foundation | Fluorescent opioid reagents and methods of use thereof in the detection of opioid receptors |
IN163125B (zh) | 1985-01-08 | 1988-08-13 | Alkaloida Vegyeszeti Gyar | |
HU196376B (en) * | 1985-05-23 | 1988-11-28 | Sandoz Ag | Process for preparing morphinane derivatives and pharmaceutical compositions containing such compounds |
DE3617182A1 (de) | 1985-05-23 | 1986-11-27 | Sandoz-Patent-GmbH, 79539 Lörrach | Morphinan-derivate |
US4730048A (en) | 1985-12-12 | 1988-03-08 | Regents Of The University Of Minnesota | Gut-selective opiates |
US4806556A (en) | 1985-12-12 | 1989-02-21 | Regents Of The University Of Minnesota | Gut-selective opiates |
US4673679A (en) * | 1986-05-14 | 1987-06-16 | E. I. Du Pont De Nemours And Company | Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration |
US4816586A (en) * | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
JPH01149788A (ja) | 1987-12-08 | 1989-06-12 | Chugai Pharmaceut Co Ltd | 新規なモルヒネ誘導体 |
FR2636330B1 (fr) | 1988-09-13 | 1990-11-30 | Sanofi Sa | Procede de preparation de derives de morphinane |
US5219861A (en) * | 1988-12-21 | 1993-06-15 | Chugai Seiyaku Kabushiki Kaisha | 6 β-Thiomorphine derivatives |
KR900009650A (ko) * | 1988-12-21 | 1990-07-05 | 사노하지메 | 신규 모르핀 유도체 |
US5258386A (en) * | 1991-06-05 | 1993-11-02 | The United States Of America As Represented By The Secretary Of The Army | (+)-3-substituted-N alkylmorphinans, synthesis and use as anticonvulsant and neuroprotective agents |
ES2121988T3 (es) * | 1992-01-23 | 1998-12-16 | Toray Industries | Derivado de morfinano y uso medicinal. |
AU683664B2 (en) * | 1993-06-30 | 1997-11-20 | Toray Industries, Inc. | Antitussive |
-
1993
- 1993-01-22 ES ES93902520T patent/ES2121988T3/es not_active Expired - Lifetime
- 1993-01-22 DE DE69321525T patent/DE69321525T2/de not_active Expired - Lifetime
- 1993-01-22 JP JP5509616A patent/JP2525552B2/ja not_active Expired - Lifetime
- 1993-01-22 AU AU33671/93A patent/AU666702B2/en not_active Expired
- 1993-01-22 NZ NZ246687A patent/NZ246687A/en not_active IP Right Cessation
- 1993-01-22 KR KR1019930702860A patent/KR970011390B1/ko not_active IP Right Cessation
- 1993-01-22 AT AT93902520T patent/ATE172201T1/de active
- 1993-01-22 EP EP98100805A patent/EP0846694A1/en not_active Withdrawn
- 1993-01-22 US US08/108,643 patent/US6323212B1/en not_active Expired - Lifetime
- 1993-01-22 DK DK93902520T patent/DK0577847T3/da active
- 1993-01-22 WO PCT/JP1993/000080 patent/WO1993015081A1/ja active IP Right Grant
- 1993-01-22 CA CA002105072A patent/CA2105072C/en not_active Expired - Lifetime
- 1993-01-22 EP EP93902520A patent/EP0577847B1/en not_active Expired - Lifetime
- 1993-01-30 TW TW082100590A patent/TW332814B/zh not_active IP Right Cessation
- 1993-09-22 NO NO933376A patent/NO302755B1/no not_active IP Right Cessation
- 1993-09-22 FI FI934144A patent/FI106126B/fi not_active IP Right Cessation
-
1995
- 1995-12-22 AU AU40671/95A patent/AU686483B2/en not_active Expired
-
2000
- 2000-03-31 US US09/541,793 patent/US6277859B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK0577847T3 (da) | 1999-06-23 |
ATE172201T1 (de) | 1998-10-15 |
FI106126B (fi) | 2000-11-30 |
DE69321525T2 (de) | 1999-03-04 |
NZ246687A (en) | 1996-12-20 |
US6277859B1 (en) | 2001-08-21 |
US6323212B1 (en) | 2001-11-27 |
EP0577847A1 (en) | 1994-01-12 |
KR970011390B1 (ko) | 1997-07-10 |
AU4067195A (en) | 1996-03-07 |
EP0577847B1 (en) | 1998-10-14 |
CA2105072A1 (en) | 1993-07-24 |
FI934144A0 (fi) | 1993-09-22 |
ES2121988T3 (es) | 1998-12-16 |
WO1993015081A1 (fr) | 1993-08-05 |
NO933376D0 (no) | 1993-09-22 |
NO933376L (no) | 1993-09-23 |
JP2525552B2 (ja) | 1996-08-21 |
EP0577847A4 (en) | 1994-12-07 |
AU686483B2 (en) | 1998-02-05 |
AU666702B2 (en) | 1996-02-22 |
AU3367193A (en) | 1993-09-01 |
CA2105072C (en) | 1998-07-28 |
FI934144A (fi) | 1993-09-22 |
DE69321525D1 (de) | 1998-11-19 |
JPH08502275A (ja) | 1996-03-12 |
EP0846694A1 (en) | 1998-06-10 |
NO302755B1 (no) | 1998-04-20 |
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