NO964871L - Nye agonistforbindelser - Google Patents

Nye agonistforbindelser

Info

Publication number
NO964871L
NO964871L NO964871A NO964871A NO964871L NO 964871 L NO964871 L NO 964871L NO 964871 A NO964871 A NO 964871A NO 964871 A NO964871 A NO 964871A NO 964871 L NO964871 L NO 964871L
Authority
NO
Norway
Prior art keywords
agonist compounds
new agonist
new
compounds
therapy
Prior art date
Application number
NO964871A
Other languages
English (en)
Other versions
NO964871D0 (no
Inventor
Helmut Schmidhammer
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO964871L publication Critical patent/NO964871L/no
Publication of NO964871D0 publication Critical patent/NO964871D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Nye morfinanderivater av formel (I). deres farmasøytisk akseptable salter, en fremgangsmåte for deres fremstilling og deres anvendelse i terapi.i
NO964871A 1994-05-18 1996-11-15 Nye agonistforbindelser NO964871D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9401727A SE9401727D0 (sv) 1994-05-18 1994-05-18 New compounds I
PCT/SE1995/000504 WO1995031464A1 (en) 1994-05-18 1995-05-09 New agonist compounds

Publications (2)

Publication Number Publication Date
NO964871L true NO964871L (no) 1996-11-15
NO964871D0 NO964871D0 (no) 1996-11-15

Family

ID=20394058

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964871A NO964871D0 (no) 1994-05-18 1996-11-15 Nye agonistforbindelser

Country Status (18)

Country Link
US (1) US5886001A (no)
EP (1) EP0759923A1 (no)
JP (1) JPH10500132A (no)
CN (1) CN1152314A (no)
AU (1) AU690281B2 (no)
BR (1) BR9507656A (no)
CA (1) CA2189139A1 (no)
FI (1) FI964576A0 (no)
HU (1) HU9603171D0 (no)
IL (1) IL113627A0 (no)
IS (1) IS4381A (no)
NO (1) NO964871D0 (no)
NZ (1) NZ287177A (no)
PL (1) PL317250A1 (no)
SE (1) SE9401727D0 (no)
SK (1) SK139696A3 (no)
WO (1) WO1995031464A1 (no)
ZA (1) ZA953699B (no)

