SE9401728D0 - New compounds II - Google Patents

New compounds II

Info

Publication number
SE9401728D0
SE9401728D0 SE9401728A SE9401728A SE9401728D0 SE 9401728 D0 SE9401728 D0 SE 9401728D0 SE 9401728 A SE9401728 A SE 9401728A SE 9401728 A SE9401728 A SE 9401728A SE 9401728 D0 SE9401728 D0 SE 9401728D0
Authority
SE
Sweden
Prior art keywords
pct
new compounds
sec
date
pub
Prior art date
Application number
SE9401728A
Other languages
English (en)
Inventor
Helmut Schmidhammer
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9401728A priority Critical patent/SE9401728D0/sv
Publication of SE9401728D0 publication Critical patent/SE9401728D0/sv
Priority to IL11363195A priority patent/IL113631A0/xx
Priority to ZA953701A priority patent/ZA953701B/xx
Priority to JP52955395A priority patent/JP4117801B2/ja
Priority to US08/507,369 priority patent/US6136817A/en
Priority to DE69532580T priority patent/DE69532580T2/de
Priority to ES95920328T priority patent/ES2214501T3/es
Priority to CA002189140A priority patent/CA2189140C/en
Priority to PCT/SE1995/000503 priority patent/WO1995031463A1/en
Priority to AU25817/95A priority patent/AU690996B2/en
Priority to EP95920328A priority patent/EP0759922B1/en
Priority to AT95920328T priority patent/ATE259815T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE9401728A 1994-05-18 1994-05-18 New compounds II SE9401728D0 (sv)

Priority Applications (12)

Application Number Priority Date Filing Date Title
SE9401728A SE9401728D0 (sv) 1994-05-18 1994-05-18 New compounds II
IL11363195A IL113631A0 (en) 1994-05-18 1995-05-07 New antagonist compounds
ZA953701A ZA953701B (en) 1994-05-18 1995-05-08 New atagonist compounds
AT95920328T ATE259815T1 (de) 1994-05-18 1995-05-09 Neue antagonistische verbindungen
US08/507,369 US6136817A (en) 1994-05-18 1995-05-09 Opioid receptor antagonist compounds
JP52955395A JP4117801B2 (ja) 1994-05-18 1995-05-09 新規な拮抗剤化合物
DE69532580T DE69532580T2 (de) 1994-05-18 1995-05-09 Neue antagonistische verbindungen
ES95920328T ES2214501T3 (es) 1994-05-18 1995-05-09 Nuevos compuestos antagonistas.
CA002189140A CA2189140C (en) 1994-05-18 1995-05-09 New antagonist compounds
PCT/SE1995/000503 WO1995031463A1 (en) 1994-05-18 1995-05-09 New antagonist compounds
AU25817/95A AU690996B2 (en) 1994-05-18 1995-05-09 New antagonist compounds
EP95920328A EP0759922B1 (en) 1994-05-18 1995-05-09 New antagonist compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9401728A SE9401728D0 (sv) 1994-05-18 1994-05-18 New compounds II

Publications (1)

Publication Number Publication Date
SE9401728D0 true SE9401728D0 (sv) 1994-05-18

Family

ID=20394059

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9401728A SE9401728D0 (sv) 1994-05-18 1994-05-18 New compounds II

Country Status (11)

