SE9401728D0 - New compounds II - Google Patents
New compounds IIInfo
- Publication number
- SE9401728D0 SE9401728D0 SE9401728A SE9401728A SE9401728D0 SE 9401728 D0 SE9401728 D0 SE 9401728D0 SE 9401728 A SE9401728 A SE 9401728A SE 9401728 A SE9401728 A SE 9401728A SE 9401728 D0 SE9401728 D0 SE 9401728D0
- Authority
- SE
- Sweden
- Prior art keywords
- pct
- new compounds
- sec
- date
- pub
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9401728A SE9401728D0 (sv) | 1994-05-18 | 1994-05-18 | New compounds II |
IL11363195A IL113631A0 (en) | 1994-05-18 | 1995-05-07 | New antagonist compounds |
ZA953701A ZA953701B (en) | 1994-05-18 | 1995-05-08 | New atagonist compounds |
AT95920328T ATE259815T1 (de) | 1994-05-18 | 1995-05-09 | Neue antagonistische verbindungen |
US08/507,369 US6136817A (en) | 1994-05-18 | 1995-05-09 | Opioid receptor antagonist compounds |
JP52955395A JP4117801B2 (ja) | 1994-05-18 | 1995-05-09 | 新規な拮抗剤化合物 |
DE69532580T DE69532580T2 (de) | 1994-05-18 | 1995-05-09 | Neue antagonistische verbindungen |
ES95920328T ES2214501T3 (es) | 1994-05-18 | 1995-05-09 | Nuevos compuestos antagonistas. |
CA002189140A CA2189140C (en) | 1994-05-18 | 1995-05-09 | New antagonist compounds |
PCT/SE1995/000503 WO1995031463A1 (en) | 1994-05-18 | 1995-05-09 | New antagonist compounds |
AU25817/95A AU690996B2 (en) | 1994-05-18 | 1995-05-09 | New antagonist compounds |
EP95920328A EP0759922B1 (en) | 1994-05-18 | 1995-05-09 | New antagonist compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9401728A SE9401728D0 (sv) | 1994-05-18 | 1994-05-18 | New compounds II |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9401728D0 true SE9401728D0 (sv) | 1994-05-18 |
Family
ID=20394059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9401728A SE9401728D0 (sv) | 1994-05-18 | 1994-05-18 | New compounds II |
Country Status (11)
Country | Link |
---|---|
US (1) | US6136817A (sv) |
EP (1) | EP0759922B1 (sv) |
JP (1) | JP4117801B2 (sv) |
AT (1) | ATE259815T1 (sv) |
AU (1) | AU690996B2 (sv) |
DE (1) | DE69532580T2 (sv) |
ES (1) | ES2214501T3 (sv) |
IL (1) | IL113631A0 (sv) |
SE (1) | SE9401728D0 (sv) |
WO (1) | WO1995031463A1 (sv) |
ZA (1) | ZA953701B (sv) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0805157B1 (en) * | 1995-09-26 | 2003-06-04 | Toray Industries, Inc. | Indole derivatives and medicinal use thereof |
US5994327A (en) * | 1995-11-17 | 1999-11-30 | Astra Ab | Process for the preparation of morphinans |
EP0946564A1 (en) * | 1996-11-19 | 1999-10-06 | Astra Aktiebolag | New process for the preparation of morphinans |
JP4110579B2 (ja) * | 1997-01-16 | 2008-07-02 | 東レ株式会社 | インドロモルヒナン誘導体および脳障害治療・予防剤 |
DE19939044A1 (de) * | 1999-08-18 | 2001-03-15 | Gruenenthal Gmbh | Verwendung von Morphinanderivaten als Arzneimittel |
WO2003070175A2 (en) * | 2002-02-15 | 2003-08-28 | Howard Brooks-Korn | Use of opioid compound to treat a neurologic or neurogenic disorder |
DE10229842A1 (de) * | 2002-07-03 | 2004-02-05 | Helmut Prof. Dr. Schmidhammer | Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung |
ATE444295T1 (de) | 2002-11-08 | 2009-10-15 | Mallinckrodt Inc | Verfahren zur herstellung von quaternäre n-alkyl morphinan alkaloid salzen |
EP1595541A1 (en) * | 2004-05-12 | 2005-11-16 | Alcasynn Pharmaceuticals Gmbh | Use of opioid receptor antagonist compounds for the prevention and/or treatment of diseases associated with the target calcineurin |
WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
JPWO2006064779A1 (ja) * | 2004-12-14 | 2008-06-12 | 塩野義製薬株式会社 | 6’位にカルボキシを有するインドロモルヒナン誘導体 |
WO2007123920A2 (en) * | 2006-04-18 | 2007-11-01 | Joseph Nicholas Logan | Spinal rod system |
MX2009002844A (es) * | 2006-09-20 | 2009-03-30 | Mallinckrodt Inc | Preparacion de morfinan-6-onas sustituidas y sales e intermediarios de las mismas. |