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AU712012B2 (en) * 1995-09-26 1999-10-28 Toray Industries, Inc. Indole derivatives and medical application thereof
CN1117754C (zh) * 1997-01-16 2003-08-13 东丽株式会社 吲哚并吗啡喃衍生物及其组合物
GB9717629D0 (en) * 1997-08-21 1997-10-22 Johnson Matthey Plc Removal of residual organic solvents
WO2000008027A1 (en) * 1998-08-06 2000-02-17 Regents Of The University Of Minnesota Kappa (op2) opioid receptor antagonists
WO2002080919A1 (en) * 2001-04-06 2002-10-17 Regents Of The University Of Minnesota Therapeutic compounds and methods
US7232829B2 (en) 2001-04-06 2007-06-19 Regents Of The University Of Minnesota Therapeutic compounds and methods
DE10229842A1 (de) * 2002-07-03 2004-02-05 Helmut Prof. Dr. Schmidhammer Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung
NZ546834A (en) 2003-10-01 2010-03-26 Adolor Corp Spirocyclic heterocyclic derivatives and methods of their use
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
EP2399577A1 (en) 2006-09-12 2011-12-28 Adolor Corporation Use of N-containing spirocompounds for the enhancement of cognitive function
US9321116B2 (en) * 2009-03-05 2016-04-26 United Technologies Corporation Cold metal transfer gas metal arc welding apparatus and method of operation
EP2340832A1 (en) 2009-12-23 2011-07-06 Universität Innsbruck Morphinan-6-one compounds for the treatment or prevention of neurodegenerative diseases
JP6091426B2 (ja) * 2010-12-23 2017-03-08 フェニックス ファーマラブス インク 鎮痛剤として有用な新規モルフィナン類
WO2014037832A2 (en) 2012-09-06 2014-03-13 Mahesh Kandula Compositions and methods for the treatment of epilepsy and neurological diseases
US9399634B2 (en) 2012-05-07 2016-07-26 Cellix Bio Private Limited Compositions and methods for the treatment of depression
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US9273061B2 (en) 2012-05-10 2016-03-01 Cellix Bio Private Limited Compositions and methods for the treatment of chronic pain
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JP2015518854A (ja) 2012-05-23 2015-07-06 セリックスビオ プライヴェート リミテッド 多発性硬化症の治療のための組成物および方法
WO2013175344A2 (en) 2012-05-23 2013-11-28 Mahesh Kandula Compositions and methods for the treatment of periodontitis and rheumatoid arthritis
US9765020B2 (en) 2012-05-23 2017-09-19 Cellix Bio Private Limited Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis
WO2013175376A2 (en) 2012-05-23 2013-11-28 Mahesh Kandula Compositions and methods for the treatment of local pain
CN104603100A (zh) 2012-05-23 2015-05-06 塞利克斯比奥私人有限公司 用于治疗炎症性肠病的组合物和方法
US9108942B1 (en) 2014-11-05 2015-08-18 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
WO2014020480A2 (en) 2012-08-03 2014-02-06 Mahesh Kandula Compositions and methods for the treatment migraine and neurologic diseases
US9624168B2 (en) 2012-09-06 2017-04-18 Cellix Bio Private Limited Compositions and methods for the treatment inflammation and lipid disorders
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HU231191B1 (hu) 2013-04-15 2021-08-30 Szegedi Tudományegyetem Izotóp tartalmú morfin molekulák
US9333187B1 (en) 2013-05-15 2016-05-10 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
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US9969746B2 (en) 2013-12-05 2018-05-15 The University Of Bath Opioid compounds and their uses
US9096537B1 (en) 2014-12-31 2015-08-04 Mahesh Kandula Compositions and methods for the treatment of mucositis
WO2016046835A1 (en) 2014-09-26 2016-03-31 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological disorders
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EP3212626B1 (en) 2014-10-27 2018-11-07 Cellix Bio Private Limited Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis
US9290486B1 (en) 2014-11-05 2016-03-22 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy
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US9321716B1 (en) 2014-11-05 2016-04-26 Cellix Bio Private Limited Compositions and methods for the treatment of metabolic syndrome
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US9175008B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Prodrugs of anti-platelet agents
US10034871B2 (en) 2014-11-07 2018-07-31 Regents Of The University Of Minnesota Salts and compositions useful for treating disease
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en) 2014-12-17 2015-12-08 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
SG11201705524SA (en) 2015-01-06 2017-08-30 Cellix Bio Private Ltd Compositions and methods for the treatment of inflammation and pain
JP2019509321A (ja) 2016-03-22 2019-04-04 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 疼痛を処置するための組み合わせ

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
JP2906654B2 (ja) * 1989-11-28 1999-06-21 東レ株式会社 免疫抑制剤及びその製造方法
US5223507A (en) * 1992-01-21 1993-06-29 G. D. Searle & Co. Method of using opioid compounds as delta opioid selective agonist analgesics
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
ES2121988T3 (es) * 1992-01-23 1998-12-16 Toray Industries Derivado de morfinano y uso medicinal.
WO1994007896A1 (en) * 1992-09-29 1994-04-14 Toray Industries, Inc. Indole derivative, process for producing the same, and medicinal use thereof
US5464841A (en) * 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
US5780479A (en) * 1997-04-04 1998-07-14 Regents Of The University Of Minnesota Use of opioid antagonists to treat impulse-control disorders

Also Published As

Publication number Publication date
EP0759923A1 (en) 1997-03-05
CN1152314A (zh) 1997-06-18
IS4381A (is) 1996-11-08
BR9507656A (pt) 1997-09-23
JPH10500132A (ja) 1998-01-06
AU690281B2 (en) 1998-04-23
SE9401727D0 (sv) 1994-05-18
ZA953699B (en) 1995-11-20
PL317250A1 (en) 1997-04-01
SK139696A3 (en) 1997-05-07
FI964576A (fi) 1996-11-15
US5886001A (en) 1999-03-23
WO1995031464A1 (en) 1995-11-23
HU9603171D0 (en) 1997-01-28
CA2189139A1 (en) 1995-11-23
NO964871D0 (no) 1996-11-15
FI964576A0 (fi) 1996-11-15
AU2581895A (en) 1995-12-05
IL113627A0 (en) 1995-08-31
NZ287177A (en) 1997-11-24

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