Country Link
US (1) US6136817A (sv)
EP (1) EP0759922B1 (sv)
JP (1) JP4117801B2 (sv)
AT (1) ATE259815T1 (sv)
AU (1) AU690996B2 (sv)
DE (1) DE69532580T2 (sv)
ES (1) ES2214501T3 (sv)
IL (1) IL113631A0 (sv)
SE (1) SE9401728D0 (sv)
WO (1) WO1995031463A1 (sv)
ZA (1) ZA953701B (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0805157B1 (en) * 1995-09-26 2003-06-04 Toray Industries, Inc. Indole derivatives and medicinal use thereof
US5994327A (en) * 1995-11-17 1999-11-30 Astra Ab Process for the preparation of morphinans
EP0946564A1 (en) * 1996-11-19 1999-10-06 Astra Aktiebolag New process for the preparation of morphinans
JP4110579B2 (ja) * 1997-01-16 2008-07-02 東レ株式会社 インドロモルヒナン誘導体および脳障害治療・予防剤
DE19939044A1 (de) * 1999-08-18 2001-03-15 Gruenenthal Gmbh Verwendung von Morphinanderivaten als Arzneimittel
WO2003070175A2 (en) * 2002-02-15 2003-08-28 Howard Brooks-Korn Use of opioid compound to treat a neurologic or neurogenic disorder
DE10229842A1 (de) * 2002-07-03 2004-02-05 Helmut Prof. Dr. Schmidhammer Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung
ATE444295T1 (de) 2002-11-08 2009-10-15 Mallinckrodt Inc Verfahren zur herstellung von quaternäre n-alkyl morphinan alkaloid salzen
EP1595541A1 (en) * 2004-05-12 2005-11-16 Alcasynn Pharmaceuticals Gmbh Use of opioid receptor antagonist compounds for the prevention and/or treatment of diseases associated with the target calcineurin
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
JPWO2006064779A1 (ja) * 2004-12-14 2008-06-12 塩野義製薬株式会社 6’位にカルボキシを有するインドロモルヒナン誘導体
WO2007123920A2 (en) * 2006-04-18 2007-11-01 Joseph Nicholas Logan Spinal rod system
MX2009002844A (es) * 2006-09-20 2009-03-30 Mallinckrodt Inc Preparacion de morfinan-6-onas sustituidas y sales e intermediarios de las mismas.
WO2008109156A2 (en) * 2007-03-06 2008-09-12 Mallinckrodt Inc. Process for the preparation of quaternary n-alkyl morphinan alkaloid salts
US9040726B2 (en) 2007-03-06 2015-05-26 Mallinckrodt Llc Process for the preparation of quaternary N-alkyl morphinan alkaloid salts
US8883817B2 (en) * 2007-10-18 2014-11-11 Aiko Biotechnology Combination analgesic employing opioid and neutral antagonist
US8748448B2 (en) 2007-10-18 2014-06-10 Aiko Biotechnology Combination analgesic employing opioid agonist and neutral antagonist
NZ586194A (en) 2007-12-17 2012-07-27 Mallinckrodt Llc Processes for the production of (+)-'nal' morphinan compounds
WO2009132313A2 (en) * 2008-04-25 2009-10-29 Progenics Pharmaceuticals, Inc. Morphinan derivatives of organic and inorganic acids
US8148528B2 (en) * 2008-05-27 2012-04-03 Mallinckrodt Llc Processes and compounds for the preparation of normorphinans
WO2010028004A2 (en) 2008-09-03 2010-03-11 Mallinckrodt Inc. Substituted berbines and processes for their synthesis
EP2340832A1 (en) 2009-12-23 2011-07-06 Universität Innsbruck Morphinan-6-one compounds for the treatment or prevention of neurodegenerative diseases
JP6173431B2 (ja) * 2013-03-08 2017-08-02 学校法人北里研究所 モルヒナン誘導体
WO2015082932A1 (en) 2013-12-05 2015-06-11 The University Of Bath Novel opioid compounds and their uses
WO2020012245A1 (en) 2018-07-13 2020-01-16 Alkermes Pharma Ireland Limited Thienothiophene-naltrexone prodrugs for long-acting injectable compositions
US10799496B2 (en) 2018-07-13 2020-10-13 Alkermes Pharma Ireland Limited Naphthylenyl compounds for long-acting injectable compositions and related methods
WO2020094634A1 (en) 2018-11-05 2020-05-14 Alkermes Pharma Ireland Limited Thiophene prodrugs of naltroxene for long-acting injectable compositions and related methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
JP2906654B2 (ja) * 1989-11-28 1999-06-21 東レ株式会社 免疫抑制剤及びその製造方法
JPH04342529A (ja) * 1991-05-21 1992-11-30 Toray Ind Inc 抗アレルギー剤
US5223507A (en) * 1992-01-21 1993-06-29 G. D. Searle & Co. Method of using opioid compounds as delta opioid selective agonist analgesics
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
DE69332945T2 (de) * 1992-09-29 2004-05-19 Toray Industries, Inc. Indol-derivat, verfahren zu dessen herstellung und dessen medizinische anwendung

Also Published As

Publication number Publication date
AU690996B2 (en) 1998-05-07
JP4117801B2 (ja) 2008-07-16
ATE259815T1 (de) 2004-03-15
ZA953701B (en) 1995-11-20
DE69532580T2 (de) 2004-07-29
EP0759922A1 (en) 1997-03-05
JPH10500131A (ja) 1998-01-06
WO1995031463A1 (en) 1995-11-23
ES2214501T3 (es) 2004-09-16
EP0759922B1 (en) 2004-02-18
DE69532580D1 (de) 2004-03-25
AU2581795A (en) 1995-12-05
US6136817A (en) 2000-10-24
IL113631A0 (en) 1995-08-31

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