WO2008109156A2 (en) * | 2007-03-06 | 2008-09-12 | Mallinckrodt Inc. | Process for the preparation of quaternary n-alkyl morphinan alkaloid salts |
US9040726B2 (en) | 2007-03-06 | 2015-05-26 | Mallinckrodt Llc | Process for the preparation of quaternary N-alkyl morphinan alkaloid salts |
US8883817B2 (en) * | 2007-10-18 | 2014-11-11 | Aiko Biotechnology | Combination analgesic employing opioid and neutral antagonist |
US8748448B2 (en) | 2007-10-18 | 2014-06-10 | Aiko Biotechnology | Combination analgesic employing opioid agonist and neutral antagonist |
NZ586194A (en) | 2007-12-17 | 2012-07-27 | Mallinckrodt Llc | Processes for the production of (+)-'nal' morphinan compounds |
WO2009132313A2 (en) * | 2008-04-25 | 2009-10-29 | Progenics Pharmaceuticals, Inc. | Morphinan derivatives of organic and inorganic acids |
US8148528B2 (en) * | 2008-05-27 | 2012-04-03 | Mallinckrodt Llc | Processes and compounds for the preparation of normorphinans |
WO2010028004A2 (en) | 2008-09-03 | 2010-03-11 | Mallinckrodt Inc. | Substituted berbines and processes for their synthesis |
EP2340832A1 (en) | 2009-12-23 | 2011-07-06 | Universität Innsbruck | Morphinan-6-one compounds for the treatment or prevention of neurodegenerative diseases |
JP6173431B2 (ja) * | 2013-03-08 | 2017-08-02 | 学校法人北里研究所 | モルヒナン誘導体 |
WO2015082932A1 (en) | 2013-12-05 | 2015-06-11 | The University Of Bath | Novel opioid compounds and their uses |
WO2020012245A1 (en) | 2018-07-13 | 2020-01-16 | Alkermes Pharma Ireland Limited | Thienothiophene-naltrexone prodrugs for long-acting injectable compositions |
US10799496B2 (en) | 2018-07-13 | 2020-10-13 | Alkermes Pharma Ireland Limited | Naphthylenyl compounds for long-acting injectable compositions and related methods |
WO2020094634A1 (en) | 2018-11-05 | 2020-05-14 | Alkermes Pharma Ireland Limited | Thiophene prodrugs of naltroxene for long-acting injectable compositions and related methods |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816586A (en) * | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
JP2906654B2 (ja) * | 1989-11-28 | 1999-06-21 | 東レ株式会社 | 免疫抑制剤及びその製造方法 |
JPH04342529A (ja) * | 1991-05-21 | 1992-11-30 | Toray Ind Inc | 抗アレルギー剤 |
US5223507A (en) * | 1992-01-21 | 1993-06-29 | G. D. Searle & Co. | Method of using opioid compounds as delta opioid selective agonist analgesics |
US5225417A (en) * | 1992-01-21 | 1993-07-06 | G. D. Searle & Co. | Opioid agonist compounds |
DE69332945T2 (de) * | 1992-09-29 | 2004-05-19 | Toray Industries, Inc. | Indol-derivat, verfahren zu dessen herstellung und dessen medizinische anwendung |
-
1994
- 1994-05-18 SE SE9401728A patent/SE9401728D0/sv unknown
-
1995
- 1995-05-07 IL IL11363195A patent/IL113631A0/xx unknown
- 1995-05-08 ZA ZA953701A patent/ZA953701B/xx unknown
- 1995-05-09 DE DE69532580T patent/DE69532580T2/de not_active Expired - Lifetime
- 1995-05-09 AU AU25817/95A patent/AU690996B2/en not_active Ceased
- 1995-05-09 AT AT95920328T patent/ATE259815T1/de not_active IP Right Cessation
- 1995-05-09 WO PCT/SE1995/000503 patent/WO1995031463A1/en active IP Right Grant
- 1995-05-09 JP JP52955395A patent/JP4117801B2/ja not_active Expired - Fee Related
- 1995-05-09 ES ES95920328T patent/ES2214501T3/es not_active Expired - Lifetime
- 1995-05-09 US US08/507,369 patent/US6136817A/en not_active Expired - Fee Related
- 1995-05-09 EP EP95920328A patent/EP0759922B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU690996B2 (en) | 1998-05-07 |
JP4117801B2 (ja) | 2008-07-16 |
ATE259815T1 (de) | 2004-03-15 |
ZA953701B (en) | 1995-11-20 |
DE69532580T2 (de) | 2004-07-29 |
EP0759922A1 (en) | 1997-03-05 |
JPH10500131A (ja) | 1998-01-06 |
WO1995031463A1 (en) | 1995-11-23 |
ES2214501T3 (es) | 2004-09-16 |
EP0759922B1 (en) | 2004-02-18 |
DE69532580D1 (de) | 2004-03-25 |
AU2581795A (en) | 1995-12-05 |
US6136817A (en) | 2000-10-24 |
IL113631A0 (en) | 1995-08-31 |
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